June 17, 2021

Download Ebook Free Capillary Electromigration Separation Methods

Capillary Electromigration Separation Methods

Capillary Electromigration Separation Methods
Author : Colin F. Poole
Publisher : Elsevier
Release Date : 2018-04-13
Category : Science
Total pages :626
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Capillary Electromigration Separation Methods is a thorough, encompassing reference that not only defines the concept of contemporary practice, but also demonstrates its implementation in laboratory science. Chapters are authored by recognized experts in the field, ensuring that the content reflects the latest developments in research. Thorough, comprehensive coverage makes this the ideal reference for project planning, and extensive selected referencing facilitates identification of key information. The book defines the concept of contemporary practice in capillary electromigration separation methods, also discussing its applications in small mass ions, stereoisomers, and proteins. Edited and authored by world-leading capillary electrophoresis experts Presents comprehensive coverage on the subject Includes extensive referencing that facilitates the identification of key research developments Provides more than 50 figures and tables that aid in the retention of key concepts

Analytical Separation Science, 5 Volume Set

Analytical Separation Science, 5 Volume Set
Author : Jared Anderson,Alain Berthod,Veronica Pino,Apryll M. Stalcup
Publisher : Wiley-VCH
Release Date : 2016-02-29
Category : Science
Total pages :2220
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Leading the way for analytical chemists developing new techniques. This new comprehensive 5 volume set on separation science provides a much needed research-level text for both academic users and researchers who are working with and developing the most current methods, as well as serving as a valuable resource for graduate and post-graduate students. Comprising of five topical volumes it provides a comprehensive overview of the subject, highlighting aspects that will drive research in this field in the years to come. Volume 1: Liquid Chromatography Volume 2: Special Liquid Chromatography Modes and Capillary Electromigration Techniques Volume 3: Gas, Supercritical and Chiral Chromatography Volume 4: Chromatographic and Related Techniques Volume 5: Sample Treatment, Method Validation, and Applications Key Features: - Comprises over 2,100 pages in 5 volumes – available in print and online - Edited by an international editorial team which has both prominent and experienced senior researchers as well as young and dynamic rising stars - Individual chapters are labeled as either introductory or advanced, in order to guide readers in finding the content at the appropriate level - Fully indexed with cross referencing within and between all 5 volumes

Fundamental Aspects and Biochemical Applications of Capillary Electromigration Methods

Fundamental Aspects and Biochemical Applications of Capillary Electromigration Methods
Author : Jinping Liu
Publisher : Unknown
Release Date : 1991
Category :
Total pages :696
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The Essence of Chromatography

The Essence of Chromatography
Author : C. F. Poole
Publisher : Elsevier
Release Date : 2003
Category : Science
Total pages :925
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The Essence of Chromatography presents a comprehensive survey of modern chromatography and is intended as a suitable text for graduate level courses in the separation sciences and as a self-study guide for professional chromatographers wishing to refresh their background in this rapidly expanding field. This title is an effective replacement for Chromatography Today, written by the same author with Salwa K. Poole, which is considered to be one of the definitive chromatographic texts of the last decade. Its format is modular, with extensive cross-references to permit rapid location of related material using different separation concepts. Important features are extensive tabulation of essential data for performing separations and an extensive bibliography to the most recent literature. · Comprehensive and authoritative coverage of chromatographic techniques · Contains extensive coverage of recent literature on this subject · Ideal text for graduates and suitable for professional chromatographers

Handbook of HPLC

Handbook of HPLC
Author : Danilo Corradini
Publisher : CRC Press
Release Date : 2020-07-02
Category :
Total pages :720
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High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the publication of the benchmark first edition twelve years ago. It reports detailed information on fundamental and practical aspects of HPLC related to conventional format and sophisticated novel approaches which have been developed to address a variety of separation problems in different fields. The latest concepts New concepts presented in this edition include monolithic columns, bonded stationary phases, micro-HPLC, two-dimensional comprehensive liquid chromatography, gradient elution mode, and capillary electromigration techniques. The book also discusses LC-MS interfaces, nonlinear chromatography, displacement chromatography of peptides and proteins, field-flow fractionation, retention models for ions, and polymer HPLC. Fundamentals and applications The first section of the book explores emerging novel aspects of HPLC and related separation methods based on the differential velocity of analytes in a liquid medium under the action of either an electric field (capillary electromigration techniques) or a gravitational field (field-flow fractionation). The section focusing on applications highlights four significant areas in which HPLC is successfully employed: chiral pharmaceutical, environmental analysis, food analysis, and forensic science. Ideal for a widespread audience Explanatory figures and tables supplement the text and clarify difficult concepts. Extensive references provide gateways to more focused study. Suitable for undergraduates or new practitioners interested in improving their knowledge on the current status and future trends of HPLC, the book is also a critical resource for researchers looking for solutions to complex separation problems or those who currently use HPLC either as an analytical or a preparative scale tool.

