January 25, 2021

Download Ebook Free Analysis For Time-to-Event Data Under Censoring And Truncation

Analysis for Time-to-event Data Under Censoring and Truncation

Analysis for Time-to-event Data Under Censoring and Truncation
Author : Hongsheng Dai,Huan Wang
Publisher : Academic Press
Release Date : 2016-10-01
Category :
Total pages :96
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"Survival Analysis for Bivariate Truncated Data" provides readers with a comprehensive review on the existing works on survival analysis for truncated data, mainly focusing on the estimation of univariate and bivariate survival function. The most distinguishing feature of survival data is known as censoring, which occurs when the survival time can only be exactly observed within certain time intervals. A second feature is truncation, which is often deliberate and usually due to selection bias in the study design. Truncation presents itself in different ways. For example, left truncation, which is often due to a so-called late entry bias, occurs when individuals enter a study at a certain age and are followed from this delayed entry time. Right truncation arises when only individuals who experienced the event of interest before a certain time point can be observed. Analyzing truncated survival data without considering the potential selection bias may lead to seriously biased estimates of the time to event of interest and the impact of risk factors. Assists statisticians, epidemiologists, medical researchers, and actuaries who need to understand the mechanism of selection biasReviews existing works on survival analysis for truncated data, mainly focusing on the estimation of univariate and bivariate survival functionOffers a guideline for analyzing truncated survival data

Analysis for Time-to-Event Data under Censoring and Truncation

Analysis for Time-to-Event Data under Censoring and Truncation
Author : Hongsheng Dai,Huan Wang
Publisher : Academic Press
Release Date : 2016-10-06
Category : Mathematics
Total pages :102
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Survival Analysis for Bivariate Truncated Data provides readers with a comprehensive review on the existing works on survival analysis for truncated data, mainly focusing on the estimation of univariate and bivariate survival function. The most distinguishing feature of survival data is known as censoring, which occurs when the survival time can only be exactly observed within certain time intervals. A second feature is truncation, which is often deliberate and usually due to selection bias in the study design. Truncation presents itself in different ways. For example, left truncation, which is often due to a so-called late entry bias, occurs when individuals enter a study at a certain age and are followed from this delayed entry time. Right truncation arises when only individuals who experienced the event of interest before a certain time point can be observed. Analyzing truncated survival data without considering the potential selection bias may lead to seriously biased estimates of the time to event of interest and the impact of risk factors. Assists statisticians, epidemiologists, medical researchers, and actuaries who need to understand the mechanism of selection bias Reviews existing works on survival analysis for truncated data, mainly focusing on the estimation of univariate and bivariate survival function Offers a guideline for analyzing truncated survival data

Survival Analysis

Survival Analysis
Author : John P. Klein,Melvin L. Moeschberger
Publisher : Springer Science & Business Media
Release Date : 2013-06-29
Category : Medical
Total pages :502
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Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.

Survival Analysis Using S

Survival Analysis Using S
Author : Mara Tableman,Jong Sung Kim
Publisher : CRC Press
Release Date : 2003-07-28
Category : Mathematics
Total pages :280
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Survival Analysis Using S: Analysis of Time-to-Event Data is designed as a text for a one-semester or one-quarter course in survival analysis for upper-level or graduate students in statistics, biostatistics, and epidemiology. Prerequisites are a standard pre-calculus first course in probability and statistics, and a course in applied linear regression models. No prior knowledge of S or R is assumed. A wide choice of exercises is included, some intended for more advanced students with a first course in mathematical statistics. The authors emphasize parametric log-linear models, while also detailing nonparametric procedures along with model building and data diagnostics. Medical and public health researchers will find the discussion of cut point analysis with bootstrap validation, competing risks and the cumulative incidence estimator, and the analysis of left-truncated and right-censored data invaluable. The bootstrap procedure checks robustness of cut point analysis and determines cut point(s). In a chapter written by Stephen Portnoy, censored regression quantiles - a new nonparametric regression methodology (2003) - is developed to identify important forms of population heterogeneity and to detect departures from traditional Cox models. By generalizing the Kaplan-Meier estimator to regression models for conditional quantiles, this methods provides a valuable complement to traditional Cox proportional hazards approaches.

