November 30, 2020

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CNS Regeneration

CNS Regeneration
Author : Jeffrey Kordower,Mark H. Tuszynski
Publisher : Elsevier
Release Date : 2011-04-28
Category : Science
Total pages :526
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This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury. Incorporates information gained from cutting-edge photomicroscopy techniques Includes current information on clinical trials Presents chapters on stem cells and other novel treatments for diseases of the CNS

CNS Regeneration

CNS Regeneration
Author : Mark H. Tuszynski,Jeffrey Kordower
Publisher : Elsevier
Release Date : 1998-10-27
Category : Science
Total pages :678
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CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. The first comprehensive, authoritative volume on the topic of CNS regeneration Reviews current therapeutic approaches Editors and authors are experts in the field Appeals to those interested in basic science as well as those concerned with its medical application

CNS Regeneration

CNS Regeneration
Author : Mark H. Tuszynski,Jeffrey Kordower
Publisher : Academic Press
Release Date : 1999
Category : Medical
Total pages :678
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CNS Regeneration focuses on some of the leading current neurological disease models and methods for promoting central nervous system regeneration. Editors and authors are experts in the field, with experience in basic as well as applied neuroscience. In a comprehensive, logical manner, the book unites important basic science advances in neuroscience with novel medical strategies. The first comprehensive, authoritative volume on the topic of CNS regeneration Reviews current therapeutic approaches Editors and authors are experts in the field Appeals to those interested in basic science as well as those concerned with its medical application

Opportunities and Challenges of the Therapies Targeting CNS Regeneration

Opportunities and Challenges of the Therapies Targeting CNS Regeneration
Author : H.D. Perez,B. Mitrovic,A. Baron Van Evercooren
Publisher : Springer Science & Business Media
Release Date : 2007-01-19
Category : Medical
Total pages :186
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The therapeutic options for the treatment of Multiple Sclerosis (MS) and other neurodegenerative and traumatic diseases such as spinal cord injury, Alzheimer's, Parkinson's disease, etc. have experienced enormous progress over recent years. Despite these encouraging developments, available therapies are only partially effective, and the ultimate goal is still far from being attained. Improved understanding of the cellular and molecular mechanisms of the pathogenesis of neurodegeneration and demyelination has led to a variety of new therapeutic targets and approaches. In addition to modulation of the inflammatory process (MS) and classical neuroprotection (stroke, AD), therapeutic approaches focusing on active remyelinization and neuronal regeneration have become increasingly important. Based on current concepts, this book summarizes new therapeutic approaches.

CNS Regeneration

CNS Regeneration
Author : Jeffrey Kordower,Mark H. Tuszynski
Publisher : Elsevier
Release Date : 2011-04-28
Category : Science
Total pages :526
GET BOOK

This second edition of CNS Regeneration updates the burgeoning field of regeneration in the Central Nervous System (CNS) from molecular, systems, and disease-based perspective. While the book covers numerous areas in detail, special emphasis is given to discussions of movement disorders such as Parkinson’s disease, Alzheimer’s disease, and spinal cord injury. Incorporates information gained from cutting-edge photomicroscopy techniques Includes current information on clinical trials Presents chapters on stem cells and other novel treatments for diseases of the CNS

Axonal Regeneration in the Mammalian Central Nervous System

Axonal Regeneration in the Mammalian Central Nervous System
Author : Dorothy E. Oorschot,David G. Jones
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :121
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This state-of-the-art review links the experimental data into a cohesive and critical account of CNS regeneration. Research findings are discussed in terms of their relevance to one (or more) of thirteen hypotheses concerned with regeneration in the mammalian CNS. Research findings reviewed include: regeneration in developing mammals and in submammalian vertebrates, the use of transplants and/or pharmacological treatments, in vitro studies on neurotrophic and neurite promoting factors and their potential relevance to CNS regeneration in vivo, and in vitro studies on the types of glial cells that may be responsible for enhancing or suppressing axonal re-growth.

Neural Transplantation, CNS Neuronal Injury, and Regeneration

Neural Transplantation, CNS Neuronal Injury, and Regeneration
Author : Joe Marwah,Herman Teitelbaum,Kedar N. Prasad
Publisher : CRC Press
Release Date : 1994-02-23
Category : Medical
Total pages :304
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This unique reference presents studies from leading laboratories that are studying the effects of CNS transplants on neuronal plasticity and recovery of function after CNS injury. Topics covered include tropic influences, reinnervation patterns, and prevention of cell death that range from pre-clinical models of Parkinson's disease in primates to studies of restoration of circadian rhythms in rats. Techniques of neurotransplantation are presented, including current limitations and future projections of advancement.

Handbook of Innovations in Central Nervous System Regenerative Medicine

Handbook of Innovations in Central Nervous System Regenerative Medicine
Author : António Salgado
Publisher : Elsevier
Release Date : 2020-06-10
Category : Medical
Total pages :710
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Handbook of Innovations in CNS Regenerative Medicine provides a comprehensive overview of the CNS regenerative medicine field. The book describes the basic biology and anatomy of the CNS and how injury and disease affect its balance and the limitations of the present therapies used in the clinics. It also introduces recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies. Finally, the book presents successful cases of translation of basic research to first-in-human trials and the steps needed to follow this path. Areas such as cell transplantation approaches, bio and neuro-engineering, molecular/pharmacotherapy therapies and enabling technologies are key in regenerative medicine are covered in the book, along with regulatory and ethical issues. Describes the basic biology and anatomy of the CNS and how injury and disease affect its balance Discusses the limitations of present therapies used in the clinics Introduces the recent trends in different fields of CNS regenerative medicine, including cell transplantation, bio and neuro-engineering, molecular/pharmacotherapy therapies, and enabling technologies Presents successful cases of translation of basic research to first-in-human trials, along with the steps needed to follow this path

