December 5, 2020

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Bio-nanoimaging

Bio-nanoimaging
Author : Vladimir Uversky,Yuri Lyubchenko
Publisher : Academic Press
Release Date : 2013-11-05
Category : Technology & Engineering
Total pages :552
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Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties. Provides practical examples of nanoimaging research from leading molecular biology, cell biology, protein chemistry, biotechnology, genetics, and pharmaceutical labs Includes over 200 color images to illustrate the power of various nanoimaging technologies Focuses on nanoimaging techniques applied to protein misfolding and aggregation in molecular medicine

Bionanotechnology

Bionanotechnology
Author : Elisabeth S. Papazoglou,Aravind Parthasarathy
Publisher : Morgan & Claypool Publishers
Release Date : 2007
Category : Medical
Total pages :139
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""This book aims to provide vital information about the growing field of bionanotechnology for undergraduate and graduate students, as well as working professionals in various fields.The fundamentals of nanotechnology are covered along with several specific bionanotechnology applications, including nanobioimaging and drug delivery which is a growing $100 billions industry.The uniqueness of the field has been brought out with unparalleled lucidity; a balance between important insight into the synthetic methods of preparing stable nano-structures and medical applications-driven focus educates and informs the reader on the impact of this emerging field. Critical examination of potential threats followed by a current global outlook completes the discussion. In short, the book takes you through a journey from fundamentals to frontiers of bionanotechnology so that you can understand and make informed decisions on the impact of bionano on your career and business"--Book jacket.

Neurophotonics and Biomedical Spectroscopy

Neurophotonics and Biomedical Spectroscopy
Author : Robert R. Alfano,Lingyan Shi
Publisher : William Andrew
Release Date : 2018-11-22
Category : Technology & Engineering
Total pages :610
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Neurophotonics and Biomedical Spectroscopy addresses the novel state-of-the-art work in non-invasive optical spectroscopic methods that detect the onset and progression of diseases and other conditions, including pre-malignancy, cancer, Alzheimer’s disease, tissue and cell response to therapeutic intervention, unintended injury and laser energy deposition. The book then highlights research in neurophotonics that investigates single and multi-photon excitation optical signatures of normal/diseased nerve tissues and in the brain, providing a better understanding of the underlying biochemical and structural changes of tissues and cells that are responsible for the observed spectroscopic signatures. Topics cover a wide array of well-established UV, visible, NIR and IR optical and spectroscopic techniques and novel approaches to diagnose tissue changes, including: label free in vivo and ex vivo fluorescence spectroscopy, Stoke shift spectroscopy, spectral imaging, Resonance Raman spectroscopy, multiphoton two Photon excitation, and more. Provides an overview of the spectroscopic properties of tissue and tissue-light interaction, describing techniques to exploit these properties in imaging Explores the potential and significance of molecule-specific imaging and its capacity to reveal vital new information on nanoscale structures Offers a concise overview of different spectroscopic methods and their potential benefits for solving diagnostic and therapeutic problems

Nanoscopy and Multidimensional Optical Fluorescence Microscopy

Nanoscopy and Multidimensional Optical Fluorescence Microscopy
Author : Alberto Diaspro
Publisher : CRC Press
Release Date : 2010-04-26
Category : Technology & Engineering
Total pages :448
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"Alberto Diaspro has been choreographing light’s dance for over 20 years, and in Nanoscopy and Multidimensional Optical Fluorescence Microscopy, he has assembled a diverse group of experts to explain the methods they use to coax light to reveal biology’s secrets." — From the Foreword by Daniel Evanko, editor, Nature Methods Nanoscopy and Multidimensional Optical Fluorescence Microscopy demonstrates that the boundaries between sciences do blur at the bottom, especially those that might separate the optical work of physicists and the cellular work of microbiologists. In 18 chapters written by pioneering researchers, this work offers the first comprehensive and current documentation of the cutting-edge research being accomplished in a wide range of photonic devices with revolutionary application. The highlight of the book is its coverage of optical nanoscopy and super-resolution microscopy. The rapid advances in this area over the past few years offer researchers in both photonics and molecular biologya wealth of accomplishment upon which they can build. Offering a complete treatment of this emerging field, this volume: Describes how scientists have exploited the properties of light and its fluorophore partners to overcome the resolution limit of conventional light microscopy Delves into recent ways to minimize the photobleaching that has long hampered many methods including those that have the potential to capture previously unobtainable information on the movements of single molecules Discusses the principles, benefits, and implementation of fluorescence correlation spectroscopy and related methods, which simplifies analysis by limiting light to stationary focal points in a sample Considers the most basic as well as emerging methods for improving three-dimensional optical sectioning microscopy Reviews the basics of FRET (fluorescence resonance energy transfer) and considers its new use for investigating protein complexes The text also introduces those emerging nonfluorescence microscopy methods that can actually exert mechanical forces to trap and move a variety of objects ranging from beads to living cells and cellular organelles. Combining this technique with fluorescence microscopy provides an unparalleled ability to manipulate and visualize biological samples. In the half-century since Richard Feynman challenged scientists to come up with the tools to investigate and manipulate our world at the nanoscale, we have succeeded in placing tools in the hands of biophysicists that are leading to major breakthroughs in our understanding of life and our ability to diagnose, treat, and prevent many challenges to human health. This book reflects what has been accomplished to date while pointing the way to what still needs to be done.

