January 18, 2021

Download Ebook Free Anti-Cancer Treatments And Cardiotoxicity

Anticancer Treatments and Cardiotoxicity

Anticancer Treatments and Cardiotoxicity
Author : Patrizio Lancellotti,Jose L Zamorano,Maurizio Galderisi
Publisher : Academic Press
Release Date : 2016-11-11
Category : Medical
Total pages :470
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Anticancer Treatments and Cardiotoxicity: Mechanisms, Diagnostic and Therapeutic Interventions presents cutting edge research on the adverse cardiac effects of both radiotherapy and chemotherapy, brought together by leaders in the field. Cancer treatment-related cardiotoxicity is the leading cause of treatment-associated mortality in cancer survivors and is one of the most common post-treatment issues among survivors of adult cancer. Early detection of the patients prone to developing cardiotoxicity, taking in to account the type of treatment, history and other risk factors, is essential in the fight to decrease cardiotoxic mortality. This illustrated reference describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment. In addition, new guidelines on imaging for the screening and monitoring of these patients are also presented. Anticancer Treatments and Cardiotoxicity is an essential reference for those involved in the research and treatment of cardiovascular toxicity. Provides algorithms essential for the use of imaging, and biomarkers for the screening and monitoring of patients Written by world-leading experts in the field of cardiotoxicity Includes high-quality images, case studies, and test questions Describes the most effective diagnostic and imaging tools to evaluate and predict the development of cardiac dysfunction for those patients undergoing cancer treatment

Anti-Cancer Treatments and Cardiotoxicity

Anti-Cancer Treatments and Cardiotoxicity
Author : Patrizio Lancellotti,Jose L. Zamorano,Maurizio Galderisi
Publisher : Academic Press
Release Date : 2016-06-01
Category : Medical
Total pages :300
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Cardio-Oncology

Cardio-Oncology
Author : Roberta A. Gottlieb,Puja K Mehta
Publisher : Academic Press
Release Date : 2016-11-26
Category : Medical
Total pages :356
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Cardio-Oncology: Principles, Prevention and Management is a clinical volume that focuses on the basic science of cardio-oncology, addresses cardiotoxicity as a consequence of cancer therapy, and discusses prevention, diagnosis and management of cardiovascular disease in patients with cancer. This comprehensive volume presents unique perspectives ranging from basic science to clinical medicine in the field of cardio-oncology. It would be a valuable resource for cardiologists, oncologists, internists, and pediatricians caring for patients with cancer who have cardiovascular risk factors, as well as for cardio-oncology researchers. Covers basic science of cardio-oncology to provide readers with the necessary background Addresses cardiotoxicity related to current cancer therapeutic modalities Discusses diagnostic and management approaches of patients with underlying cardiac risk factors as well as otherwise healthy cancer patients

Cardiotoxicity

Cardiotoxicity
Author : Wenyong Tan
Publisher : BoD – Books on Demand
Release Date : 2018-11-14
Category : Medical
Total pages :162
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Cardiotoxicity may be caused by radiotherapy and/or anticancer agents for many malignancies, adverse effects of some drugs in the context of medical intervention or heavy metal intake, especially during the anticancer therapy. This book intends to bring forward the recent development in toxicities from cancer treatment. It updates the possible mechanisms of cardiotoxicities of some anticancer agents and the suggested prevention and treatment strategies. This book contains many valuable contributions from the researchers in oncology and cardiology as well as the clinicians who are experts in this field.

