December 3, 2020

Download Ebook Free Mitochondrial Case Studies

Mitochondrial Case Studies

Mitochondrial Case Studies
Author : Russell Saneto,Sumit Parikh,Bruce H Cohen
Publisher : Academic Press
Release Date : 2015-11-24
Category : Science
Total pages :338
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Mitochondrial Case Studies: Underlying Mechanisms and Diagnosis offers the science behind mitochondrial disease with a case studies approach. Since mitochondrial diseases are diverse and influenced by genetic, environmental, and social-economic factors, this publication will help students, physicians, scientists, health care students, and families recognize and accurately diagnose mitochondrial disease and learn about potential treatments. Reviews case studies as a helpful teaching tool to increase awareness and improve diagnosis Provides information on underlying mechanisms of mitochondrial disease Includes basic mitochondrial dysfunction research through patient case studies to best illustrate the entire disease process

Neuromuscular Case Studies E-Book

Neuromuscular Case Studies E-Book
Author : Tulio E. Bertorini
Publisher : Elsevier Health Sciences
Release Date : 2008-05-14
Category : Medical
Total pages :632
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In this unique book, Dr. Bertorini guides you through more than 100 cases that demonstrate the diagnosis and management of a wide range of common and rare neuromuscular disorders. No other reference boasts such a large array of clinical studies devoted to all areas of this broad topic! Each case study reviews the etiologies, pathogenesis, differential diagnosis, and management of a particular disorder, helping you not only recognize its presentation, but also determine a diagnosis and the best treatment plans for your patients. You’ll also find expert guidance on the basic mechanisms of neuromuscular disorders, clinical examination, and diagnostic tests—including EMG, muscle biopsy, genetic testing, and more. More than 100 detailed case studies explore both common and rare neuromuscular disorders and the treatment protocols for each, equipping you with the knowledge you need to confidently manage any challenge. Each case includes a summary of important points or highlights of the study. Case studies are arranged either by complaint or by diagnosis so that you can successfully manage your patients with or without an initial diagnosis. Comprehensive coverage of EMGs and nerve conduction studies and other diagnostic tests, including muscle and nerve biopsies and genetic testing, helps you accurately diagnose nerve, muscle, and neuromuscular transmission disorders. Detailed discussions of treatment plans and commonly used drugs enhance your management of autoimmune disorders, painful neuropathy, dysautonomia, and other neuromuscular disorders. A reader-friendly format takes you step by step through the diagnosis and treatment of neuromuscular disorders, from the basic anatomy and physiology of the nerve and muscle through to clinical evaluation, diagnostic testing, and therapy. More than 350 high-quality illustrations, including full-color patient photographs, biopsies, and EMG tracings, make complex concepts easier to understand and apply.

Microbial Source Tracking: Methods, Applications, and Case Studies

Microbial Source Tracking: Methods, Applications, and Case Studies
Author : Charles Hagedorn,Anicet R. Blanch,Valerie J. Harwood
Publisher : Springer Science & Business Media
Release Date : 2011-06-08
Category : Science
Total pages :642
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Understanding the origin of fecal pollution is essential in assessing potential health risks as well as for determining the actions necessary to remediate the quality of waters contaminated by fecal matter. As a result, microbial source tracking (MST) has emerged as a field that has evolved and diversified rapidly since the first approaches were described only a decade ago. In response to the emergence of MST, there have been three large multi-laboratory method comparison studies (two in the US and one in Europe), plus numerous workshops, book chapters, and review articles dedicated to synthesizing information on the topic. Furthermore, a federal (USEPA) guide document describing the uses and limitations of MST methods was published in 2005, and a book dedicated to MST as an emerging issue in food safety was published in 2007. These documents provide a collective body of literature on MST that is both conflicting and complementary, often repetitious, and difficult to condense and interpret. In addition, it does not reflect the current diversity of MST approaches with different organisms, newer methodologies such as quantitative PCR, and anthropogenic chemicals, nor does it embrace the scope of MST research being conducted around the world. The three editors of the book, all with extensive MST expertise, have developed chapters and invited authors who reflect the rich diversity and truly international scope of MST. The unifying theme throughout the book is the design of more standardized approaches to MST that include performance criteria (regardless of method or organism), plus recommendations for field study design and MST implementation. The editors intend that this book will serve as a valuable reference for all those who are involved with

