January 27, 2021

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Modeling and Control of Infectious Diseases in the Host

Modeling and Control of Infectious Diseases in the Host
Author : Esteban A. Hernandez-Vargas
Publisher : Academic Press
Release Date : 2019-02-15
Category : Technology & Engineering
Total pages :220
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Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R. Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases Presents a theoretic approach to schedule drug treatments

Modeling and Control of Infectious Diseases in the Host

Modeling and Control of Infectious Diseases in the Host
Author : Esteban A. Hernandez-Vargas
Publisher : Academic Press
Release Date : 2019-02-14
Category : Technology & Engineering
Total pages :256
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Modeling and Control of Infectious Diseases in the Host: With MATLAB and R provides a holistic understanding of health and disease by presenting topics on quantitative decision-making that influence the development of drugs. The book presents modeling advances in different viral infections, dissecting detailed contributions of key players, along with their respective interactions. By combining tailored in vivo experiments and mathematical modeling approaches, the book clarifies the relative contributions of different underlying mechanisms within hosts of the most lethal viral infections, including HIV, influenza and Ebola. Illustrative examples for parameter fitting, modeling and control applications are explained using MATLAB and R. Provides a multi-scale framework to link within-host infection dynamics (individual level) to between-host transmission fitness (epidemiological level) in viral infectious diseases Includes PK/PD modeling and simulation approaches to improve efficiency and decision-making at preclinical development phases Presents a theoretic approach to schedule drug treatments

Modeling Infectious Diseases in Humans and Animals

Modeling Infectious Diseases in Humans and Animals
Author : Matt J. Keeling,Pejman Rohani
Publisher : Princeton University Press
Release Date : 2011-09-19
Category : Science
Total pages :408
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For epidemiologists, evolutionary biologists, and health-care professionals, real-time and predictive modeling of infectious disease is of growing importance. This book provides a timely and comprehensive introduction to the modeling of infectious diseases in humans and animals, focusing on recent developments as well as more traditional approaches. Matt Keeling and Pejman Rohani move from modeling with simple differential equations to more recent, complex models, where spatial structure, seasonal "forcing," or stochasticity influence the dynamics, and where computer simulation needs to be used to generate theory. In each of the eight chapters, they deal with a specific modeling approach or set of techniques designed to capture a particular biological factor. They illustrate the methodology used with examples from recent research literature on human and infectious disease modeling, showing how such techniques can be used in practice. Diseases considered include BSE, foot-and-mouth, HIV, measles, rubella, smallpox, and West Nile virus, among others. Particular attention is given throughout the book to the development of practical models, useful both as predictive tools and as a means to understand fundamental epidemiological processes. To emphasize this approach, the last chapter is dedicated to modeling and understanding the control of diseases through vaccination, quarantine, or culling. Comprehensive, practical introduction to infectious disease modeling Builds from simple to complex predictive models Models and methodology fully supported by examples drawn from research literature Practical models aid students' understanding of fundamental epidemiological processes For many of the models presented, the authors provide accompanying programs written in Java, C, Fortran, and MATLAB In-depth treatment of role of modeling in understanding disease control

Infectious Diseases of Humans

Infectious Diseases of Humans
Author : Roy M. Anderson,Robert M. May
Publisher : Oxford University Press
Release Date : 1992-08-27
Category : Medical
Total pages :757
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Combines mathematical models with extensive use of epidemiological and other data to achieve a better understanding of the overall dynamics of populations of pathogens or parasites and their human hosts, thus providing an analytic framework for evaluating public health strategies.

Modeling to Inform Infectious Disease Control

Modeling to Inform Infectious Disease Control
Author : Niels G. Becker
Publisher : CRC Press
Release Date : 2015-04-28
Category : Mathematics
Total pages :208
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Effectively Assess Intervention Options for Controlling Infectious DiseasesOur experiences with the human immunodeficiency virus (HIV), severe acute respiratory syndrome (SARS), and Ebola virus disease (EVD) remind us of the continuing need to be vigilant against the emergence of new infectious diseases. Mathematical modeling is increasingly used i

Mathematical and Statistical Modeling for Emerging and Re-emerging Infectious Diseases

