April 13, 2021

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Cytokines and the Brain

Cytokines and the Brain
Author : Anonim
Publisher : Elsevier
Release Date : 2008-06-18
Category : Science
Total pages :608
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This book opens a new page of neuro-immunobiology providing substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease. The volume is a collection of complex, new data drawn from multiple areas of investigation in the field. The contents summarize current understanding on the presence and function of CNS cytokines and their receptors in a variety of CNS cells during health and disease. The chapters are a collection of complex, new data demonstrating the presence and synthesis of cytokines in brain cells, as well as their receptors on cell membranes in health and disease. The strength of the volume are the descriptions of the authors own investigations, together with those of others in the field pertaining to a large number of cytokines in brain function, as well as mechanisms involved in the development of CNS disorders, including multiple sclerosis and Alzheimer’s disease. Also included are novel approaches to the treatment of CNS disorders based on new experimental data. The contributors to this volume are internationally known scientists and clinical researchers in their respective fields of investigation and treatment. *Opens a new page of neuro-immunobiology and provides substantive evidence for the promise of this field in the treatment of disease *Summarizes current understanding on the presence and function of central nervous system (CNS) cytokines and their receptors in a variety of CNS cells during health and disease *Includes novel approaches to the treatment of CNS disorders based on new experimental data *Offers new insight into triggers for the development of autoimmune diseases in the brain and the possibilities for treatment

Cytokines and Mental Health

Cytokines and Mental Health
Author : Ziad Kronfol
Publisher : Springer Science & Business Media
Release Date : 2003-01-31
Category : Medical
Total pages :426
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Cytokines and Mental Health explores the relationship between cytokines, neural circuitry and mental health. It is interdisciplinary and "translational", bringing together information that spans the spectrum from the molecular and cellular levels to the patient and the clinic. Content includes chapters that discuss cytokine pathways in the brain, the neurochemical and neuroendocrine effects of cytokines, and the behavioral effects of cytokines including sickness behavior. These chapters in basic research are followed by a more clinical section that discusses the role of cytokines in neuropsychiatric disorders such as major depression, schizophrenia and Alzheimer's disease. The book offers different things to different people. It should be of great interest to neuroscientists and immunologists working in the field of psychoneuroimmunology. It would also greatly benefit mental health professionals including psychiatrists, psychologists and clinicians of diverse background who are interested in mind-body medicine.

Cytokines and Pain

Cytokines and Pain
Author : L.R. Watkins,S.F. Maier
Publisher : Springer
Release Date : 2013-03-08
Category : Medical
Total pages :232
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Within the past few years, it has become recognized that the immune system communicates to the brain. Substances released from activated immune cells (cytokines) stimulate peripheral nerves, thereby signaling the brain and spinal cord that infection/inflammation has occurred. Additionally, peripheral infection/inflammation leads to de novo synthesis and release of cytokines within the brain and spinal cord. Thus, cytokines effect neural activation both peripherally and centrally. Through this communication pathway, cytokines such as interleukin-1, interleukin-6 and tumor necrosis factor markedly alter brain function, physiology and behavior. One important but underrecognized aspect of this communication is the dramatic impact that immune activation has on pain modulation. The purpose of this book is to examine, for the first time, immune-to-brain communication from the viewpoint of its effect on pain processing. It is aimed both at the basic scientist and health care providers, in order to clarify the major role that substances released by immune cells play in pain modulation. This book contains chapters contributed by all of the major laboratories focused on understanding how cytokines modulate pain. These chapters provide a unique vantage point from which to examine this question, as the summarized work ranges from evolutionary approaches across diverse species, to the basics of the immune response, to the effect of cytokines on peripheral and central nervous system sites, to therapeutic potential in humans.

Brain Neurosecretory Cytokines

Brain Neurosecretory Cytokines
Author : Armen A. Galoyan
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :188
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Brain Neurosecretory Cytokines: Immune Response and Neuronal Survival summarizes the biological and chemical data of signal molecules of the brain neuroendocrine immune system, mainly proline-rich peptides, which play an important role in the regulation of immune response, neuronal survival, hematopoiesis, and adaptation. The author also describes the role of PRPs for the protection of neurons against neurodegenerative disturbances and diseases. Brain Neurosecretory Cytokines: Immune Response and Neuronal Survival will be of great aid to the researchers and students in various areas of neurobiological profile (neurochemistry, neuroendocrinology, neurophysiology, and endocrinology).

Immunoregulatory Cytokines and Cell Growth

Immunoregulatory Cytokines and Cell Growth
Author : Julius M. Cruse,R. E. Lewis
Publisher : S Karger Ag
Release Date : 1989
Category : Medical
Total pages :224
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Neurobiology of Cytokines

Neurobiology of Cytokines
Author : Errol B. De Souza
Publisher : Academic Press
Release Date : 2013-10-22
Category : Health & Fitness
Total pages :368
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Neurobiology of Cytokines, Part A provides an overview of the effects of cytokines in the brain and in the endocrine system. The book discusses the general aspects of cytokines, including the endogenous agonists and antagonists, their receptors, their second messengers, and transport mechanisms for cytokines across the blood-brain barrier. The text also describes the anatomical localization of cytokines, cytokine receptors, and their respective mRNA in brain and in endocrine tissues. The methods for evaluating the in vivo as well as in vitro actions of cytokines on hormone secretion are also considered. The book further tackles the synthesis and release of cytokines and their central nervous system actions; and the methodology for studying the role of cytokines in human neuropathological conditions.