Cardio-Oncology

Cardio-Oncology
Author : Gretchen G. Kimmick,Daniel J. Lenihan,Douglas B. Sawyer,Erica L. Mayer,Dawn L. Hershman
Publisher : Springer
Release Date : 2017-04-11
Category : Medical
Total pages :319
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Co-edited and written by an interdisciplinary team of experts in oncology and cardiology, this book is a clinically useful resource on these overlapping topics: • Cardiac complications in patients receiving cancer therapy • The treatment of cancer in patients with cardiovascular disease • The treatment of cardiovascular disease in patients with cancer When relevant to medical practice, epidemiology and basic science are also included in the discussion and each chapter is written by an oncologist and a cardiologist. Additionally, the chapters follow a similar format to make the book truly interdisciplinary, user-friendly, and clinically applicable to specialists and non-specialists who care for patients with both cancer and cardiovascular disease.

Pediatric Cancer Survivors

Pediatric Cancer Survivors
Author : Karen Wonders,Brittany Stout
Publisher : BoD – Books on Demand
Release Date : 2017-06-07
Category : Medical
Total pages :114
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Pediatric cancer develops in 1 to 500 children. Typically, the type of cancers that develop in children is different than those that develop in adults, in that they are often the result of a DNA mutation rather than environmental or lifestyle risk factors. Leukemia, brain and central nervous system tumors, and neuroblastomas are the most common cancer types in child populations. Children tend to respond better to anticancer treatments, including chemotherapy and radiation. However, long-term side effects are common in children, often requiring follow-up care and lifestyle intervention for the rest of their lives. The percentage of 5-year survivors was over 50% for the most common cancers. This suggests that a majority of cancers in this population are highly survivable. As such, research should focus on aspects of survivorship for these individuals. This book will explore issues related to pediatric cancer and their associated treatments.

Cancer and the Heart

Cancer and the Heart
Author : Michael S. Ewer,Edward T. H. Yeh, M.D.
Publisher : PMPH-USA
Release Date : 2013
Category : Medical
Total pages :492
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The book begins with the basic science behind the medical applications of the knowledge: cardiovascular biology, pathways, and their relationship to cancer treatment and principles of chemotherapy and immunotherapy. The second section consists of an overview and classification of anti-cancer drugs and a look at their cardiotoxicity. The third section looks at cardiac imaging in the cancer patient, including cardiac ultrasound, Doppler imaging, nuclear imaging, magnetic resonance imaging, and computed tomography in the cancer patient. In section four, management of cardiac disease in the cancer patient is discussed, including cardiac rhythm disturbances and heart failure. Cardiac emergencies and interventions are described as is preoperative assessment of the cancer patient for non- cardiovascular surgery. The final section includes a range of topics such as the pericardium, cardiovascular effects of endocrine treatments, primary cardiac tumors and malignancies of the myocardium and pericardium. Cardiac monitoring during clinical trials and pulmonary concerns are also addressed, as are psychosocial, social, economic, and legal issues of the cancer patient with heart disease.

Cardiac Complications of Cancer Therapy

Cardiac Complications of Cancer Therapy
Author : Anecita P. Fadol
Publisher : Unknown
Release Date : 2013-01-01
Category : Medical
Total pages :305
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Cardiac complications of anticancer therapy represent an emerging clinical issue in both established chemotherapeutics as well as novel molecular therapies. As a result, healthcare providers are under greater pressure to be vigilant in evaluating patients with cancer for acute and chronic or late physical effects of cancer therapy some of which could be life-threatening. Cardiac Complications of Cancer Therapy, edited by Anecita P. Fadol, PhD, RN, FNP-BC, FAANP, provides you with the essentials of clinical management of the most common cardiac complications of cancer therapy. While you can find a multitude of literature on the management of cardiac problems, including both texts and journal articles, no other clinical reference book on the current market is written for nurses and midlevel providers and examines both the complexity of cardiac problems in conjunction with a cancer diagnosis. Describing the assessment and management of common cardiac problems, chapters in this quick-reference guide examine issues such as cardiovascular anatomy, the development of cardiotoxicity and the management of cardiomyopathy in patients with cancer, targeted therapies and cardiomyopathy, acute coronary syndromes in patients with cancer, cardiac inflammatory conditions and cardiac tamponade in patients with cancer, hypertension in patients with cancer, heart failure in patients with cancer, screening and management of cardiovascular risk factors in cancer survivors, and much more.

