June 20, 2021

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Gut Microbiota

Gut Microbiota
Author : Alper Evrensel,Barış Önen Ünsalver
Publisher : BoD – Books on Demand
Release Date : 2018-12-12
Category : Science
Total pages :114
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The gut-brain axis has gained considerable attention from different branches of the scientific community in recent years. In this book, scientists from different disciplines present current scientific knowledge on the topic. The interaction between the prokaryote and eukaryote cells stimulates the evolutionary processes, and results in various systemic illnesses such as neuropsychiatric disorders and may help the continuity of health. Nature has provided us with healthy food that builds our pharmacy. This natural pharmacy store may help the body's healing processes through its effects on gut microbiota and the immune system. This book aims to provide the reader with detailed analyses of the current scientific knowledge on the gut-brain axis and its relation with health and disease. We hope that the reader benefits from the presented material.

The Gut-Brain Axis

The Gut-Brain Axis
Author : Niall Hyland,Catherine Stanton
Publisher : Academic Press
Release Date : 2016-05-13
Category : Medical
Total pages :508
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The Gut-Brain Axis: Dietary, Probiotic, and Prebiotic Interventions on the Microbiota examines the potential for microbial manipulation as a therapeutic avenue in central nervous system disorders in which an altered microbiota has been implicated, and explores the mechanisms, sometimes common, by which the microbiota may contribute to such disorders. Focuses on specific areas in which the microbiota has been implicated in gut-brain communication Examines common mechanisms and pathways by which the microbiota may influence brain and behavior Identifies novel therapeutic strategies targeted toward the microbiota in the management of brain activity and behavior

Microbiota Brain Axis

Microbiota Brain Axis
Author : Jane A. Foster,Rochellys Diaz Heijtz
Publisher : Academic Press
Release Date : 2020-12-15
Category : Medical
Total pages :496
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Microbiota Brain Axis: A Neuroscience Primer provides neuroscience researchers with a comprehensive guide on how to conduct effective microbiota-brain research, understand the appropriate methodologies, and collect and analyze microbiota data. The book begins with an introduction to the importance of the microbiota-brain communication in development and how microbiota impact neurodevelopmental disorders, mental health and neurodegeneration. In addition, the book discusses advances in microbiota analysis tools and techniques for neuroscience related research. Reviews the many approaches to manipulating the microbiota in animal studies - including the use of germ-free animals, antibiotics and diet - and covers the strengths and limitations of each Outlines available microbiota research tools, such as 16S sequencing and shot-gun metagenomics Provides a comprehensive guide to analyzing microbiota-related data and the many choices for bioinformatics

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease
Author : Mark Lyte,John F. Cryan
Publisher : Springer
Release Date : 2014-07-05
Category : Science
Total pages :436
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The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Microbiota-Brain Axis

Microbiota-Brain Axis
Author : Jane A. Foster,Rochellys Diaz Heijtz
Publisher : Academic Press
Release Date : 2020-09-01
Category : Medical
Total pages :496
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Microbiota-Brain Axis: A Neuroscience Primer provides neuroscience researchers with a comprehensive guide on how to conduct effective microbiota-brain research, understand the appropriate methodologies, and collect and analyze microbiota data. The book begins with an introduction to the importance of the microbiota-brain communication in development and how microbiota impact neurodevelopmental disorders, mental health and neurodegeneration. In addition, the book discusses advances in microbiota analysis tools and techniques for neuroscience related research. Reviews the many approaches to manipulating the microbiota in animal studies - including the use of germ-free animals, antibiotics and diet - and covers the strengths and limitations of each Outlines available microbiota research tools, such as 16S sequencing and shot-gun metagenomics Provides a comprehensive guide to analyzing microbiota-related data and the many choices for bioinformatics

Emotional Gut: the Relation Between Gut Microbiome and Mental Health

Emotional Gut: the Relation Between Gut Microbiome and Mental Health
Author : Inu00eas Figueiredo
Publisher : Unknown
Release Date : 2017
Category :
Total pages :129
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The central nervous system and the human gastrointestinal tract are connected via the brain-gut axis, which involves bidirectional communication via neural, endocrine and immune pathways. It has recently been discovered that this communication also involves interactions with the intestinal microbiota, which release immune activating and other signaling molecules that may play an important role in regulating the brain and subsequent behaviour. Since then, it has been found that alterations in the gut microbiota-brain-axis may be implicated in stress-related disorders such as depression and anxiety, neurodevelopmental disorders such as autism, and in cognitive functioning. This discoveries have provided the basis for development of new therapeutic approaches, through the modulation of the microbiota- gut-brain axis by means of prebiotic and probiotic administration. Psychobiotics are a new class of probiotics which, when ingested, confer mental health benefits through interactions with the microbiota-gut-brain axis.MATERIALS AND METHODSNon-systematic review of the literature published in Pubmed/Medline database, using the following keywords:

Microbiome-gut-brain axis

Microbiome-gut-brain axis
Author : R.Z. Sayyed,Mahejibin Khan
Publisher : Springer
Release Date : 2021-07-31
Category : Science
Total pages :129
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The book highlights the importance of prebiotics, probiotics and synbiotics in the signalling mechanism between gut microbiota and brain, also referred to as the gut-brain axis. A stable gut microbiota is essential for normal gut physiology and overall health, since it assists in proper signalling along the brain–gut axis. The book describes how the cross talks between gut microbiota and brain, not only regulate gastro-intestinal functions but also ensure proper functioning of cognitive behaviour and immunological functions. The various chapters describe probiotic microorganisms that colonize gastrointestinal tract and provide an array of health benefits to the host. It further elaborates about certain non-digestible oligosaccharides (prebiotics) are easily fermented by specialist microbes in the gut, to produce health-promoting metabolites and inhibit the growth of pathogenic bacteria. This book is useful for students, researchers and scientists in the field of microbiology, food science and nutrition. It is also meant for industry experts involved in developing nutraceuticals.

Gut Microbiota, Its Modifications and the Gut-brain Axis

Gut Microbiota, Its Modifications and the Gut-brain Axis
Author : Anonim
Publisher : Unknown
Release Date : 2021
Category :
Total pages :129
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Role of Nutraceuticals in Modulation of Gut-Brain Axis in Elderly Persons

Role of Nutraceuticals in Modulation of Gut-Brain Axis in Elderly Persons
Author : Ana-Maria Enciu
Publisher : Unknown
Release Date : 2018
Category : Psychology
Total pages :129
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A rather new and somewhat unusual concept connects brain functions to gut microbiota. It is called "gut-brain axis" (or "microbiota-gut-brain axis") and states that probiotics consumption and a healthy gut microbiota positively influence brain functions related to behavior and cognition. Synergistic with a low chronic grade peripheral inflammation, this faulty barrier exposes the aged brain to negative extra-cerebral signals. Given the quasi-constant failure of pharmacological treatments in neurodegenerative diseases, increased interest is directed toward allopathic medicine, including dietary supplements. Interplay between gut microbiota and central nervous system by immune, neural and metabolic pathways is being explored as a possible modulator of cognitive impairment and behavior disorders. In elderly persons, this axis has been reported to be altered, contributing to systemic inflammation and was also indicated as a possible marker for early frailty in younger population. Currently, there are several clinical trials addressing the relationship between gut microbiota and central nervous system psychiatric disorders and at least one directly investigating whether there is a correlation between composition of gut microbiome, permeability of intestinal barrier and systemic inflammation in patients with dementia. This chapter discusses evidence-based data on positive modulation of gut-brain axis to alleviate behavior and cognition alterations in the elderly.

The Possible Role of the Microbiota-gut-brain-axis in Autism Spectrum Disorder

The Possible Role of the Microbiota-gut-brain-axis in Autism Spectrum Disorder
Author : Piranavie Srikantha
Publisher : Unknown
Release Date : 2019
Category :
Total pages :129
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Nod1/Nod2 Receptors Modulate the Microbiota-Gut-Brain Axis

Nod1/Nod2 Receptors Modulate the Microbiota-Gut-Brain Axis
Author : Melinda A. Schneider
Publisher : Unknown
Release Date : 2015
Category :
Total pages :59
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The association between intestinal diseases, mood disorders and cognitive deficits is increasingly recognized. Previous studies from our lab suggest that chronic intestinal diseases, such as infection with an enteric pathogen, in combination with an acute psychological stressor (water avoidance stress [WAS]), can induce anxiety-like behavior and memory defects in mice. In our current study, we hypothesized that nucleotide binding oligomerization domain (Nod) receptors, as important modulators of homeostasis between the host immune system and the gut microbiota, are integral regulators of the microbiota-gut-brain (MGB) axis. Using Nod1/Nod2 double knockout (NodDKO) mice, we performed behavioral testing, qPCR analysis of stool bacterial DNA, and serum corticosterone analysis. Compared to wild type (WT) controls (C57BL/6), NodDKO mice displayed anxiety-like behaviors (light/dark box test, p

