January 19, 2021

Download Ebook Free Blanco’s Overview Of Alpha-1 Antitrypsin Deficiency

Blanco's Overview of Alpha-1 Antitrypsin Deficiency

Blanco's Overview of Alpha-1 Antitrypsin Deficiency
Author : Ignacio Blanco
Publisher : Academic Press
Release Date : 2017-04-28
Category : Medical
Total pages :252
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Blanco’s Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels. Presents the fundamental theoretical and practical aspects of Alpha-1 Antitrypsin Deficiency (AATD) based on scientific evidence Provides evidence to show that AATD is a rarely diagnosed condition, rather than a rare condition Contains current research and future perspectives from Dr. Ignacio Blanco, a worldwide expert in the field of alpha-1 antitrypsin and lung and liver disease associated with the deficiency of this antiprotease Provides resources to current registries and patient associations

Rare Diseases Epidemiology: Update and Overview

Rare Diseases Epidemiology: Update and Overview
Author : Manuel Posada de la Paz,Domenica Taruscio,Stephen C. Groft
Publisher : Springer
Release Date : 2017-12-06
Category : Medical
Total pages :667
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The fields of rare diseases research and orphan products development continue to expand with more products in research and development status. In recent years, the role of the patient advocacy groups has evolved into a research partner with the academic research community and the bio-pharmaceutical industry. Unique approaches to research and development require epidemiological data not previously available to assist in protocol study design and patient recruitment for clinical trials required by regulatory agencies prior to approval for access by patents and practicing physicians.

Alpha-1-Antitrypsin Deficiency

Alpha-1-Antitrypsin Deficiency
Author : Pavel Strnad,Mark L. Brantly,Robert Bals
Publisher : European Respiratory Society
Release Date : 2019-09-01
Category : Medical
Total pages :208
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This Monograph offers a comprehensive and up-to-date overview of AATD. It covers basic biology, genetics, laboratory diagnostics and the major organ manifestations; describes the clinical presentation of AATD in both adults and children; and features chapters on genetic counselling, patient views and future therapies. The content has been tailored to meet the needs of the physician, who takes care of lung and liver patients in daily practice, and the general practitioner, who is responsible for the medical guidance of these patients.

Clinical Epidemiology of Chronic Liver Diseases

Clinical Epidemiology of Chronic Liver Diseases
Author : Robert J. Wong,Robert G. Gish
Publisher : Springer
Release Date : 2018-10-24
Category : Medical
Total pages :349
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This book emphasizes the clinical epidemiology of chronic liver diseases with a specific focus on the methodology of the discussed studies. The whole spectrum of liver diseases is covered, from chronic hepatitis B and C, to hepatocellular carcinoma, alcoholic and non-alcoholic fatty liver diseases and autoimmune and cholestatic liver diseases. Readers will find the most up-to-date information on clinical epidemiology of hepatology, and will also be able to learn about important methodology and biostatistics information. Each chapter contains a summary table at the end of each chapter that highlights the most relevant landmark studies, their main outcomes and the unique features of the methodology. The book will appeal to both practicing clinicians as well as clinical research investigators. In addition, this would likely be of interest to medical school or public health school students to learn about hepatology epidemiology, but also some specific fundamentals of clinical research and clinical epidemiology.

Rare and Orphan Lung Diseases, An Issue of Clinics in Chest Medicine, E-Book

Rare and Orphan Lung Diseases, An Issue of Clinics in Chest Medicine, E-Book
Author : Robert Kotloff,Francis X. McCormack
Publisher : Elsevier Health Sciences
Release Date : 2016-08-16
Category : Medical
Total pages :409
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Drs. Robert Kotloff and Francis McCormack have assembled an expert team of authors on the topic of Rare and Orphan Lung Diseases. Articles include: Lymphangioleiomyomatosis, Pulmonary Lymphangiomatosis, Langerhans Cell Histiocytosis and other Histiocytic Diseases of the Lung, Pulmonary Alveolar Proteinosis, Pulmonary Alveolar Microlithiasis, Primary Ciliary Dyskinesia, Birt-Hogg-Dube Syndrome, Hermansky-Pudlak Syndrome, Hereditary Hemorrhagic Telangiectasia, Non-CF Bronchiectasis, Eosinophilic Lung Diseases, Benign Metastasizing Leiomyomata, and more!

