June 17, 2021

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Endothelium and Cardiovascular Diseases

Endothelium and Cardiovascular Diseases
Author : Protasio Lemos Da Luz,Peter Libby,Francisco Rafael Martins Laurindo,Antonio Carlos Palandri Chagas
Publisher : Academic Press
Release Date : 2018-02-03
Category : Medical
Total pages :758
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Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

The Endothelium in Cardiovascular Disease

The Endothelium in Cardiovascular Disease
Author : Thomas Luescher
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :197
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Since the endothelium plays such an important role in the pathophysiology of the circulatory system, the readers attention is directed here towards the possible involvement of these polypeptides in the aetiology of ischaemic heart disease, cerebrovascular accidents, hypertension, atherosclerosis and renal failure.

Endothelium and Cardiovascular Diseases

Endothelium and Cardiovascular Diseases
Author : Anonim
Publisher : Unknown
Release Date : 1999
Category :
Total pages :129
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Inflammation in Cardiovascular Diseases: Role of the Endothelium & Emerging Therapeutics

Inflammation in Cardiovascular Diseases: Role of the Endothelium & Emerging Therapeutics
Author : Chen Huei Leo,Cheng Xue Helena Qin,Owen Llewellyn Woodman
Publisher : Frontiers Media SA
Release Date : 2021-01-05
Category : Science
Total pages :129
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Cardiovascular Pharmacology: Endothelial Control

Cardiovascular Pharmacology: Endothelial Control
Author : Anonim
Publisher : Academic Press
Release Date : 2010-12-16
Category : Science
Total pages :336
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Cardiovascular disease remains a major cause of death and disability in developed countries and, increasingly so, in the developing world. Presented in this volume of Advances in Pharmacology are some of the most promising possibilities for treating large numbers of individuals afflicted with these conditions. Contains up-to-date reviews of the most important emerging cardiovascular therapies written by world leaders in the field

Diabetes and Cardiovascular Disease

Diabetes and Cardiovascular Disease
Author : Michael T. Johnstone,Aristidis Veves
Publisher : Springer Science & Business Media
Release Date : 2007-10-28
Category : Medical
Total pages :672
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The cause of diabetes mellitus is metabolic in origin. However, its major clinical manifestations, which result in most of the morbidity and mortality, are a result of its vascular pathology. In fact, the American Heart Association has recently stated that, “from the point of view of cardiovascular medicine, it may be appropriate to say, diabetes is a cardiovascular disease” (1). But diabetic vascular disease is not limited to just the macrovasculature. Diabetes mellitus also affects the microcirculation with devastating results, including nephropathy, neuropathy, and retinopathy. Diabetic nephropathy is the leading cause of end-stage renal disease in the United States, while diabetic retinopathy is the leading cause of new-onset blindness in working-age Americans. The importance of this text on Diabetes and Cardiovascular Disease is evident by the magnitude of the population affected by diabetes mellitus. Over 10 million Americans have been diagnosed with diabetes mellitus, while another 5 million remain undiagnosed. The impact from a public health perspective is huge and increasing. As the population of the United States grows older, more sedentary, and obese, the risk of developing diabetes and its complications will increase. Epidemiological studies have identified diabetes mellitus as a major independent risk factor for cardiovascular disease. Over 65% of patients with diabetes mellitus die from a cardiovascular cause. The prognosis of patients with diabetes mellitus who develop overt clinical cardiovascular disease is much worse than those cardiovascular patients free of diabetes mellitus.

