November 27, 2020

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Mammalian Transcription Analysis and Methods

Mammalian Transcription Analysis and Methods
Author : Ananda L. Roy
Publisher : Elsevier Science
Release Date : 2020-04-01
Category : Science
Total pages :291
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This volume emphasizes analysis and methods for transcription studies. Analysis is covered at both the tissue and molecular level, with a special section on tissue specific transription factors. Over 15 methods are covered, including immunohistochemistry, fluorescence, genomic analysis methodlogy, chromatin remodeling, as well as genetic array/chip analysis.

Transcriptional Regulation in Eukaryotes

Transcriptional Regulation in Eukaryotes
Author : Michael Carey,Michael F. Carey,Stephen T. Smale
Publisher : CSHL Press
Release Date : 2000
Category : Science
Total pages :640
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In the genome era, the analysis of gene expression has become a critical requirement in many laboratories. But there has been no comprehensive source of strategic, conceptual, and technical information to guide this often complex task. Transcriptional Regulation in Eukaryotes answers that need. Written by two experienced investigators, Michael Carey and Stephen Smale at the UCLA School of Medicine, and based in part on the Gene Expression course taught at Cold Spring Harbor Laboratory, this book directly addresses all the concerns of a laboratory studying the regulation of a newly isolated gene and the biochemistry of a new transcription factor. This important and unique book is essential reading for anyone pursuing the analysis of gene expression in model systems or disease states.

Cap-Analysis Gene Expression (CAGE)

Cap-Analysis Gene Expression (CAGE)
Author : Piero Carninci
Publisher : CRC Press
Release Date : 2019-05-08
Category : Science
Total pages :266
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This book is a guide for users of new technologies, as it includes accurately proven protocols, allowing readers to prepare their samples for experiments. Additionally, it is a guide for the bioinformatics tools that are available for the analysis of the obtained tags, including the design of the software, the sources and the Web. Finally, the book provides examples of the application of these technologies to identify promoters, annotate genomes, identify new RNAs and reconstruct models of transcriptional control. Although examples mainly concern mammalians, the discussion expands to other groups of eukaryotes, where these approaches are complementing genome sequencing.

A Handbook of Transcription Factors

A Handbook of Transcription Factors
Author : Timothy R. Hughes
Publisher : Springer Science & Business Media
Release Date : 2011-05-10
Category : Medical
Total pages :306
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Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Issues in General Science and Scientific Theory and Method: 2011 Edition

Issues in General Science and Scientific Theory and Method: 2011 Edition
Author : Anonim
Publisher : ScholarlyEditions
Release Date : 2012-01-09
Category : Science
Total pages :3278
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Issues in General Science and Scientific Theory and Method: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about General Science and Scientific Theory and Method. The editors have built Issues in General Science and Scientific Theory and Method: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about General Science and Scientific Theory and Method in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in General Science and Scientific Theory and Method: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Analysis of Microarray Data

Analysis of Microarray Data
Author : Matthias Dehmer,Frank Emmert-Streib
Publisher : John Wiley & Sons
Release Date : 2008-09-08
Category : Medical
Total pages :438
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This book is the first to focus on the application of mathematical networks for analyzing microarray data. This method goes well beyond the standard clustering methods traditionally used. From the contents: * Understanding and Preprocessing Microarray Data * Clustering of Microarray Data * Reconstruction of the Yeast Cell Cycle by Partial Correlations of Higher Order * Bilayer Verification Algorithm * Probabilistic Boolean Networks as Models for Gene Regulation * Estimating Transcriptional Regulatory Networks by a Bayesian Network * Analysis of Therapeutic Compound Effects * Statistical Methods for Inference of Genetic Networks and Regulatory Modules * Identification of Genetic Networks by Structural Equations * Predicting Functional Modules Using Microarray and Protein Interaction Data * Integrating Results from Literature Mining and Microarray Experiments to Infer Gene Networks The book is for both, scientists using the technique as well as those developing new analysis techniques.

Pathway Analysis for Drug Discovery

Pathway Analysis for Drug Discovery
Author : Anton Yuryev
Publisher : John Wiley & Sons
Release Date : 2008-09-17
Category : Science
Total pages :304
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This book introduces drug researchers to the novel computational approaches of pathway analysis and explains the existing applications that can save time and money in the drug discovery process. It covers traditional computational methods and software for pathway analysis microarray, proteomics, and metabolomics. It explains pathway reconstruction of diseases and toxic states, pathway analysis in various phases, dynamic modeling of drug responses, and more. This is a core resource for drug discovery and pharmaceutical industry researchers, chemists, and biologists and for professionals in related fields.

