November 24, 2020

Download Ebook Free Handbook Of Polymer Applications In Medicine And Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : Kayvon Modjarrad,Sina Ebnesajjad
Publisher : Elsevier
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

While the prevalence of plastics and elastomers in medical devices is now quite well known, there is less information available covering the use of medical devices and the applications of polymers beyond medical devices, such as in hydrogels, biopolymers and silicones beyond enhancement applications, and few books in which these are combined into a single reference. This book is a comprehensive reference source, bringing together a number of key medical polymer topics in one place for a broad audience of engineers and scientists, especially those currently developing new medical devices or seeking more information about current and future applications. In addition to a broad range of applications, the book also covers clinical outcomes and complications arising from the use of the polymers in the body, giving engineers a vital insight into the real world implications of the devices they’re creating. Regulatory issues are also covered in detail. The book also presents the latest developments on the use of polymers in medicine and development of nano-scale devices. Gathers discussions of a large number of applications of polymers in medicine in one place Provides an insight into both the legal and clinical implications of device design Relevant to industry, academic and medical professionals Presents the latest developments in the field, including medical devices on a nano-scale

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : Kayvon Modjarrad
Publisher : Elsevier Inc. Chapters
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

The history of plastics and medical devices traces a complex course of slowly evolving ideas punctuated by moments of intellectual revolution. When viewed from the vantage of retrospect, it becomes apparent that milestones in the progress of biomaterial science represent culminations of gradual shifts in theory and iterative experimentation. This has been as true for methodological developments in polymer chemistry as it has for technological breakthroughs in medical equipment design. The two disciplines, though now inextricable from one another, initially advanced along largely separate and occasionally redundant paths. Until the latter decades of the twentieth century, physicians and surgeons modified existing materials to create and refine devices according to their clinical needs while chemists and engineers synthesized materials de novo without specific attention to their potential medical applications. In the modern era, however, the lines between the chemical and biological sciences have blurred, paving way for an interdisciplinary approach toward the design and application of medical plastics.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : André Colas,Jim Curtis
Publisher : Elsevier Inc. Chapters
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

Silicone materials have been widely used in medicine for over 60 years. Available in a variety of material types, they have unique chemical and physical properties that manifest in excellent biocompatibility and biodurability for many applications. Silicone elastomers have remarkably low glass-transition temperatures and maintain their flexibility over a wide temperature range, enabling them to withstand conditions from cold storage to steam autoclaving. They have high permeability to gases and many drugs, advantageous respectively in wound care or in transdermal drug delivery. They have low surface tension and remarkable chemical stability, enabling biocompatibility and biodurability in many long-term implant applications.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : Zheng Zhang,Ophir Ortiz,Ritu Goyal,Joachim Kohn
Publisher : Elsevier Inc. Chapters
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

The design and development of tissue-engineered products has benefited from many years of clinical utilization of a wide range of biodegradable polymers. Newly developed biodegradable polymers and modifications of previously developed biodegradable polymers have enhanced the tools available for creating clinically important tissue-engineering applications. Insights gained from studies of cell-matrix interactions, cell-cell signaling, and organization of cellular components, are placing increased demands on medical implants to interact with the patient’s tissue in a more biologically appropriate fashion. Whereas in the twentieth century biocompatibility was largely equated with eliciting no harmful response, the biomaterials of the twenty first century will have to elicit tissue responses that support healing or regeneration of the patient’s own tissue. This chapter surveys the universe of those biodegradable polymers that may be useful in the development of medical implants and tissue-engineered products. Here, we distinguish between biologically derived polymers and synthetic polymers. The materials are described in terms of their chemical composition, breakdown products, mechanism of breakdown, mechanical properties, and clinical limitations. Also discussed are product design considerations in processing of biomaterials into a final form (e.g., gel, membrane, matrix) that will effect the desired tissue response.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : Steven M. Kurtz
Publisher : Elsevier Inc. Chapters
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

The orthopedic and biomaterials literature of the 1990s reflects an early academic curiosity in implant applications of polyaryletherketone (PAEK) biomaterials [1,2]. However, widespread commercial applications for PAEK biomaterials in the human body were first realized with cage implants intended to promote intervertebral body (interbody) fusion of the lumbar spine. Success of PAEK with interbody implants would later inspire applications in a broad variety of spinal implant applications, including posterior fusion, dynamic stabilization, and disc arthroplasty.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : Len Czuba
Publisher : Elsevier Inc. Chapters
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

This chapter will present a look at the medical device market with a particular focus on the materials of construction of devices and what we can expect in new products looking ahead. A deeper look at some other trends that have an effect on the direction of the medical device industry will be done. Finally, consideration will be given to a number of global factors that can have dramatic effects on our industry.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : Vinny R. Sastri
Publisher : Elsevier Inc. Chapters
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