Mathematical and Statistical Modeling for Emerging and Re-emerging Infectious Diseases
Author : Gerardo Chowell,James M. Hyman
Publisher : Springer
Release Date : 2016-07-27
Category : Mathematics
Total pages :356
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The contributions by epidemic modeling experts describe how mathematical models and statistical forecasting are created to capture the most important aspects of an emerging epidemic.Readers will discover a broad range of approaches to address questions, such as Can we control Ebola via ring vaccination strategies? How quickly should we detect Ebola cases to ensure epidemic control? What is the likelihood that an Ebola epidemic in West Africa leads to secondary outbreaks in other parts of the world? When does it matter to incorporate the role of disease-induced mortality on epidemic models? What is the role of behavior changes on Ebola dynamics? How can we better understand the control of cholera or Ebola using optimal control theory? How should a population be structured in order to mimic the transmission dynamics of diseases such as chlamydia, Ebola, or cholera? How can we objectively determine the end of an epidemic? How can we use metapopulation models to understand the role of movement restrictions and migration patterns on the spread of infectious diseases? How can we capture the impact of household transmission using compartmental epidemic models? How could behavior-dependent vaccination affect the dynamical outcomes of epidemic models? The derivation and analysis of the mathematical models addressing these questions provides a wide-ranging overview of the new approaches being created to better forecast and mitigate emerging epidemics. This book will be of interest to researchers in the field of mathematical epidemiology, as well as public health workers.

Infectious Disease Epidemiology

Infectious Disease Epidemiology
Author : Ibrahim Abubakar,Helen R. Stagg,Ted Cohen,Laura C. Rodrigues
Publisher : Oxford University Press
Release Date : 2016-04-07
Category : Medical
Total pages :416
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Infectious Disease Epidemiology is a concise reference guide which provides trainees and practicing epidemiologists with the information that they need to understand the basic concepts necessary for working in this specialist area. Divided into two sections, part one comprehensively covers the basic principles and methods relevant to the study of infectious disease epidemiology. It is organised in order of increasing complexity, ranging from a general introduction to subjects such as mathematical modelling and sero-epidemiology. Part two examines key major infectious diseases that are of global significance. Grouped by their route of transmission for ease of reference, they include diseases that present a particular burden or a high potential for causing mortality. This practical guide will be essential reading for postgraduate students in infectious disease epidemiology, health protection trainees, and practicing epidemiologists.

Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases

Analyzing and Modeling Spatial and Temporal Dynamics of Infectious Diseases
Author : Dongmei Chen,Bernard Moulin,Jianhong Wu
Publisher : John Wiley & Sons
Release Date : 2014-10-27
Category : Medical
Total pages :496
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Infection Control in Home Care and Hospice

Infection Control in Home Care and Hospice
Author : Emily Rhinehart,Mary M. Friedman
Publisher : Jones & Bartlett Learning
Release Date : 2005-05
Category : Medical
Total pages :245
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An official publication of the Association for Professionals in Infection Control and Epidemiology, Inc. (APIC), the highly successful Infection Control in Home Care and Hospice helps home care providers assess the infection control needs of their organization, and develop home care infection and surveillance programs. The Second Edition has been thoroughly updated and revised with the latest CDC Guidelines on infection control in home care, including Hand Hygiene, Prevention of IV-related Infections, and the 2004 Isolation Guideline.

Urbanization and Slums

Urbanization and Slums
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Release Date : 2018-07-08
Category : Medical
Total pages :148
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The urban built environment is a prime setting for microbial transmission, because just as cities serve as hubs for migration and international travel, components of the urban built environment serve as hubs that drive the transmission of infectious disease pathogens. The risk of infectious diseases for many people living in slums is further compounded by their poverty and their surrounding physical and social environment, which is often overcrowded, is prone to physical hazards, and lacks adequate or secure housing and basic infrastructure, including water, sanitation, or hygiene services. To examine the role of the urban built environment in the emergence and reemergence of infectious diseases that affect human health, the National Academies of Sciences, Engineering, and Medicine planned a public workshop. This publication summarizes the presentations and discussions from the workshop.

Trends in Infectious Diseases

Trends in Infectious Diseases
Author : Shailendra K. Saxena
Publisher : BoD – Books on Demand
Release Date : 2014-04-23
Category : Medical
Total pages :216
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This book gives a comprehensive overview of recent trends in infectious diseases, as well as general concepts of infections, immunopathology, diagnosis, treatment, epidemiology and etiology to current clinical recommendations in management of infectious diseases, highlighting the ongoing issues, recent advances, with future directions in diagnostic approaches and therapeutic strategies. The book focuses on various aspects and properties of infectious diseases whose deep understanding is very important for safeguarding human race from more loss of resources and economies due to pathogens.

