January 25, 2021

Download Ebook Free Essentials Of Noncoding RNA In Neuroscience

Essentials of Noncoding RNA in Neuroscience

Essentials of Noncoding RNA in Neuroscience
Author : Davide De Pietri Tonelli
Publisher : Academic Press
Release Date : 2017-06-14
Category : Science
Total pages :338
GET BOOK

Essentials of Noncoding RNA in Neuroscience: Ontogenetics, Plasticity of the Vertebrate Brain focuses on the role of miRNAs in neurogenesis, gliogenesis, neuronal network formation, and the cell biology of forebrain development. The important role miRNAs play in neuronal maturation, neocortex function, and in some neurodevelopmental disorders is discussed, as are the computational challenges and methods used in the identification of miRNA targets. This book is a valuable reference for neuroscientists who wish to better understand the role of miRNAs in complex processes. It is of strong interest to those working to develop enabling technologies to detect and monitor miRNA expression and function, and to evaluate its roles in neural progenitor proliferation/differentiation, neuronal plasticity, and learning and memory. Discusses the unique features of neural miRNAs Details functional investigation of miRNA actions and current experimental approaches Includes extensive coverage of miRNA biology, developmental and postnatal neurogenesis, and computational challenges for miRNA target identification Contains thorough discussion of the transcriptional control of miRNA expression in forebrain development and in specific neuronal subtypes, as well as miRNA function in neurogenesis, neuronal network maturation, plasticity, gliogenesis, and dysfunction Provides an overview of miRNA roles in neurodevelopmental disorders and their possible role in the evolution of the neocortex

Essentials of Surgical Pediatric Pathology with DVD-ROM

Essentials of Surgical Pediatric Pathology with DVD-ROM
Author : Marta C. Cohen,Irene Scheimberg
Publisher : Cambridge University Press
Release Date : 2015-02-05
Category : Medical
Total pages :524
GET BOOK

Highly illustrated, practical yet comprehensive bench manual for general pathologists encountering pediatric cases, and pediatric pathology trainees.

Essentials of Abnormal Psychology

Essentials of Abnormal Psychology
Author : V. Mark Durand,David H. Barlow
Publisher : Nelson Education
Release Date : 2015
Category : Psychology
Total pages :736
GET BOOK

Revised to reflect DSM-5, this briefer version of Durand and Barlow’s widely taught text fully describes abnormal psychology through the authors’ standard-setting integrative approach--the most modern, scientifically valid method for studying the subject. Through this approach, students learn that psychological disorders are rarely caused by a single influence, but rooted in the interaction among multiple factors: biological, psychological, cultural, social, familial, and even political. A conversational writing style, consistent pedagogy, and real case profiles--95 percent from the authors’ own case files--provide a realistic context for the scientific findings of the book. In addition, these features ensure that readers never lose sight of the fact that real people are behind the DSM-5 criteria, the theories, and the research. Important Notice: Media content referenced within the product description or the product text may not be available in the ebook version.

MicroRNA in Regenerative Medicine

MicroRNA in Regenerative Medicine
Author : Chandan K. Sen
Publisher : Elsevier
Release Date : 2014-11-26
Category : Science
Total pages :1288
GET BOOK

This work encapsulates the uses of miRNA across stem cells, developmental biology, tissue injury and tissue regeneration. In particular contributors provide focused coverage of methodologies, intervention and tissue engineering. Regulating virtually all biological processes, the genome’s 1048 encoded microRNAs appear to hold considerable promise for the potential repair and regeneration of tissues and organs in future therapies. In this work, 50 experts address key topics of this fast-emerging field. Concisely summarizing and evaluating key findings emerging from fundamental research into translational application, they point to the current and future significance of clinical research in the miRNA area. Coverage encompasses all major aspects of fundamental stem cell and developmental biology, including the uses of miRNA across repair and regeneration, and special coverage of methodologies and interventions as they point towards organ and tissue engineering Multi-colour text layout with 150 colour figures to illustrate important findings Take home messages encapsulate key lessons throughout text Short chapters offer focused discussion and clear ‘voice’

Elements of Molecular Neurobiology

Elements of Molecular Neurobiology
Author : C. U. M. Smith
Publisher : John Wiley & Sons
Release Date : 2003-06-13
Category : Medical
Total pages :630
GET BOOK