Encyclopedia of Measurement and Statistics

Encyclopedia of Measurement and Statistics
Author : Neil J. Salkind
Publisher : SAGE Publications
Release Date : 2006-10-13
Category : Social Science
Total pages :1416
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The Encyclopedia of Measurement and Statistics presents state-of-the-art information and ready-to-use facts from the fields of measurement and statistics in an unintimidating style. The ideas and tools contained in these pages are approachable and can be invaluable for understanding our very technical world and the increasing flow of information. Although there are references that cover statistics and assessment in depth, none provides as comprehensive a resource in as focused and accessible a manner as the three volumes of this Encyclopedia. Through approximately 500 contributions, experts provide an overview and an explanation of the major topics in these two areas.

Introducing Survival and Event History Analysis

Introducing Survival and Event History Analysis
Author : Melinda Mills
Publisher : SAGE
Release Date : 2011-01-19
Category : Social Science
Total pages :279
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This book is an accessible, practical and comprehensive guide for researchers from multiple disciplines including biomedical, epidemiology, engineering and the social sciences. Written for accessibility, this book will appeal to students and researchers who want to understand the basics of survival and event history analysis and apply these methods without getting entangled in mathematical and theoretical technicalities. Inside, readers are offered a blueprint for their entire research project from data preparation to model selection and diagnostics. Engaging, easy to read, functional and packed with enlightening examples, ‘hands-on’ exercises, conversations with key scholars and resources for both students and instructors, this text allows researchers to quickly master advanced statistical techniques. It is written from the perspective of the ‘user’, making it suitable as both a self-learning tool and graduate-level textbook. Also included are up-to-date innovations in the field, including advancements in the assessment of model fit, unobserved heterogeneity, recurrent events and multilevel event history models. Practical instructions are also included for using the statistical programs of R, STATA and SPSS, enabling readers to replicate the examples described in the text.

Epidemiology and Medical Statistics

Epidemiology and Medical Statistics
Author : Anonim
Publisher : Elsevier
Release Date : 2007-11-21
Category : Mathematics
Total pages :870
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This volume, representing a compilation of authoritative reviews on a multitude of uses of statistics in epidemiology and medical statistics written by internationally renowned experts, is addressed to statisticians working in biomedical and epidemiological fields who use statistical and quantitative methods in their work. While the use of statistics in these fields has a long and rich history, explosive growth of science in general and clinical and epidemiological sciences in particular have gone through a see of change, spawning the development of new methods and innovative adaptations of standard methods. Since the literature is highly scattered, the Editors have undertaken this humble exercise to document a representative collection of topics of broad interest to diverse users. The volume spans a cross section of standard topics oriented toward users in the current evolving field, as well as special topics in much need which have more recent origins. This volume was prepared especially keeping the applied statisticians in mind, emphasizing applications-oriented methods and techniques, including references to appropriate software when relevant. · Contributors are internationally renowned experts in their respective areas · Addresses emerging statistical challenges in epidemiological, biomedical, and pharmaceutical research · Methods for assessing Biomarkers, analysis of competing risks · Clinical trials including sequential and group sequential, crossover designs, cluster randomized, and adaptive designs · Structural equations modelling and longitudinal data analysis

Ecological Statistics

Ecological Statistics
Author : Gordon A. Fox,Simoneta Negrete-Yankelevich,Vinicio J. Sosa
Publisher : OUP Oxford
Release Date : 2015-01-29
Category : Science
Total pages :400
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The application and interpretation of statistics are central to ecological study and practice. Ecologists are now asking more sophisticated questions than in the past. These new questions, together with the continued growth of computing power and the availability of new software, have created a new generation of statistical techniques. These have resulted in major recent developments in both our understanding and practice of ecological statistics. This novel book synthesizes a number of these changes, addressing key approaches and issues that tend to be overlooked in other books such as missing/censored data, correlation structure of data, heterogeneous data, and complex causal relationships. These issues characterize a large proportion of ecological data, but most ecologists' training in traditional statistics simply does not provide them with adequate preparation to handle the associated challenges. Uniquely, Ecological Statistics highlights the underlying links among many statistical approaches that attempt to tackle these issues. In particular, it gives readers an introduction to approaches to inference, likelihoods, generalized linear (mixed) models, spatially or phylogenetically-structured data, and data synthesis, with a strong emphasis on conceptual understanding and subsequent application to data analysis. Written by a team of practicing ecologists, mathematical explanations have been kept to the minimum necessary. This user-friendly textbook will be suitable for graduate students, researchers, and practitioners in the fields of ecology, evolution, environmental studies, and computational biology who are interested in updating their statistical tool kits. A companion web site provides example data sets and commented code in the R language.