Pediatric Epilepsy Case Studies

Pediatric Epilepsy Case Studies
Author : Kevin Chapman,Jong M. Rho
Publisher : CRC Press
Release Date : 2008-09-18
Category : Science
Total pages :296
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The amount of information currently available on pediatric epilepsy, as with all burgeoning fields, can seem overwhelming. Pediatric Epilepsy Case Studies: From Infancy and Childhood through Adolescence reviews the recent flood of new information on the pathophysiology, genetics, and treatment of the various epilepsy syndromes and distills it into an easy-to-use guide. Edited by respected and well-known leaders in the field, the book provides brief, but thorough, descriptions of the different syndromes commonly encountered in clinical practice across the pediatric range. Grasping the complexity and nuances associated with various epileptic syndromes can be daunting. Therefore, the book begins with an introduction to the fundamentals of epilepsy. Subsequent sections include succinct case presentations and clinically relevant discussions of the more common epilepsy syndromes affecting each age group. The chapter authors describe why they chose each particular case, what they learned, and how it changed their practice. The extensive resource section provides an authoritative guide to relevant findings scattered in the literature. Research in the field of epilepsy will continue at a rapid pace, with the ultimate hope of curing many intractable epilepsy syndromes. Organized chronologically, from neonate through adolescence, this book is the culmination of a group effort involving leading physicians and researchers whose contributions constitute a concise and practical reference for health professionals in training.

Case Studies in Immunology

Case Studies in Immunology
Author : Lois N. Magner
Publisher : Garland Science
Release Date : 2016-02-05
Category : Medical
Total pages :384
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Case Studies in Immunology, Seventh Edition is intended for medical students and undergraduate and graduate students in immunology. It presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms o

Case Studies in Immunology

Case Studies in Immunology
Author : Raif Geha,FRED Rosen
Publisher : Garland Science
Release Date : 2010-07-29
Category : Medical
Total pages :328
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This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.

Concepts and Case Studies in Chemical Biology

Concepts and Case Studies in Chemical Biology
Author : Herbert Waldmann,Petra Janning
Publisher : John Wiley & Sons
Release Date : 2014-06-30
Category : Science
Total pages :464
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Retaining the proven didactic concept of the successful "Chemical Biology - Learning through Case Studies", this sequel features 27 new case studies, reflecting the rapid growth in this interdisciplinary topic over the past few years. Edited by two of the world's leading researchers in the field, this textbook introduces students and researchers to the modern approaches in chemical biology, as well as important results, and the techniques and methods applied. Each chapter presents a different biological problem taken from everyday lab work, elucidated by an international team of renowned scientists. With its broad coverage, this is a valuable source of information for students, graduate students, and researchers working on the borderline between chemistry, biology, and biochemistry.

Current Perspectives on Cardiomyopathies

Current Perspectives on Cardiomyopathies
Author : Angelos Tsipis
Publisher : BoD – Books on Demand
Release Date : 2018-09-26
Category : Medical
Total pages :142
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Advances in the understanding of cardiomyopathies and the growth of cardiology have paralleled one another. Over the years, many classification methods have been developed for cardiomyopathies based on aetiology, structural models and the functional approach. The new concepts and events that have occurred in cardiology generally and in cardiomyopathies specifically are sufficient changes to justify this book. Developments in cardiomyopathies have advanced at a rapid rate, largely because of the progress that has been made in instrumental analysis and the integration of clinical cardiology with other fields of basic research. The material in this book encompasses and blends the knowledge recently acquired in genetics, pathology and physiology with the practical matters of diagnosis and treatment.

