December 1, 2020

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Hydroxyapatite (HAp) for Biomedical Applications

Hydroxyapatite (HAp) for Biomedical Applications
Author : Michael Mucalo
Publisher : Elsevier
Release Date : 2015-03-06
Category : Technology & Engineering
Total pages :404
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Hydroxyapatite in the form of hydroxycarbonate apatite is the principal mineral component of bone tissue in mammals. In Bioceramics, it is classed as a bioactive material, which means bone tissue grows directly on it when placed in apposition without intervening fibrous tissue. Hydroxyapatite is hence commonly used as bone grafts, fillers and as coatings for metal implants. This important book provides an overview of the most recent research and developments involving hydroxyapatite as a key material in medicine and its application. Reviews the important properties of hydroxyapatite as a biomaterial Considers a range of specific forms of the material and their advantages Reviews a range of specific medical applications for this important material

Hydroxyapatite (HAp) for Biomedical Applications

Hydroxyapatite (HAp) for Biomedical Applications
Author : Michael Mucalo
Publisher : Woodhead Publishing Limited
Release Date : 2021-07
Category :
Total pages :129
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Hydroxyapatite

Hydroxyapatite
Author : Jagannathan Thirumalai
Publisher : BoD – Books on Demand
Release Date : 2018-02-14
Category : Science
Total pages :186
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The goal of this book is to provide readers with a broad appraisal of topics in global advancements in theoretical and experimental facts, and practical applications of nano-HAp materials based on their synthesis, properties, prospects, and potential biomedical treatments. The perspective of this book involves the preparation of crystalline nano-HAP materials including preferential orientation, various properties and new prospects in biomimetics, bone tissue infections, biomedical implants, regenerative medicinal treatments and a wide range of technological applications. This book is categorized into two main sections: Hydroxyapatite: synthesis, properties, perspectives, and prospects; and the application of hydroxyapatite: a synergistic outlook. Individual chapters provide a base for a wide range of readers from diversified fields, including students and researchers, who will find in this book simply explained basics as well as advanced techniques of specific subjects related to these phenomena. The book is made up of nine contributions, compiled by experts from wide-ranging fields involved in biomaterials/materials in science and technology from over 15 research institutes across the globe.

Hydroxyapatite/titanium Composite Coating for Biomedical Applications

Hydroxyapatite/titanium Composite Coating for Biomedical Applications
Author : Anonim
Publisher : Unknown
Release Date : 2012
Category : Biomedical engineering
Total pages :152
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Hydroxyapatite, (HAP), a calcium phosphate bioceramic material, has been widely used in both dentistry and orthopedics due to its biocompatibility and osteoconductivity. However, its poor bulk mechanical properties have limited its use as load bearing material. An effective approach to solve this problem is to form a composite coating of HAP and titanium, in which titanium will be the matrix and HAP will act as reinforcement. In this research, two novel approaches, namely cold gas dynamic spraying (CGDS) and argon atmosphere plasma spraying (AAPS), were applied to manufacture HAP/Ti composite coatings. The aim was to produce thick and dense deposits and investigate the mechanical, electrochemical and incubation behavior of such biocomposites as potential load bearing materials for biomedical applications.

Biomaterials

Biomaterials
Author : Rosario Pignatello,Teresa Musumeci
Publisher : BoD – Books on Demand
Release Date : 2018-05-02
Category : Technology & Engineering
Total pages :114
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This contribution book collects five among reviews and original articles from eminent experts working in the interdisciplinary area of biomaterial synthesis and application. From their direct and recent experience, the readers can access the novel and ongoing potentialities of different synthetic and engineered biomaterials. Contributions reflect the fundamental studies, with a particular attention to the physico-chemical mechanical characterization of biomaterials, along with biocompatibility studies and potential clinical use. After an introductory chapter on the question of storage stability for biomaterial-based devices and products and for polymeric nanomedicines, a first review deals with the use and commercial sources of hydroxyapatite in tissue engineering and other biomedical applications. A study follows on optical fiber laser marking on the properties of stainless steel in implant manufacturing. Two other reviews, respectively, focused on the approaches to prevent or treat the effects of calcification that occurs in vivo on biomaterial-based implants and on the encapsulation of pancreatic islet cells for the treatment of type I diabetes will be presented. Finally, an overview on the physical bases and application in biomaterial science of the spray-drying process will close the volume. This setting will allow to achieve a general view of how classical and novel biomaterials can be applied, along with the methodologies necessary to design, develop, and characterize them, without the restrictions necessarily imposed by industrial or profit concerns. Readers will be apprised about the methodologies used to develop biomaterials possessing the physical and biological properties needed for specific medical and clinical applications.

