January 21, 2021

Download Ebook Free Modeling And Simulation In Biomedical Engineering Applications In Cardiorespiratory Physiology

Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology

Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology
Author : Willem van Meurs
Publisher : McGraw Hill Professional
Release Date : 2011-08-07
Category : Technology & Engineering
Total pages :224
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THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all these topics together under one cover and is an important contribution to biomedical literature.” --IEEE Pulse, January 2014 “This book is written by a professional engineer who is unique in that he seems to have a natural understanding of 3 key areas as follows: the hardware involved with simulators, human physiology, and mathematical modeling. Willem van Meurs is one of the inventors of the model-driven human patient simulator (HPS), and so, he is very qualified to write this book. The book is written in a clear way, using the first person throughout, in a conversational manner, with a style that involves posing questions and answering them in subsequent text. ...The book starts with a very useful introduction and background chapter, setting out the scene for the rest of the book. ...I have used his book in enhancing my own talks and understanding human patient simulation and can strongly recommend it.” --Simulation in Healthcare December, 2012 Reviewed by Mark A. Tooley, Ph.D., Department of Medical Physics and Bioengineering, Royal United Hospital, Combe Park, Bath, UK.

A Course in Linear Algebra with Applications

A Course in Linear Algebra with Applications
Author : Derek J S Robinson
Publisher : World Scientific
Release Date : 2006-08-15
Category : Mathematics
Total pages :372
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This is the second edition of the best-selling introduction to linear algebra. Presupposing no knowledge beyond calculus, it provides a thorough treatment of all the basic concepts, such as vector space, linear transformation and inner product. The concept of a quotient space is introduced and related to solutions of linear system of equations, and a simplified treatment of Jordan normal form is given. Numerous applications of linear algebra are described, including systems of linear recurrence relations, systems of linear differential equations, Markov processes, and the Method of Least Squares. An entirely new chapter on linear programing introduces the reader to the simplex algorithm with emphasis on understanding the theory behind it. The book is addressed to students who wish to learn linear algebra, as well as to professionals who need to use the methods of the subject in their own fields.

Mathematical Modelling and Computer Simulation of Activated Sludge Systems

Mathematical Modelling and Computer Simulation of Activated Sludge Systems
Author : Jacek Makinia
Publisher : IWA Publishing
Release Date : 2010
Category : Science
Total pages :389
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This international, comprehensive guide to modeling and simulation studies in activated sludge systems leads the reader through the entire modeling process - from building a mechanistic model to applying the model in practice. Mathematical Modelling and Computer Simulation of Activated Sludge Systems will: * enhance the readers' understanding of different model concepts for several (most essential) biochemical processes in the advanced activated sludge systems, * provide extensive and up-to-date coverage of experimental methodologies of a complete model parameter estimation (longitudinal dispersion coefficient, influent wastewater fractions, kinetic and stoichiometric coefficients, settling velocity, etc.), * summarize and critically review the ranges of model parameters reported in literature, * compare the existing protocols aiming at a systematic organization of the simulation study, * outline the capabilities of the existing commercial simulators, * present documented, successful case studies of practical model applications as a guide while planning a simulation study. The book is organized to provide a general background and some basic definitions, then theoretical aspects of modeling and finally, the issues important for practical model applications. Mathematical Modelling and Computer Simulation of Activated Sludge Systems can be used as supplementary material for a graduate level wastewater engineering courses and is useful to a wide audience of researchers and practitioners. Experienced model users such as consultants, trained plant management staff may find the book useful as a reference and as a resource for self-guided study.

Health Care Systems Engineering for Scientists and Practitioners

Health Care Systems Engineering for Scientists and Practitioners
Author : Andrea Matta,Evren Sahin,Jingshan Li,Alain Guinet,Nico J. Vandaele
Publisher : Springer
Release Date : 2016-09-01
Category : Medical
Total pages :214
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In this volume, scientists and practitioners write about new methods and technologies for improving the operation of health care organizations. Statistical analyses play an important role in these methods with the implications of simulation and modeling applied to the future of health care. Papers are based on work presented at the Second International Conference on Health Care Systems Engineering (HCSE2015) in Lyon, France. The conference was a rare opportunity for scientists and practitioners to share work directly with each other. Each resulting paper received a double blind review. Paper topics include: hospital drug logistics, emergency care, simulation in patient care, and models for home care services.