This edition of the popular text incorporates recent advances in neurobiology enabled by modern molecular biology techniques. Understanding how the brain works from a molecular level allows research to better understand behaviours, cognition, and neuropathologies. Since the appearance six years ago of the second edition, much more has been learned about the molecular biology of development and its relations with early evolution. This "evodevo" (as it has come to be known) framework also has a great deal of bearing on our understanding of neuropathologies as dysfunction of early onset genes can cause neurodegeneration in later life. Advances in our understanding of the genomes and proteomes of a number of organisms also greatly influence our understanding of neurobiology. * Well known and widely used as a text throughout the UK, good reviews from students and lecturers. * Good complement to Fundementals of Psychopharmacology by Brian Leonard. This book will be of particular interest to biomedical undergraduates undertaking a neuroscience unit, neuroscience postgraduates, physiologists, pharmacologists. It is also a useful basic reference for university libraries. Maurice Elphick, Queen Mary, University of London "I do like this book and it is the recommended textbook for my course in Molecular Neuroscience. The major strength of the book is the overall simplicity of the format both in terms of layout and diagrams."

'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine
Author : Nosheen Masood,Saima Shakil Malik
Publisher : Springer Nature
Release Date : 2020-03-20
Category : Medical
Total pages :499
GET BOOK

This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.

Molecular Cell Biology

Molecular Cell Biology
Author : Harvey F. Lodish,Berk Lodish (Zipursky, Matsudaria, Baltimore, Darnell),Arnold Berk,James E. Darnell,S. Lawrence Zipursky,David Baltimore,Paul Matsudaira
Publisher : Scientific American Library
Release Date : 2000
Category : Cytology
Total pages :1084
GET BOOK

With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.

Bioinformatics

Bioinformatics
Author : Ibrokhim Y. Abdurakhmonov
Publisher : BoD – Books on Demand
Release Date : 2016-07-27
Category : Science
Total pages :268
GET BOOK

An interdisciplinary bioinformatics science aims to develop methodology and analysis tools to explore large-volume of biological data using conventional and modern computer science, statistics, and mathematics, as well as pattern recognition, reconstruction, machine learning, simulation and iterative approaches, molecular modeling, folding, networking, and artificial intelligence. Written by international team of life scientists, this Bioinformatics book provides some updates on bioinformatics methods, resources, approaches, and genome analysis tools useful for molecular sciences, medicine and drug designs, as well as plant sciences and agriculture. I trust chapters of this book should provide advanced knowledge for university students, life science researchers, and interested readers on some latest developments in the bioinformatics field.

Gene Expression and Regulation in Mammalian Cells

Gene Expression and Regulation in Mammalian Cells
Author : Fumiaki Uchiumi
Publisher : BoD – Books on Demand
Release Date : 2018-02-21
Category : Medical
Total pages :334
GET BOOK

"Central dogma" was presented by Dr. Francis Crick 60 years ago. The information of nucleotide sequences on DNAs is transcribed into RNAs by RNA polymerases. We learned the mechanisms of how transcription determines function of proteins and behaviour of cells and even how it brings appearances of organisms. This book is intended for scientists and medical researchers especially who are interested in the relationships between transcription and human diseases. This volume consists of an introductory chapter and 14 chapters, divided into 4 parts. Each chapter is written by experts in the basic scientific field. A collection of articles presented by active and laboratory-based investigators provides recent advances and progresses in the field of transcriptional regulation in mammalian cells.

Molecular Biology and Genetic Engineering

Molecular Biology and Genetic Engineering
Author : P. K. Gupta
Publisher : Rastogi Publications
Release Date : 2008
Category : Electronic books
Total pages :613
GET BOOK

