November 24, 2020

Download Ebook Free Liver Regeneration

Liver Regeneration

Liver Regeneration
Author : Dieter Häussinger
Publisher : Walter de Gruyter
Release Date : 2011
Category : Science
Total pages :210
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Understanding the mechanisms involved in liver regeneration is of crucial importance for clinical medicine, not only regarding carcinogenesis and diabetes treatment, but also for the use of stem cells for cell therapy and liver surgery. This graduate-level text provides an overview of the current state of knowledge of the molecular mechanisms of liver regeneration. Hepatic stem cells are introduced and the important players involved in regeneration such as oval cells, bone marrow and stellate cells are reviewed. The cell signaling pathways that initiate liver regeneration and regulate the switch between proliferation and apoptosis are presented and the role of liver stem cells in tumorigenesis is discussed. The book also treats the epigenetic regulation of liver stem cells and the roles of inflammation and angiogenesis in liver regeneration. This compact overview of the fascinating regenerative capacity of the liver will be of interest to graduate students and post-docs in molecular biology, biochemistry and medicine.

Liver Regeneration

Liver Regeneration
Author : D. Bernuau
Publisher : John Libbey Eurotext
Release Date : 1992
Category : Liver
Total pages :162
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This book represents an exciting approach to the hepatic physiology and multiple developments about cellular biology such as: cell cycle regulation, growth factors and oncogenes.

Liver Regeneration

Liver Regeneration
Author : Pedro Baptista
Publisher : BoD – Books on Demand
Release Date : 2012-05-16
Category : Technology & Engineering
Total pages :264
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Doctors and scientists have been aware of the "phenomenom" of liver regeneration since the time of the ancient Greeks, illustrated by the mythic tale of Prometheus' punishment. Nevertheless, true insight into its intricate mechanisms have only become available in the 20th century. Since then, the pathways and mechanisms involved in restoring the liver to its normal function after injury have been resolutely described and characterized, from the hepatic stem/progenitor cell activation and expansion to the more systemic mechanisms involving other tissues and organs like bone-marrow progenitor cell mobilization. This book describes some of the complex mechanisms involved in liver regeneration and provides examples of the most up-to-date strategies used to induce liver regeneration, both in the clinic and in the laboratory. The information presented will hopefully benefit not only professionals in the liver field, but also people in other areas of science (pharmacology, toxicology, etc) that wish to expand their knowledge of the fundamental biology that orchestrates liver injury and regeneration.

Liver Regeneration

Liver Regeneration
Author : Udayan M. Apte
Publisher : Academic Press
Release Date : 2015-08-13
Category : Medical
Total pages :326
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Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease. By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management. Hundreds of full-color, graphic photographs and illustrations underline key elements and show researchers and students important aspects of liver transplantation, immunofluorescence, and other techniques used in liver regeneration. Summarizes current liver regeneration studies and discussions on expected discoveries Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration Presents details on the molecular mechanisms that affect liver regeneration Highly illustrated, with hundreds of full-color, graphic photographs and illustrations to enhance the learning process

Liver Regeneration in Man

Liver Regeneration in Man
Author : Carroll Moton Leevy
Publisher : Charles C. Thomas Publisher
Release Date : 1973
Category : Liver
Total pages :112
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Liver Regeneration and Carcinogenesis

Liver Regeneration and Carcinogenesis
Author : Gerard Meurant
Publisher : Elsevier
Release Date : 1995-09-27
Category : Science
Total pages :402
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Because of its marked capacity to regenerate and the ability of chemical carcinogens and viruses to ready transform hepatocytes, the liver has been used extensively as a model for investigating the molecular mechanisms of cellular proliferation and carcinogenesis. Recently, striking advances have occured in the understanding of hepatocyte growth regulation and the manner in which chemical agents and viruses alter these normal growth regulatory pathways in liver carcinogenesis. This explosion of information has occured in a multitude of researh disciplines. This book brings together current findings in a coherent manner, from a molecular point of view. Three sections cover in detail the areas of liver regeneration, liver carcinogenesis, and liver tumor therapy. The contributors are pioneers and leaders in this field. * Logical organization of material in three detailed and comprehensive sections: liver regeneration, liver carcinogenesis, and liver tumor treatment * Contributors are pioneers and leaders in the field * There are currently no books on this subject on the market * Research focus is at the molecular level

