December 5, 2020

Download Ebook Free Chinmedomics

Chinmedomics

Chinmedomics
Author : Xijun Wang,Aihua Zhang,Hui Sun
Publisher : Academic Press
Release Date : 2015-07-15
Category : Medical
Total pages :408
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Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications Edited by the leading experts of research related to Chinmedomics

Systems Thinking in Medicine and New Drug Discovery

Systems Thinking in Medicine and New Drug Discovery
Author : Robert E. Smith
Publisher : Cambridge Scholars Publishing
Release Date : 2018-12-17
Category : Medical
Total pages :632
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Total Quality Management (TQM) and systems thinking are being used to improve all aspects of human health. This first book in a two-volume set details how the healthcare community is working with patients and their caregivers to improve healthcare and reduce its costs. Systems-based thinking encourages us to work together to look at the effects of new drugs on entire systems and not just single molecular targets. It also leads us to a better understanding of genetics and epigenetics, as well as the deep ecology of the human body. The healthcare community is developing targeted therapies that stimulate our own bodies to cure ourselves and eliminate the need for animal testing. This book will appeal to specialists, who will find recommendations on safer materials for 3D bioprinting and ways to analyze dietary supplements for toxic contaminants, and physicians, pharmacists and non-professionals, who will learn the important different ways that dietary supplements and prescription drugs are developed, sold and marketed.

Serum Pharmacochemistry of Traditional Chinese Medicine

Serum Pharmacochemistry of Traditional Chinese Medicine
Author : Xijun Wang,Aihua Zhang,Hui Sun
Publisher : Academic Press
Release Date : 2016-12-27
Category : Medical
Total pages :378
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Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development. Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications Edited and written by leading scientists at the forefront of this research Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature

Pharmaceuticals to Nutraceuticals

Pharmaceuticals to Nutraceuticals
Author : Dilip Ghosh,R. B. Smarta
Publisher : CRC Press
Release Date : 2016-10-26
Category : Medical
Total pages :266
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Recently, there has been a fundamental shift in the global health and wellness industry from disease treatment to preventing chronic diseases. The use of nutraceuticals and functional foods in prevention efforts could lead to a decreased dependency on drugs. The pharmaceutical industry recognizes this shift; however, serious concerns have arisen regarding the claimed efficacy, quality, and safety of products used as medical foods. This book examines the consumer and industry mindshift, including the scientific evidence of these foods as effective adjuncts to pharmacotherapy during all stages of treatment of various diseases, thus indicating that pharmaceuticals and nutraceuticals can and should coexist. It details quality, safety, and efficacy of foods, drugs, and nutrients; marketing and product positioning; regulatory perspectives; biomarkers and metabolites; probiotics; food/drug interactions; and future industry trends. In addition, food bioactives represent diet-based molecules that perform physiological roles related to disease prevention and treatment. As such, a considerable overlap exists between food bioactives and drugs—this book presents the case for comparing and contrasting foods versus drugs in several models of health and disease.

Pharmacological Advances in Natural Product Drug Discovery

Pharmacological Advances in Natural Product Drug Discovery
Author : Guanhua Du
Publisher : Academic Press
Release Date : 2020-03
Category :
Total pages :312
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Pharmacological Advances in Natural Product Drug Discovery, Volume 87 in the Advances in Pharmacology series, presents the latest pharmacological research progresses of 8 medicinal compounds from natural products, including salvianolic acid, tanshinone, paeonol, chlorogenic acid, astragaloside, icariin, ganoderan, and febrifugine. Specific chapters to this new release include Potential Role of Paeonol on Atherosclerosis Related Cells, A Review on Salvianolic Acid, Pharmacological Advances of Tanshinones, the Natural Product of Salvia Miltiorrhiza, Pharmacological Action and Potential Targets Analysis of Major Pharmacological Effects of Chlorogenic Acid, Modern TCM: Identifying and Defining the "Medicinal Mix", Pharmacological Advances in Astragaloside IV Derived from Astragalus Membranaceus, and much more. Includes the authority and expertise of leading contributors in natural product pharmacology Provides the latest pharmacological research progresses of eight medicinal compounds from natural products Presents a thorough discussion on the compatibility of traditional medicines

Systems Biology and Its Application in TCM Formulas Research

Systems Biology and Its Application in TCM Formulas Research
Author : Wei-Dong Zhang
Publisher : Academic Press
Release Date : 2018-02-16
Category : Medical
Total pages :380
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Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine. Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research