Hydroxyapatite Coatings for Biomedical Applications

Hydroxyapatite Coatings for Biomedical Applications
Author : Sam Zhang
Publisher : CRC Press
Release Date : 2013-05-14
Category : Medical
Total pages :469
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Hydroxyapatite coatings are of great importance in the biological and biomedical coatings fields, especially in the current era of nanotechnology and bioapplications. With a bonelike structure that promotes osseointegration, hydroxyapatite coating can be applied to otherwise bioinactive implants to make their surface bioactive, thus achieving faster healing and recovery. In addition to applications in orthopedic and dental implants, this coating can also be used in drug delivery. Hydroxyapatite Coatings for Biomedical Applications explores developments in the processing and property characterization and applications of hydroxyapatite to provide timely information for active researchers and newcomers alike. In eight carefully reviewed chapters, hydroxyapatite experts from the United States, Japan, Singapore, and China present the latest on topics ranging from deposition processes to biomedical applications in implants and drug delivery. This book discusses: Magnetron sputtering and electrochemical deposition The modification of hydroxyapatite properties by sol–gel deposition to incorporate other elements found in natural bones, such as zinc, magnesium, and fluorine The use of pure hydroxyapatite in drug delivery applications The growth or self-assembly of hydroxyapatite on shape memory alloy Hydroxyapatite composite coatings—with carbon nanotubes, titanium dioxide (TiO2), and others—on the titanium alloy Offering valuable insights and a wealth of data, including numerous tables and figures, this is a rich source of information for research on hydroxyapatite coatings. Each chapter also covers material that provides an accessible stepping stone for those who are new to the field.

Microplasma Sprayed Hydroxyapatite Coatings

Microplasma Sprayed Hydroxyapatite Coatings
Author : Arjun Dey,Anoop Kumar Mukhopadhyay
Publisher : CRC Press
Release Date : 2015-03-19
Category : Technology & Engineering
Total pages :272
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There has been enormous growth in the use of medical implants. However, in the case of hip replacement, loosening of metallic prosthesis fixed with polymethylmethylacrylate bone cement has resulted in painstaking revision surgery, which is a major problem for the patient, surgeon, and biomedical technology itself. In fact, global recognition of thi

Surface Modification of Magnesium and its Alloys for Biomedical Applications

Surface Modification of Magnesium and its Alloys for Biomedical Applications
Author : T.S.N. Sankara Narayanan,Il-Song Park,Min-Ho Lee
Publisher : Elsevier
Release Date : 2015-01-30
Category : Technology & Engineering
Total pages :460
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The development of biodegradable implants which can remain in the human body to fix a problem and subsequently dissolve, or be absorbed, consumed or excreted, without warranting a secondary surgery, is very appealing to scientists. Due to their excellent biocompatibility and biodegradability, magnesium implants provide a viable option many problems associated with permanent metallic implants such as, restenosis, thrombosis, permanent physical irritation, and inability to adapt to growth and changes in human body. Volume 2 of this important new book explores practical issues of magnesium and magnesium alloys, physical and mechanical modification and coatings to enhance this material for biomedical applications. Includes expert analysis on chemical solution deposition of hydroxyapatite (HAp) and octacalcium (OCP) phosphate coatings for magnesium Comprehensive coverage of biomimetic modifications, surface functionalization of biomolecules, natural, conducting and biodegradable polymeric coatings Lucid dissection of chemical, physical, mechanical and electromechanical modifications of magnesium and its alloys for biomedical applications

