November 25, 2020

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Exposure Science in the 21st Century

Exposure Science in the 21st Century
Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Human and Environmental Exposure Science in the 21st Century
Publisher : National Academies Press
Release Date : 2012-10-28
Category : Nature
Total pages :210
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From the use of personal products to our consumption of food, water, and air, people are exposed to a wide array of agents each day--many with the potential to affect health. Exposure Science in the 21st Century: A Vision and A Strategy investigates the contact of humans or other organisms with those agents (that is, chemical, physical, and biologic stressors) and their fate in living systems. The concept of exposure science has been instrumental in helping us understand how stressors affect human and ecosystem health, and in efforts to prevent or reduce contact with harmful stressors. In this way exposure science has played an integral role in many areas of environmental health, and can help meet growing needs in environmental regulation, urban and ecosystem planning, and disaster management. Exposure Science in the 21st Century: A Vision and A Strategy explains that there are increasing demands for exposure science information, for example to meet needs for data on the thousands of chemicals introduced into the market each year, and to better understand the health effects of prolonged low-level exposure to stressors. Recent advances in tools and technologies--including sensor systems, analytic methods, molecular technologies, computational tools, and bioinformatics--have provided the potential for more accurate and comprehensive exposure science data than ever before. This report also provides a roadmap to take advantage of the technologic innovations and strategic collaborations to move exposure science into the future.

Exposure Science

Exposure Science
Author : Paul Lioy,Clifford Weisel
Publisher : Academic Press
Release Date : 2014-02-11
Category : Technology & Engineering
Total pages :116
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Exposure Science: Basic Principles and Applications provides a concise overview of the field of exposure science, from its origins in sanitation and occupational health, to its exciting involvement with emerging scientific concepts. Written by world-leading experts in the field of exposure science, this book provides all the basic understanding you need to employ the best tools and methods for measurement, analysis, and modeling of exposure. Exposure Science: Basic Principles and Applications is an invaluable introduction to exposure science for anyone working in the fields of environmental health, risk assessment, toxicology, or epidemiology. Focuses on and highlights the basic fundamentals, scientific goals, theories and tools of exposure science Examines the use of the exposome and eco-exposome concepts within the field of exposure science

Exposure Science

Exposure Science
Author : Paul Lioy,Clifford Weisel
Publisher : Academic Press
Release Date : 2014-02-11
Category : Technology & Engineering
Total pages :116
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Exposure Science: Basic Principles and Applications provides a concise overview of the field of exposure science, from its origins in sanitation and occupational health, to its exciting involvement with emerging scientific concepts. Written by world-leading experts in the field of exposure science, this book provides all the basic understanding you need to employ the best tools and methods for measurement, analysis, and modeling of exposure. Exposure Science: Basic Principles and Applications is an invaluable introduction to exposure science for anyone working in the fields of environmental health, risk assessment, toxicology, or epidemiology. Focuses on and highlights the basic fundamentals, scientific goals, theories and tools of exposure science Examines the use of the exposome and eco-exposome concepts within the field of exposure science

Exposure Science in the 21st Century

Exposure Science in the 21st Century
Author : Committee on Human and Environmental Exposure Science in the 21st Century,Board on Environmental Studies and Toxicology,Division on Earth and Life Studies,National Research Council
Publisher : National Academies Press
Release Date : 2012-10-12
Category : Science
Total pages :195
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From the use of personal products to our consumption of food, water, and air, people are exposed to a wide array of agents each day--many with the potential to affect health. Exposure Science in the 21st Century: A Vision and A Strategy investigates the contact of humans or other organisms with those agents (that is, chemical, physical, and biologic stressors) and their fate in living systems. The concept of exposure science has been instrumental in helping us understand how stressors affect human and ecosystem health, and in efforts to prevent or reduce contact with harmful stressors. In this way exposure science has played an integral role in many areas of environmental health, and can help meet growing needs in environmental regulation, urban and ecosystem planning, and disaster management. Exposure Science in the 21st Century: A Vision and A Strategy explains that there are increasing demands for exposure science information, for example to meet needs for data on the thousands of chemicals introduced into the market each year, and to better understand the health effects of prolonged low-level exposure to stressors. Recent advances in tools and technologies--including sensor systems, analytic methods, molecular technologies, computational tools, and bioinformatics--have provided the potential for more accurate and comprehensive exposure science data than ever before. This report also provides a roadmap to take advantage of the technologic innovations and strategic collaborations to move exposure science into the future.