Handbook of Molecular and Cellular Methods in Biology and Medicine

Handbook of Molecular and Cellular Methods in Biology and Medicine
Author : Leland J. Cseke,Peter B. Kaufman,Gopi K. Podila,Chung-Jui Tsai
Publisher : CRC Press
Release Date : 2003-11-24
Category : Medical
Total pages :600
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Since the publication of the best-selling Handbook of Molecular and Cellular Methods in Biology and Medicine, the field of biology has experienced several milestones. Genome sequencing of higher eukaryotes has progressed at an unprecedented speed. Starting with baker's yeast (Saccharomyces cerevisiae), organisms sequenced now include human (Homo sa

Assessment of Mammalian Embryo Quality

Assessment of Mammalian Embryo Quality
Author : A. van Soom,M. Boerjan
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :406
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Thanks to enormous scientific efforts of the last decades, in vitro fertilization (IVF) and in vitro production (IVP) have now been introduced successfully in the practice of human infertility treatment and cattle breeding programs. This comprehensive book allows us to bridge the knowledge from both biomedical and veterinary fields of research. For the first time, studies concerning the human embryo as well as embryos from domestic species are brought together. The central theme of the book is "the assessment of mammalian embryo quality". In 15 chapters, written by well-known scientists, different aspects of the assessment of mammalian embryo quality are summarized. Non-invasive and invasive techniques to evaluate embryo quality are separated in two parts. In addition the book is provided with appendices on practical aspects and, thus, the book should be present in each laboratory for IVF and IVP.

Genomics and Systems Biology of Mammalian Cell Culture

Genomics and Systems Biology of Mammalian Cell Culture
Author : Wei-Shou Hu,An-Ping Zeng
Publisher : Springer Science & Business Media
Release Date : 2012-03-16
Category : Science
Total pages :290
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Transcriptome Analysis, by Frank Stahl, Bernd Hitzmann, Kai Mutz, Daniel Landgrebe, Miriam Lübbecke, Cornelia Kasper, Johanna Walter und Thomas Scheper Transcriptome Data Analysis for Cell Culture Processes, by Marlene Castro-Melchor, Huong Le und Wei-Shou Hu Modeling Metabolic Networks for Mammalian Cell Systems: General Considerations, Modeling Strategies, and Available Tools, by Ziomara P. Gerdtzen Metabolic Flux Analysis in Systems Biology of Mammalian Cells, by Jens Niklas und Elmar Heinzle Advancing Biopharmaceutical Process Development by System-Level Data Analysis and Integration of Omics Data, by Jochen Schaub, Christoph Clemens, Hitto Kaufmann und Torsten W. Schulz Protein Glycosylation and Its Impact on Biotechnology, by Markus Berger, Matthias Kaup und Véronique Blanchard Protein Glycosylation Control in Mammalian Cell Culture: Past Precedents and Contemporary Prospects, by Patrick Hossler Modeling of Intracellular Transport and Compartmentation, by Uwe Jandt und An-Ping Zeng Genetic Aspects of Cell Line Development from a Synthetic Biology Perspective, by L. Botezatu, S. Sievers, L. Gama-Norton, R. Schucht, H. Hauser und D. Wirth.

Gene Regulation in Eukaryotes

Gene Regulation in Eukaryotes
Author : Edgar Wingender
Publisher : Wiley-Blackwell
Release Date : 1993
Category : Science
Total pages :430
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A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.

Gene Transcription

Gene Transcription
Author : K. Docherty
Publisher : Wiley
Release Date : 1996
Category : DNA-protein interactions
Total pages :121
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The major recent advances in our understanding of the regulation of gene transcription have stemmed largely from our ability to quantify and characterize mRNA. This book describes the methods used for the analysis of RNA, for DNA transfection into mammalian cells, and reporter technology for mapping transcription control elements. Other techniques used in cloning and characterizing transcription factors and in detailed analysis of regulatory sequences are provided in the companion volume to this book, Gene Transcription: DNA Binding Proteins. The Essential Techniques Series books are designed to provide you with immediate access to the protocols you require every day. These handy pocket-sized manuals are easy to carry around, and conveniently spiral bound making them ideal for lab bench work. Written by experienced laboratory researchers, each book in the Essential Techniques Series gives up-to-date, tried and tested practical information for the life scientist. For each key technique these books: introduce the most commonly used methods, explain the advantages and disadvantages of the methods, and give advice on which procedure to use, provide easy to follow step-by-step protocols, with experimental notes and tips on where to pause, plus information on safety and suppliers.

A Laboratory Guide to the Mammalian Embryo

A Laboratory Guide to the Mammalian Embryo
Author : David K. Gardner,Michelle Lane,Andrew J. Watson
Publisher : Oxford University Press
Release Date : 2004-01-08
Category : Science
Total pages :432
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This book pulls together the full range of cell culture, biochemical, microscopic, and genetic techniques to study the early mammalian embryo. Until now, there has never been such a comprehensive compendium, though there have been more focused books of protocol, such as Manipulating the Mouse Embryo, from Cold Spring Harbor. This book is intended to appeal to all constituencies, from basic experimental science to clinical and animal science applications.

Gene Mapping, Discovery, and Expression

Gene Mapping, Discovery, and Expression
Author : Minou Bina
Publisher : Springer Science & Business Media
Release Date : 2006
Category : Science
Total pages :334
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A collection of cutting-edge computational tools and experimental techniques to study how genes are regulated, and to reconstruct the regulatory networks through which various cell-types are produced. On the computational side, web-based technologies to localize genes, to access and retrieve data from microarray databases, to conduct comparative genomics, and to discover the potential genomic DNA that may control the expression of protein-coding genes. Detailed experimental techniques described include methods for studying chromatin structure and allele-specific gene expression, methods for high-throughput analysis to characterize the transcription factor binding elements, and methods for isolating and identifying proteins that interact with DNA.

Molecular Biology of the Cell

Molecular Biology of the Cell
Author : Bruce Alberts
Publisher : Unknown
Release Date : 2004
Category :
Total pages :129
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