November 24, 2020

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Chronic Pain and Brain Abnormalities

Chronic Pain and Brain Abnormalities
Author : Carl Y. Saab
Publisher : Academic Press
Release Date : 2013-06-28
Category : Medical
Total pages :176
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It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. Philosophical and social concepts of pain; testimonials of chronic-pain patients Clinical data from pain patients’ brains Advances in noninvasive brain imaging for pain patients Combining theoretical and empirical approaches to the analysis of pain-related brain function Manipulation of brain function in animal models Emerging neurotechnology principles for pain diagnostics and therapeutics

Chronic Pain and Brain Abnormalities

Chronic Pain and Brain Abnormalities
Author : Carl Y. Saab
Publisher : Academic Press
Release Date : 2013-06-28
Category : Medical
Total pages :176
GET BOOK

It is only natural for someone in pain to attend to the body part that hurts. Yet this book tells the story of persistent pain having negative effects on brain function. The contributors, all leading experts in their respective fields of pain electrophysiology, brain imaging, and animal models of pain, strive to synthesize compelling and, in some ways, connected hypotheses with regard to pain-related changes in the brain. Together, they contribute their clinical, academic, and theoretical expertise in a comprehensive overview that attempts to define the broader philosophical context of pain (disentangling sensical from nonsensical claims), list the changes known to take place in the brains of individuals with chronic pain and animal models of pain, address the possible causes and mechanisms underlying these changes, and detail the techniques and analytical methods at our disposal to "visualize" and study these changes. Philosophical and social concepts of pain; testimonials of chronic-pain patients Clinical data from pain patients’ brains Advances in noninvasive brain imaging for pain patients Combining theoretical and empirical approaches to the analysis of pain-related brain function Manipulation of brain function in animal models Emerging neurotechnology principles for pain diagnostics and therapeutics

Translational Pain Research

Translational Pain Research
Author : Lawrence Kruger,Alan R Light
Publisher : CRC Press
Release Date : 2009-11-24
Category : Health & Fitness
Total pages :432
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One of the Most Rapidly Advancing Fields in Modern Neuroscience The success of molecular biology and the new tools derived from molecular genetics have revolutionized pain research and its translation to therapeutic effectiveness. Bringing together recent advances in modern neuroscience regarding genetic studies in mice and humans and the practicality of clinical trials, Translational Pain Research: From Mouse to Man effectively bridges the gap between basic research and patient care by humanely examining rodent models for pain associated with bone cancer, osteoarthritis, fibromyalgia, and cardiac episodes. Distinguished Team of International Contributors In addition to addressing the groundbreaking technical advances in tract tracing, endocannabinoids, cannabis, gene therapy, siRNA gene studies, and the role of glia, cytokines, P2X receptors and ATP, this book also presents cutting-edge information on: Nociceptor sensitization Muscle nociceptors and metabolite detection Visceral afferents in disease Innovative rodent model for bone cancer pain Highly specific receptor cloning Modular molecular mechanisms relevant to painful neuropathies This sharply focused work also discusses unexpected discoveries derived from brain-imaging studies related to thalamic pain. Translational Pain Research covers the progress made toward bringing laboratory science (much of it at the molecular level) to our understanding of pain phenomena in humans, with the ultimate goal of reducing the suffering that often accompanies pain and its indirect consequences.

Motivational Perspectives on Chronic Pain

Motivational Perspectives on Chronic Pain
Author : Paul Karoly,Geert Crombez
Publisher : Oxford University Press
Release Date : 2018-08-07
Category : Psychology
Total pages :552
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Motivational Perspectives on Chronic Pain is one of the first volumes to present a cohesive account of the adaptation to chronic pain from a motivational perspective. Contributing authors from diverse areas of pain research offer comprehensive summaries of the concepts, findings, and applied methodologies that converge on the role of goals and goal-related cognitive processes, self-regulatory support mechanisms, contextual forces, and emotionality as they influence (and are influenced by) the experience of chronic pain. This volume provides readers with an up-to-date compendium of cutting-edge research and interventions that collectively illustrate the utility of viewing chronic pain neither as a "disease" nor an imposed lifestyle, but as the emergent and potentially flexible product of a complex transactional system that is bounded by both sociocultural factors and by biogenetic and neural moderating forces. Within its pages, chapters capture the vibrancy of current theory, research, and practice while pointing toward unexplored new directions. Among the important topics addressed by this distinguished group of authors include: the nature and relevance of control systems, the role of neural mechanisms on pain processing, the influence positive and negative emotion regulation play on pain management, the impact of learning and conditioning, and the often neglected influence of interpersonal processes on adjustment to chronic pain.

