November 23, 2020

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Bioactive Natural Products

Bioactive Natural Products
Author : Goutam Brahmachari
Publisher : John Wiley & Sons
Release Date : 2015-03-23
Category : Science
Total pages :544
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Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Bioactive Natural Products

Bioactive Natural Products
Author : Steven M. Colegate,Russell J. Molyneux
Publisher : CRC Press
Release Date : 2007-12-14
Category : Medical
Total pages :624
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Bioactive natural products are proving to be a rich source of novel therapeutics to both protect against and combat diseases, as well as serve as lead compounds in crop protection. Following the successful format of the first edition, this volume brings together collective research from many new contributors and emphasizes the rationale behind the

Bioactive Natural Products

Bioactive Natural Products
Author : Goutam Brahmachari
Publisher : World Scientific
Release Date : 2012
Category : Electronic books
Total pages :670
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Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations.

Bioactive Natural Products Detection, Isolation, and Structural Determination

Bioactive Natural Products Detection, Isolation, and Structural Determination
Author : Steven M. Colegate,Russell J. Molyneux
Publisher : CRC Press
Release Date : 1993-09-29
Category : Science
Total pages :544
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Bioactive Natural Products covers all the aspects of bioactive natural product research from ethnobotanical investigations to modern, technologically assisted isolation and structural determination of active compounds. An internationally selected group of experts share their knowledge of a wide range of bioactivities and chemical compound classes. Topics in the chapters describing the modern application of detection, isolation, and structural determination techniques are strongly supported by chapters detailing and reviewing research involving various classes of bioactivity. Research areas include the immunomodulatory, antiviral, cytotoxic, anti-inflammatory, and insect behavior classes of bioactivity. Extensive referencing throughout the text is helpful to those readers not familiar with this subject and serves as a critical review for more experienced researchers. The book is also excellent for upper division or post-graduate courses.

Bioactive Natural products in Drug Discovery

Bioactive Natural products in Drug Discovery
Author : Joginder Singh,Vineet Meshram,Mahiti Gupta
Publisher : Springer Nature
Release Date : 2020-04-30
Category : Medical
Total pages :733
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This book highlights different natural products that are derived from the plants and microbes that have shown potential as the lead compounds against infectious diseases and cancer. Natural products represent an untapped source of strikingly diverse chemotypes with novel mechanisms of action and the potential to serve as anticancer and anti-infective agents. The book discusses a range of biotechnologically valuable bioactive compounds and secondary metabolites that have been derived from plant and microorganisms from various ecological niches. It also reviews the latest developments in the field of genomics, bioinformatics and industrial fermentation for harnessing the microbial products for commercial applications. In turn, the book’s closing section reviews important biotechnological applications of various natural products. Combining the expertise of specialists in this field, the book’s goal is to promote the further investigation of natural sources for the development of standardized, safe and effective therapies.

Total Synthesis of Bioactive Natural Products

Total Synthesis of Bioactive Natural Products
Author : Goutam Brahmachari
Publisher : Elsevier
Release Date : 2019-04-27
Category : Science
Total pages :350
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Total Synthesis of Bioactive Natural Products provides step-by-step guidelines for effectively synthesizing the most promising bioactive agents from a broad range of natural products. Beginning with a concise background that outlines the benefits and challenges faced in effective synthesis, the book goes on to provide individual outlines for approximately 100 of the most promising bioactive agents. Taking a logical, user-friendly approach, the systematic name, compound class, structure, natural source, pharmaceutical potential and synthetic routes for each structure are detailed, with clear illustrations throughout, making this book an essential and practical guide for anyone working with both synthesis and natural products. Provides individual outlines for the total synthesis of approximately 100 bioactive natural molecules Outlines each step of the process in detail, with full experimental information supported by extensive schemes Includes retrosynthetic analyses, reaction sequences and stereochemically crucial steps for each molecule

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Author : Anonim
Publisher : Elsevier
Release Date : 2016-06-20
Category : Science
Total pages :470
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Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development. The series covers all aspects of the science, along with the synthesis, testing, and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, the book presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry. Provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures Focuses on the chemistry of bioactive natural products and their exciting new applications in the pharmaceutical industry Presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products Contains contributions by leading authorities in the field

Studies in Natural Products Chemistry

Studies in Natural Products Chemistry
Author : Atta-ur-Rahman
Publisher : Elsevier
Release Date : 2020
Category : Science
Total pages :510
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Studies in Natural Products Chemistry: Bioactive Natural Products (Part XII), Volume 65, is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. Focuses on the chemistry of bioactive natural products Contains contributions by leading authorities in the field Presents sources of new pharmacophores