Interfacing Optics with Biology -- Optical Sensors, Actuators and Protein Lithography

Interfacing Optics with Biology -- Optical Sensors, Actuators and Protein Lithography
Author : Sheng Wang
Publisher : Unknown
Release Date : 2009
Category :
Total pages :246
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Protein Misfolding

Protein Misfolding
Author : Rossen Donev
Publisher : Academic Press
Release Date : 2020-01-13
Category : Science
Total pages :450
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Protein Misfolding, Volume 118, covers the wide spectrum of diseases and disorders that are attributed to protein misfolding, including degenerative and neurodegenerative, cardiovascular, renal, glaucoma, cancer, cystic fibrosis, Gaucher's disease, and many others. Specific chapters cover Mass spectrometric approaches for profiling protein folding and stability, Biomembranes, a key player in protein misfolding, how Genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases, Formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, Protein misfolding in ER stress with applications to cardiovascular and renal disease, and much more. Integrates methods for studying protein misfolding, factors that trigger this process and its role in a wide spectrum of diseases and disorders Contains timely chapters written by well-renowned authorities in their field Provides data that is well supported by a number of high quality illustrations, figures and tables, and targets a very wide audience of specialists, researchers and students

State of the Art in Nano-bioimaging

State of the Art in Nano-bioimaging
Author : Morteza Sasani Ghamsari
Publisher : BoD – Books on Demand
Release Date : 2018-06-20
Category : Science
Total pages :114
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Nano-bioimaging is a real-time observation method for the study of biological processes in subcellular structures and entire cells. This technique aims to interfere as little as possible with life processes using nanoscale materials and probes. In this method, nanoscale photon source is often used for imaging, and 3D structure of the observed specimen is studied in detail without physical interference. Over the last decade, further boost in bioimaging has led to increase the nano-bioimaging impact that includes many improvements in the data analysis method, image processing, and molecular imaging technology. However, to increase the usage of nano-bioimaging, several developments in the field of diagnosis accuracy, photobleaching prevention, and controlling of the fluorescence resonance energy transfer (FRET) must be achieved. The purpose of this book is to provide a perspective on the current status of nano-bioimaging technologies.

Radiation in Medicine and Biology

Radiation in Medicine and Biology
Author : Pandit B. Vidyasagar,Sagar S. Jagtap,Omprakash Yemul
Publisher : CRC Press
Release Date : 2017-05-08
Category : Medical
Total pages :218
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This book focuses on the conventional and emerging applications of radiations, which include radio waves and ultraviolet and gamma radiations. It discusses new techniques in radiation therapy and the effects of ionizing radiations on biological systems. The applications of radiations in the synthesis and use of nanoparticles along with the effects of hypergravity indicate a new trend. The book offers a concise account of the latest studies carried out so far and shows the new initiatives to be undertaken in the field of medicine and biology. It covers the medical use of radiations, such as ferrous sulfate–benzoic acid–xylenol orange dosimetry, Co-60 tomotherapy, radio-electro-chemotherapy, and fractional radiotherapy, and radiobiological effects, such as the effects of cell phone radiations on human health parameters and the combined effects of radiations and hypergravity on plants.

Advances in Functional Micro-/Nanoimaging Probes

Advances in Functional Micro-/Nanoimaging Probes
Author : Zhe Liu
Publisher : Springer
Release Date : 2018-09-01
Category : Technology & Engineering
Total pages :117
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This book highlights the latest advances in functional micro/nano imaging probes and their applications for biomedical imaging and therapy. Given the rapid emergence of transdisciplinary research and applications in materials, chemical probes and translational medicine in recent years, scientists in these areas are expected to keep up to date on the latest technologies and advances to promote comprehensive innovations. Addressing this need, the book presents recently introduced features, emerging techniques, and new strategies, complemented by detailed illustrations. Covering the status quo and offering an outlook on the future, it benefits all readers with an interest in functional materials, especially micro/nano imaging materials for biomedical imaging applications, providing them with both vital updates and inspiration for their own research.

