November 28, 2020

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Biomedical Applications of Microfluidic Devices

Biomedical Applications of Microfluidic Devices
Author : Michael R. Hamblin,Mahdi Karimi
Publisher : Academic Press
Release Date : 2020-11-12
Category : Technology & Engineering
Total pages :350
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Biomedical Applications of Microfluidic Devices introduces the subject of microfluidics and covers the basic principles of design and synthesis of actual microchannels. The book then explores how the devices are coupled to signal read-outs and calibrated, including applications of microfluidics in areas such as tissue engineering, organ-on-a-chip devices, pathogen identification, and drug/gene delivery. This book covers high-impact fields (microarrays, organ-on-a-chip, pathogen detection, cancer research, drug delivery systems, gene delivery, and tissue engineering) and shows how microfluidics is playing a key role in these areas, which are big drivers in biomedical engineering research. This book addresses the fundamental concepts and fabrication methods of microfluidic systems for those who want to start working in the area or who want to learn about the latest advances being made. The subjects covered are also an asset to companies working in this field that need to understand the current state-of-the-art. The book is ideal for courses on microfluidics, biosensors, drug targeting, and BioMEMs, and as a reference for PhD students. The book covers the emerging and most promising areas of biomedical applications of microfluidic devices in a single place and offers a vision of the future. Covers basic principles and design of microfluidics devices Explores biomedical applications to areas such as tissue engineering, organ-on-a-chip, pathogen identification, and drug and gene delivery Includes chemical applications in organic and inorganic chemistry Serves as an ideal text for courses on microfluidics, biosensors, drug targeting, and BioMEMs, as well as a reference for PhD students

Microfluidic Devices for Biomedical Applications

Microfluidic Devices for Biomedical Applications
Author : Xiujun James Li,Yu Zhou
Publisher : Elsevier
Release Date : 2013-10-31
Category : Technology & Engineering
Total pages :676
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Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering

Microfluidics for Medical Applications

Microfluidics for Medical Applications
Author : Albert van den Berg,Loes Segerink
Publisher : Royal Society of Chemistry
Release Date : 2014-11-19
Category : Medical
Total pages :328
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Lab-on-a-chip devices for point of care diagnostics have been present in clinics for several years now. Alongside their continual development, research is underway to bring the organs and tissue on-a-chip to the patient, amongst other medical applications of microfluidics. This book provides the reader with a comprehensive review of the latest developments in the application of microfluidics to medicine and is divided into three main sections. The first part of the book discusses the state-of-the-art in organs and tissue on a chip; the second provides a thorough background to microfluidics for medicine, and the third (and largest) section provides numerous examples of point-of-care diagnostics. Written with students and practitioners in mind, and with contributions from the leaders in the field across the globe, this book provides a complete digest of the state-of-the-art in microfluidics medical devices and will provide a handy resource for any laboratory or clinic involved in the development or application of such devices.

Applications of Microfluidic Systems in Biology and Medicine

Applications of Microfluidic Systems in Biology and Medicine
Author : Manabu Tokeshi
Publisher : Springer
Release Date : 2019-04-25
Category : Science
Total pages :382
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This book focuses on state-of-the-art microfluidic research in medical and biological applications. The top-level researchers in this research field explain carefully and clearly what can be done by using microfluidic devices. Beginners in the field —undergraduates, engineers, biologists, medical researchers—will easily learn to understand microfluidic-based medical and biological applications. Because a wide range of topics is summarized here, it also helps experts to learn more about fields outside their own specialties. The book covers many interesting subjects, including cell separation, protein crystallization, single-cell analysis, cell diagnosis, point-of-care testing, immunoassay, embyos/worms on a chip and organ-on-a-chip. Readers will be convinced that microfluidic devices have great potential for medical and biological applications.

Microfluidics and Bio-MEMS

Microfluidics and Bio-MEMS
Author : Tuhin S. Santra
Publisher : CRC Press
Release Date : 2020-11-02
Category : Medical
Total pages :548
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The past two decades have seen rapid development of micro-/nanotechnologies with the integration of chemical engineering, biomedical engineering, chemistry, and life sciences to form bio-MEMS or lab-on-chip devices that help us perform cellular analysis in a complex micro-/nanoflluidic environment with minimum sample consumption and have potential biomedical applications. To date, few books have been published in this field, and researchers are unable to find specialized content. This book compiles cutting-edge research on cell manipulation, separation, and analysis using microfluidics and bio-MEMS devices. It illustrates the use of micro-robots for biomedical applications, vascularized microfluidic organs-on-a-chip and their applications, as well as DNA gene microarray biochips and their applications. In addition, it elaborates on neuronal cell activity in microfluidic compartments, microvasculature and microarray gene patterning, different physical methods for drug delivery and analysis, micro-/nanoparticle preparation and separation in a micro-/nanofluidic environment, and the potential biomedical applications of micro-/nanoparticles. This book can be used by academic researchers, especially those involved in biomicrofluidics and bio-MEMS, and undergraduate- and graduate-level students of bio-MEMS/bio-nanoelectromechanical systems (bio-NEMS), biomicrofluidics, biomicrofabricatios, micro-/nanofluidics, biophysics, single-cell analysis, bionanotechnology, drug delivery systems, and biomedical micro-/nanodevices. Readers can gain knowledge of different aspects of microfluidics and bio-MEMS devices; their design, fabrication, and integration; and biomedical applications. The book will also help biotechnology-based industries, where research and development is ongoing in cell-based analysis, diagnosis, and drug screening.