15 - FOOD CREATES MOOD: THE GUT-BRAIN-MICROBIOTA AXIS AND DEPRESSION

15 - FOOD CREATES MOOD: THE GUT-BRAIN-MICROBIOTA AXIS AND DEPRESSION
Author : Sara Rodrigues
Publisher : Unknown
Release Date : 2017
Category :
Total pages :129
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OBJECTIVESThis review aims to shed light on the impact of gut microbiome on mood disorders, particularly depression, as well as to precise which factors influencing gut-brain signaling could be manipulated for better mental health management.BACKGROUND AND AIMSA constant bi-directional communication is known to take place between the gut and the brain. This interaction is referred to in the literature as the gut-brain-microbiota axis and may be key in triggering mood disorders. It is our aim to understand how microbiome respond to external factors and how managing gut bacteria might be useful as a potential therapeutic approach, as evidence on this matter remains limited.MATERIALS AND METHODSWe conducted a review on all articles concerning gut-brain-microbiome axis published in the last 5 years on PubMed database. A query comprising u201cpsychobiotics OR ((microbiome OR microbiota) AND depression)u201d was used, with full-text available articles being selected.RESULTSAn increasing number of studies suggest that gut microbiome exerts direct influence on mental health. As digestion of food by commensal bacteria living in the gut leads to neurotransmitters regulation and creation, gut bacteria affect brain function and human behavior. Recent studies show growing interest in the concept of psychobiotics - bacteria which when ingested may be beneficial to mental health. Its effects via enteric nervous system on emotional and cognitive functions seem to be prominent, with evidence suggesting potential antidepressant effects. CONCLUSIONSGut-brain-microbiome axis management and psychobiotics stand as promising therapeutic alternatives to treat mood disorders such as depression.

The Microbiome and the Brain

The Microbiome and the Brain
Author : David Perlmutter
Publisher : CRC Press
Release Date : 2019-12-06
Category : Medical
Total pages :214
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Brain related disorders are among the most challenging health issues of our time. The development of effective therapeutic and preventive strategies for these disorders relies on a comprehensive understanding of the underlying causative mechanisms. And, until recently, these mechanisms have remained somewhat elusive. The newly discovered pivotal role of the intestinal microbiome in brain health, functionality, and resistance to disease is revolutionizing neuroscience. The Microbiome and the Brain, through the contributions of some of the most forward thinking researchers and clinicians in the field, comprehensively reveals the leading edge of our understanding of the fundamental role of gut microbes and their metabolites in a wide array of seemingly diverse brain issues including Alzheimer’s disease, autism, multiple sclerosis, and mood disorders. In addition, mechanisms defining these relationships are explored along with a presentation of the state-of-the-art as it relates to interpretation of relevant laboratory assessments. Finally, novel therapeutic opportunities, derived from this exciting science are presented. Readers will learn: The highly validated relationship between alterations of gut microbes and their metabolites, and risk for Alzheimer’s disease. The important link between autism and intestinal dysbiosis. Appropriate interpretation of available laboratory assessments of the intestinal microbiome. The potential role of fecal microbial transplant in neurological diseases. The influence of diet and other lifestyle choices on the microbiome as it relates to brain health and functionality.

The Microbiome

The Microbiome
Author : Anonim
Publisher : Academic Press
Release Date : 2020-11-01
Category : Science
Total pages :194
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The Microbiome, Volume 176, assembles known facts and provides guidance for their implementation on topics relating to associations between the gut microbiome and personality traits, depression, anxiety, autism, schizophrenia, cognition, dementia and neurodegeneration. Additionally, this volume considers the influence of the maternal microbiome on brain development, with chapters covering Intervention, prevention, and the brain: prebiotics, probiotics, and fecal transplants, The microbiota-gut-brain axis: focus on the fundamental communication pathways, and Microbiome composition and locations. Provides a comprehensive review of the bidirectional interactions between gut microbes and the brain Includes data across the lifespan Focuses on microbiome related therapies with broad appeal within, and beyond, the medical and scientific community

The Mind-Gut Connection

The Mind-Gut Connection
Author : Emeran Mayer
Publisher : HarperCollins
Release Date : 2018-06-05
Category : Health & Fitness
Total pages :336
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Chances are, at some point in your life you’ve noticed the connection between your brain and your gut. If you’ve ever felt queasy as you walked into an uncomfortable situation or based a life decision based on a “gut feeling,” then you know that sometimes our bodies react faster than our minds. Most of us have also experienced the same phenomenon in reverse, where our mental state has affected our digestive system—like the butterflies in our stomach before an important meeting or a first date. But while the dialogue between the mind and the gut has been recognized for centuries, scientists today are just starting to understand how powerful that connection is. In The Mind-Gut Connection, Dr. Emeran Mayer, executive director of the UCLA Oppenheimer Center for the Neurobiology of Stress, offers a cutting-edge view into this developing science, showing us the full impact of how the brain, gut, and microbiome—the community of microorganisms that live inside the digestive tract—communicate. As Dr. Mayer explains, when this communication channel is out of whack, major health problems can crop up, including food sensitivities and allergies, digestive disorders, obesity, depression, anxiety, and fatigue. The Mind-Gut Connection teaches us how, with a few simple changes to our diet and lifestyle, we can enjoy a happier mindset, enhanced immunity, a decreased risk of developing neurological diseases such as Parkinson’s and Alzheimer’s, and even lose weight. With a simple, practical regimen drawn from the latest research, Dr. Mayer shows us that paying attention to the mind-gut balance is the key to unlocking vibrant health.