Degeneration and Regeneration in the Nervous System

Degeneration and Regeneration in the Nervous System
Author : Norman Saunders,Katarzyna Dziegielewska
Publisher : CRC Press
Release Date : 2003-09-02
Category : Medical
Total pages :348
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Degeneration and Regeneration in the Nervous System brings together an international team of contributors to produce a series of critical reviews appraising key papers in the field. The pace of research on brain and spinal cord injury quickened considerably in the last ten years and there is much that is new and important that is covered in this book. However, there is still a long way to go before our knowledge will explain fully why the central nervous system has such a limited capacity for regeneration, and before experimental solutions can be applied to the patient. With emphasis on actual and therapeutic importance of the work reviewed, Degeneration and Regeneration in the Nervous System is a useful overview for graduate students, their teachers and researchers working in this field.

Axonal Regeneration in the Central Nervous System

Axonal Regeneration in the Central Nervous System
Author : Nicholas A Ingoglia,Marion Murray
Publisher : Informa Health Care
Release Date : 2000-09-29
Category : Medical
Total pages :736
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Summarizing a review of research into factors that regulate, stimulate, and prevent regeneration in the central nervous system (CNS), this comprehensive reference progresses further into answering and resolving neuron capacity for axon regeneration in the mammalian CNS. Axonal Regeneration in the Central Nervous System analyzes axonal regeneration, reinnervation, and functional recovery in lower vertebrates examines the correlation between developmental age and the ability to regenerate considers mammalian neuron responses at the cell body, site of injury, and in the distal nerve, including apoptic cell death, and inflammatory and glial responses to injury reviews genomic responses to axotomy with a comparative description of transcribed genes from successfully regenerating neurons and neurons incapable of regrowth discusses how growing axons may induce the expression of genes in glia/Schwann cells following axotomy and regeneration describes the use of gene therapy to deliver trophic and survival factors to injured neurons explores the hospitable environments of the peripheral nerve, olfactory ensheathing cells, and fetal cell transplants for regeneration discusses results from applications of fetal CNS tissue to human spinal cord injuries and much more!

Stem Cell and Gene-Based Therapy

Stem Cell and Gene-Based Therapy
Author : Alexander Battler,Jonathan Leor
Publisher : Springer Science & Business Media
Release Date : 2007-06-26
Category : Medical
Total pages :422
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Regenerative medicine – stem cell and gene-based therapy – offers a new approach for restoring function of damaged organs and tissues. This is the first book to cover the major new aspects and field of regenerative medicine. This title is therefore a timely addition to the literature. It brings together the major approaches to regenerative medicine in one text, which ensures that techniques learnt in one discipline are disseminated across other areas of medicine.

Model Organisms in Spinal Cord Regeneration

Model Organisms in Spinal Cord Regeneration
Author : Catherina G. Becker,Thomas Becker
Publisher : John Wiley & Sons
Release Date : 2007-03-30
Category : Medical
Total pages :423
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This handbook provides a comprehensive overview for students, clinicians and researchers planning to enter the field of neural regeneration, combining the latest knowledge with an understanding of all important model organisms in one handy volume. By covering the strengths and weaknesses as well as possible applications of different models it saves researchers both time and resources in their choice of the appropriate model organism. An equally valuable introduction for the novice planning to enter the field.

Sensory Nerve Regeneration at the CNS-PNS Interface

Sensory Nerve Regeneration at the CNS-PNS Interface
Author : Xiaoqing Tang
Publisher : Unknown
Release Date : 2012
Category : Medicine
Total pages :129
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Sensory Nerve Regeneration at the CNS-PNS Interface.

Immunosuppressant Analogs in Neuroprotection

Immunosuppressant Analogs in Neuroprotection
Author : Cesario V. Borlongan,Ole Isacson,Paul R. Sanberg
Publisher : Springer Science & Business Media
Release Date : 2002-11-20
Category : Medical
Total pages :378
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An authoritative survey of the most recent scientific evidence showing how cyclosporin, FK-506, and their analogs-the neuroimmunophilins-evolved from being purely immunosuppressant "drugs" to neuroprotective "agents". The book focuses on recent preclinical evidence that demonstrates the neurotrophic/neuroprotective effects of immunosuppressants when administered alone or when combined with neural transplantation therapy in animal models of neurological disorders.

The Physiological Basis of Rehabilitation Medicine

The Physiological Basis of Rehabilitation Medicine
Author : John A. Downey,Stanley J. Myers,Erwin G. Gonzalez
Publisher : Butterworth-Heinemann
Release Date : 2013-10-22
Category : Medical
Total pages :782
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The Physiological Basis of Rehabilitation Medicine: Second Edition presents a comprehensive examination of the management of patients with functional impairments due to disease or trauma. It discusses the distinction between disabilities and impairments per se. It addresses the method in which the human body adapts and compensates for the stress produced by physical injuries. Some of the topics covered in the book are the physiology of cerebellum and basal ganglia; description of upper and lower motor neurons; anatomy of the vascular supply to the brain; characteristics of the autonomic nervous system; structure, chemistry, and function of skeletal muscle; the receptors in muscle; and cardiopulmonary physiology. The role of muscle spindles in perception of limb position and movement is fully covered. An in-depth account of the physiology of synovial joints and articular cartilage are provided. The cellular and glandular components of the skin are completely presented. A chapter is devoted to the factors involve in wound healing. Another section focuses on the nerve conduction and neuromuscular transmission. The book can provide useful information to doctors, dermatologists, students, and researchers.