Relieving Pain in America

Relieving Pain in America
Author : Institute of Medicine,Board on Health Sciences Policy,Committee on Advancing Pain Research, Care, and Education
Publisher : National Academies Press
Release Date : 2011-10-26
Category : Medical
Total pages :382
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Chronic pain costs the nation up to $635 billion each year in medical treatment and lost productivity. The 2010 Patient Protection and Affordable Care Act required the Department of Health and Human Services (HHS) to enlist the Institute of Medicine (IOM) in examining pain as a public health problem. In this report, the IOM offers a blueprint for action in transforming prevention, care, education, and research, with the goal of providing relief for people with pain in America. To reach the vast multitude of people with various types of pain, the nation must adopt a population-level prevention and management strategy. The IOM recommends that HHS develop a comprehensive plan with specific goals, actions, and timeframes. Better data are needed to help shape efforts, especially on the groups of people currently underdiagnosed and undertreated, and the IOM encourages federal and state agencies and private organizations to accelerate the collection of data on pain incidence, prevalence, and treatments. Because pain varies from patient to patient, healthcare providers should increasingly aim at tailoring pain care to each person's experience, and self-management of pain should be promoted. In addition, because there are major gaps in knowledge about pain across health care and society alike, the IOM recommends that federal agencies and other stakeholders redesign education programs to bridge these gaps. Pain is a major driver for visits to physicians, a major reason for taking medications, a major cause of disability, and a key factor in quality of life and productivity. Given the burden of pain in human lives, dollars, and social consequences, relieving pain should be a national priority.

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders
Author : Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
Publisher : Elsevier
Release Date : 2014-12-03
Category : Science
Total pages :824
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Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Foundations for Osteopathic Medicine

Foundations for Osteopathic Medicine
Author : Robert C. Ward
Publisher : Lippincott Williams & Wilkins
Release Date : 2003
Category : Medical
Total pages :1285
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Thoroughly revised for its Second Edition, Foundations for Osteopathic Medicine is the only comprehensive, current osteopathic text. It provides broad, multidisciplinary coverage of osteopathic considerations in the basic sciences, behavioral sciences, family practice and primary care, and the clinical specialties and demonstrates a wide variety of osteopathic manipulative methods. This edition includes new chapters on biomechanics, microbiology and infectious diseases, health promotion and maintenance, osteopathic psychiatry, emergency medicine, neuromusculoskeletal medicine, rehabilitation, sports medicine, progressive inhibition of neuromuscular structures, visceral manipulation, A.T. Still osteopathic methods, treatment of acutely ill hospital patients, somatic dysfunction, clinical research and trials, outcomes research, and biobehavioral interactions with disease and health. Compatibility: BlackBerry(R) OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile(TM) Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC

Pain and Disability

Pain and Disability
Author : Institute of Medicine,Committee on Pain, Disability, and Chronic Illness Behavior
Publisher : National Academies Press
Release Date : 1987-01-01
Category : Medical
Total pages :320
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Pain--it is the most common complaint presented to physicians. Yet pain is subjective--it cannot be measured directly and is difficult to validate. Evaluating claims based on pain poses major problems for the Social Security Administration (SSA) and other disability insurers. This volume covers the epidemiology and physiology of pain; psychosocial contributions to pain and illness behavior; promising ways of assessing and measuring chronic pain and dysfunction; clinical aspects of prevention, diagnosis, treatment, and rehabilitation; and how the SSA's benefit structure and administrative procedures may affect pain complaints.

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics

Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics
Author : Carl Faingold,Hal Blumenfeld
Publisher : Academic Press
Release Date : 2013-12-26
Category : Medical
Total pages :512
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Neuronal Networks in Brain Function, CNS Disorders, and Therapeutics, edited by two leaders in the field, offers a current and complete review of what we know about neural networks. How the brain accomplishes many of its more complex tasks can only be understood via study of neuronal network control and network interactions. Large networks can undergo major functional changes, resulting in substantially different brain function and affecting everything from learning to the potential for epilepsy. With chapters authored by experts in each topic, this book advances the understanding of: How the brain carries out important tasks via networks How these networks interact in normal brain function Major mechanisms that control network function The interaction of the normal networks to produce more complex behaviors How brain disorders can result from abnormal interactions How therapy of disorders can be advanced through this network approach This book will benefit neuroscience researchers and graduate students with an interest in networks, as well as clinicians in neuroscience, pharmacology, and psychiatry dealing with neurobiological disorders. Utilizes perspectives and tools from various neuroscience subdisciplines (cellular, systems, physiologic), making the volume broadly relevant Chapters explore normal network function and control mechanisms, with an eye to improving therapies for brain disorders Reflects predominant disciplinary shift from an anatomical to a functional perspective of the brain Edited work with chapters authored by leaders in the field around the globe – the broadest, most expert coverage available

