January 16, 2021

Download Ebook Free From Artemisia Annua L. To Artemisinins

From Artemisia annua L. to Artemisinins

From Artemisia annua L. to Artemisinins
Author : Youyou Tu
Publisher : Academic Press
Release Date : 2017-07-08
Category : Medical
Total pages :468
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From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief inventor of artemisinin, together with other members from the research team, have written a book that will be a valuable reference work for both researchers involved in the medical industry and scholars who are interested in undertaking innovative research. Presents a full view of artemisinin, not only its origin and development, but also chemical structure, chemical properties, extracting mode, derivatives, chromogenic reaction, general pharmacological, and toxicology. Provides many aspects of artemisinin-based drugs Incudes lots of experimental data, such as the X-ray crystallography result—the first application reported in China in determining the absolute molecular configuration utilizing the scattering effects of oxygen atoms by X-ray diffraction technique

Artemisia annua - Pharmacology and Biotechnology

Artemisia annua - Pharmacology and Biotechnology
Author : Tariq Aftab,Jorge F.S. Ferreira,M. Masroor A. Khan,M. Naeem
Publisher : Springer Science & Business Media
Release Date : 2013-11-26
Category : Science
Total pages :292
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Artemisinin, a sesquiterpene lactone originally extracted from the medicinal plant Artemisia annua L., is an effective antimalarial agent, particularly for multi-drug resistant and cerebral malaria. However, the concentration of artemisinin in the plant is very low. Because the chemical synthesis of artemisinin is complicated and not economically feasible in view of the poor yield of the drug, the intact plant remains the only viable source of artemisinin production. Therefore, it is necessary to increase the concentration of artemisinin in A. annua to reduce the cost of artemisinin based antimalarial drugs. Plant scientists have focused their efforts on A. annua for a higher artemisinin crop yield. With the present volume, we are bringing together the research which is being done on this plant throughout the world and future possibilities for scientists and researchers who want to work on it.

Medicinal and Aromatic Plants XII

Medicinal and Aromatic Plants XII
Author : Toshiyuki Nagata,Yutaka Ebizuka
Publisher : Springer Science & Business Media
Release Date : 2013-11-11
Category : Science
Total pages :348
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Medicinal and Aromatic Plants XII comprises 18 chapters. It deals with the distribution, importance, conventional propagation, micropropagation, tissue culture studies, and the in vitro production of important medicinal and pharmaceutical compounds in the following plants: Artemisia annua, Coriandrum sativum, Crataegus, Dionaea muscipula, Hyoscyamus reticulatus, Hypericum canariense, Leguminosae, Malva, Ocimum, Pergularia tomentosa, Phellodendron amurense, Sempervivum, Solanum aculeatissimum, S. chrysotrichum, S. kasianum, Stephania, Trigonella, and Vaccinium. It is tailored to the needs of advanced students, teachers, and research scientists in the fields of pharmacy, plant tissue culture, phytochemistry, biomedical engineering, and plant biotechnology in general.

Artemisia annua

Artemisia annua
Author : Tariq Aftab,M. Naeem,M. Masroor A. Khan
Publisher : CRC Press
Release Date : 2017-12-14
Category : Health & Fitness
Total pages :340
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Artemisia annua is a well-known medicinal plant that has been utilized for a number of purposes, including malaria, for centuries. This is the first comprehensive book to cover the importance of Artemisia annua in the global health crisis and in the treatment against diseases. A component and extract, artemisinin, is the source of other derivatives which are also suitable for pharmaceutical use. The present demand for artemisinin far outpaces its supply. Researchers are working globally towards improving artemisinin content in the plant by various means. Artemisia annua: Prospects, Applications and Therapeutic Uses highlights the different approaches, including ‘omics', that are being used in current research on this immensely important medicinal plant. Providing comprehensive coverage of the agricultural and pharmaceutical uses of this plant, Artemisia annua will be essential reading for botanists, plant scientists, herbalists, pharmacognosists, pharmacologists and natural product chemists.

Artemisinin-Based and Other Antimalarials

Artemisinin-Based and Other Antimalarials
Author : Guoqiao Li,Ying Li,Zelin Li,Meiyi Zeng
Publisher : Academic Press
Release Date : 2017-11-28
Category : Medical
Total pages :736
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Artemisinin-Based and Other Antimalarials: Detailed Account of Studies by Chinese Scientists Who Discovered and Developed Them provides a historical and scientific background of the discovery and development of artemisinin, artemisinin derivatives, combination drugs and related chemicals. It is a historical document, a scientific treatise, and a fascinating description of innovative research on new drug development that is carried out under extremely difficult conditions. The book also includes detailed experiments, physical-chemical procedures, practical methodologies and clinical trials. It is a valuable reference for students and researchers in the fields of scientific history, medicine, pharmaceutical science, chemistry, pharmacology and toxicology. Presents details of all stages of drug development, including in vitro experiment, animal exploratory studies, animal tests for toxicity, safety and efficacy followed by stages I, II, III and IV, safety and efficacy in human volunteers and patients with malaria Provides many physical-chemical laboratory procedures, such as NMR, MS, HPLC and X-ray diffraction used in drug development Includes practical methodology of clinical trials from many research centers and countries to demonstrate the importance of this discovery