PART I Molecular Biology 1. Molecular Biology and Genetic Engineering Definition, History and Scope 2. Chemistry of the Cell: 1. Micromolecules (Sugars, Fatty Acids, Amino Acids, Nucleotides and Lipids) Sugars (Carbohydrates) 3. Chemistry of the Cell . 2. Macromolecules (Nucleic Acids; Proteins and Polysaccharides) Covalent and Weak Non-covalent Bonds 4. Chemistry of the Gene: Synthesis, Modification and Repair of DNA DNA Replication: General Features 5. Organisation of Genetic Material 1. Packaging of DNA as Nucleosomes in Eukaryotes Techniques Leading to Nucleosome Discovery 6. Organization of Genetic Material 2. Repetitive and Unique DNA Sequences 7. Organization of Genetic Material: 3. Split Genes, Overlapping Genes, Pseudogenes and Cryptic Genes Split Genes or .Interrupted Genes 8. Multigene Families in Eukaryotes 9. Organization of Mitochondrial and Chloroplast Genomes 10. The Genetic Code 11. Protein Synthesis Apparatus Ribosome, Transfer RNA and Aminoacyl-tRNA Synthetases Ribosome 12. Expression of Gene . Protein Synthesis 1. Transcription in Prokaryotes and Eukaryotes 13. Expression of Gene: Protein Synthesis: 2. RNA Processing (RNA Splicing, RNA Editing and Ribozymes) Polyadenylation of mRNA in Prokaryotes Addition of Cap (m7G) and Tail (Poly A) for mRNA in Eukaryotes 14. Expression of Gene: Protein Synthesis: 3. Synthesis and Transport of Proteins (Prokaryotes and Eukaryotes) Formation of Aminoacyl tRNA 15. Regulation of Gene Expression: 1. Operon Circuits in Bacteria and Other Prokaryotes 16. Regulation of Gene Expression . 2. Circuits for Lytic Cycle and Lysogeny in Bacteriophages 17. Regulation of Gene Expression 3. A Variety of Mechanisms in Eukaryotes (Including Cell Receptors and Cell Signalling) PART II Genetic Engineering 18. Recombinant DNA and Gene Cloning 1. Cloning and Expression Vectors 19. Recombinant DNA and Gene Cloning 2. Chimeric DNA, Molecular Probes and Gene Libraries 20. Polymerase Chain Reaction (PCR) and Gene Amplification 21. Isolation, Sequencing and Synthesis of Genes 22. Proteins: Separation, Purification and Identification 23. Immunotechnology 1. B-Cells, Antibodies, Interferons and Vaccines 24. Immunotechnology 2. T-Cell Receptors and MHC Restriction 25. Immunotechnology 3. Hybridoma and Monoclonal Antibodies (mAbs) Hybridoma Technology and the Production of Monoclonal Antibodies 26. Transfection Methods and Transgenic Animals 27. Animal and Human Genomics: Molecular Maps and Genome Sequences Molecular Markers 28. Biotechnology in Medicine: l.Vaccines, Diagnostics and Forensics Animal and Human Health Care 29. Biotechnology in Medicine 2. Gene Therapy Human Diseases Targeted for Gene Therapy Vectors and Other Delivery Systems for Gene Therapy 30. Biotechnology in Medicine: 3. Pharmacogenetics / Pharmacogenomics and Personalized Medicine Phannacogenetics and Personalized 31. Plant Cell and Tissue Culture' Production and Uses of Haploids 32. Gene Transfer Methods in Plants 33. Transgenic Plants . Genetically Modified (GM) Crops and Floricultural Plants 34. Plant Genomics: 35. Genetically Engineered Microbes (GEMs) and Microbial Genomics References

Essentials of Cerebellum and Cerebellar Disorders

Essentials of Cerebellum and Cerebellar Disorders
Author : Donna L. Gruol,Noriyuki Koibuchi,Mario Manto,Marco Molinari,Jeremy D. Schmahmann,Ying Shen
Publisher : Springer
Release Date : 2016-11-22
Category : Medical
Total pages :656
GET BOOK

Essentials of the Cerebellum and Cerebellar Disorders is the first book of its kind written specifically for graduate students and clinicians. It is based on the 4-volume treatise, Handbook of the Cerebellum and Cerebellar Disorders (Springer, 2013), the definitive reference for scientists and neurologists in the field of cerebellar neurobiology. There have been fundamental advances in the basic science and clinical neurology of the cerebellum and its role in sensorimotor function and cognition. This monograph makes this large and expanding body of knowledge readily accessible to trainees and clinicians alike. The editors are world leaders in the field, and the chapters are authored by an international panel of experts drawn from ataxia clinics and cerebellar laboratories throughout North America, Europe and Asia. Essentials provides a solid grounding in the field of cerebellar research and ataxiology from cerebellar circuity to clinical practice, and it serves as a springboard to a deeper appreciation of both the principles and the complexities of cerebellar neurobiology. Clinicians are expected to have a deep appreciation of cerebellar disorders, not only in specialized ataxia clinics but also in adult and pediatric neurology, neurosurgery, psychiatry and neuropsychology practices, and in outpatient and inpatient rehabilitation settings. This book is an indispensable resource for students and practitioners navigating the evolving field of cerebellar motor and cognitive neurology. It also links to the more expansive Handbook for those who need to explore the topics in this monograph in greater depth.