Over the past 2000 years, many devices have been developed and used in the mitigation and diagnosis of diseases. The materials used in these devices have ranged from stone, wood, metal, ceramics, and most recently plastics. Medical devices have also evolved in sophistication and complexity over time. With the formalization of the scientific method in the seventeenth century such devices became more prevalent [1]. Many medical devices were manufactured by doctors or small companies and sold directly to the public with no government standards or oversight. With the explosion of medical technology in the early twentieth century, several intermediaries had evolved between the medical device industry and the public. In 1879, Dr E.R. Squibb, in an address to the Medical Society of the State of New York, proposed the enactment of a national statute to regulate food and drugs [2]. It was not until 27 years later that the Food and Drug Act of 1906 was introduced into the Congress and signed into law by President Theodore Roosevelt [3]. At that time, devices that were harmful to human safety and health proliferated the market but regulation of medical devices by the Bureau of Chemistry (the precursor to the Food and Drug Administration—FDA) was limited to challenging commercial products only after they had been released into the market. Devices in the marketplace that were defective, adulterated, or misbranded were seized and the device manufacturers were prosecuted in a court of law, but only after the products were sold in the market and caused harm to the end users. Thus, there was a strong need for regulating the devices before they entered the marketplace. An FDA report [4], issued in September 1970, detailed as many as 10,000 injuries and 731 deaths from ineffective medical devices. The report recommended the formation of a regulatory system and body that would enforce the production and sale of safe and effective devices to the public. All medical devices already on the market would be inventoried and classified into a three-tiered system based on their criticality of end use. It also detailed requirements for records and reports, registration and inspection of establishments, and uniform quality assurance programs called good manufacturing practices (GMP). After much lobbying by the FDA, Senate bill SR 510, “The Medical Device Amendments of 1973” was introduced by Senator Edward M. Kennedy and was passed by the Senate in 1975. House bill HR 11124, introduced by Representative Paul Rogers, was passed by the House in 1976. These bills eventually became the Medical Device Amendments of 1976, and were signed into law by President Nixon. The Medical Device Amendments of 1976 became the basis for the medical device regulation in the United States to control and regulate the production of finished devices and thus the device manufacturers themselves.

Handbook of Polymer Applications in Medicine and Medical Devices

Handbook of Polymer Applications in Medicine and Medical Devices
Author : Laurence W. McKeen
Publisher : Elsevier Inc. Chapters
Release Date : 2013-12-05
Category : Technology & Engineering
Total pages :368
GET BOOK

Medical devices range from simple devices, to test equipment, to implants. Plastics are used more and more in these devices, for weight, cost, and performance purposes. Examples of medical devices include surgical instruments, catheters, coronary stents, pacemakers, magnetic resonance imaging (MRI) machines, X-ray machines, prosthetic limbs, artificial hips/knees, surgical gloves, and bandages.

Plastics in Medical Devices

Plastics in Medical Devices
Author : Vinny R. Sastri
Publisher : Elsevier
Release Date : 2010-03-05
Category : Technology & Engineering
Total pages :352
GET BOOK

No book has been published that gives a detailed description of all the types of plastic materials used in medical devices, the unique requirements that the materials need to comply with and the ways standard plastics can be modified to meet such needs. This book will start with an introduction to medical devices, their classification and some of the regulations (both US and global) that affect their design, production and sale. A couple of chapters will focus on all the requirements that plastics need to meet for medical device applications. The subsequent chapters describe the various types of plastic materials, their properties profiles, the advantages and disadvantages for medical device applications, the techniques by which their properties can be enhanced, and real-world examples of their use. Comparative tables will allow readers to find the right classes of materials suitable for their applications or new product development needs.

The Medical Device R&D Handbook, Second Edition

The Medical Device R&D Handbook, Second Edition
Author : Theodore R. Kucklick
Publisher : CRC Press
Release Date : 2012-12-05
Category : Medical
Total pages :510
GET BOOK

Exploring the practical, entrepreneurial, and historical aspects of medical device development, this second edition of The Medical Device R&D Handbook provides a how-to guide for medical device product development. The book offers knowledge of practical skills such as prototyping, plastics selection, and catheter construction, allowing designers to apply these specialized techniques for greater innovation and time saving. The author discusses the historical background of various technologies, helping readers understand how and why certain devices were developed. The text also contains interviews with leaders in the industry who offer their vast experience and insights on how to start and grow successful companies—both what works and what doesn’t work. This updated and expanded edition adds new information to help meet the challenges of the medical device industry, including strategic intellectual property management, operating room observation protocol, and the use of new technologies and new materials in device development.