Exposed Science

Exposed Science
Author : Sara Shostak
Publisher : Univ of California Press
Release Date : 2013-02-15
Category : Health & Fitness
Total pages :297
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We rely on environmental health scientists to document the presence of chemicals where we live, work, and play and to provide an empirical basis for public policy. In the last decades of the 20th century, environmental health scientists began to shift their focus deep within the human body, and to the molecular level, in order to investigate gene-environment interactions. In Exposed Science, Sara Shostak analyzes the rise of gene-environment interaction in the environmental health sciences and examines its consequences for how we understand and seek to protect population health. Drawing on in-depth interviews and ethnographic observation, Shostak demonstrates that what we know – and what we don’t know – about the vulnerabilities of our bodies to environmental hazards is profoundly shaped by environmental health scientists’ efforts to address the structural vulnerabilities of their field. She then takes up the political effects of this research, both from the perspective of those who seek to establish genomic technologies as a new basis for environmental regulation, and from the perspective of environmental justice activists, who are concerned that that their efforts to redress the social, political, and economical inequalities that put people at risk of environmental exposure will be undermined by molecular explanations of environmental health and illness. Exposed Science thus offers critically important new ways of understanding and engaging with the emergence of gene-environment interaction as a focal concern of environmental health science, policy-making, and activism.

Journal of Exposure Science & Environmental Epidemiology

Journal of Exposure Science & Environmental Epidemiology
Author : Anonim
Publisher : Unknown
Release Date : 2006
Category : Environmental health
Total pages :129
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Using 21st Century Science to Improve Risk-Related Evaluations

Using 21st Century Science to Improve Risk-Related Evaluations
Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Incorporating 21st Century Science into Risk-Based Evaluations
Publisher : National Academies Press
Release Date : 2017-03-16
Category : Nature
Total pages :200
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Over the last decade, several large-scale United States and international programs have been initiated to incorporate advances in molecular and cellular biology, -omics technologies, analytical methods, bioinformatics, and computational tools and methods into the field of toxicology. Similar efforts are being pursued in the field of exposure science with the goals of obtaining more accurate and complete exposure data on individuals and populations for thousands of chemicals over the lifespan; predicting exposures from use data and chemical-property information; and translating exposures between test systems and humans. Using 21st Century Science to Improve Risk-Related Evaluations makes recommendations for integrating new scientific approaches into risk-based evaluations. This study considers the scientific advances that have occurred following the publication of the NRC reports Toxicity Testing in the 21st Century: A Vision and a Strategy and Exposure Science in the 21st Century: A Vision and a Strategy. Given the various ongoing lines of investigation and new data streams that have emerged, this publication proposes how best to integrate and use the emerging results in evaluating chemical risk. Using 21st Century Science to Improve Risk-Related Evaluations considers whether a new paradigm is needed for data validation, how to integrate the divergent data streams, how uncertainty might need to be characterized, and how best to communicate the new approaches so that they are understandable to various stakeholders.