Octacalcium Phosphate Biomaterials

Octacalcium Phosphate Biomaterials
Author : Gerard Insley,Osamu Suzuki
Publisher : Woodhead Publishing
Release Date : 2019-11-20
Category : Medical
Total pages :374
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Octacalcium Phosphate Biomaterials: Past, Present and Future is a comprehensive study of octacalcium phosphate (OCP), a next generation biomaterial for bone regeneration. By focusing both on fundamental research and the use of OCP as a scaffold material, this book explores its potential to deliver improved clinical results. Early chapters in the book discuss OCP's effects on bone cell activity, cellular interactions and their role in bone formation, repair and replacement. Later chapters cover topics such as drug delivery, synthesis methodologies and future analysis techniques. This will be an invaluable and unique resource for researchers, clinicians, students and industrialists in the area of orthopedics and dentistry. OCP is known to be a pre-cursor to hydroxyapatite in the human biomineralization process that forms bone and tooth enamel. Research studies that have emerged in recent years suggest OCP's tremendous potential as a bioactive material. Contains comprehensive, up-to-date information on the basic science, including physical, chemical and biological properties Presents the clinical potential of octacalcium phosphate biomaterials Provides a reference point for new research and increased activity in the area of next generation smarter biomaterials for hard tissue repair and regeneration

316L Stainless Steel/Hydroxyapatite Composite Materials for Biomedical Applications

316L Stainless Steel/Hydroxyapatite Composite Materials for Biomedical Applications
Author : Aurora Anca Poinescu
Publisher : Unknown
Release Date : 2018
Category : Science
Total pages :129
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Hydroxyapatite (HAp) is known as one of the most important biomaterials used for orthopedic and dental applications due to chemical composition similar to that of bone and bioactive properties. However, due to its reduced resistance, HAp should be mixed with different components in order to create composite materials. A good example is austenitic stainless steel (AA 316L), as a class of metallic materials used for biomedical applications. The aim of this chapter is to show a series of our group studies for obtaining a hybrid metal-ceramic composite by powder metallurgy, the physicochemical, mechanical, and biological properties of these hybrid composites and the investigation of possible functional coating layers and adherent bioactive hydroxyapatite Ca10(PO4)6(OH)2 on the metal of 316L stainless steel, correlating our data with literature data. Hardness properties of the obtained composites are close to those of human bones. In biological systems, could be observed that after 6 months, the relevant metals (Fe, Mn, Cr, and Ni) concentration (ppb), that may be released from composite materials in simulated physiological fluids (SBF), is practically zero.

Hydroxyapatite

Hydroxyapatite
Author : Valeri S. Gshalaev,Aleksandra C. Demirchan
Publisher : Nova Biomedical
Release Date : 2012
Category : Science
Total pages :477
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Hydroxyapatite is the most widely accepted biomaterial for the repair and reconstruction of bone tissue defects. It has all the characteristic features of biomaterials, such as, biocompatible, bioactive, osteoconductive, non-toxic, non- inflammatory and non-immunogenic properties. In this book, the authors present current research in the study of the synthesis, properties and applications of hydroxyapatites. Topics discussed include nanodimensional and nanocrystalline hydroxyapatite and other calcium orthophosphates; application of biomimetic nanocrystalline apatites in drug delivery and tissue engineering; polymer matrix mediated synthesis of nano hydroxyapatite crystals; osteointegration of titanium porous implants with carbon nanocoating and hydroxyapatite particles into the pores; hydroxyapatite thin film prepared by sputtering technique for medical applications; and hydroxyapatite application in dentistry and maxillofacial surgery.