Japanese Kampo Medicines for the Treatment of Common Diseases

Japanese Kampo Medicines for the Treatment of Common Diseases
Author : Somasundaram Arumugam,Kenichi Watanabe
Publisher : Academic Press
Release Date : 2017-03-17
Category : Medical
Total pages :222
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Japanese Kampo Medicines for the Treatment of Common Diseases - Focus on Inflammation provides researchers and clinicians with a current look at how Kampo medicines can be used to effectively treat inflammatory disorders. Japanese Kampo medicines are a mixture of natural and herbal medicines that are available in Japan for the treatment of various diseases. Given their therapeutic potential, they are often prescribed instead of, or alongside, allopathic medicines. Kampo medicines are becoming more widespread and have proven effective for the treatment of a variety of inflammatory diseases, such as colitis, dermatitis, myocarditis, hepatitis, cardiomyopathy, and nephritis. This book offers background on Japanese Kampo medicines, along with a compilation of the published scientific data for several different types of Kampo medicines. It is an evidence-based guide for all those involved in, or interested in, the research and practice of Kampo medicine. Includes both preclinical and clinical data published from a variety of sources and compiled into one book Provides insight for researchers and clinicians on which Kampo medicines will provide the least side effects and offer the most effective therapy for a particular illness Offers important data that will help to inform future research and widen practice in this area

Shengmai San

Shengmai San
Author : Robert Kam-Ming Ko
Publisher : CRC Press
Release Date : 2002-06-20
Category : Health & Fitness
Total pages :160
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Traditional Chinese medicine commonly prescribes herbal formulas for the prevention and treatment of diseases. Shengmai San, a famous Chinese medicinal formula that has been used for more than eight hundred years in China, is comprised of Radix Ginseng, Fructus Schisandre and Radix Ophiopogonis. Traditionally, Shengmai San is used for the treatment

Personalized Cancer Chemotherapy

Personalized Cancer Chemotherapy
Author : Da Yong Lu
Publisher : Woodhead Publishing
Release Date : 2014-12-05
Category : Medical
Total pages :84
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Personalized Cancer Chemotherapy separately describes and addresses "individualized cancer chemotherapy" (ICC) strategies new and old, to provide readers with new insights into their characteristics and techniques, as well as key debates and future trends in this area. The book devotes chapters to drug sensitivity testing, cancer biomarkers and bioinformatics detection, pharmacogenetics, individualized antimetastatic therapy, drug combinations, assistant chemotherapy, and cost-effectiveness considerations. A major obstacle to controlling cancer growth and metastases in patients is the inappropriate use of anticancer and antimetastatic drugs. Researchers and clinicians are now beginning to focus on ICC also called "personalized cancer chemotherapy" (PCC), to improve therapeutic quality and outcomes by selecting and prescribing the most appropriate and effective drugs. Using genetic, molecular, and bioinformatics data and modern experimental techniques, known tumor genes can be detected more easily than ever before; the average speed of genetic sequencing has increased 15,000 to 50,000 times since the Human Geonme Project was completed. This book will help readers understand the pros and cons of each individualized cancer chemotherapy strategy from different angles so as to make good judgments and predictions of drug responses and clinical outcomes. Explores the central components of cancer treatment Investigates new developments in cancer treatment Discusses the many strategies of individualized cancer chemotherapy

Toxicology of Herbal Products

Toxicology of Herbal Products
Author : Olavi Pelkonen,Pierre Duez,Pia Maarit Vuorela,Heikki Vuorela
Publisher : Springer
Release Date : 2017-03-07
Category : Medical
Total pages :479
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This volume provides a comprehensive overview of the hazards inherent in herbal medicinal products, with systematic coverage of major toxicities. Topics include composition and quality control, toxicokinetics, interactions, safety pharmacology, approaches to studying complex mixtures including metabolomics and systems network pharmacology, and long-term toxicity. The volume also discusses various organ toxicities with a special emphasis on basic mechanisms of actions and the multicomponent and multi-target nature of herbal products. It concludes with a look to future challenges and opportunities. With contributions from noted experts, Toxicology of Herbal Products is a necessary resource for physicians, pharmacists, and toxicologists interested in complex plant-derived products.

Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine

Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine
Author : Anika Niambi Al-Shura
Publisher : Academic Press
Release Date : 2019-10-16
Category : Science
Total pages :228
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Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine, the first volume in the Integrative Cardiovascular Chinese Medicine series, provides a comprehensive guide to improving outcomes with cardiovascular medicine therapy options. Coverage includes the three types of medicines used in disease stage treatment, Chinese medicine, nutritional supplements and pharmaceutical drugs. All sections are organized according to drug class in western medicine and chapters in each section are organized according to disease stage, providing ease in navigation and reference within the book. This important reference will aid cardiovascular researchers in the study of integrative Chinese and western medicine as well as provide a clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners. Integrates Western and Chinese Medicine for a realistic and complete scope of cardiology treatment, establishing the basis for standardization and rationale of inclusion of Traditional Chinese Medicine in cardiology Presents a structure for prescribing herbal formulas and nutritional supplements with or without pharmaceutical drugs Examines diet and lifestyle according to constitution in Traditional Chinese Medicine to prevent the progression of disease and/or maintain health before or after chronic stages

Integrative Medicine for Children

Integrative Medicine for Children
Author : May Loo
Publisher : Elsevier Health Sciences
Release Date : 2009
Category : Health & Fitness
Total pages :522
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"Fifty-five common pediatric conditions are comprehensively discussed, with diagnostic and evidence-based treatment information, followed by authoritative information on the major CAM therapies available for treatment of the condition. Whenever possible, an integrative approach that combines conventional and alternative approaches is presented."--BOOK JACKET.

High-Throughput Metabolomics

High-Throughput Metabolomics
Author : Angelo D'Alessandro
Publisher : Humana
Release Date : 2020-06-06
Category : Science
Total pages :459
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This detailed volume focuses on recent technological, computational, and biostatistical advances in the field of high-throughput metabolomics. Chapters encompass methods, platforms, and analytical strategies for steady state measurements and metabolic flux analysis with stable isotope-labeled tracers, in biological matrices of clinical relevance and model organisms. Mass spectrometry-based or orthogonal methods are discussed, along with computational and statistical methods to address data sparsity in high-throughput metabolomics approaches. As a part of the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High-Throughput Metabolomics: Methods and Protocols provides tools that can bring about the next generation of clinical biochemistry in a cost-effective, rigorous fashion, exponentially advancing our capacity to investigate nature while hastening the advent of personalized medicine.

Herbal Medicines

Herbal Medicines
Author : Aiko Inui
Publisher : Humana Press
Release Date : 2016-09-22
Category : Medical
Total pages :264
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This book examines the use of herbal medicine in the treatment of intractable diseases as well as common health problems. Given the stringent quality control of herbal medicine such as Kampo and reproducibility of preclinical findings, together with overall fewer adverse events, its attractiveness continues to rise, and multi-component herbal medicine capable of targeting multiple sites can be useful for future drug discovery. Written for the Methods in Pharmacology and Toxicology series, this collection features practical advice for hands-on work in this exciting and expansive field. Authoritative and easily applicable, Herbal Medicines: New Horizons summarizes the current state and translational aspect of herbal medicine in modern society in order to help establish a rational therapy for patients.

Ranunculales Medicinal Plants

Ranunculales Medicinal Plants
Author : Da-Cheng Hao
Publisher : Academic Press
Release Date : 2018-04-23
Category : Medical
Total pages :404
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Ranunculales Medicinal Plants: Biodiversity, Chemodiversity and Pharmacotherapy comprehensively covers this order of flowering plants, detailing the phytochemistry, chemotaxonomy, molecular biology, and phylogeny of selected medicinal plants families and genera and their relevance to drug efficacy. The book carries out an exhaustive survey of the literature in order to characterize global trends in the application of flexible technologies. The interrelationship between Chinese species, and between Chinese and non-Chinese species, is inferred through molecular phylogeny and based on nuclear and chloroplast DNA sequencing. The book discusses the conflict between chemotaxonomy and molecular phylogeny in the context of drug discovery and development. Users will find invaluable and holistic coverage on the study of Ranunculales that will make this the go-to pharmaceutical resource. Describes current perceptions of biodiversity and chemodiversity of Ranunculales Explains how the conceptual framework of plant pharmacophylogeny benefits the sustainable exploitation of Ranunculales Details how Ranunculales medicinal plants work from the chemical level upward Covers how the polypharmacology of Ranunculales compounds might inspire new chemical entity design and development for improved treatment outcomes