Mathematical Modelling and Analysis of Infectious Diseases

Mathematical Modelling and Analysis of Infectious Diseases
Author : Khalid Hattaf,Hemen Dutta
Publisher : Springer Nature
Release Date : 2020-08-31
Category : Technology & Engineering
Total pages :342
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This book discusses significant research and study topics related to mathematical modelling and analysis of infectious diseases. It includes several models and modelling approaches with different aims, such as identifying and analysing causes of occurrence and re-occurrence, causes of spreading, treatments and control strategies. A valuable resource for researchers, students, educators, scientists, professionals and practitioners interested in gaining insights into various aspects of infectious diseases using mathematical modelling and mathematical analysis, the book will also appeal to general readers wanting to understand the dynamics of various diseases and related issues. Key Features Mathematical models that describe population prevalence or incidence of infectious diseases Mathematical tools and techniques to analyse data on the incidence of infectious diseases Early detection and risk estimate models of infectious diseases Mathematical models that describe the transmission of infectious diseases and analyse data Dynamical analysis and control strategies for infectious diseases Studies comparing the utility of particular models in describing infected diseases-related issues such as social, health and economic

Mathematical Tools for Understanding Infectious Disease Dynamics

Mathematical Tools for Understanding Infectious Disease Dynamics
Author : Odo Diekmann,Hans Heesterbeek,Tom Britton
Publisher : Princeton University Press
Release Date : 2012-11-18
Category : Mathematics
Total pages :502
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Mathematical modeling is critical to our understanding of how infectious diseases spread at the individual and population levels. This book gives readers the necessary skills to correctly formulate and analyze mathematical models in infectious disease epidemiology, and is the first treatment of the subject to integrate deterministic and stochastic models and methods. Mathematical Tools for Understanding Infectious Disease Dynamics fully explains how to translate biological assumptions into mathematics to construct useful and consistent models, and how to use the biological interpretation and mathematical reasoning to analyze these models. It shows how to relate models to data through statistical inference, and how to gain important insights into infectious disease dynamics by translating mathematical results back to biology. This comprehensive and accessible book also features numerous detailed exercises throughout; full elaborations to all exercises are provided. Covers the latest research in mathematical modeling of infectious disease epidemiology Integrates deterministic and stochastic approaches Teaches skills in model construction, analysis, inference, and interpretation Features numerous exercises and their detailed elaborations Motivated by real-world applications throughout

Modeling the Transmission and Prevention of Infectious Disease

Modeling the Transmission and Prevention of Infectious Disease
Author : Christon J. Hurst
Publisher : Springer
Release Date : 2017-08-31
Category : Science
Total pages :286
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This volume focuses on blocking disease transmission and the ecological perspective of pathogens and pathogenic processes. The chapters on blocking transmission cover the environmental safety of space flight, biocides and biocide resistance, as well as infection control in healthcare facilities. The book also offers insights into the ecological aspects of infectious disease, introducing the reader to the role of indigenous gut microbiota in maintaining human health and current discussions on environmentally encountered bacterial and fungal pathogens including species that variously cause the necrotizing skin disease Buruli ulcer and coccidioidomycosis. Further, it explores the influenza A virus as an example for understanding zoonosis. It is a valuable resource for microbiologists and biomedical scientists alike.

Social Phenomena

Social Phenomena
Author : Bruno Gonçalves,Nicola Perra
Publisher : Springer
Release Date : 2015-08-14
Category : Science
Total pages :260
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This book focuses on the new possibilities and approaches to social modeling currently being made possible by an unprecedented variety of datasets generated by our interactions with modern technologies. This area has witnessed a veritable explosion of activity over the last few years, yielding many interesting and useful results. Our aim is to provide an overview of the state of the art in this area of research, merging an extremely heterogeneous array of datasets and models. Social Phenomena: From Data Analysis to Models is divided into two parts. Part I deals with modeling social behavior under normal conditions: How we live, travel, collaborate and interact with each other in our daily lives. Part II deals with societal behavior under exceptional conditions: Protests, armed insurgencies, terrorist attacks, and reactions to infectious diseases. This book offers an overview of one of the most fertile emerging fields bringing together practitioners from scientific communities as diverse as social sciences, physics and computer science. We hope to not only provide an unifying framework to understand and characterize social phenomena, but also to help foster the dialogue between researchers working on similar problems from different fields and perspectives.