November 27, 2020

Download Ebook Free Modeling The Psychopathological Dimensions Of Schizophrenia

Modeling the Psychopathological Dimensions of Schizophrenia

Modeling the Psychopathological Dimensions of Schizophrenia
Author : Mikhail Pletnikov,John Waddington
Publisher : Academic Press
Release Date : 2015-11-05
Category : Medical
Total pages :548
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Modeling the Psychopathological Dimensions of Schizophrenia: From Molecules to Behavior is the first book to offer a comprehensive review of the new theoretical, clinical, and basic research framework that considers psychotic illness as a group of dimensional representations of psychopathology rather than as traditional distinct categorical diagnoses. Psychotic illness, typified by schizophrenia, is a devastating condition increasingly recognized as a disorder of abnormal brain development and dysconnectivity. Its complex etiology involves both genetic and environmental factors, as well as the interplay among them. This book describes the current understanding of the clinical and pathological features of schizophrenia, with a particular focus on the evolving conceptualization of schizophrenia and related diagnostic categories of psychotic illness as combinations of dimensional abnormalities. It provides an overview of modern strategies for generating cellular and whole animal models of schizophrenia as well as detailed reviews of the specific experimental preparations and paradigms aimed at molecular, developmental, and brain-network mechanisms that are the underlying aspects of abnormal behavior and various aspects of schizophrenia. This groundbreaking book is an authoritative overview of the translational impact of emerging clinical insights on basic research approaches in schizophrenia that will advance the reader’s understanding of the five major dimensions of psychopathology in schizophrenia and related psychoses and resolve the genetic and neurobiological underpinnings of these dimensions. Includes reviews of animal models that capture the most recent insights into the etiology and pathogenetic mechanisms of schizophrenia, with an emphasis on the translational potential of these models Contains a series of reviews of recently available cellular models for analysis of signaling pathways and gene expression, which complement behavioral neuroscience research in schizophrenia Edited and authored by leading researchers in the field of schizophrenia and related psychoses

Oxford Textbook of Psychopathology

Oxford Textbook of Psychopathology
Author : Paul H. Blaney,Robert F. Krueger,Theodore Millon
Publisher : Oxford University Press, USA
Release Date : 2014-09-19
Category : Psychology
Total pages :851
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While most abnormal psychology texts seem to aim solely for breadth, the acclaimed Oxford Textbook of Psychopathology aims for depth, with a focus on adult disorders and special attention given to the personality disorders. Now in its third edition, it has established itself as an unparalleled guide for professionals and graduate students alike. Esteemed editors Paul H. Blaney, Robert F. Krueger, and the late Theodore Millon selected the most eminent researchers in abnormal psychology to cover all the major mental disorders, allowing them to discuss notable issues in the various pathologies which are their expertise. This third edition of the Oxford Textbook of Psychopathology is fully updated according to the DSM-5 and also reflects alternative, emerging perspectives in the field (e.g., the NIMH's Research Domain Criteria Initiative; RDoC). The Textbook exposes readers to exceptional scholarship, a history of psychopathology, the logic of the best approaches to current disorders, and an expert outlook on what researchers and mental health professionals will be facing in the years to come. With extensive coverage of personality disorders and issues related to classification and differential diagnosis, this volume will be exceptionally useful for all mental health workers, clinical psychologists, psychiatrists, and social workers, and as a textbook focused on understanding psychopathology in depth, as well as a valuable guide for graduate psychology students and psychiatric residents.

Translational Neuropsychopharmacology

Translational Neuropsychopharmacology
Author : Trevor W. Robbins,Barbara J. Sahakian
Publisher : Springer
Release Date : 2016-09-22
Category : Medical
Total pages :498
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This book covers wide areas of animal and human psychopharmacology with clinical utility in the treatment of psychiatric and neurological (e.g Alzheimer's disease) disorders. The main theme is to develop a new paradigm for drug discovery that questions the claim that animal models or assays fail adequately to predict Phase 3 clinical trials. A new paradigm is advocated that stresses the importance of intermediate staging points between these extremes that depend on suitable translation of findings from animal studies to Phase 1 or Phase 2 studies utilising experimental medicine.