Introduction To Metabolic And Cellular Engineering, An (Second Edition)

Introduction To Metabolic And Cellular Engineering, An (Second Edition)
Author : Cortassa Sonia Del Carmen,Aon Miguel Antonio,Aon Juan Carlos,Iglesias Alberto Alvaro,Lloyd David
Publisher : World Scientific
Release Date : 2011-12-28
Category : Technology & Engineering
Total pages :448
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Metabolic and Cellular Engineering (MCE) is more than an exciting scientific enterprise. It has become the cornerstone for coping with the challenges ahead of mankind. Continuous developments, new concepts, and technological innovations will enable us to deal with emerging challenges, and solve problems once thought impossible ten years ago. Challenges in MCE are broad- from unraveling fundamental aspects of cellular function to meeting unsatiated energy and food demands that are rising in parallel with population growth.In charting the progress of MCE during the last decade, we could not help but feel in awe of the enormous strides of progress made from the nascent Metabolic Engineering to the Systems Bioengineering of today. The burgeoning availability of genomic sequences from diverse species has been spectacular. It has become the engine that drives the genetic means for the modification of existing organisms and the generation of synthetic, man-made ones. From the initial attempts at purposeful genetic modification of a cell for the production of valuable compounds, we have now moved on to changing microbes genetically or metabolically.The arsenal of experimental and theoretical tools available for Metabolic and Cellular Engineering has expanded enormously, driven by the re-emergence of Physiology as Systems Biology. The revival of the concept of networks fueled by new developments has become central to Systems Biology. Networks represent an integrative vision of how processes of disparate nature relate to each other, and as such is becoming a key analytical and conceptual tool for MCE. This book reflects and addresses all these ongoing changes while providing the essential conceptual and analytical tools needed to understand and work in the MCE research field.

Differential Operators on Spaces of Variable Integrability

Differential Operators on Spaces of Variable Integrability
Author : David E Edmunds,Jan Lang,Osvaldo Méndez
Publisher : World Scientific
Release Date : 2014-06-26
Category : Mathematics
Total pages :224
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The theory of Lebesgue and Sobolev spaces with variable integrability is experiencing a steady expansion, and is the subject of much vigorous research by functional analysts, function-space analysts and specialists in nonlinear analysis. These spaces have attracted attention not only because of their intrinsic mathematical importance as natural, interesting examples of non-rearrangement-invariant function spaces but also in view of their applications, which include the mathematical modeling of electrorheological fluids and image restoration. The main focus of this book is to provide a solid functional-analytic background for the study of differential operators on spaces with variable integrability. It includes some novel stability phenomena which the authors have recently discovered. At the present time, this is the only book which focuses systematically on differential operators on spaces with variable integrability. The authors present a concise, natural introduction to the basic material and steadily move toward differential operators on these spaces, leading the reader quickly to current research topics. Contents:Preliminaries:The Geometry of Banach SpacesSpaces with Variable ExponentSobolev Spaces with Variable Exponent:Definition and Functional-analytic PropertiesSobolev EmbeddingsCompact EmbeddingsRiesz PotentialsPoincaré-type InequalitiesEmbeddingsHölder Spaces with Variable ExponentsCompact Embeddings RevisitedThe p(·)-Laplacian:PreliminariesThe p(·)-LaplacianStability with Respect to IntegrabilityEigenvalues:The Derivative of the ModularCompactness and EigenvaluesModular EigenvaluesStability with Respect to the ExponentConvergence Properties of the EigenfunctionsApproximation on Lp Spaces:s-numbers and n-widthsA Sobolev EmbeddingIntegral Operators Readership: Graduates and researchers interested in differential operators and function spaces. Key Features:Novelty: there is no book covering the principal research topics included in this workExtension: other works give detailed accounts of the basic features of spaces of variable exponents. Our book provides a natural extension to the realm of differential operators on those spacesDepth: new insights are given into differential operators in spaces of variable exponents. In particular, the book will contain novel material on the stability of eigenvalues that has been developed very recentlyKeywords:Lebesgue Spaces with Variable Integrability;Differential Operators;Sobolev Spaces;Eigenvalues;Eigenfunctions