Analytical Separation Science

Analytical Separation Science
Author : Jared Anderson,Alain Berthod,Veronica Pino,Apryll M. Stalcup
Publisher : John Wiley & Sons
Release Date : 2016-02-08
Category : Science
Total pages :2220
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Leading the way for analytical chemists developing new techniques. Introductory Price Available! Order your print copy before 30th April 2016 and save! £650 / $1,075 / €799 List price thereafter: £735 / $1,210 / €899 This new comprehensive 5 volume set on separation science provides a much needed research-level text for both academic users and researchers who are working with and developing the most current methods, as well as serving as a valuable resource for graduate and post-graduate students. Comprising of five topical volumes it provides a comprehensive overview of the subject, highlighting aspects that will drive research in this field in the years to come. Volume 1: Liquid Chromatography Volume 2: Special Liquid Chromatography Modes and Capillary Electromigration Techniques Volume 3: Gas, Supercritical and Chiral Chromatography Volume 4: Chromatographic and Related Techniques Volume 5: Sample Treatment, Method Validation, and Applications Key Features: - Comprises over 2,100 pages in 5 volumes – available in print and online - Edited by an international editorial team which has both prominent and experienced senior researchers as well as young and dynamic rising stars - Individual chapters are labeled as either introductory or advanced, in order to guide readers in finding the content at the appropriate level - Fully indexed with cross referencing within and between all 5 volumes

Quality Control in Pharmaceutical Analysis

Quality Control in Pharmaceutical Analysis
Author : Z. Deyl
Publisher : Elsevier Science Limited
Release Date : 1997-01-01
Category : Science
Total pages :241
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It is difficult, if not impossible, to visualize pharmaceutical industry processes without appropriate analytical control, of which chromatographic and, more recently, capillary electromigration techniques constitute a considerable proportion. Problems such as deciding which separation technique will be the best, whether a chromatographic or an electrokinetically driven method is preferred, calibration procedures and method validation, identification of impurities by on-line hyphenation with techniques based on physicochemical principles other than chromatography and electrophoresis and assaying of basic physicochemical properties are all to be solved by the analytical chemist. Unintended errors can occur quite frequently. This volume covers all the above outlined areas, emphasizing those which the authors know from pharmaceutical research to cause problems in practice. The basic guidelines have been summarized along with the necessary theoretical background to help analysts select and apply modern chromatographic and electrokinetic methods of analysis in drug production and quality control and help them solve their particular problems.

16th International Symposium on Separation Sciences

16th International Symposium on Separation Sciences
Author : Danilo Corradini
Publisher : Unknown
Release Date : 2011
Category :
Total pages :174
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Use of non-specific and specific interactions in the analysis of testosterone and related compounds by capillary electromigration techniques

Use of non-specific and specific interactions in the analysis of testosterone and related compounds by capillary electromigration techniques
Author : Lotta K. Amundsen
Publisher : Unknown
Release Date : 2008
Category : Testosterone
Total pages :129
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Determination of testosterone and related compounds in body fluids is of utmost importance in doping control and the diagnosis of many diseases. Capillary electromigration techniques are a relatively new approach for steroid research. Owing to their electrical neutrality, however, separation of steroids by capillary electromigration techniques requires the use of charged electrolyte additives that interact with the steroids either specifically or non-specifically. The analysis of testosterone and related steroids by non-specific micellar electrokinetic chromatography (MEKC) was investigated in this study. The partial filling (PF) technique was employed, being suitable for detection by both ultraviolet spectrophotometry (UV) and electrospray ionization mass spectrometry (ESI-MS). Efficient, quantitative PF-MEKC-UV methods for steroid standards were developed through the use of optimized pseudostationary phases comprising surfactants and cyclodextrins. PF-MEKC-UV proved to be a more sensitive, efficient and repeatable method for the steroids than PF-MEKC-ESI-MS. We discovered that in PF-MEKC analyses of electrically neutral steroids, ESI-MS interfacing sets significant limitations not only on the chemistry affecting the ionization and detection processes, but also on the separation. The new PF-MEKC-UV method was successfully employed in the determination of testosterone in male urine samples after microscale immunoaffinity solid-phase extraction (IA-SPE). The IA-SPE method, relying on specific interactions between testosterone and a recombinant anti-testosterone Fab fragment, is the first such method described for testosterone. Finally, new data for interactions between steroids and human and bovine serum albumins were obtained through the use of affinity capillary electrophoresis. A new algorithm for the calculation of association constants between proteins and neutral ligands is introduced.