Polymer Nanocomposites in Biomedical Engineering

Polymer Nanocomposites in Biomedical Engineering
Author : Kishor Kumar Sadasivuni,Deepalekshmi Ponnamma,Mariappan Rajan,Basheer Ahmed,Al-Maadeed Mariam Ali S A
Publisher : Springer
Release Date : 2019-03-18
Category : Technology & Engineering
Total pages :409
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This book presents a thorough discussion of the physics, biology, chemistry and medicinal science behind a new and important area of materials science and engineering: polymer nanocomposites. The tremendous opportunities of polymer nanocomposites in the biomedical field arise from their multitude of applications and their ability to satisfy the vastly different functional requirements for each of these applications. In the biomedical field, a polymer nanocomposite system must meet certain design and functional criteria, including biocompatibility, biodegradability, mechanical properties, and, in some cases, aesthetic demands. The content of this book builds on what has been learnt in elementary courses about synthesising polymers, different nanoparticles, polymer composites, biomedical requirements, uses of polymer nanocomposites in medicine as well as medical devices and the major mechanisms involved during each application. The impact of hybrid nanofillers and synergistic composite mixtures which are used extensively or show promising outcomes in the biomedical field are also discussed. These novel materials vary from inorganic/ceramic-reinforced nanocomposites for mechanical property improvement to peptide-based nanomaterials, with the chemistry designed to render the entire material biocompatible.

Clinical Applications of Biomaterials

Clinical Applications of Biomaterials
Author : Gurbinder Kaur
Publisher : Springer
Release Date : 2017-06-07
Category : Technology & Engineering
Total pages :467
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This book examines the most novel and state-of-the-art applications of biomaterials, with chapters that exemplify approaches with targeted drug delivery, diabetes, neurodegenerative diseases and cranioplasty implants. Expert contributors analyze biomaterials such as calcium phosphate, sol-gel and quenched glasses, metallic and polymer implants, bioactive glass, and polymer composites while also covering important areas such as the soft tissue replacement, apatites, bone regeneration and cell encapsulation. This book is appropriate for biomedical engineers, materials scientists, and clinicians who are seeking to implement the most advanced approaches and technologies with their patients.

Materials for Biomedical Engineering: Nanobiomaterials in Tissue Engineering

Materials for Biomedical Engineering: Nanobiomaterials in Tissue Engineering
Author : Alina-Maria Holban,Alexandru Grumezescu
Publisher : Elsevier
Release Date : 2019-03-22
Category : Medical
Total pages :512
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Materials for Biomedical Engineering: Nanobiomaterials in Tissue Engineering highlights the impact of novel bioactive materials in both current applications and their potential in the future progress of tissue engineering and regenerative medicine. Tissue engineering is a well investigated and challenging bio-medical field, with promising perspectives to improve and support the quality of life in diseased patients. This book brings together the latest research findings regarding the design and versatility of bioactive materials and their potential in tissue engineering. In addition, recent progress in soft and hard tissue engineering is presented within the chapters of the book. Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of bioactive materials in tissue engineering that can be used by researchers, engineers and academics Includes novel opportunities and ideas for developing or improving technologies in composites by companies, biomedical industries, and in related sectors Features at least 50% of references from the last 2-3 years

Nanobioceramics For Healthcare Applications

Nanobioceramics For Healthcare Applications
Author : Thian Eng San,Huang Jie,Aizawa Mamoru
Publisher : World Scientific
Release Date : 2016-12-27
Category : Technology & Engineering
Total pages :316
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This book provides a comprehensive coverage on nanobioceramics and their potential applications in healthcare. Ground-breaking new discoveries in bioceramics and their properties have meant an increasing interest in the development of how this can be related to nanobiomaterials, and in treating various conditions from osteoporosis to surgical dentistry. Research has also been driven by ageing global populations, where better restorative and reparative treatments are needed. As a consequence of this change in demographics, the research of nanobioceramics for application in healthcare is a field that is advancing at a considerable pace. Individual chapters give the reader an in-depth coverage on the synthesis and characterization of various nanobioceramics including silica, calcium phosphates, bioglass, and glass-ceramics. Through reviewing and analysing current literature, this book provides a rich source of valuable information on nanobioceramics for any professionals and students in materials science and engineering. It is also aimed at medical professionals searching for state-of-the-art techniques and treatments available and made possible through this particular field of innovation.