Fungal Genetics

Fungal Genetics
Author : Cees Bos
Publisher : CRC Press
Release Date : 1996-03-12
Category : Science
Total pages :456
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This is a concise guide to the combined use of classical and molecular methods for the genetic analysis and breeding of fungi. It presents basic concepts and experimental designs, and demonstrates the power of fungal genetics for applied research in biotechnology and phytopathology. Case studies of Saccharomyces cerevisiae, Candida albicans, Aspergillus niger, Neurospora crassa, Podospora anserina, Phytophthora infestans and others are included.

Heart Failure

Heart Failure
Author : José Marín-García
Publisher : Springer Science & Business Media
Release Date : 2010-06-23
Category : Medical
Total pages :470
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Heart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease. An authoritative contribution to the field, this book provides a detailed description of new findings and emerging methodologies, as well as a critical clinical evaluation of the complex HF syndrome and future therapies. Heart Failure: Bench to Bedside includes a primer on gene profiling and bioenergetics of the normal heart and a discussion of the molecular, genetic, biochemical and cellular techniques critical to understanding HF. Further chapters discuss cardiac remodeling, oxidative stress, and alterations in other organs and systems that are often associated with HF. This book thoughtfully evaluates current and forthcoming diagnostic techniques and therapies, pharmaceutical and pharmacogenomic-based individualized medicine, gene and cell-based therapies, and the search for new frontiers. Heart Failure: Bench to Bedside presents a clear view of up-to-date approaches to clinical diagnosis and treatment, as well as offering insightful critiques of original and creative scientific thoughts on post-genomic HF research.

Mitochondrial Medicine

Mitochondrial Medicine
Author : Pankaj Prasun
Publisher : Academic Press
Release Date : 2019-06-15
Category :
Total pages :364
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Mitochondrial Medicine: A Primer for Healthcare Providers and Translational Researchers is an applied, holistic resource addressing the evolving and multidisciplinary area of mitochondrial disease. In twenty-six short, easily accessible chapters, Dr. Prasun Pankaj discusses the fundamentals of mitochondrial medicine in humans, as well as the pathophysiology, diagnosis, and treatment of mitochondrial diseases. Three all-inclusive sections examine the role of mitochondria in common medical conditions such as diabetes and heart failure, and the full range of inherited mitochondrial diseases, covering the genetic and biochemical basis of both mitochondrial DNA deletion syndromes and point mutation syndromes, their clinical presentation, treatment plans, genetic counseling, prenatal testing, and ongoing research of translational relevance. While providing a solid foundation in its topic area, each chapter in Mitochondrial Medicine is written in an accessible format with illustrative case studies, making for a quick reference at the patient's bedside or clinical laboratory. Includes a basic introduction to mitochondria and their misfunctions in human disease Presents current practice and research in mitochondrial medicine, with emphasis on clinical presentation, diagnosis, treatment, genetic counseling, and prenatal testing Features short, accessible chapters with illustrative case studies for quick reference at the patient's bedside or in the clinical laboratory Provides thorough coverage of inherited mitochondrial disorders, as well as the role of mitochondria in common medical conditions

Mitochondrial Medicine

Mitochondrial Medicine
Author : Salvatore DiMauro,Michio Hirano,Eric A. Schon
Publisher : CRC Press
Release Date : 2006-04-19
Category : Medical
Total pages :368
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Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases. A unique work, this text covers a range of specialties, including cardiology, ophthalmology, otology, nephrology, gastroenterology, hematology-oncology, and reproductive medicine, and does not focus exclusively on the more commonly known neurologic conditions. An accessible, user-friendly text, it also presents translational concepts of mitochondrial biogenesis and genetics in vignettes related to specific questions raised by the disease under discussion, rather than concentrating on basic science, which can often intimidate clinicians. This pioneering work is primarily directed to a clinical audience who are interested in the diverse and diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.