The Practice of Consumer Exposure Assessment

The Practice of Consumer Exposure Assessment
Author : Gerhard Heinemeyer,Matti Jantunen,Pertti Hakkinen
Publisher : Springer Nature
Release Date : 2020-01-03
Category : Medical
Total pages :584
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This book closes a current gap by providing the scientific basis for consumer exposure assessment in the context of regulatory risk assessment. Risk is defined as the likelihood of an event occurring and the severity of its effects. The margin between the dose that leads to toxic effects and the actual dose of a chemical is identified by estimating population exposure. The objective of this book is to provide an introduction into the scientific principles of consumer exposure assessment, and to describe the methods used to estimate doses of chemicals, the statistics applied and computer tools needed. This is presented through the backgrounds of the special fields in exposure analysis, such as exposure via food and by the use of consumer products, toys, clothing and other items. As a general concept, human exposure is also understood to include exposure via the environment and from the work setting. In this context, the specific features of consumer exposure are pointed out and put into the context of regulation, in particular food safety, chemicals safety (REACh) and consumer product safety. The book is structured into three parts: The first part deals with the general concepts of consumer exposure as part of the overall risk analysis framework of risk characterization, risk assessment and risk communication. It describes the three basic features of exposure assessment (i) the exposure scenario (ii) the exposure model and (iii) the exposure parameters, addressing external and internal exposure. Also, the statistical presentation of data to characterize populations, in connection with variability, uncertainty and quality of information and the presentation of exposure evaluation results is described. The second part deals with the specific issues of exposure assessment, exposure via food consumption, exposure from use of consumer products, household products, toys, cosmetic products, textiles, pesticides and others. This part also covers methods for acquisition of data for exposure estimations, including the relevant information from regulations needed to perform an accurate exposure assessment. The third part portrays a prospect for further needs in the development and improvement of consumer exposure assessment, as well as international activities and descriptions of the work of institutions that are involved in exposure assessment on the regulatory and scientific level. And conversely, it creates the rationale for the exposure assessment details necessary to satisfy regulatory needs such as derivation of upper limits and risk management issues.

Textbook of Children's Environmental Health

Textbook of Children's Environmental Health
Author : Philip J. Landrigan,Ruth A. Etzel
Publisher : Oxford University Press
Release Date : 2013-11-15
Category : Medical
Total pages :608
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Over the past four decades, the prevalence of autism, asthma, ADHD, obesity, diabetes, and birth defects have grown substantially among children around the world. Not coincidentally, more than 80,000 new chemicals have been developed and released into the global environment during this same period. Today the World Health Organization attributes 36% of all childhood deaths to environmental causes. Children's environmental health is a new and expanding discipline that studies the profound impact of chemical and environmental hazards on child health. Amid mounting evidence that children are exquisitely sensitive to their environment-and that exposure during their developmental "windows of susceptibility" can trigger cellular changes that lead to disease and disability in infancy, childhood, and across the life span-there is a compelling need for continued scientific study of the relationship between children's health and environment. The Textbook of Children's Environmental Health codifies the knowledge base and offers an authoritative and comprehensive guide to this important new field. Edited by two internationally recognized pioneers in the area, this volume presents up-to-date information on the chemical, biological, physical, and societal hazards that confront children in today's world: pesticides, indoor and outdoor air pollution, lead, arsenic, phthalates, bisphenol A, brominated flame retardants, ionizing radiation, electromagnetic fields, and the built environment. It presents carefully documented data on rising rates of disease in children, offers a critical summary of new research linking pediatric disease with environmental exposures, and explores the cellular, molecular, and epigenetic mechanisms underlying diseases of environmental origin. With this volume's emphasis upon integrating theory and practice, readers will find practical approaches to channeling scientific findings into evidence-based strategies for preventing and identifying the environmental hazards that cause disease in children. It is a landmark work that will serve as the field's benchmark for years to come.

Exposure Analysis

Exposure Analysis
Author : Wayne R. Ott,Anne C. Steinemann,Lance A. Wallace
Publisher : CRC Press
Release Date : 2006-10-26
Category : Science
Total pages :533
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Written by experts, Exposure Analysis is the first complete resource in the emerging scientific discipline of exposure analysis. A comprehensive source on the environmental pollutants that affect human health, the book discusses human exposure through pathways including air, food, water, dermal absorption, and, for children, non-food ingestion. The book summarizes existing definitions of exposure, dose, and related concepts and provides the mathematical framework at the heart of these conceptual definitions. Using secondhand smoke as an example, the book illustrates how exposure analysis studies can change human behavior and improve public health. An extensive section on air pollutants considers volatile organic compounds (VOCs), carbon monoxide (CO), fine and ultrafine particles, and the latest personal air quality monitors for measuring individual exposure. Another detailed section examines exposures to pesticides, metals such as lead, and dioxin that may occur through multiple routes such as air, food, and dust ingestion. The book explores important aspects of dermal exposure such as the absorption of volatile organic compounds while showering or bathing and exposure through multiple carrier media. The authors describe quantitative methods that have been validated for predicting the concentrations in enclosed everyday locations, such as automobiles and rooms of the home. They also discuss existing laws and examine the relationship between exposure and national policies. Defining the new field of exposure analysis, this book provides the basic tools needed to identify sources, understand causes, measure exposures, and develop strategies for improving public health.