Ultrafast Dynamics at the Nanoscale

Ultrafast Dynamics at the Nanoscale
Author : Stefan Haacke,Irene Burghardt
Publisher : CRC Press
Release Date : 2017-01-06
Category : Science
Total pages :528
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Ultrafast Dynamics at the Nanoscale provides a combined experimental and theoretical insight into the molecular-level investigation of light-induced quantum processes in biological systems and nanostructured (bio)assemblies. Topics include DNA photostability and repair, photoactive proteins, biological and artificial light-harvesting systems, plasmonic nanostructures, and organic photovoltaic materials, whose common denominator is the key importance of ultrafast quantum effects at the border between the molecular scale and the nanoscale. The functionality and control of these systems have been under intense investigation in recent years in view of developing a detailed understanding of ultrafast nanoscale energy and charge transfer, as well as fostering novel technologies based on sustainable energy resources. Both experiment and theory have made big strides toward meeting the challenge of these truly complex systems. This book, thus, introduces the reader to cutting-edge developments in ultrafast nonlinear optical spectroscopies and the quantum dynamical simulation of the observed dynamics, including direct simulations of two-dimensional optical experiments. Taken together, these techniques attempt to elucidate whether the quantum coherent nature of ultrafast events enhances the efficiency of the relevant processes and where the quantum–classical boundary sets in, in these high-dimensional biological and material systems. The chapters contain well-illustrated accounts of the authors’ research work, including didactic introductory material, and address a multidisciplinary audience from chemistry, physics, biology, and materials sciences. The book is, therefore, a must-have for graduate- and postgraduate-level researchers who wish to learn about molecular nanoscience from a combined spectroscopic and theoretical viewpoint.

Chemical Engineering Progress

Chemical Engineering Progress
Author : Anonim
Publisher : Unknown
Release Date : 2006
Category : Chemical engineering
Total pages :129
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Biophotonics Micro- and Nano-imaging

Biophotonics Micro- and Nano-imaging
Author : D. Anselmetti
Publisher : Society of Photo Optical
Release Date : 2004
Category : Technology & Engineering
Total pages :132
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Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.

Electrochemical DNA Biosensors

Electrochemical DNA Biosensors
Author : Mehmet Sengun Ozsoz
Publisher : CRC Press
Release Date : 2012-04-23
Category : Science
Total pages :400
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This book focuses on the basic electrochemical applications of DNA in various areas, from basic principles to the most recent discoveries. The book comprises theoretical and experimental analysis of various properties of nucleic acids, research methods, and some promising applications. The topics discussed in the book include electrochemical detection of DNA hybridization based on latex/gold nanoparticle and nanotubes; nanomaterial-based electrochemical DNA detection; electrochemical detection of microorganism-based DNA biosensors; gold nanoparticle-based electrochemical DNA biosensors; electrochemical detection of the aptamer-target interaction; nanoparticle-induced catalysis for DNA biosensing; basic terms regarding electrochemical DNA (nucleic acids) biosensors; screen-printed electrodes for electrochemical DNA detection; application of field-effect transistors to label free electrical DNA biosensor arrays; and electrochemical detection of nucleic acids using branched DNA amplifiers.

New Visions in Plant Science

New Visions in Plant Science
Author : Özge Çelik
Publisher : BoD – Books on Demand
Release Date : 2018-09-19
Category : Science
Total pages :170
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Over the past decade, progress in plant science and molecular technologies has grown considerably. This book focuses on plant biotechnology applications specializing in certain aspects of breeding and molecular marker-assisted selection processes, omic strategies, usage of bioinformatic tools, and nanotechnological improvements in agricultural sciences. Most farmers and breeders can no longer simply turn to the older strategies, and new instructions are needed to adapt their systems to achieve their production goals. The book covers new information on using metabolomics and nanotechnology in agriculture. In these circumstances, all new data and technology are very important in plant science. The topics in this book are practical and user-friendly. They allow practitioners, students, and academicians with specific background knowledge to feel confident about the principles presented on a new generation of molecular plant biotechnology applications.

Nanobiotechnology

Nanobiotechnology
Author : Alok Dhawan,Sanjay Singh,Ashutosh Kumar,Rishi Shanker
Publisher : CRC Press
Release Date : 2018-03-26
Category : Medical
Total pages :494
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This book combines the contributions from the experts of material science, molecular biology, toxicology bio-organic and bio-inorganic chemistry, toxicologists and environmental and food technology etc. to fathom the full scope of current and future of developments in the area of Nanobiotechnology. This book can also be used as text book for graduate students as an essential reference material, and as an reading material for general readers having a curiosity in Nanobiotechnology.