Artemisinin - From Traditional Chinese Medicine to Artemisinin Combination Therapies; Four Decades of Research on the Biochemistry,Physiology, and Breeding of Artemisia annua

Artemisinin - From Traditional Chinese Medicine to Artemisinin Combination Therapies; Four Decades of Research on the Biochemistry,Physiology, and Breeding of Artemisia annua
Author : Tomasz Czechowski,Ian A. Graham,Pamela J. Weathers,Peter E. Brodelius,Geoffrey Duncan Brown
Publisher : Frontiers Media SA
Release Date : 2020-12-04
Category : Science
Total pages :129
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Artemisia annua

Artemisia annua
Author : Tariq Aftab,M. Naeem,M. Masroor A. Khan
Publisher : CRC Press
Release Date : 2017-12-14
Category : Health & Fitness
Total pages :340
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Artemisia annua is a well-known medicinal plant that has been utilized for a number of purposes, including malaria, for centuries. This is the first comprehensive book to cover the importance of Artemisia annua in the global health crisis and in the treatment against diseases. A component and extract, artemisinin, is the source of other derivatives which are also suitable for pharmaceutical use. The present demand for artemisinin far outpaces its supply. Researchers are working globally towards improving artemisinin content in the plant by various means. Artemisia annua: Prospects, Applications and Therapeutic Uses highlights the different approaches, including ‘omics', that are being used in current research on this immensely important medicinal plant. Providing comprehensive coverage of the agricultural and pharmaceutical uses of this plant, Artemisia annua will be essential reading for botanists, plant scientists, herbalists, pharmacognosists, pharmacologists and natural product chemists.

Artemisia

Artemisia
Author : Colin W. Wright
Publisher : CRC Press
Release Date : 2001-10-18
Category : Science
Total pages :344
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A comprehensive overview of this genus, Artemisia examines all aspects of the herbs uses and applications, its mode of action and clinical importance. Following a comprehensive introduction to the genus, the book discusses the botanical, phytochemical and biological aspects of a number of important species of Artemisis. Considering that the discove

A Detailed Chronological Record of Project 523 and the Discovery and Development of Qinghaosu (Artemisinin)

A Detailed Chronological Record of Project 523 and the Discovery and Development of Qinghaosu (Artemisinin)
Author : Zhang Jianfang
Publisher : Strategic Book Publishing
Release Date : 2013-02
Category : Science
Total pages :206
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This is an account of a project in China carried out in secrecy from the Chinese people and the Western World during the tumultuous years of the Cultural Revolution. Project 523, as it was called, resulted in one of the most significant advances in the treatment of malaria since the discovery and first use of quinine over 300 years ago. The origin of the project was a request from the North Vietnamese Government to Mao Zedong in China, for assistance in managing chloroquine drug-resistant malaria affecting their military forces during the Vietnam-American war. Initially the project was directed by the Chinese military medical research authorities, but it became so large that civilian scientists were called upon to help. Ultimately, to accomplish this task, over 60 institutions and more than 500 scientists and other personnel scattered throughout mainland China became involved. This achievement is all the more remarkable because it was accomplished during the Cultural Revolution using obsolete equipment, and at a time when all regular research was halted, scientists were harassed and denigrated, and academic and intellectual activity was discouraged or even forbidden. The drug discovered - artemisinin from the plant Qinghao (Artemisia annua L) - is now the most widely used treatment for malaria in the world.

WHO Monograph on Good Agricultural and Collection Practices (GACP) for Artemisia Annua L.

WHO Monograph on Good Agricultural and Collection Practices (GACP) for Artemisia Annua L.
Author : Anonim
Publisher : Unknown
Release Date : 2006
Category : Antimalarials
Total pages :49
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Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants

Recent Trends in Biotechnology and Therapeutic Applications of Medicinal Plants
Author : Mohd. Shahid,Anwar Shahzad,Abida Malik,Aastha Sahai
Publisher : Springer Science & Business Media
Release Date : 2013-05-13
Category : Science
Total pages :357
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The book provides an overview of current trends in biotechnology and medicinal plant sciences. The work includes detailed chapters on various advance biotechnological tools involved in production of phytoactive compounds of medicinal significance. Some recent and novel research studies on therapeutic applications of different medicinal plants from various geographical regions of the world have also been included. These studies report the antimicrobial activity of various natural plant products against various pathogenic microbial strains. Informative chapters on recent emerging applications of plant products such as source for nutraceuticals and vaccines have been integrated to cover latest advances in the field. This book also explores the conservation aspect of medicinal plants. Thus, chapters having comprehensively complied in vitro conservation protocols for various commercially important rare, threatened and endangered medicinal plants were provided in the present book.