Cardio-Oncology: From Bench to Bedside

Cardio-Oncology: From Bench to Bedside
Author : Jun-ichi Abe,Anil K. Sood,James Martin
Publisher : Frontiers Media SA
Release Date : 2019-05-17
Category :
Total pages :113
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Cardio-oncology is a medical subspecialty concerned with the diagnosis and treatment of cardiovascular disease (CVD) and organ failure mediated by micro- to macro-circulation defects in cancer patients and survivors. The risk of CVD in cancer survivors is eight times higher than the general population, and the relative risk of coronary artery disease and heart failure (HF) is 10 times and 15 times higher, respectively, compared to their siblings without cancer. It is important to note that cancer treatments including chemotherapy and radiation can lead to both short- (< 1 year) and long-term (> 5 years) cardiovascular complications. Previously, Dr. Edward T.H. Yeh initiated the MD Anderson Practice (MAP) project, and published 16 MAPs to provide the current best practice we considered at UT MD Anderson. As shown in these MAPs, one of the key issues of cardio-oncology practice and science is how we can allow cancer patients to receive maximum and uninterrupted treatments for cancer while protecting them from cancer therapy-mediated cardiovascular complications. Therefore, it is crucial to understand not only pathophysiology of CVD, but also mechanistic insights of how each cancer treatment can control cancer growth and metastasis. Without having the profound knowledge in the pathophysiological, clinical and epidemiologic aspects of cardiovascular complications of existing cancer therapy, it is impossible to establish the strong evidence-based strategies and approaches for both short- and long-term cardiovascular complications after cancer treatment. In addition, we believe that cardio-oncology science should not be restricted to deal with the side effects of each specific cancer drug, because many common cardiovascular phenotypes among the different cancer treatments are also observed. This Research Topic provides a comprehensive overview from both of the current research and practice, and a platform for obtaining the logical and up-to-date treatment and prevention of CVD in cancer patients and survivors.

Mechanical Ventilation in Critically Ill Cancer Patients

Mechanical Ventilation in Critically Ill Cancer Patients
Author : Antonio M. Esquinas,S. Egbert Pravinkumar,Ayman O. Soubani
Publisher : Springer
Release Date : 2018-02-07
Category : Medical
Total pages :368
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This book aims to equip the reader to make optimal decisions on the use of mechanical ventilatory support in critically ill cancer patients with acute respiratory failure (ARF) and to implement the different strategies effectively. Detailed information is provided on the rationale for invasive and non-invasive ventilation, the different modes of ventilation, indications and contraindications, prognostic factors, and outcomes. The role of postoperative mechanical ventilation following various forms of surgery is extensively addressed, and key aspects of withdrawal from ventilatory support are discussed. Attention is also devoted to mechanical ventilation in the palliative care context. The concluding part of the book focuses on healthcare resource utilization and organizational support in cancer critical care. ARF is the most common reason for hospital and intensive care admission among oncological patients, and there is growing evidence that outcome following mechanical ventilation is improving. Readers will find this book to be an invaluable aid when selecting and executing a strategy for management of ARF in individual cancer patients.

Cancer Treatment

Cancer Treatment
Author : Letícia Rangel
Publisher : BoD – Books on Demand
Release Date : 2013-05-09
Category : Medical
Total pages :630
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Cancer Treatment: Conventional and Innovative Approaches is an attempt to integrate into a book volume the various aspects of cancer treatment, compiling comprehensive reviews written by an international team of experts in the field. The volume is presented in six sections: i) Section 1: Cancer treatment: Conventional and innovative pharmacological approaches; ii) Section 2: Combinatorial strategies to fight cancer: Surgery, radiotherapy, backytherapy, chemotherapy, and hyperthermia; iii) Section 3: The immunotherapy of cancer; iv) Section 4: Multidisciplinarity in cancer therapy: nutrition and beyond; v) Section 5: Supportive care for cancer patients; vi) Section 6: Perspectives in cancer biology and modeling. Ultimately, we hope this book can enlighten important issues involved in the management of cancer, summarizing the state-of-the-art knowledge regarding the disease control and treatment; thus, providing means to improve the overall care of patients that daily battle against this potentially lethal condition.