Mitochondria and the Heart

Mitochondria and the Heart
Author : José Marín-García
Publisher : Springer Science & Business Media
Release Date : 2005-05-05
Category : Medical
Total pages :400
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Mitochondria have been pivotal in the development of some of the most important ideas in modern biology. Since the discovery that the organelle has its own DNA and specific mutations were found in association with neuromuscular and cardiovascular diseases and with aging, an extraordi-nary number of publications have followed, and the term mitochondrial medicine was coined. Furthermore, our understanding of the multiple roles that mitochondria play in cardiac cell homeostasis opened the door for intensive experimentation to understand the pathogenesis and to find new treatments for cardiovascular diseases. Besides its role in adenosine triphosphate generation, mitochondria regu-late a complex network of cellular interactions, involving (1) generation and detoxification of reactive oxygen species, including superoxide anion, hy-drogen peroxide, and hydroxyl radical; (2) maintenance of the antioxidant glutathione in a reduced state and adequate level of mitochondrial matrix superoxide dismutase; (3) cytoplasmic calcium homeostasis, particularly under conditions of cellular calcium loading; (4) transport of metabolites between cytoplasm and matrix; (5) both programmed (apoptosis) and necrotic cell death; and (6) cell growth and development. It is therefore not surprising that this organelle has come to be the center stage in many current investigations of cardiovascular diseases, aging, and agi- related disease. Concomitant with these advances, an impressive effort is under- way for the development of new tools and methodologies to study mitochondrial structure and function, including powerful ways to visualize, monitor, and alter the organelle function to assess the genetic consequences of these perturbations.

Mitochondrial Medicine

Mitochondrial Medicine
Author : Salvatore DiMauro,Michio Hirano,Eric A. Schon
Publisher : CRC Press
Release Date : 2019-11-29
Category :
Total pages :16
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Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases. A unique work, this text covers a range of specialties, including cardiology, ophthalmology, otology, nephrology, gastroenterology, hematology-oncology, and reproductive medicine, and does not focus exclusively on the more commonly known neurologic conditions. An accessible, user-friendly text, it also presents translational concepts of mitochondrial biogenesis and genetics in vignettes related to specific questions raised by the disease under discussion, rather than concentrating on basic science, which can often intimidate clinicians. This pioneering work is primarily directed to a clinical audience who are interested in the diverse and diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.

Case Studies for Complementary Therapists

Case Studies for Complementary Therapists
Author : Kelly Galvin,Madelaine Bishop
Publisher : Elsevier Health Sciences
Release Date : 2011-08-17
Category : Medical
Total pages :733
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An invaluable resource for complementary therapists, health practitioners, students and teachers Case Studies for Complementary Therapists: a collaborative approach provides curriculum-level support for those working to develop the complementary potential between alternative medicines and conventional western medicine. This useful complementary medicine textbook provides insight into the initial complementary and alternative medicine (CAM) consultation process. It offers possible treatment and collaborative referral options for individual cases, rather than dictating diagnostic analysis or treatment protocols for specific health conditions. Through case studies on conditions like rheumatoid arthritis and fibromyalgia, the book provides an important framework for clinicians and students, within which they can analyse and classify information gathered during consultation. The book will also help readers develop effective and appropriate treatment programs within the time constraints of a busy clinic. Case Studies for Complementary Therapists provides suggestions for questions to ask at consultation time; helping readers collect the necessary information to develop a working diagnosis and treatment protocol. Complementary medicine ethics and law Complementary practitioners are often uncertain about the legal and ethical boundaries in diagnosis and case management. Case Studies for Complementary Therapists: a collaborative approach will help complementary and alternative medicine practitioners and students: • recognise medical situations requiring referral • understand their role in collaborative case management • integrate complementary and alternative medicine modalities in treatment programs with confidence Provides a clear case analysis format which can be and adapted to suit the requirements of individual case histories Specific questioning format Clearly identifies situations where cross or collaborative referral is necessary Decision tables help readers prioritise treatment, refer appropriately and help guide clinical thinking when readers are faced with several treatment options. Class tested, curriculum based