Advanced Polymers in Medicine

Advanced Polymers in Medicine
Author : Francesco Puoci
Publisher : Springer
Release Date : 2014-12-02
Category : Technology & Engineering
Total pages :537
GET BOOK

The book provides an up-to-date overview of the diverse medical applications of advanced polymers. The book opens by presenting important background information on polymer chemistry and physicochemical characterization of polymers. This serves as essential scientific support for the subsequent chapters, each of which is devoted to the applications of polymers in a particular medical specialty. The coverage is broad, encompassing orthopedics, ophthalmology, tissue engineering, surgery, dentistry, oncology, drug delivery, nephrology, wound dressing and healing, and cardiology. The development of polymers that enhance the biocompatibility of blood-contacting medical devices and the incorporation of polymers within biosensors are also addressed. This book is an excellent guide to the recent advances in polymeric biomaterials and bridges the gap between the research literature and standard textbooks on the applications of polymers in medicine.

Handbook of Active Materials for Medical Devices

Handbook of Active Materials for Medical Devices
Author : Andres Diaz Lantada
Publisher : CRC Press
Release Date : 2011-09-28
Category : Technology & Engineering
Total pages :350
GET BOOK

This book covers biodevices, mainly implantable or quirurgical, for the diagnosis or treatment of different pathologies, which benefit from the use of active materials as sensors or actuators. Such active or "intelligent" materials are capable of responding in a controlled way to different external physical or chemical stimuli by changing some of their properties. These materials can be used to design and develop sensors, actuators, and multifunctional systems with a large number of applications for developing biodevices and medical appliances. Current work on these fields entails problems related to synthesis, characterization, modeling, simulation, processing, and prototyping technologies, as well as device testing and validation, all of which are treated in depth in this book, for the several types of active or intelligent materials covered. The research presented in this book helps further development of medical devices, based on the additional functionalities that the use of active or "intelligent" materials, both as sensors and actuators, supplies. The main results exposed may help with the industrial expansion of this kind of materials as part of more complex systems.

Handbook of Polymers in Electronics

Handbook of Polymers in Electronics
Author : Bansi D. Malhotra
Publisher : iSmithers Rapra Publishing
Release Date : 2001-12-31
Category : Electronics
Total pages :474
GET BOOK

The Handbook of Polymers in Electronics has been designed to discuss the novel ways in which polymers can be used in the rapidly growing electronics industry. It provides discussion of the preparation and characterisation of suitable polymeric materials and their current and potential applications coupled with the fundamentals of electrical, optical and photophysical properties. It will thus serve the needs of those already active in the electronics field as well as new entrants to the industry.

Handbook of Biodegradable Polymers

Handbook of Biodegradable Polymers
Author : Abraham J. Domb,Joseph Kost,David Wiseman
Publisher : CRC Press
Release Date : 1998-02-04
Category : Technology & Engineering
Total pages :544
GET BOOK

Handbook of Biodegradable Polymers, the seventh volume in the Drug Delivery and Targeting book series, provides a source manual for synthetic procedures, properties and applications of bioerodible polymers. The authors describe widely available materials such as polyactides, collagen and gelatin, as well as polymers of emerging importance, such as the genetically-engineered and elastin-based polymers which are either proprietary or in early stages of development. Section I addresses synthetic absorbable polymers, and Section 2 profiles natural, semi-synthetic and biosynthetic polymers. Section 3 discusses the surface characterization of degradable polymers, the modeling of biodegradation and non-medical polymers. This book is ideal for researchers from academia and industry as well as chemists, pharmacists and physicians who deal with biopolymers, drug delivery and targeting, bioengineering and implantable devices.

Handbook of Active Materials for Medical Devices

Handbook of Active Materials for Medical Devices
Author : Andres Diaz Lantada
Publisher : CRC Press
Release Date : 2011-09-28
Category : Technology & Engineering
Total pages :350
GET BOOK

This book covers biodevices, mainly implantable or quirurgical, for the diagnosis or treatment of different pathologies, which benefit from the use of active materials as sensors or actuators. Such active or "intelligent" materials are capable of responding in a controlled way to different external physical or chemical stimuli by changing some of their properties. These materials can be used to design and develop sensors, actuators, and multifunctional systems with a large number of applications for developing biodevices and medical appliances. Current work on these fields entails problems related to synthesis, characterization, modeling, simulation, processing, and prototyping technologies, as well as device testing and validation, all of which are treated in depth in this book, for the several types of active or intelligent materials covered. The research presented in this book helps further development of medical devices, based on the additional functionalities that the use of active or "intelligent" materials, both as sensors and actuators, supplies. The main results exposed may help with the industrial expansion of this kind of materials as part of more complex systems.