Microfluidics

Microfluidics
Author : Yujun Song,Daojian Cheng,Liang Zhao
Publisher : John Wiley & Sons
Release Date : 2018-05-07
Category : Science
Total pages :544
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The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.

Microfluidics and BioMEMS Applications

Microfluidics and BioMEMS Applications
Author : Francis E. H. Tay
Publisher : Springer Science & Business Media
Release Date : 2013-04-17
Category : Technology & Engineering
Total pages :336
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Microfluidics and BioMEMS Applications central idea is on microfluidics, a relatively new research field which finds its niche in biomedical devices, especially on lab-on-a-chip and related products. Being the essential component in providing driving fluidic flows, an example of micropump is chosen to illustrate a complete cycle in development of microfluidic devices which include literature review, designing and modelling, fabrication and testing. A few articles are included to demonstrate the idea of tackling this research problem, and they cover the main development scope discussed earlier as well as other advanced modelling schemes for microfluidics and beyond. Scientists and students working in the areas of MEMS and microfluidics will benefit from this book, which may serve both communities as both a reference monograph and a textbook for courses in numerical simulation, and design and development of microfluidic devices.

Microfluidics for Pharmaceutical Applications

Microfluidics for Pharmaceutical Applications
Author : Helder A. Santos,Dongfei Liu,Hongbo Zhang
Publisher : William Andrew
Release Date : 2018-10-12
Category : Science
Total pages :495
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Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications. Presents detailed coverage on the fabrication of novel drug delivery systems with desired characteristics, such as uniform size, Janus particles, and particular or combined responsiveness Includes a variety of case studies that explain principles Focuses on commercialization, cost, safety, society and educational issues of microfluidic applications, showing how microfluidics is used in the real world

Micro/Nano Technology Systems for Biomedical Applications

Micro/Nano Technology Systems for Biomedical Applications
Author : Chih-Ming Ho
Publisher : Oxford University Press
Release Date : 2010-03-25
Category : Mathematics
Total pages :462
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Providing a clear guide that moves from molecules through to devices, this book shows how state-of-the-art micro- and nanotechnologies are already having an impact on human health, and presents the areas of research that will lead to the next generation of micro/nano-based systems for biomedical applications.

Microfluidic Technologies for Human Health

Microfluidic Technologies for Human Health
Author : Ali Khademhosseini,Utkan Demirci,Robert Langer
Publisher : World Scientific
Release Date : 2012
Category : Medical
Total pages :478
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Ch. 1. A microscale bioinspired cochlear-like sensor / Robert D. White, Robert Littrell, and Karl Grosh -- ch. 2. Systematic evaluation of the efficiencies of proteins and chemicals in pharmaceutical applications / Morgan Hamon and Jong Wook Hong -- ch. 3. Microfluidic glucose sensors / Jithesh V. Veetil ... [et al.] -- ch. 4. Applications of microfabrication and microfluidic techniques in mesenchymal stem cell research / Abhijit Majumder ... [et al.] -- ch. 5. Patient-specific modeling of low-density lipoprotein transport in coronary arteries / Ufuk Olgac -- ch. 6. Point-of-care microdevices for global health diagnostics of infectious diseases / Sau Yin Chin ... [et al.] -- ch. 7. Integrated microfluidic sample preparation for chip-based molecular diagnostics / Jane Y. Zhang ... [et al.] -- ch. 8. Microfluidic devices for cellular proteomic studies / Yihong Zhan and Chang Lu -- ch. 9. Microfluidics for neuroscience: novel tools and future implications / Vivian M. Hernandez and P. Hande Ozdinler -- ch. 10. Microfluidics: on-chip platforms as in vitro disease models / Shan Gao, Erkin Seker, and Martin L. Yarmush -- ch. 11. Application of microfluidics in stem cell and tissue engineering / Sasha H. Bakhru, Christopher Highley, and Stefan Zappe -- ch. 12. Microfluidic "on-the-fly" fabrication of microstructures for biomedical applications / Edward Kang, Sau Fung Wong, and Sang-Hoon Lee -- ch. 13. Microfluidics as a promising tool toward distributed viral detection / Elodie Sollier and Dino Di Carlo -- ch. 14. Electrophoresis and dielectrophoresis for lab-on-a-chip (LOC) analyses / Yagmur Demircan, Gurkan Yilmaz, and Haluk Kulah -- ch. 15. Ultrasonic embossing of carbon nanotubes for the fabrication of polymer microfluidic chips for DNA sample purification / Puttachat Khuntontong, Min Gong, and Zhiping Wang -- ch. 16. Ferrofluidics / A. Rezzan Kose and Hur Koser -- ch. 17. Antibody-based blood bioparticle capture and separation using microfluidics for global health / ZhengYuan Luo ... [et al.] -- ch. 18. Applications of quantum dots for fluorescence imaging in biomedical research / ShuQi Wang ... [et al.]