An Introduction to Pain and Its Relation to Nervous System Disorders

An Introduction to Pain and Its Relation to Nervous System Disorders
Author : Anna A. Battaglia
Publisher : John Wiley & Sons
Release Date : 2016-05-02
Category : Science
Total pages :440
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"Provides an accessible overview of the latest developments in the science underpinning pain research"--

The Neurological Basis of Pain

The Neurological Basis of Pain
Author : Marco Pappagallo
Publisher : McGraw Hill Professional
Release Date : 2005
Category : Medical
Total pages :673
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Pappagallo (neurology, Albert Einstein College of Medicine; chronic pain, Beth Israel Medical Center) compiles the latest work from international contributors on the scientific basis of pain medicine, issues related to the pain physician, pain syndromes and disorders, and therapies. Some topics examined include opioid pharmacology, brain imaging of

Pain Imaging

Pain Imaging
Author : Kenneth Lyman Casey,M. Catherine Bushnell
Publisher : International Assn for the Study of Pain
Release Date : 2000
Category : Medical
Total pages :248
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Imaging of the Human Brain in Health and Disease

Imaging of the Human Brain in Health and Disease
Author : Philip Seeman,Bertha Madras
Publisher : Elsevier
Release Date : 2013-11-15
Category : Medical
Total pages :532
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Brain imaging technology remains at the forefront of advances in both our understanding of the brain and our ability to diagnose and treat brain disease and disorders. Imaging of the Human Brain in Health and Disease examines the localization of neurotransmitter receptors in the nervous system of normal, healthy humans and compares that with humans who are suffering from various neurologic diseases. Opening chapters introduce the basic science of imaging neurotransmitters, including sigma, acetylcholine, opioid, and dopamine receptors. Imaging the healthy and diseased brain includes brain imaging of anger, pain, autism, the release of dopamine, the impact of cannabinoids, and Alzheimer's disease. This book is a valuable companion to a wide range of scholars, students, and researchers in neuroscience, clinical neurology, and psychiatry, and provides a detailed introduction to the application of advanced imaging to the treatment of brain disorders and disease. A focused introduction to imaging healthy and diseased brains Focuses on the primary neurotransmitter release Includes sigma, acetylcholine, opioid, and dopamine receptors Presents the imaging of healthy and diseased brains via anger, pain, autism, and Alzheimer's disease

Chronic Pain

Chronic Pain
Author : Gary W. Jay
Publisher : CRC Press
Release Date : 2007-06-20
Category : Health & Fitness
Total pages :314
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Providing a general approach to the understanding and management of all forms of chronic pain, this book offers a clear and reader-friendly format that clarifies procedures in the diagnosis, assessment, and treatment of the most common chronic non-cancer pain entities. Describing various types of intractable non-cancer pain, including neuropathic, somatic, and visceral pain, this source discusses the many available types of treatments, including opioid and adjunctive pain medications, and the safe and proper use of narcotics for treating chronic pain.

Essentials of Pain Medicine E-book

Essentials of Pain Medicine E-book
Author : Honorio Benzon,Srinivasa N. Raja,Scott E. Fishman,Spencer S Liu,Steven P Cohen
Publisher : Elsevier Health Sciences
Release Date : 2011-06-30
Category : Medical
Total pages :592
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This third edition of Essentials of Pain Medicine offers an accessible and concise, yet complete, overview of today's theory and practice of pain medicine and regional anesthesia. From a review of basic considerations through local anesthetics and nerve block techniques, this book provides the reader with an excellent tool for exam review or practice of Pain Management. Organized in a concise, practical quick-reference format. All chapters are brief and easy to read quickly. Offers specific strategies for the evaluation and management of a full range of pain syndromes, including cancer pain. Features over 230 diagrams, illustrations, summary charts and tables that clarify the information and make it easy to apply. Discusses the latest drugs and therapeutic approaches, such as acupuncture. Presents the management of pain for every setting where it is practiced, including the emergency room, the critical care unit, and the pain clinic. Includes new topics such as: imaging in pain medicine, radiation safety, issues associated with the use of narcotics, intraarticular and intraperitoneal use of opioids, pain management in the emergency room and in the intensive care unit, pain management issues during pregnancy, geriatric pain, and hospice care and end-of-life issues. New chapters on interventional procedures include discography, intradiscal electrothermal coagulation (IDET), vertebroplasty, and piriformis injections. Truncal blocks and neuraxial blocks and anticoagulants are added to the section on nerve blocks.