Novel Antischizophrenia Treatments

Novel Antischizophrenia Treatments
Author : Mark A. Geyer,Gerhard Gross
Publisher : Springer Science & Business Media
Release Date : 2012-10-01
Category : Medical
Total pages :458
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This volume tries to put current therapy - achievements, shortcomings, remaining medical needs - and emerging new targets into the context of increasing knowledge regarding the genetic and neurodevelopmental contributions to the pathophysiology of schizophrenia. Some of the chapters also deal with respective experimental and clinical methodology, biomarkers, and translational aspects of drug development. The volume concentrates on reviewing the ongoing research attempting to identify novel treatments for the cognitive deficits and negative symptoms of schizophrenia, which are not treated adequately by current antipsychotic medications.

Psychotic Disorders

Psychotic Disorders
Author : Carol A. Tamminga MD,Jim van Os MD, PhD, MRCPsych,Ulrich Reininghaus PhD, MSc, Dipl.-Psych.,Elena Ivleva MD, PhD
Publisher : Oxford University Press
Release Date : 2020-10-20
Category :
Total pages :400
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Psychotic Disorders: Comprehensive Conceptualization and Treatments emphasizes a dimensional approach to psychosis--one of the most fascinating manifestations of altered brain behavior--that cuts across a broad array of psychiatric diagnoses from schizophrenia to affective psychosis and organic disorders like epilepsy and dementias. Written by an international roster of over seventy leading experts in the field, this volume comprehensively reviews, critiques, and integrates available knowledge on the etiology, mechanisms, and treatments of psychotic disorders, and outlines ways forward in both research and clinical practice towards more objective, mechanistically-based definitions of psychotic disorders. Chapters address topics such as psychosis phenomenology, biomarkers and treatments, the overlaps and interfaces between psychiatric disorders within the psychosis dimension, and novel disease definitions. Furthermore, the volume incorporates findings on potential mechanisms, bridges between various system levels (i.e., genetic, epigenetic, molecular and cellular, brain circuit and function, psychological, social, environmental and cultural) and their interactions, as well as the potential role in causation and/or mediation in psychotic disorders. Finally, the volume outlines a broad array of treatment approaches, from the readily available (e.g., psychopharmacology, various modalities of psychotherapy) to the experimental (e.g., cognitive interventions, neuromodulation). With a concluding section of forward perspectives conjecturing future directions and related challenges, this book aspires to stimulate new knowledge, generate novel frameworks, and carry new directions forward on psychotic disorders.

The Epidemiology of Schizophrenia

The Epidemiology of Schizophrenia
Author : Robin M. Murray,Peter B. Jones,Ezra Susser,Jim Van Os,Mary Cannon
Publisher : Cambridge University Press
Release Date : 2002-11-28
Category : Medical
Total pages :129
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An international team of leading researchers and clinicians here provide a comprehensive, epidemiological overview of this multi-faceted and still perplexing disorder, and address some of the key questions it raises. How important in the genetic contribution to schizophrenia? Do pregnancy and birth complications increase the risk for schizophrenia? Is the incidence of schizophrenia changing? Why is the rate higher among immigrants and in those born in cities? Controversial issues such as the validity of discrete or dimensional classifications of schizophrenia and the continuum between psychosis and 'normality' are explored in depth, and separate chapters are devoted to topics of particular relevance to schizophrenia such as suicide, violence and substance abuse. Finally, new prospects for treatment and prevention are considered. Drawing together the findings from social, genetic, developmental and classical epidemiology of schizophrenia, this text will prove an invaluable resource for clinicians and researchers.

Re-Visioning Psychiatry

Re-Visioning Psychiatry
Author : Laurence J. Kirmayer,Robert Lemelson,Constance A. Cummings
Publisher : Cambridge University Press
Release Date : 2015-07-29
Category : Medical
Total pages :563
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Revisioning Psychiatry brings together new perspectives on the causes and treatment of mental health problems. The contributors emphasize the importance of understanding experience and explore how the brain, the person, and the social world interact to give rise to mental health problems as well as resilience and recovery.