Stem Cell and Liver Regeneration

Stem Cell and Liver Regeneration
Author : K. Okita
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :87
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Cellular therapy with liver stem cells and their progeny, including bone marrow cells, is a promising new approach that will contribute significantly to the treatment of liver diseases. The existence of the liver stem cell had long been debated, but it is now generally accepted that the liver contains cells with stem-like properties and that these cells can be activated to proliferate and differentiate into mature hepatocytes under certain conditions. There is also a substantial body of evidence to suggest that oval cells are involved in liver regeneration as they differentiate into hepatocytes and biliary cells. This book is a collection of work on stem cell and liver regeneration, initially delivered at the 14th Yamaguchi (Japan) Symposium on Liver Disease. Its nine chapters present the most recent data about basic and clinical research in hepatology in Japan and other countries, providing a valuable resource for researchers and practitioners alike.

Liver Regeneration

Liver Regeneration
Author : Udayan M. Apte
Publisher : Academic Press
Release Date : 2015-08-13
Category : Medical
Total pages :326
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Liver Regeneration: Basic Mechanisms, Relevant Models and Clinical Applications presents cutting-edge information on liver regeneration research through an integrated, systems-wide perspective. The book addresses discoveries on hepatic progenitor cells, liver regeneration after chemical damage, and liver regeneration as a prime therapy for liver failure and disease. By addressing the urgent need for translating basic research findings into clinically relevant modalities and potential therapeutic applications, the book provides the data needed to improve liver patient management. Hundreds of full-color, graphic photographs and illustrations underline key elements and show researchers and students important aspects of liver transplantation, immunofluorescence, and other techniques used in liver regeneration. Summarizes current liver regeneration studies and discussions on expected discoveries Provides an overview of standard scientific and cutting-edge technologies to study liver regeneration Presents details on the molecular mechanisms that affect liver regeneration Highly illustrated, with hundreds of full-color, graphic photographs and illustrations to enhance the learning process

Effect of a Neural Relay on Liver Regeneration in Mice: Activation of Serotonin Release from the Gastrointestinal Tract

Effect of a Neural Relay on Liver Regeneration in Mice: Activation of Serotonin Release from the Gastrointestinal Tract
Author : Anonim
Publisher : Unknown
Release Date : 2018
Category :
Total pages :129
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Abstract : The development of therapeutic options to promote hepatic regeneration following severe liver injury is essential. While humoral factors have been reported as mechanisms of liver regeneration, the contributions of interorgan communication to liver regeneration have not been reported. In this study, we examined the effect of a neural relay on liver regeneration via activation of serotonin release from the gastrointestinal (GI) tract. Our results demonstrated that the afferent visceral nerve from the liver activates the efferent vagus nerve from the brain, leading to activation of serotonin release from the GI tract and contributing to liver regeneration. While it is difficult to apply these results directly to human health, we believe that this study may represent a step toward developing essential therapeutics to promote liver regeneration. Abstract : This study demonstrated that a neural relay, activated by liver damage, contributed to hepatic regeneration. The afferent visceral nerve from the damaged liver stimulated the efferent vagus nerve from the brain, leading to activation of serotonin release from the gastrointestinal tract, which contributed to liver regeneration. These results may represent a step toward developing essential therapeutics to promote liver regeneration.

Liver Growth and Repair

Liver Growth and Repair
Author : A. Strain,Anna Mae Diehl
Publisher : Springer Science & Business Media
Release Date : 1997-12-31
Category : Medical
Total pages :662
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Nelson Fausto The Greek myth of Prometheus with its picture of a vulture feasting on its chained victimhas traditionallyprovided a visualimageofliverregeneration. Itis apowerful and frightening representationbut ifone were to substitute the vulture by a surgeon and Prometheus by a patient laying on a properly prepared operating table, the outcomeoftheprocedurewould not differ significantlyfrom that describedbyGreek poets. Yet few of us who work in the field have stopped long enough to ask where this myth originated. Did the poet observe a case of liver regeneration in a human being? Was it brilliant intuition or perhaps, literally, just a 'gut feeling' of a poet looking for good rhymes that led to the prediction that livers grow when part of the tissueisremoved? Thisbookdoesnotattemptto solve these historical issues. Itdoes, instead, cover in detail some of the major modem themes of research on liver regen eration, injury and repair. As indicated in Dr. N. Bucher's chapter, the modem phase ofexperimental studies on liver regeneration started in 1931 with the publication by Higgins and Anderson of a method to perform a two-thirds resection of the liver of a rat. The technique described has 3 remarkable features: 1) it is highly reproducible, resulting in the removal of 68% of the liver, 2) it has minimal if any mortality, and 3) it consists only of blood vessel ligation and does not involve cutting through or wounding hepatic tissue.