Endothelial Dysfunction

Endothelial Dysfunction
Author : Trent H. Keaton
Publisher : Nova Science Pub Incorporated
Release Date : 2014-01-01
Category : Medical
Total pages :261
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The endothelium is a thin mono-cellular layer which covers the inner surface of the blood vessels, separating the circulating blood from the tissues and also has the responsibility for uninterrupted maintenance of circulation to all the vital tissues. Endothelium is a very active organ, it works as a receptor-effector organ and responds to each physical or chemical stimulus with the release of the appropriate substance with which it may maintain vasomotor balance and vascular-tissue homeostasis. It has the property of producing, independently, both agonistic and antagonistic substances that help to keep homeostasis and its function is not only autocrine, but also paracrine and endocrine. In this way it modulates the vascular smooth muscle cells producing relaxation or contraction, and therefore vasodilatation or vasoconstriction. The vascular endothelium is vulnerable to maximum wear and tear due to its positioning and requires prompt regeneration of the cells. Whenever the imbalance between substances with vasodilating, antimitogenic, and antithrombogenic properties and substances with vasoconstricting, prothrombotic and proliferative characteristics takes place, it causes a pathological condition known as endothelial dysfunction. These substances intervenes in cell proliferation and migration, in leukocyte adhesion and activation and in immunological and inflammatory processes, further which is responsible for apoptosis of vascular endothelial cells resulting in overall endothelial dysfunction and vasculopathy. This book discusses, in further detail, the risk factors, and the role of endothelial dysfunction in cardiovascular diseases and therapeutic approaches to dealing with endothelial dysfunction.

Endothelial Vasoactive Substances and Cardiovascular Disease

Endothelial Vasoactive Substances and Cardiovascular Disease
Author : Thomas Felix Lüscher
Publisher : S Karger Ag
Release Date : 1988
Category : Medical
Total pages :133
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Vascular Endothelium in Human Physiology and Pathophysiology

Vascular Endothelium in Human Physiology and Pathophysiology
Author : Patrick J Vallance,David J. Webb
Publisher : CRC Press
Release Date : 2003-09-02
Category : Medical
Total pages :302
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Endothelial dysfunction is now regarded as an early marker of vascular disease and therefore an important target for therapeutic intervention and discovery of novel treatments. Ideal for both basic and clinical scientists, whether in industry or academia, and physicians, Vascular Endothelium in Human Physiology and Pathophysiology provides an up-to-date review of the vascular functions of the endothelium and its role in key areas of cardiovascular disease. It focuses on evidence from studies in humans.

Cardiovascular Disease and Endothelium

Cardiovascular Disease and Endothelium
Author : Anonim
Publisher : Unknown
Release Date : 1995
Category : Vascular endothelium
Total pages :94
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Endothelium

Endothelium
Author : Ayse Basak Engin,Atilla Engin
Publisher : CRC Press
Release Date : 2013-05-29
Category : Medical
Total pages :468
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The function and life span of endothelial cells have a large impact upon the quality and expectancy of an individual's life. During low perfusion, the adaptation of different cells to hypoxia precipitate the aggressive progression of diseases. Although the clinical studies have convincingly shown that endothelial dysfunction occurs whenever the biological functions or bioavailability of nitric oxide are impaired, in all these scenarios, the role of endothelial cell-destructive process cross-talk is yet poorly understood. This book focuses on the contribution of molecular mechanisms to endothelial dysfunction in related metabolic disorders.

Endothelial Function and Cardiovascular Disease

Endothelial Function and Cardiovascular Disease
Author : Arduino Mangoni
Publisher : Unknown
Release Date : 2006
Category : Atherosclerosis
Total pages :6
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Angiogenesis and Cardiovascular Disease

Angiogenesis and Cardiovascular Disease
Author : J. Anthony Ware,Michael Simons
Publisher : Oxford University Press, USA
Release Date : 1999
Category : Health & Fitness
Total pages :360
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Angiogenesis and Cardiovascular Disease provides a comprehensive revie w of the basic scientific and clinical advances in the field of angiog enesis, and its role in the human cardiovascular system. The material presented draws from multiple disciplines, integrating information in a single source. Topics addressed focus first on aspects of developmen t and normal biology of the vasculature, and then on angiogenesis and how it is involved in the pathophysiology and therapy of ischemic card iovascular disease. Vascular development, endothelial cell biology, th e vascular matrix, and growth factors are discussed. Up to date inform ation on current clinical trials, and practical advice concerning appl ication to cardiovascular therapeutic options, are also stressed.

Endothelial Function in Cardiovascular Disease

Endothelial Function in Cardiovascular Disease
Author : Haralambos Gavras,Irene Gavras
Publisher : Unknown
Release Date : 1996
Category : Bradykinin
Total pages :58
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The Endothelium in Cardiovascular Disease

The Endothelium in Cardiovascular Disease
Author : Thomas F. Luscher
Publisher : Unknown
Release Date : 1995-08-01
Category : Medical
Total pages :129
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