Psychopathology and the Family

Psychopathology and the Family
Author : Jennifer Hudson,Ron Rapee
Publisher : Elsevier
Release Date : 2005-10-11
Category : Social Science
Total pages :398
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Understanding the factors that place an individual at greater risk of developing psychopathology has important implications for both treatment and prevention of psychological disorders. Of critical relevance in this regard is the exploration of the potential influence of the family. Parenting and the family environment are considered to significantly contribute to a child's early development and adjustment. It follows then that parental behavior may also be of importance in the development, maintenance and or the prevention of psychopathology. Over the past 50 years there has been a considerable amount of research as well as controversy surrounding the link between parenting and psychopathology. The purpose of this book is to provide researchers and clinicians with state-of-the art research findings, presented by experts in the field, on the role of the family in the development and maintenance of psychopathology. This edited book is divided into 3 sections. The first addresses broader issues of theory and methodology and the second provides separate chapters relating to the role of the family in the development and maintenance of specific psychopathologies. A final section discusses the involvement of the family in treatment and prevention.

Madness Explained

Madness Explained
Author : Richard P Bentall
Publisher : Penguin UK
Release Date : 2003-06-05
Category : Psychology
Total pages :656
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Today most of us accept the consensus that madness is a medical condition: an illness, which can be identified, classified and treated with drugs like any other. In this ground breaking and controversial work Richard Bentall shatters the myths that surround madness. He shows there is no reassuring dividing line between mental health and mental illness. Severe mental disorders can no longer be reduced to brain chemistry, but must be understood psychologically, as part of normal behaviour andhuman nature. Bentall argues that we need a radically new way of thinking about psychosis and its treatment. Could it be that it is a fear of madness, rather than the madness itself, that is our problem?

Modeling Complex Systems

Modeling Complex Systems
Author : John William Shuart,Bill Shuart,William Delbert Spaulding,Jeffrey Stephen Poland
Publisher : U of Nebraska Press
Release Date : 2007
Category : Psychology
Total pages :314
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Capturing the complexity of human behavior has been a recurring theme in the Nebraska Symposium on Motivation. The contributors to this volume describe contemporary approaches to the modeling of complex cognitive and behavioral processes, ranging from molecular to molar phenomena. Although the essays reflect a wide range of theoretical and epistemic perspectives, they all incorporate complex frameworks of dynamic, systemlike relationships involving perception, learning, concept formation, emotion, motivation, intention, behavior, and the social context in which behavior occurs. The editors introduce the volume with a survey of the lifetime of the symposium, showing the development of ideas about behavioral and psychological complexity for over fifty years. A special feature of this collection is its emphasis on practical applications of the conceptual frameworks in which they work. The contributors provide examples of translational research ranging from clinical neuropsychology to self-actualization, from medical informatics to industrial psychology, from programmed learning to psychiatric rehabilitation.

Sims' Symptoms in the Mind

Sims' Symptoms in the Mind
Author : Femi Oyebode
Publisher : Elsevier Health Sciences
Release Date : 2008-04-25
Category : Medical
Total pages :500
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SIMS' SYMPTOMS IN THE MIND has, since its first publication in 1988, become established as the leading introductory textbook on clinical psychopathology. This new edition has been fully updated to include advances in neuropsychology and cognitive neuroscience and changes can be found in the chapters on memory disturbance, disorders of time, pathology of perception, disorders of speech and language, affect and emotional disorders, and disorders of volition and execution. In some cases, novel classifications of the abnormalities under consideration have been provided together with additional pathological phenomena - including palinopsia, akinetopsia, zeitraffer phenomenon, exosomesthesia - many of which have been rediscovered or imported from neurology. The popular and distinctive features are the use of figures, tables and illustrative case examples which have been further enhanced with additional case examples from the classical literature, autobiographical narratives and fiction. New section headings provide firmer thematic unity to the content Check boxes summarize important points such as classification of particular areas Additional examples of psychopathology are included which are drawn from a wide source including fiction, autobiography and clinical textbooks Includes an extended range of abnormalities, including those which have previously been neglected, such as alloaesthesia, palinaptia, teleopsia, pelopsia, akinetopsia, palinopsia, and paraprosopia Fully updated description of the theoretical aspects of memory and its disturbance Fully integrated neuropsychological concepts of imagery and internal mental representations in the chapter on abnormalities of perception