Introduction to BioMEMS

Introduction to BioMEMS
Author : Albert Folch
Publisher : CRC Press
Release Date : 2016-04-19
Category : Medical
Total pages :528
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The entire scope of the BioMEMS field—at your fingertips Helping to educate the new generation of engineers and biologists, Introduction to BioMEMS explains how certain problems in biology and medicine benefit from and often require the miniaturization of devices. The book covers the whole breadth of this dynamic field, including classical microfabrication, microfluidics, tissue engineering, cell-based and noncell-based devices, and implantable systems. It focuses on high-impact, creative work encompassing all the scales of life—from biomolecules to cells, tissues, and organisms. Brilliant color presentation Avoiding the overwhelming details found in many engineering and physics texts, this groundbreaking book—in color throughout—includes only the most essential formulas as well as many noncalculation-based exercises. Important terms are highlighted in bold and defined in a glossary. The text contains more than 400 color figures, most of which are from the original researchers. Coverage of both historical perspectives and the latest developments Developed from the author’s long-running course, this classroom-tested text gives readers a vivid picture of how the field has grown by presenting historical perspectives and a timeline of seminal discoveries. It also describes numerous state-of-the-art biomedical applications that benefit from "going small," including devices that record the electrical activity of brain cells, measure the diffusion of molecules in microfluidic channels, and allow for high-throughput studies of gene expression.

Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications

Micro- and Nanostructured Microfluidic Devices for Localized Protein Immobilization and Other Biomedical Applications
Author : Nicole E Steidle
Publisher : Unknown
Release Date : 2020-10-09
Category : Medical
Total pages :156
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A new immobilization method for the localized adsorption of proteins on thermoplastic surfaces is introduced. Artificial three-phase interfaces were realized by surface structuring to control the wetting behavior which lead to a preferred adsorption in these modified areas. Additionally, different fabrication methods were analyzed to determine mass fabrication capabilities. These fabrication methods also allowed the production of fully structured microchannels to tune the fluids behavior within. This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the work's license are retained by the author or authors.

Microfluidic Devices in Nanotechnology

Microfluidic Devices in Nanotechnology
Author : Challa S. S. R. Kumar
Publisher : John Wiley & Sons
Release Date : 2010-11-29
Category : Technology & Engineering
Total pages :360
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Nanotechnology, especially microfabrication, has been affecting every facet of traditional scientific disciplines. The first book on the application of microfluidic reactors in nanotechnology, Microfluidic Devices in Nanotechnology provides the fundamental aspects and potential applications of microfluidic devices, the physics of microfluids, specific methods of chemical synthesis of nanomaterials, and more. As the first book to discuss the unique properties and capabilities of these nanomaterials in the miniaturization of devices, this text serves as a one-stop resource for nanoscientists interested in microdevices.

Advances in Microfluidics

Advances in Microfluidics
Author : Xiao-Ying Yu
Publisher : BoD – Books on Demand
Release Date : 2016-11-23
Category : Science
Total pages :422
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Increasing innovations and applications make microfluidics a versatile choice for researchers in many disciplines. This book consists of multiple review chapters that aim to cover recent advances and new applications of microfluidics in biology, electronics, energy, and materials sciences. It provides comprehensive views of various aspects of microfluidics ranging from fundamentals of fabrication, flow control, and droplet manipulation to the most recent exploration in emerging areas such as material synthesis, imaging and novel spectroscopy, and marriage with electronics. The chapters have many illustrations showcasing exciting results. This book should be useful for those who are eager to learn more about microfluidics as well as researchers who want to pick up new concepts and developments in this fast-growing field.

3D Printed Microfluidic Devices

3D Printed Microfluidic Devices
Author : Savas Tasoglu,Albert Folch
Publisher : MDPI
Release Date : 2019-01-10
Category :
Total pages :211
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This book is a printed edition of the Special Issue "3D Printed Microfluidic Devices" that was published in Micromachines