Download Ebook Free Handbook Of Process Chromatography
Handbook of Process Chromatography
Publisher : Elsevier
Release Date : 2007-12-08
Category : Science
Total pages :382
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This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers. Updates include: - sources and productivity - types of products made today - experiences in clinical and licensed products - economics - current status of validation - illustrations and tables - automated column packing - automated systems New topics include: - the use of disposables - multiproduct versus dedicated production - design principles for chromatography media and filters - ultrafiltration principles and optimization - risk assessments - characterization studies - design space - platform technologies - process analytical technologies (PATs) - biogenerics - comparability assessments Key Features: - new approaches to process optimiaztion - use of patform technologies - applying risk assessment to process design
Handbook of Process Chromatography
Publisher : Academic Press
Release Date : 1997-07-08
Category : Science
Total pages :387
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With examples from companies with establised processes and approved biotherapeutics, this pack considers the entire scope of process chromatography, including scale-up, regulatory issues, equipment, evaluation studies, scheduling and cost effectiveness.
Handbook of Separation Process Technology
Publisher : John Wiley & Sons
Release Date : 1987-05-13
Category : Technology & Engineering
Total pages :1024
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Surveys the selection, design, and operation of most of the industrially important separation processes. Discusses the underlying principles on which the processes are based, and provides illustrative examples of the use of the processes in a modern context. Features thorough treatment of newer separation processes based on membranes, adsorption, chromatography, ion exchange, and chemical complexation. Includes a review of historically important separation processes such as distillation, absorption, extraction, leaching, and crystallization and considers these techniques in light of recent developments affecting them.
Handbook of Process Stream Analysis
Publisher : Ellis Horwood
Release Date : 1974
Category : Analisis instrumental
Total pages :470
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Handbook of Bioseparations
Publisher : Elsevier
Release Date : 2000-06-23
Category : Science
Total pages :722
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It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories. Key Features * Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies * Encompasses both analytical and process-scale methods * Elucidates the importance of engineering process control * Details selection of plant and process equipment * Addresses economic considerations * Discusses future developments
Handbook of Biogeneric Therapeutic Proteins
Publisher : CRC Press
Release Date : 2002-08-15
Category : Medical
Total pages :584
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More than 20 billion dollars worth of biopharmaceuticals are scheduled to go off-patent by 2006. Given the strong political impetus and the development of technological tools that can answer the questions regulatory authorities may raise, it is inevitable that the FDA and EMEA will allow biogeneric or biosimilar products. Even with all the regulato
Purification of Alpha-1-antitrypsin Using a Three-step Chromatography Process
Publisher : Unknown
Release Date : 2003
Category :
Total pages :346
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Handbook of Methods and Instrumentation in Separation Science
Publisher : Academic Press
Release Date : 2009-11-11
Category : Science
Total pages :880
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Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. One-stop source for information on separation methods General overviews for quick orientation Ease of use for finding results fast Expert coverage of major separation methods Coverage of techniques for all sizes of samples, pico-level to kilo-level
Handbook Of Size Exclusion Chromatography And Related Techniques
Publisher : CRC Press
Release Date : 2003-11-04
Category : Science
Total pages :716
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Documenting critical advances in this rapidly evolving field, the Second Edition highlights the need for new applications and technologies that assist in the determination of molecular weight and molecular weight distributions of polymers in an accurate, efficient manner. This volume presents the latest findings from a international team of specialists and continues to inspire and extend practical applications of size exclusion chromatography (SEC). It includes six new chapters covering high-speed size exclusion chromatography, SEC of low molecular weight materials, and the extended family of techniques, from two-dimensional liquid chromatography to high osmotic pressure chromatography.
Process Instruments and Controls Handbook
Publisher : McGraw-Hill Companies
Release Date : 1985
Category : Automatic control
Total pages :1766
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A major revision of a best-selling guide covers the design and operation of measurement and automatic control systems used in such industries as chemical, petroleum, petrochemical, food, pulp and paper, textile, water and wastes, metallurgical and product manufacturing. Reflects new developments in manufacturing industries and in associated research and quality control laboratories.
CRC Handbook of Chromatography
Publisher : CRC Press
Release Date : 1987-06-30
Category : Medical
Total pages :304
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This handbook provides a comprehensive review of the most current developments in nucleic acid research by leading scientists worldwide. Chapters focus on structure elucidation methods, fundamentals of HPLC; analysis of nucleic acids and oligonucleotides; analysis of polynucleotides, nucleotides, nucleosides and bases; nucleic acid components in biological fluids and their diagnostic value; and miscellaneous application. The format is organized according to chromatographic techniques and by chemical classifications. Each subject is presented in the form of a critical review.
Journal of Chromatography
Publisher : Unknown
Release Date : 2003
Category : Chromatographic analysis
Total pages :129
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Handbook of Advanced Process Control Systems and Instrumentation
Publisher : Gulf Publishing Company
Release Date : 1987
Category : Technology & Engineering
Total pages :355
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A Practical Handbook of Preparative HPLC
Publisher : Elsevier
Release Date : 2011-04-18
Category : Technology & Engineering
Total pages :176
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This book is a distillation of twenty years of practical experience of the high pressure liquid chromatography (HPLC) process. Deliberately steering clear of complex theoretical aspects, this book concentrates on the everyday problems associated with the technique, making it perfect for frequent use in the laboratory and for those in the pharmaceutical, agrochemical and biotechnology industries for the analysis and purification of drugs, small molecules, proteins and DNA. This book... •Provides practical, hands-on advice based on years of experience •Will help ensure optimal design, equipment and separation results for your particular task •Presents system layouts from laboratory to process scale •Will help you to devise or improve record-keeping and documentation systems ·Provides practical, hands-on advice based on years of experience ·Will help ensure optimal design, equipment and separation results for your particular task ·Presents system layouts from laboratory to process scale ·Will help you to devise or improve record-keeping and documentation systems
Handbook of ion chromatography
Publisher : Unknown
Release Date : 2004
Category : Chromatographic analysis
Total pages :894
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