Cardiovascular Complications in Cancer Therapy

Cardiovascular Complications in Cancer Therapy
Author : Antonio Russo,Giuseppina Novo,Patrizio Lancellotti,Antonio Giordano,Fausto J. Pinto
Publisher : Springer
Release Date : 2018-10-04
Category : Medical
Total pages :224
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This proposed text is designed to provide a useful and comprehensive resource and state-of-the-art overview to readers about vascular damage potentially induced by antineoplastic drugs. Thanks to more and more effective antineoplastic treatments the survival of cancer patients is enormously increasing, but at the same time it is increasing the burden of related cardiovascular complications that affect morbidity and mortality. On this basis a new branch of cardiology has been developed, that is Cardio-Oncology. The aim is to prevent cardiovascular complications related to cancer therapy and to facilitate and avoid interruption of antineoplastic drugs due to the occurrence of cardiovascular damage. An increasing attention has been given to cardiac damage, while, until today, vascular complications have been poorly evaluated. The aim of this book is to focus on vascular complications related to cancer treatment, to guide the clinician at facing, during his every day practice, cardiovascular toxicity in cancer and hematologic patients. The proposed sections of the book have been structured to review the molecular mechanisms underlying vascular damage induced by new and old treatments, to describe the various manifestations of vascular disease that may range from artery to venous disease (including coronary artery disease, peripheral arterial disease, venous thromboembolism and pulmonary hypertension), and to provide advice to monitor patients undergoing onco-hematologic treatments in order to prevent and eventually manage vascular damage.This book will address resident and fellow physicians, medical oncologists, cardiologists, general practitioners and all those who take care of these patients.All invited authors will be recognized experts in their field, and leading international researchers on these topics. The editor has worked with these expert colleagues on a variety of other projects. The authors will provide their manuscript according to current literature and clinical research studies. The book does not seek to duplicate or replace other current resources. Rather, it will create a comprehensive yet concise resource on this emerging topic that is not adequately covered by any current literature.

Cancer Medicine

Cancer Medicine
Author : James F. Holland
Publisher : Unknown
Release Date : 1997
Category : Cancer
Total pages :3467
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Emerging Challenges of Cardiovascular and Metabolic Dysfunctions in Cardio-oncology: From Bench to Bedside

Emerging Challenges of Cardiovascular and Metabolic Dysfunctions in Cardio-oncology: From Bench to Bedside
Author : Canan G. Nebigil,Tienush Rassaf,Michael W.Y. Chan
Publisher : Frontiers Media SA
Release Date : 2020-10-27
Category : Medical
Total pages :129
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Toxicology Studies

Toxicology Studies
Author : Ana Cristina Andreazza,Gustavo Scola
Publisher : BoD – Books on Demand
Release Date : 2015-07-08
Category : Medical
Total pages :244
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The increased exposure to toxins, toxicants and novel drugs has promoted toxicology to become one of the most important areas of research with emerging innovative toxicity testing protocols, techniques, and regulation being placed. Since the bioactivation of many toxins and toxicants and its consequences on human health are not clearly known, this book offers a quick overview of cellular toxicology through the cell, drug and environmental toxicity. This book does not strive to be comprehensive but instead offers a quick overview of principle aspects of toxins and toxicants in order to familiarize the key principles of toxicology. The book is divided into three main sections,; the first one discusses the role of mitochondrial dysfunction, oxidative stress and mitochondrial drug development. The second and third sections bring light to forensic toxicology and drug poisoning followed by environmental toxicity.