Exposure Analysis

Exposure Analysis
Author : Wayne R. Ott,Anne C. Steinemann,Lance A. Wallace
Publisher : CRC Press
Release Date : 2006-10-26
Category : Science
Total pages :533
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Written by experts, Exposure Analysis is the first complete resource in the emerging scientific discipline of exposure analysis. A comprehensive source on the environmental pollutants that affect human health, the book discusses human exposure through pathways including air, food, water, dermal absorption, and, for children, non-food ingestion. The book summarizes existing definitions of exposure, dose, and related concepts and provides the mathematical framework at the heart of these conceptual definitions. Using secondhand smoke as an example, the book illustrates how exposure analysis studies can change human behavior and improve public health. An extensive section on air pollutants considers volatile organic compounds (VOCs), carbon monoxide (CO), fine and ultrafine particles, and the latest personal air quality monitors for measuring individual exposure. Another detailed section examines exposures to pesticides, metals such as lead, and dioxin that may occur through multiple routes such as air, food, and dust ingestion. The book explores important aspects of dermal exposure such as the absorption of volatile organic compounds while showering or bathing and exposure through multiple carrier media. The authors describe quantitative methods that have been validated for predicting the concentrations in enclosed everyday locations, such as automobiles and rooms of the home. They also discuss existing laws and examine the relationship between exposure and national policies. Defining the new field of exposure analysis, this book provides the basic tools needed to identify sources, understand causes, measure exposures, and develop strategies for improving public health.

Issues in General Economic Research and Application: 2011 Edition

Issues in General Economic Research and Application: 2011 Edition
Author : Anonim
Publisher : ScholarlyEditions
Release Date : 2012-01-09
Category : Business & Economics
Total pages :873
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Issues in General Economic Research and Application: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about General Economic Research and Application. The editors have built Issues in General Economic Research and Application: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about General Economic Research and Application in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in General Economic Research and Application: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Science for Environmental Protection

Science for Environmental Protection
Author : National Research Council,Division on Earth and Life Studies,Board on Environmental Studies and Toxicology,Committee on Science for EPA's Future
Publisher : National Academies Press
Release Date : 2012-12-21
Category : Political Science
Total pages :250
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In anticipation of future environmental science and engineering challenges and technologic advances, EPA asked the National Research Council (NRC) to assess the overall capabilities of the agency to develop, obtain, and use the best available scientific and technologic information and tools to meet persistent, emerging, and future mission challenges and opportunities. Although the committee cannot predict with certainty what new environmental problems EPA will face in the next 10 years or more, it worked to identify some of the common drivers and common characteristics of problems that are likely to occur. Tensions inherent to the structure of EPA's work contribute to the current and persistent challenges faced by the agency, and meeting those challenges will require development of leading-edge scientific methods, tools, and technologies, and a more deliberate approach to systems thinking and interdisciplinary science. Science for Environmental Protection: The Road Ahead outlines a framework for building science for environmental protection in the 21st century and identified key areas where enhanced leadership and capacity can strengthen the agency's abilities to address current and emerging environmental challenges as well as take advantage of new tools and technologies to address them. The foundation of EPA science is strong, but the agency needs to continue to address numerous present and future challenges if it is to maintain its science leadership and meet its expanding mandates.

Environmental Health

Environmental Health
Author : Howard Frumkin
Publisher : John Wiley & Sons
Release Date : 2010-01-22
Category : Medical
Total pages :1280
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Environmental Science

Environmental Science
Author : Daniel D. Chiras
Publisher : Jones & Bartlett Learning
Release Date : 2006
Category : Science
Total pages :642
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Completely updated, the seventh edition of 'Environmental Science' enlightens students on the fundamental causes of the current environmental crisis and offers ideas on how we, as a global community, can create a sustainable future.