Approaches to Design and Synthesis of Antiparasitic Drugs

Approaches to Design and Synthesis of Antiparasitic Drugs
Author : N. Anand,S. Sharma†
Publisher : Elsevier
Release Date : 1997-07-10
Category : Medical
Total pages :510
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This book presents a comprehensive and up to date account of the chemotherapy of parasitic diseases, both human and veterinary. The book starts with an overview of parasitic diseases. The body of the book is divided into two parts: antihelminthic drugs, and antiprotozoal drugs. Both parts start with chapters highlighting the 'biochemical targets' available for chemotherapeutic interference. Individual chapters deal with one chemical class of compounds and describe their origin, structure-activity relationship, mode of action, and methods of synthesis and their status both in clinical and veterinary practice. The book will be useful to a wide spectrum of readers: students embarking on a research career in parasitic chemotherapy, clinicians (and veterinarians) and clinical pharmacologists desiring detailed information about the drugs currently in use, and pharmaceutical technologists wanting to update their knowledge of the methods of manufacture.

Herbal Drugs: Ethnomedicine to Modern Medicine

Herbal Drugs: Ethnomedicine to Modern Medicine
Author : Kishan Gopal Ramawat
Publisher : Springer Science & Business Media
Release Date : 2008-11-25
Category : Science
Total pages :402
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Considerable progress has been made in our healthcare system, in particular with respect to sensitive diagnostic tools, reagents and very effective and precise drugs. On the other hand, high-throughput screening technology can screen vast numbers of compounds against an array of targets in a very short time, and leads thus - tained can be further explored. In developing countries, the exploding population exerts pressure not only on natural resources but also on the human population - self, whose members strive to become successful and advance in society. This leads to increased blood pressure, anxiety, obesity-associated lipid disorders, cardiov- cular diseases and diabetes. Most of these diseases result in disturbed family life, including sexual behaviour. Despite technological developments, herbal drugs still occupy a preferential place in a majority of the population in the Third World and terminal patients in the West. Herbal drugs, in addition to being cost effective and easily accessible, have been used since time immemorial and have passed the test of time without having any side effects. The multitarget effects of herbs (holistic approaches) are the fun- mental basis of their utilization. This approach is already used in traditional systems of medicine like Ayurveda, which has become more popular in the West in recent years. However, the integration of modern science with traditional uses of herbal drugs is of the utmost importance if ones wishes to use ancient knowledge for the betterment of humanity.

Atti Della Fondazione Giorgio Ronchi Anno LXIV N.5

Atti Della Fondazione Giorgio Ronchi Anno LXIV N.5
Author : Anonim
Publisher : Lucia Ronchi
Release Date : 2021
Category :
Total pages :129
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Medicinal Plants and Environmental Challenges

Medicinal Plants and Environmental Challenges
Author : Mansour Ghorbanpour,Ajit Varma
Publisher : Springer
Release Date : 2017-10-31
Category : Medical
Total pages :413
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This book sheds new light on the role of various environmental factors in regulating the metabolic adaptation of medicinal and aromatic plants. Many of the chapters present cutting-edge findings on the contamination of medicinal plants through horizontal transfer, as well as nanomaterials and the biosynthesis of pharmacologically active compounds. In addition, the book highlights the impacts of environmental factors (e.g., high and low temperature, climate change, global warming, UV irradiation, intense sunlight and shade, ozone, carbon dioxide, drought, salinity, nutrient deficiency, agrochemicals, waste, heavy metals, nanomaterials, weeds, pests and pathogen infections) on medicinal and aromatic plants, emphasizing secondary metabolisms. In recent years, interest has grown in the use of bioactive compounds from natural sources. Medicinal and aromatic plants constitute an important part of the natural environment and agro-ecosystems, and contain a wealth of chemical compounds known as secondary metabolites and including alkaloids, glycosides, essential oils and other miscellaneous active substances. These metabolites help plants cope with environmental and/or external stimuli in a rapid, reversible and ecologically meaningful manner. Additionally, environmental factors play a crucial role in regulating the metabolic yield of these biologically active molecules. Understanding how medicinal plants respond to environmental perturbations and climate change could open new frontiers in plant production and in agriculture, where successive innovation is urgently needed due to the looming challenges in connection with global food security and climate change. Readers will discover a range of revealing perspectives and the latest research on this vital topic.