RNA Synthesis During Liver Regeneration and Modulation of RNA Precursos Metabolism During Hepatoma Growth

RNA Synthesis During Liver Regeneration and Modulation of RNA Precursos Metabolism During Hepatoma Growth
Author : Inga Ljungquist
Publisher : Unknown
Release Date : 1983
Category :
Total pages :121
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Regenerative Medicine I

Regenerative Medicine I
Author : Ioannis V. Yannas
Publisher : Springer Science & Business Media
Release Date : 2005-02-10
Category : Medical
Total pages :196
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With contributions by numerous experts

Blumgart's Surgery of the Liver, Pancreas and Biliary Tract E-Book

Blumgart's Surgery of the Liver, Pancreas and Biliary Tract E-Book
Author : William R. Jarnagin
Publisher : Elsevier Health Sciences
Release Date : 2012-03-09
Category : Medical
Total pages :1976
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Comprehensive and complete, Blumgart’s Surgery of the Liver, Pancreas and Biliary Tract – edited by Dr. William R. Jarnagin and a team of experts- delivers the comprehensive, cutting-edge guidance you need to achieve optimal outcomes in surgery of the liver, biliary tract, and pancreas. Edited by a panel of experts and featuring contributions by many leading authorities, this 2-volume reference brings you the latest information on pathology, diagnostics, surgery, and non-operative intervention all in one source. At www.expertconsult.com you can not only access the complete contents online, but also an abundance of detailed illustrations and step-by-step procedural video clips from the Memorial Sloan Kettering video library that show you how to perform key procedures step by step. Glean all essential, up-to-date, need-to-know information in one comprehensive reference that provides extensive coverage of pathology, diagnostics, surgery, and non-operative intervention as well as hepatobiliary and pancreatic surgery. Deepen your understanding of surgical anatomy to help with diagnosis, surgical operation, interventional radiology, and endoscopy. See how to perform key procedures by watching operative videos from the Memorial Sloan Kettering video library. Apply the most advanced diagnostic and management options for each disease, including interventional techniques. Stay current with the latest knowledge and advancements including minimally invasive techniques in hepatic resection; surgical considerations for congenital disorders of the pancreas; non-surgical therapies for pancreatic cancer; microwave ablation and other emerging technologies; the most recent developments in the rapidly changing area of transplantation; and the newest best practices in pre- and post-operative care and blood transfusion. Get in-depth coverage of the pancreas from the only fully comprehensive text on both hepatobiliary and pancreatic surgery. Learn from the very best. Rely on the trusted guidance of experts, with a fresh perspective from senior editor, Dr. William Jarnigan, who has earned a national and international reputation in the surgical management of diseases of the biliary tract. Access the full text online at www.expertconsult.com, along with image and video libraries, tables, figures, and more! Over 200 additional contributing experts. A single, comprehensive reference that covers pathology, diagnostics, surgery, and non-operative intervention all in one text!

Current Topics in Complement

Current Topics in Complement
Author : John D. Lambris
Publisher : Springer Science & Business Media
Release Date : 2007-01-26
Category : Medical
Total pages :406
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The Third Aegean Conferences Workshop on Complement-Associated Diseases, Animal Models, and Therapeutics convened to discuss progress in complement research as it pertains to human disease pathogenesis and therapeutics. The rapid pace of research and new experimental approaches allow an integrated view of the in vivo biology of the complement system. This book collects writings on the functions of complement, pathophysiology, protein structures, design of complement inhibitors, and complement assays discussed at the conference.

MacSween's Pathology of the Liver E-Book

MacSween's Pathology of the Liver E-Book
Author : Alastair D. Burt,Linda D. Ferrell,Stefan G Hubscher,Bernard C. Portmann
Publisher : Elsevier Health Sciences
Release Date : 2011-08-30
Category : Medical
Total pages :820
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MacSween’s Pathology of the Liver delivers the expert know-how you need to diagnose all forms of liver pathology using the latest methods. Updated with all the most current knowledge and techniques, this medical reference book will help you more effectively evaluate and interpret both the difficult and routine cases you see in practice. Compare the specimens you encounter in practice to thousands of high-quality images that capture the appearance of every type of liver disease. Efficiently review all the key diagnostic criteria and differential diagnoses for each lesion.