Bioactive Natural Products (Part B)

Bioactive Natural Products (Part B)
Author : Atta-ur-Rahman
Publisher : Elsevier
Release Date : 2000-03-09
Category : Science
Total pages :826
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Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

Bioactive Natural Products

Bioactive Natural Products
Author : Katherine B. Woods
Publisher : Unknown
Release Date : 2010
Category :
Total pages :129
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Bioactive Natural Products

Bioactive Natural Products
Author : Atta-ur- Rahman
Publisher : Elsevier Science Limited
Release Date : 1988
Category : Science
Total pages :1347
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Cover -- Contents -- Foreword -- Preface -- Contributors -- Chapter 1. Acid-catalysed epimerization of bioactive indole alkaloids and their derivatives -- Chapter 2. Antitumor-promoting and anti-inflammatory activities of triterpenoids and sterols fiom plants and fungi -- Chapter 3. Bioactive oleanene glucuronides obtained from fabaceous plants -- Chapter 4. Biotransformation of terpenoids by microorganisms -- Chapter 5. Cycloartane and oleanane saponins from Astragalus sp. -- Chapter 6. Labdane-type diterpenes: Chemistry and biological activity -- Chapter 7. Metabolism of the tomato saponin a-tomatine by phytopathogenic fungi -- Chapter 8. Heme aggregation inhibitors: Antimalarial drugs targeting an essential biomineralization process -- Chapter 9. Bioactive peptides as signal molecules in plant defense, growth and development -- Chapter 10. Enzymes involved in the biosynthesis of brassinosteroids -- Chapter 11. Immunopotentiating effects of a glycoprotein from Chlorella vulgaris stra ...

Studies in Natural Products Chemistry: Bioactive natural products, pt. A

Studies in Natural Products Chemistry: Bioactive natural products, pt. A
Author : Atta-ur- Rahman
Publisher : Unknown
Release Date : 1988
Category : Natural products
Total pages :129
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Bioactive Natural Products (Part C)

Bioactive Natural Products (Part C)
Author : Atta-ur-Rahman
Publisher : Elsevier Science
Release Date : 2000-11-03
Category : Science
Total pages :826
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Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

Medicinal Chemistry of Bioactive Natural Products

Medicinal Chemistry of Bioactive Natural Products
Author : Xiao-Tian Liang,Wei-Shuo Fang
Publisher : John Wiley & Sons
Release Date : 2006-03-17
Category : Science
Total pages :336
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Current discoveries and research into bioactive naturalproducts Medicinal Chemistry of Bioactive Natural Products provides amuch-needed survey of bioactive natural products and theirapplications in medicinal chemistry. This comprehensive referencefeatures articles by some of the world's leading scientists in thefield on discovery, structure elucidation, and elegant syntheticstrategies--developed for natural products--with an emphasis on thestructure activity relationship of bioactive natural products. Thetopics have been carefully chosen on the basis of relevance tocurrent research and to importance as clinicially usefulagents. Rather than attempting to be a comprehensive encyclopedia ofbioactive natural products, Medicinal Chemistry of BioactiveNatural Products guides the reader to the key developments in thefield. By providing not only practical detail but a historicalperspective on the chemistry and biology of the compounds underconsideration, the book serves as a handy resource for researchersin their own work developing pharmaceuticals, and as an inspiringintroduction for young scientists to the dynamic field of bioactivenatural products research. Enhanced by examples with updated research results, the discussioncovers such topics as: * The chemistry and biology of epothilones * Vancomycin and other glycopeptide antibiotic derivates * Antitumor and other related activities of Taxol and itsanalogs * The antimalarial properties of the traditional Chinese medicine,Quinghaosu (artemisinin) * Huperzine A: A natural drug for the treatment of Alzheimer'sdisease * The medicinal chemistry of ginkgolides from Ginkgo biloba * Recent progress in Calophyllum coumarins as potent anti-HIVagents * Plant-derived anti-HIV agents and analogs * Chemical synthesis of annonaceous acetogenins and theirstructurally modified mimics

Studies in Natural Products Chemistry: Bioactive natural products, pt. F

Studies in Natural Products Chemistry: Bioactive natural products, pt. F
Author : Atta-ur- Rahman
Publisher : Unknown
Release Date : 1988
Category : Natural products
Total pages :129
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