An Experiential Approach to Psychopathology

An Experiential Approach to Psychopathology
Author : Giovanni Stanghellini,Massimiliano Aragona
Publisher : Springer
Release Date : 2016-08-09
Category : Medical
Total pages :383
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This book introduces the reader to a clear and consistent method for in-depth exploration of subjective psychopathological experiences with the aim of helping to restore the ability within psychiatry and clinical psychology to draw qualitative distinctions between mental symptoms that are only apparently similar, thereby promoting a more precise characterization of experiential phenotypes. A wide range of mental disorders are considered in the book, each portrayed by a distinguished clinician. Each chapter begins with the description of a paradigmatic case study in order to introduce the reader directly to the patient’s lived world. The first-person perspective of the patient is the principal focus of attention. The essential, defining features of each psychopathological phenomenon and the meaning that the patient attaches to it are carefully analyzed in order to “make sense” of the patient’s apparently nonsensical experiences. In the second part of each chapter, the case study is discussed within the context of relevant literature and a detailed picture of the state of the art concerning the psychopathological understanding of the phenomenon at issue is provided. An Experiential Approach to Psychopathology, and the method it proposes, may be considered the result of convergence of classic phenomenological psychopathological concepts and updated clinical insights into patients’ lived experiences. It endorses three key principles: subjective phenomena are the quintessential feature of mental disorders; their qualitative study is mandatory; phenomenology has developed a rigorous method to grasp “what it is like” to be a person experiencing psychopathological phenomena. While the book is highly relevant for expert clinical phenomenologists, it is written in a way that will be readily understandable for trainees and young clinicians.

Psychosis

Psychosis
Author : Floriana Irtelli,Enrico Vincenti
Publisher : BoD – Books on Demand
Release Date : 2018-10-17
Category : Medical
Total pages :112
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This book collects chapters from a number of scientists all over the world, giving their contribution to the comprehension and clinical management of psychosis. The book adopts a perspective that respects the complexity of the human person and his/her relationships. It devotes a space both to the deepening of the more strictly biological aspects, the psychological aspects and the social aspects. Each section of the book (biological, psychological, social) reveals a deep connection with the themes of the other sections, showing the strength of this biopsychosocial interweaving. The relationship and the interweaving between these different areas is certainly a foundation of our existence and constitutes a law to which we cannot escape, so it is necessary that the biopsyosocial model is always considered in the interventions for the psychotic patient. This book also focuses on some specific and very innovative topics such as the importance of psychosocial factors and family factors, complementary approaches to psychosis managment, subclinical psychosis and relational aspects of psychosis.

Early Intervention in Psychotic Disorders

Early Intervention in Psychotic Disorders
Author : Tandy Miller,Sarnoff A. Mednick,Thomas H. McGlashan,Jan Libiger,Johan Olav Johannessen
Publisher : Springer Science & Business Media
Release Date : 2001-05-31
Category : Medical
Total pages :289
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The papers presented here, written by experts from all parts of the globe, describe efforts that represent a revolutionary moment in the treatment of schizophrenia disorders as, with caution, we begin to shift the standard of treatment toward early intervention and prevention. Contributions are organised according to the early course of psychosis. The book is of critical importance to anyone interested in psychotic disorders and the revolutionary impact that the field of early detection and intervention is having on traditional conceptualisations of psychotic illness.

Clinical Handbook of Schizophrenia

Clinical Handbook of Schizophrenia
Author : Kim Tornvall Mueser,Dilip V. Jeste
Publisher : Guilford Press
Release Date : 2011-01-31
Category : Psychology
Total pages :650
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Reviewing the breadth of current knowledge on schizophrenia, this handbook provides clear, practical guidelines for effective assessment and treatment in diverse contexts. Leading authorities have contributed 61 concise chapters on all aspects of the disorder and its clinical management. In lieu of exhaustive literature reviews, each chapter summarizes the state of the science; highlights key points the busy practitioner needs to know; and lists recommended resources, including seminal research studies, invaluable clinical tools, and more. Comprehensive, authoritative, and timely, the volume will enable professionals in any setting to better understand and help their patients or clients with severe mental illness.