Survival and Event History Analysis

Survival and Event History Analysis
Author : Odd Aalen,Ornulf Borgan,Hakon Gjessing
Publisher : Springer Science & Business Media
Release Date : 2008-09-16
Category : Mathematics
Total pages :540
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The aim of this book is to bridge the gap between standard textbook models and a range of models where the dynamic structure of the data manifests itself fully. The common denominator of such models is stochastic processes. The authors show how counting processes, martingales, and stochastic integrals fit very nicely with censored data. Beginning with standard analyses such as Kaplan-Meier plots and Cox regression, the presentation progresses to the additive hazard model and recurrent event data. Stochastic processes are also used as natural models for individual frailty; they allow sensible interpretations of a number of surprising artifacts seen in population data. The stochastic process framework is naturally connected to causality. The authors show how dynamic path analyses can incorporate many modern causality ideas in a framework that takes the time aspect seriously. To make the material accessible to the reader, a large number of practical examples, mainly from medicine, are developed in detail. Stochastic processes are introduced in an intuitive and non-technical manner. The book is aimed at investigators who use event history methods and want a better understanding of the statistical concepts. It is suitable as a textbook for graduate courses in statistics and biostatistics.

Analysis of Waiting-Time Data in Health Services Research

Analysis of Waiting-Time Data in Health Services Research
Author : Boris Sobolev,Lisa Kuramoto
Publisher : Springer Science & Business Media
Release Date : 2008-01-03
Category : Medical
Total pages :214
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Why some patients wait longer than others remains an important question. This book is a reference for health services researchers looking for statistical tools with which to study waiting times. The book offers detailed coverage of statistical concepts and methods for the analysis and interpretation of waiting-time data. It provides analysis from health services research perspective, rather than operations management, and contains a collection of examples.

Encyclopedia of Biopharmaceutical Statistics - Four Volume Set

Encyclopedia of Biopharmaceutical Statistics - Four Volume Set
Author : Shein-Chung Chow
Publisher : CRC Press
Release Date : 2018-07-19
Category : Mathematics
Total pages :2780
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Since the publication of the first edition in 2000, there has been an explosive growth of literature in biopharmaceutical research and development of new medicines. This encyclopedia (1) provides a comprehensive and unified presentation of designs and analyses used at different stages of the drug development process, (2) gives a well-balanced summary of current regulatory requirements, and (3) describes recently developed statistical methods in the pharmaceutical sciences. Features of the Fourth Edition: 1. 78 new and revised entries have been added for a total of 308 chapters and a third volume has been added to encompass the increased number of chapters. 2. Revised and updated entries reflect changes and recent developments in regulatory requirements for the drug review/approval process and statistical designs and methodologies. 3. Additional topics include multiple-stage adaptive trial design in clinical research, translational medicine, design and analysis of biosimilar drug development, big data analytics, and real world evidence for clinical research and development. 4. A table of contents organized by stages of biopharmaceutical development provides easy access to relevant topics. About the Editor: Shein-Chung Chow, Ph.D. is currently an Associate Director, Office of Biostatistics, U.S. Food and Drug Administration (FDA). Dr. Chow is an Adjunct Professor at Duke University School of Medicine, as well as Adjunct Professor at Duke-NUS, Singapore and North Carolina State University. Dr. Chow is the Editor-in-Chief of the Journal of Biopharmaceutical Statistics and the Chapman & Hall/CRC Biostatistics Book Series and the author of 28 books and over 300 methodology papers. He was elected Fellow of the American Statistical Association in 1995.