Computational Frameworks

Computational Frameworks
Author : Mamadou Kaba Traore
Publisher : Elsevier
Release Date : 2017-07-07
Category : Computers
Total pages :136
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Computational Frameworks: Systems, Models and Applications provides an overview of advanced perspectives that bridges the gap between frontline research and practical efforts. It is unique in showing the interdisciplinary nature of this area and the way in which it interacts with emerging technologies and techniques. As computational systems are a dominating part of daily lives and a required support for most of the engineering sciences, this book explores their usage (e.g. big data, high performance clusters, databases and information systems, integrated and embedded hardware/software components, smart devices, mobile and pervasive networks, cyber physical systems, etc.). Provides a unique presentation on the views of frontline researchers on computational systems theory and applications in one holistic scope Cover both computational science and engineering Bridges the gap between frontline research and practical efforts

Case For Cases, The: Teaching With Cases - How To Teach Using The Case Method

Case For Cases, The: Teaching With Cases - How To Teach Using The Case Method
Author : Zerrillo Philip
Publisher : World Scientific
Release Date : 2018-08-23
Category : Education
Total pages :108
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This book is intended to support faculty in designing and conducting case teaching. The book is a practical 'how to' guide for faculty setting up and delivering a case based class. It can be used by instructors of all levels as it discusses issues such as class culture, teaching pace, grading, board usage etc.

Nonlinear Dynamic Modeling of Physiological Systems

Nonlinear Dynamic Modeling of Physiological Systems
Author : Professor Vasilis Z. Marmarelis
Publisher : John Wiley & Sons
Release Date : 2004-09-03
Category : Medical
Total pages :541
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The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.

Comprehensive Healthcare Simulation: ECMO Simulation

Comprehensive Healthcare Simulation: ECMO Simulation
Author : Lindsay C. Johnston
Publisher : Springer Nature
Release Date : 2021
Category :
Total pages :129
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Methods of Qualitative Theory in Nonlinear Dynamics

Methods of Qualitative Theory in Nonlinear Dynamics
Author : Leonid P Shilnikov,Andrey L Shilnikov,Dmitry V Turaev,Leon O Chua
Publisher : World Scientific
Release Date : 1998-12-08
Category : Science
Total pages :416
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Bifurcation and Chaos has dominated research in nonlinear dynamics for over two decades and numerous introductory and advanced books have been published on this subject. There remains, however, a dire need for a textbook which provides a pedagogically appealing yet rigorous mathematical bridge between these two disparate levels of exposition. This book is written to serve the above unfulfilled need. Following the footsteps of Poincaré, and the renowned Andronov school of nonlinear oscillations, this book focuses on the qualitative study of high-dimensional nonlinear dynamical systems. Many of the qualitative methods and tools presented in this book were developed only recently and have not yet appeared in a textbook form. In keeping with the self-contained nature of this book, all topics are developed with an introductory background and complete mathematical rigor. Generously illustrated and written with a high level of exposition, this book will appeal to both beginners and advanced students of nonlinear dynamics interested in learning a rigorous mathematical foundation of this fascinating subject. Contents:Basic ConceptsStructurally Stable Equilibrium States of Dynamical SystemsStructurally Stable Periodic Trajectories of Dynamical SystemsInvariant ToriCenter Manifold. Local CaseCenter Manifold. Non-Local Case Readership: Engineers, students, mathematicians and researchers in nonlinear dynamics and dynamical systems. Keywords:Bifurcations;Dynamical Systems;Qualitative Theory;Chaos;Strange Attractors;Nonlinear DynamicsReviews: “It is well-written and clearly organized with excellent figures … This rigorous book, with its emphasis on mathematical technique, would form an excellent basis for an engineering course if supplemented with applications.” Applied Mechanics Reviews “Short remarks concerning various, not only mathematical, aspects of the theory add an extra flavour to the text. I recommend the book for all persons interested in the qualitative theory of differential equations.” Mathematical Reviews