Clinical Genetics in Nursing Practice

Clinical Genetics in Nursing Practice
Author : Felissa R. Lashley, PhD, RN, FABMGG
Publisher : Springer Publishing Company
Release Date : 2005-04-15
Category : Medical
Total pages :584
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Designated a Doody's Core Title! The third edition of this award-winning text provides new and updated knowledge about genetics issues relevant to nursing practice. Read in sequence or used as a reference, this is a comprehensive overview of how genetics affetcs the care that nurses provide. In addition to a summary of basic human genetics and discussion of the Human Genome Project, this new edition includes the latest research findings and implications about inheritance, major genetic disorders (cytogenetics or chromosomal, inherited biochemical, and congenital anomalies), and genetics in twin studies. A consideration of the ethical impact of genetics on society and future generations, as well as information on assisted reproduction round out the overview. Includes over 100 illustrations and photos of specific genetic disorders; tables and figures on the distribution of disease; and an extensive appendix listing associations, organizations, and websites relevant to genetics.

COPD, An Issue of Medical Clinics - E-Book

COPD, An Issue of Medical Clinics - E-Book
Author : Stephen I. Rennard,Bartolome R. Celli
Publisher : Elsevier Health Sciences
Release Date : 2012-07-18
Category : Medical
Total pages :223
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This issue of Medical Clinics of North America provides the latest essential updates on COPD. The following topics are covered: pathobiological mechanisms; genes and the disease (alpha-l-antitrypsin); the environment, phenotype, and comorbidity; the role and potential of imaging; pulmonary function and its importance; exercise in testing and therapy; patients’ perception and quality of life; exacerbations, causes, prevention, and treatment; an integrated approach to the medical treatment; meducal pneumoplasty, surgical resection, or lung transplant; and smoking cessation and environmental hygiene.

Abdominal Imaging E-Book

Abdominal Imaging E-Book
Author : Dushyant V Sahani,Anthony E Samir
Publisher : Elsevier Health Sciences
Release Date : 2010-10-29
Category : Medical
Total pages :1600
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Abdominal Imaging, a title in the Expert Radiology Series, edited by Drs. Dushyant Sahani and Anthony Samir, is a comprehensive reference that encompasses both GI and GU radiology. It provides richly illustrated, advanced guidance to help you overcome the full range of diagnostic, therapeutic, and interventional challenges in abdominal imaging and combines an image-rich, easy-to-use format with the greater depth that experienced practitioners need. Select the best imaging approaches and effectively interpret your findings by comparing them to thousands of images that represent every modality and every type of abdominal imaging. Find detailed, expert guidance on all diagnostic, therapeutic, and interventional aspects of abdominal imaging in one authoritative source, including challenging topics such as Oncologic Assessment of Tumor Response and How to Scan a Difficult Patient. Efficiently locate the information you need with a highly templated, well-organized, at-a-glance organization.

Practical Hepatic Pathology: A Diagnostic Approach E-Book

Practical Hepatic Pathology: A Diagnostic Approach E-Book
Author : Romil Saxena
Publisher : Elsevier Health Sciences
Release Date : 2011-02-11
Category : Medical
Total pages :728
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Practical Hepatic Pathology—a new volume in the new Pattern Recognition series—offers you a practical guide to diagnosing every challenging liver biopsy that you encounter in your daily practice. Dr. Romil Saxena presents diagnoses according to a pattern-based organization that guides you from a histological pattern of injury, through the appropriate work-up, around the pitfalls, and to the best diagnosis. Lavish, full-color images capture key hepatic pathology patterns of injury, pathognomonic features and common variations of all major liver diseases and hepatic neoplasms. No other single source delivers the practical, hands-on information you need to solve even the toughest diagnostic challenges in liver biopsies. Recognize the basic patterns of liver injury through an algorithmic approach and establish diagnosis by a pattern-based visual index present at the beginning of the book. Evaluate and interpret biopsy samples using superb, high-quality, full-color images that illustrate pathognomonic features and common variations. Get comprehensive information on major adult and childhood liver diseases, hepatic neoplasms and pre-neoplastic nodules including clinical features, laboratory tests, imaging findings and differential diagnosis. Understand the pathology and practice of liver transplantation with coverage of the clinical aspects of this procedure.