Statistical Methods in Healthcare

Statistical Methods in Healthcare
Author : Frederick W. Faltin,Ron S. Kenett,Fabrizio Ruggeri
Publisher : John Wiley & Sons
Release Date : 2012-07-24
Category : Medical
Total pages :520
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In recent years the number of innovative medicinal products and devices submitted and approved by regulatory bodies has declined dramatically. The medical product development process is no longer able to keep pace with increasing technologies, science and innovations and the goal is to develop new scientific and technical tools and to make product development processes more efficient and effective. Statistical Methods in Healthcare focuses on the application of statistical methodologies to evaluate promising alternatives and to optimize the performance and demonstrate the effectiveness of those that warrant pursuit is critical to success. Statistical methods used in planning, delivering and monitoring health care, as well as selected statistical aspects of the development and/or production of pharmaceuticals and medical devices are also addressed. With a focus on finding solutions to these challenges, this book: Provides a comprehensive, in-depth treatment of statistical methods in healthcare, along with a reference source for practitioners and specialists in health care and drug development. Offers a broad coverage of standards and established methods through leading edge techniques. Uses an integrated, case-study based approach, with focus on applications. Looks at the use of analytical and monitoring schemes to evaluate therapeutic performance. Features the application of modern quality management systems to clinical practice, and to pharmaceutical development and production processes. Addresses the use of modern Statistical methods such as Adaptive Design, Seamless Design, Data Mining, Bayesian networks and Bootstrapping that can be applied to support the challenging new vision. Practitioners in healthcare-related professions, ranging from clinical trials to care delivery to medical device design, as well as statistical researchers in the field, will benefit from this book.

Survival Analysis

Survival Analysis
Author : Xian Liu
Publisher : John Wiley & Sons
Release Date : 2012-06-13
Category : Mathematics
Total pages :427
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Survival analysis concerns sequential occurrences of events governed by probabilistic laws. Recent decades have witnessed many applications of survival analysis in various disciplines. This book introduces both classic survival models and theories along with newly developed techniques. Readers will learn how to perform analysis of survival data by following numerous empirical illustrations in SAS. Survival Analysis: Models and Applications: Presents basic techniques before leading onto some of the most advanced topics in survival analysis. Assumes only a minimal knowledge of SAS whilst enabling more experienced users to learn new techniques of data input and manipulation. Provides numerous examples of SAS code to illustrate each of the methods, along with step-by-step instructions to perform each technique. Highlights the strengths and limitations of each technique covered. Covering a wide scope of survival techniques and methods, from the introductory to the advanced, this book can be used as a useful reference book for planners, researchers, and professors who are working in settings involving various lifetime events. Scientists interested in survival analysis should find it a useful guidebook for the incorporation of survival data and methods into their projects.

Analysis of Survival Data with Dependent Censoring

Analysis of Survival Data with Dependent Censoring
Author : Takeshi Emura,Yi-Hau Chen
Publisher : Springer
Release Date : 2018-04-05
Category : Medical
Total pages :84
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This book introduces readers to copula-based statistical methods for analyzing survival data involving dependent censoring. Primarily focusing on likelihood-based methods performed under copula models, it is the first book solely devoted to the problem of dependent censoring. The book demonstrates the advantages of the copula-based methods in the context of medical research, especially with regard to cancer patients’ survival data. Needless to say, the statistical methods presented here can also be applied to many other branches of science, especially in reliability, where survival analysis plays an important role. The book can be used as a textbook for graduate coursework or a short course aimed at (bio-) statisticians. To deepen readers’ understanding of copula-based approaches, the book provides an accessible introduction to basic survival analysis and explains the mathematical foundations of copula-based survival models.

The Statistical Analysis of Interval-censored Failure Time Data

The Statistical Analysis of Interval-censored Failure Time Data
Author : Jianguo Sun
Publisher : Springer
Release Date : 2007-05-26
Category : Mathematics
Total pages :304
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This book collects and unifies statistical models and methods that have been proposed for analyzing interval-censored failure time data. It provides the first comprehensive coverage of the topic of interval-censored data and complements the books on right-censored data. The focus of the book is on nonparametric and semiparametric inferences, but it also describes parametric and imputation approaches. This book provides an up-to-date reference for people who are conducting research on the analysis of interval-censored failure time data as well as for those who need to analyze interval-censored data to answer substantive questions.