Handbook of HPLC

Handbook of HPLC
Author : Danilo Corradini
Publisher : CRC Press
Release Date : 2016-04-19
Category : Science
Total pages :715
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High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the

Journal of Capillary Electrophoresis

Journal of Capillary Electrophoresis
Author : Anonim
Publisher : Unknown
Release Date : 2004
Category : Capillary electrophoresis
Total pages :129
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Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis

Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis
Author : Peter Mikuš
Publisher : BoD – Books on Demand
Release Date : 2012-08-29
Category : Medical
Total pages :210
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The scientific monograph by the author Peter Mikus entitled "Chiral Capillary Electrophoresis in Current Pharmaceutical and Biomedical Analysis" provides a comprehensive view on the advanced capillary electrophoresis techniques aimed to current chiral bioanalysis. The advances in the chiral electrophoresis analytical approaches are divided and theoretically described in three sections involving (i) advanced chiral separations for the optimization of chiral resolution (separation mechanisms; electrophoresis techniques in capillary and microchip format; electrophoretic modes such as ITP, CZE/EKC, CEC; chiral additives / pseudophases / phases), (ii) advanced sample preparation for the on-line preconcentration, sample clean-up and analyte derivatization (implementation of electrophoretic effects such as stacking; non-electrophoretic effects such as SPE, chromatography, dialysis; combinations of these effects; multidimensional CE systems; instrumental schemes), (iii) advanced combinations of detection and electrophoresis for the optimization in qualitative and quantitative evaluation (the most important universal as well as selective detection approaches such as absorption and fluorescence spectrophotometry, electrochemical detection, mass spectrometry vs. (i) and/or (ii)). Real analytical potential (benefits and limitations) of these advanced analytical approaches is emphasized by selected performance parameters of the methods and illustrated by many current practical applications including chiral analyses of drugs, their (bio)degradation products and biomarkers in pharmaceutical and biological matrices. The author wishes the readers many inspirations in the creation of new innovative approaches in the field of advanced chiral electrophoresis techniques with the aim to overcome capabilities of the current analytical techniques.

Modified Cyclodextrins for Chiral Separation

Modified Cyclodextrins for Chiral Separation
Author : Weihua Tang,Siu-Choon Ng,Dongping Sun
Publisher : Springer Science & Business Media
Release Date : 2013-05-24
Category : Science
Total pages :258
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Modified Cyclodextrins for Chiral Separation offers a review of the latest advances in developing modified cyclodextrins as chiral selectors for various chromatographic and electromigration techniques. Over the years, many descriptions of chiral separation have appeared in academic journals and books, but most of them have been devoted to either the development of analytical methods and protocols or the summary of different chiral selectors, including cyclodextrins for chiral separation applications. This is in marked contrast to this volume which focuses on the research endeavors concerning the development of cyclodextrin derivatives specifically as either chiral mobile phases for capillary electrophoresis, or chiral stationary phases for various chromatographic techniques including gas chromatography, or high-performance liquid chromatography and supercritical fluid chromatography. The ongoing thread in this book is the synthesis of structurally-defined cyclodextrin derivatives and their applications in enantiomer separation by means of different analytical techniques. Modified Cyclodextrins for Chiral Separation is intended for those who are interested in expanding their knowledge of cyclodextrin chemistry and chiral separation, and in what cyclodextrin modification can be made to suit the needs of chiral selectors for different analytical techniques. It primarily focuses on the state-of-the-art cyclodextrin chemistry which is the basis for all chiral selectors used in these chiral separation techniques. Weihua Tang, PhD, is a professor at the Key Laboratory of Soft Chemistry and Functional Materials, Ministry of Education, Nanjing University of Science and Technology, China. Siu-Choon Ng, PhD, is a professor at the Division of Chemical and Biomedical Engineering, School of Chemical and Biomedical Engineering, Nanyang Technological University, Singapore. Dongping Sun, PhD, is a professor at the Key Laboratory of Soft Chemistry and Functional Materials, Ministry of Education, Nanjing University of Science and Technology, China.