Alpha-1 Antitrypsin

Alpha-1 Antitrypsin
Author : Adam Wanner,Robert A. Sandhaus
Publisher : Humana Press
Release Date : 2015-12-18
Category : Medical
Total pages :173
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This book offers a comprehensive overview of alpha-1 antitrypsin deficiency, an inherited condition that leads to lung disease in adults and liver disease in adults and children and is associated with chronic obstructive lung disease in adults. While it is a rare condition, the mechanisms underlying the clinical manifestations of this deficiency have been largely clarified. Treatment, however, is available only for the lung disease that arises from the condition, thus necessitating continued research into new and alternative therapeutic solutions. The book discusses the biology of alpha-1 antitrypsin, protein misfolding and polymerization, and diagnosis and treatment of alpha-1 antitrypsin deficiency and its associated diseases. It concludes with a discussion of rare disorders linked to alpha-1 antitrypsin deficiency and the role of healthcare organizations in the treatment of these diseases. Written for pulmonary clinicians and scientists, Alpha-1 Antitrypsin: Role in Health and Disease is a valuable resource that sheds light on this rare disease.

Muscle Gene Therapy

Muscle Gene Therapy
Author : Dongsheng Duan
Publisher : Springer Science & Business Media
Release Date : 2009-11-26
Category : Medical
Total pages :275
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Muscle disease represents an important health threat to the general population. There is essentially no cure. Gene therapy holds great promise to correct the genetic defects and eventually achieve full recovery in these diseases. Significant progresses have been made in the field of muscle gene therapy over the last few years. The development of novel gene delivery vectors has substantially enhanced specificity and efficiency of muscle gene delivery. The new knowledge on the immune response to viral vectors has added new insight in overcoming the immune obstacles. Most importantly, the field has finally moved from small experimental animal models to human patients. This book will bring together the leaders in the field of muscle gene transfer to provide an updated overview on the progress of muscle gene therapy. It will also highlight important clinical applications of muscle gene therapy.

The Lancet

The Lancet
Author : Anonim
Publisher : Unknown
Release Date : 2005
Category : Medicine
Total pages :129
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The Journal of Rheumatology

The Journal of Rheumatology
Author : Anonim
Publisher : Unknown
Release Date : 2004
Category : Arthritis
Total pages :129
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Molecular Pathology of Liver Diseases

Molecular Pathology of Liver Diseases
Author : Satdarshan P. S. Monga
Publisher : Springer Science & Business Media
Release Date : 2010-12-14
Category : Medical
Total pages :931
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Cellular and Molecular Pathology of the Liver is extensive, complex and ranges from the understanding the basic molecular mechanisms that dictate everything from liver homeostasis to liver disease. Molecular Pathology of the liver is complicated due to some of the important functions inherent and unique to the Liver, including its innate ability to regenerate and the multitude of functions it plays for the wellbeing of an organism. With all this in mind, Molecular Pathology of Liver Diseases is organized in different sections, which will coherently and cohesively present the molecular basis of hepatic physiology and pathology. The first two sections are key to understanding the liver anatomy and physiology at a cellular level and go on to define the molecular mechanics in various liver cell types. These sections also cover the existing paradigms in liver development, regeneration and growth. The next section is key to understanding the Molecular Pathology unique to liver diseases and associated phenotypes. The final sections are geared towards the existing knowledge of the molecular basis of many common and uncommon liver diseases in both neoplastic and non-neoplastic areas including pathologies associated with intra-hepatic and extra-hepatic biliary tree. Thus, this textbook is a one-stop reference for comprehending the molecular mechanisms of hepatic pathobiology. It is clearly unique in its format, readability and information and thus will be an asset to many in the field of Pathology and other disciplines.

Alpha-1-Antitrypsin Deficiency

Alpha-1-Antitrypsin Deficiency
Author : Florie Borel,Christian Mueller
Publisher : Humana Press
Release Date : 2017-08-08
Category : Science
Total pages :278
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This volume provides protocols that expand on the latest alpha-1-antitrypsin (AAT) research. The chapters in this book are divided in to three sections: Part I is dedicated to patient-oriented research; part II discusses animal models; and Part III focuses on in vitro studies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and authoritative, Alpha-1 Antitrypsin Deficiency: Methods and Protocols is a valuable resource for researchers, students, and clinican-scientists interested in AAT deficiency, as well as anyone working in the fields of pulmonology and hepatology.