Introduction to the Calculus of Variations

Introduction to the Calculus of Variations
Author : Bernard Dacorogna
Publisher : World Scientific Publishing Company
Release Date : 2014-08-13
Category : Mathematics
Total pages :324
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The calculus of variations is one of the oldest subjects in mathematics, and it is very much alive and still evolving. Besides its mathematical importance and its links to other branches of mathematics, such as geometry or differential equations, it is widely used in physics, engineering, economics and biology. This book serves both as a guide to the expansive existing literature and as an aid to the non-specialist — mathematicians, physicists, engineers, students or researchers — in discovering the subject's most important problems, results and techniques. Despite the aim of addressing non-specialists, mathematical rigor has not been sacrificed; most of the theorems are either fully proved or proved under more stringent conditions. In this new edition, several new exercises have been added. The book, containing a total of 119 exercises with detailed solutions, is well designed for a course at both undergraduate and graduate levels.

Introduction to Coastal Engineering and Management

Introduction to Coastal Engineering and Management
Author : J. William Kamphuis
Publisher : World Scientific
Release Date : 2000
Category : Nature
Total pages :437
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This book is intended to be a text for undergraduate students of coastal engineering. It also serves as a reference for graduate students building on a basic foundation in coastal engineering. Finally, it makes an excellent guide for people in related disciplines. Coastal managers may use the book to cover the more theoretical and engineering-related aspects of their trade. Its subject matter is of interest to geographers, planners and coastal scientists alike.

Multidimensional Hypergeometric Functions and Representation Theory of Lie Algebras and Quantum Groups

Multidimensional Hypergeometric Functions and Representation Theory of Lie Algebras and Quantum Groups
Author : A Varchenko
Publisher : World Scientific
Release Date : 1995-03-29
Category : Mathematics
Total pages :384
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This book recounts the connections between multidimensional hypergeometric functions and representation theory. In 1984, physicists Knizhnik and Zamolodchikov discovered a fundamental differential equation describing correlation functions in conformal field theory. The equation is defined in terms of a Lie algebra. Kohno and Drinfeld found that the monodromy of the differential equation is described in terms of the quantum group associated with the Lie algebra. It turns out that this phenomenon is the tip of the iceberg. The Knizhnik–Zamolodchikov differential equation is solved in multidimensional hypergeometric functions, and the hypergeometric functions yield the connection between the representation theories of Lie algebras and quantum groups. The topics presented in this book are not adequately covered in periodicals. Contents:IntroductionConstruction of Complexes Calculating Homology of the Complement of a ConfigurationConstruction of Homology Complexes for Discriminantal ConfigurationAlgebraic Interpretation of Chain Complexes of a Discriminantal ConfigurationQuasiisomorphism of Two-Sided Hochschild Complexes to Suitable One-Sided Hochschild ComplexesBundle Properties of a Discriminantal ConfigurationR-Matrix for the Two-Sided Hochschild ComplexesMonodromyR-Matrix Operator as the Canonical Element, Quantum DoublesHypergeometric IntegralsKac–Moody Lie Algebras Without Serre's Relations and Their DoublesHypergeometric Integrals of a Discriminantal ConfigurationResonances at InfinityDegenerations of Discriminantal ConfigurationsRemarks on Homology Groups of a Configuration with Coefficients in Local Systems More General than Complex One-Dimensional Readership: Mathematicians, theoretical physicists, and graduate students. keywords:Hypergeometric Function;Hypergeometric Type Function;Hypergeometric Integral;Kac-Moody Algebra;Quantum Group;Representations of a Kac-Moody Algebra;Representations of a Quantum Group;Discriminant Configuration;Monodromy “The book is elegantly structured and sticks closely to the point, and is also fairly down to earth … as well as serving as an excellent specialist monograph, it should also be useful as a first exposure to these topics for anyone who likes to learn a subject through the study of a concrete problem.” Bull. London Math. Soc.

An Introduction to String Theory and D-brane Dynamics

An Introduction to String Theory and D-brane Dynamics
Author : Richard J. Szabo
Publisher : World Scientific
Release Date : 2004
Category : Science
Total pages :128
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This book provides a quick introduction to the rudiments of perturbative string theory and a detailed introduction to the more current topic of D-brane dynamics. The presentation is very pedagogical, with much of the technical detail streamlined. The material is based on mini-courses delivered by the author at various summer schools in theoretical high energy physics.