Viruses: Essential Agents of Life

Viruses: Essential Agents of Life
Author : Günther Witzany
Publisher : Springer Science & Business Media
Release Date : 2012-11-13
Category : Science
Total pages :428
GET BOOK

A renaissance of virus research is taking centre stage in biology. Empirical data from the last decade indicate the important roles of viruses, both in the evolution of all life and as symbionts of host organisms. There is increasing evidence that all cellular life is colonized by exogenous and/or endogenous viruses in a non-lytic but persistent lifestyle. Viruses and viral parts form the most numerous genetic matter on this planet.

Mathematical Advances Towards Sustainable Environmental Systems

Mathematical Advances Towards Sustainable Environmental Systems
Author : James N. Furze,Kelly Swing,Anil K. Gupta,Richard H. McClatchey,Darren M. Reynolds
Publisher : Springer
Release Date : 2016-12-11
Category : Science
Total pages :347
GET BOOK

This edited volume focuses on how we can protect our environment and enhance environmental sustainability when faced with changes and pressures imposed by our expansive needs. The volume unites multiple subject areas within sustainability, enabling the techniques and philosophy in the chapters to be applied to research areas in environmental science, plant sciences, energy, biodiversity and conservation. The chapters from expert contributors cover topics such as mathematical modelling tools used to monitor diversity of plant species, and the stability of ecosystem services such as biogeochemical cycling. Empirical research presented here also brings together mathematical developments in the important fields of robotics including kinematics, dynamics, path planning, control, vision, and swarmanoids. Through this book readers will also discover about rainfall-runoff modelling which will give them a better idea of the effects of climate change on the sustainability of water resources at the watershed scale. Modelling approaches will also be examined that maximize readers insights into the global problem of energy transition, i.e. the switch to an energy production system using renewable resources only. Collective and discrete insights are made to assist with synergy which should progress well beyond this book. Insight is also given to assist policy formations, development and implementations. The book has a strong multi-disciplinary nature at its core, and will appeal to both generalist readers and specialists in information technology, mathematics, biology, physics, chemistry and environmental sciences.

Biomedical Sciences

Biomedical Sciences
Author : Raymond Iles,Suzanne Docherty
Publisher : John Wiley & Sons
Release Date : 2011-11-29
Category : Science
Total pages :440
GET BOOK

Biomedical Sciences is an indispensable, all encompassing core textbook for first/ second year biomedical science students that will support them throughout their undergraduate career. The book includes the key components of the IBMS accredited degree programmes, plus sections on actual practice in UK hospital laboratories (including the compilation of a reflective portfolio). The book is visually exciting, and written in an interesting and accessible manner while maintaining scientific rigour. Highlighted boxes within the text link the theory to actual clinical laboratory practice for example, the histopathology chapter includes a photographically illustrated flow chart of the progress of a specimen through the histopathology lab, so that students can actually see how the specimen reception/inking/cut-up/cassette/block/section/stain system works, with an emphasis on the safety procedures that ensure specimens are not confused).

Personalized Epigenetics

Personalized Epigenetics
Author : Trygve Tollefsbol
Publisher : Academic Press
Release Date : 2015-04-28
Category : Science
Total pages :610
GET BOOK

Personalized Epigenetics discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures that can guide both disorder and disease prevention and therapy. The book details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the diagnostic, prognostic, and therapeutic potential of the field, it also reviews the impact of the environment on epigenetic variations among individuals and the role of pharmacology and drug development in personalized epigenetics. Most importantly, the text covers personalized epigenetics from a disease-oriented perspective, presenting chapters that provide advances in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management. Discusses the core translatability of epigenetics to health management of individuals who have unique variations in their epigenetic signatures Details inter-individual variability in the major epigenetic process in humans consisting of DNA methylation, histone modifications, and noncoding RNA, and the consequent diagnostic, prognostic and therapeutic potential of the field Reviews the impact of the environment on epigenetic variations among individuals and the roles of pharmacology and drug development Devotes several chapters to the advances made in widespread disorders or diseases, including diabetes, cancer, autoimmune disorders, obesity, cardiovascular diseases, neurological disorders, and pain management