Handbook of Traumatic Brain Injury and Neurodegeneration

Handbook of Traumatic Brain Injury and Neurodegeneration
Author : R.J. Castellani
Publisher : IOS Press
Release Date : 2020-04-24
Category : Medical
Total pages :504
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Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.

European Cytokine Network

European Cytokine Network
Author : Anonim
Publisher : Unknown
Release Date : 1997
Category : Cytokines
Total pages :129
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Gulf War Illness and the Health of Gulf War Veterans

Gulf War Illness and the Health of Gulf War Veterans
Author : United States. Department of Veterans Affairs. Research Advisory Committee on Gulf War Veterans' Illnesses
Publisher : Unknown
Release Date : 2008
Category : Government publications
Total pages :454
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Questions surrounding Gulf War illness and other health problems resulting from service in the 1990-1991 Gulf War have long plagued veterans and government officials. This 450-page report brings together for the first time the full range of scientific research and government investigations on Gulf War illness. The comprehensive analysis resolves many questions about what caused Gulf War illness and what should be done to address this serious condition, which affects at least one in four Gulf War veterans.--Publisher description.

Cumulated Index Medicus

Cumulated Index Medicus
Author : Anonim
Publisher : Unknown
Release Date : 1999
Category : Medicine
Total pages :129
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Dairy Calves and Heifers

Dairy Calves and Heifers
Author : Anonim
Publisher : Natural Resource Agriculture and Engineering Service (Nraes)
Release Date : 2005
Category : Calves
Total pages :398
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Index Medicus

Index Medicus
Author : Anonim
Publisher : Unknown
Release Date : 2003
Category : Medicine
Total pages :129
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Cytokines and the CNS

Cytokines and the CNS
Author : Richard M. Ransohoff,Etty N. Benveniste
Publisher : CRC Press
Release Date : 2005-10-31
Category : Medical
Total pages :384
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Provides Insight into How Cytokine Action Impacts the Physiology and Pathology of the CNS. As with the first edition of Cytokines and the CNS, this completely updated and revised edition introduces neurobiologists to cytokine biology and immunologists to the unique functions of cytokines in CNS physiology. The dramatically accelerating interest in cytokines and cytokine/chemokine signaling over the past several years has encouraged an explosion of literature on cytokines. The similarity between factors involved in inflammation or immunity, and those implicated in neural development, physiology, and repair has become so apparent that familiarity with cytokines must now be considered an essential element in the neurobiologist’s cognitive tool-kit. Conversely, for immunobiologists, the concepts elaborated by neurobiologists to understand developmental patterning and networked organ function continue to evolve in such a way that comprehension of cytokine action in the CNS can only enhance a further understanding of immune system function. Cytokines and the CNS, Second Edition is patterned after the first edition; however, the wealth of knowledge now available adds a tremendous amount of insight and new implications. To guarantee a fresh perspective, the editors made a conscious choice to utilize an entirely new set of contributors, all experts in various aspects of cytokine research. Cytokines and the CNS, Second Edition starts with a chapter on the CNS, focusing on pathological reactions to insult. Next, come three chapters on cytokine biology, followed by four chapters that integrate cytokine biology into basic CNS processes (development; inflammation; immunity; degeneration/repair), after which five chapters apply this body of knowledge to disease or pathology. The book closes with a look at the application of cytokine biology to the treatment of disease, a brand new area of research.

Periodicum Biologorum

Periodicum Biologorum
Author : Anonim
Publisher : Unknown
Release Date : 2006
Category : Biology
Total pages :129
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Coping with the Environment

Coping with the Environment
Author : Bruce S. McEwen,H. Maurice Goodman
Publisher : Unknown
Release Date : 2001
Category : Endocrine glands
Total pages :562
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This unique volume provides fresh insights into the neuroendocrine systems. Since the pioneering work of Claude Bernard and Walter Cannon there have been profound advances in biomedicin. With this has come an appreciation of the long time frame in which the environment produces both adaptive and maladaptive changes in an individual organism during the lifespan. Indeed, experiences early in life can have a life-long impact, and advances in behavioral and social sciences have interfaced with biology. This book begins by discussing the two main stress mediators, the catecholamines and the hypothalamic-pituitary-adrenal axis. It then deals with the neurobiology of fear, stress and coping and with biological aspects of stress and coping during the life course. Next it considers diurnal rhythms, sleep and immune defense mechanisms. Finally it discusses stress and coping in the social environment in both animal models and humans.