January 27, 2021

Download Ebook Free Molecular-Genetic And Statistical Techniques For Behavioral And Neural Research

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research

Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research
Author : Robert T. Gerlai
Publisher : Academic Press
Release Date : 2018-04-24
Category : Medical
Total pages :708
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Molecular-Genetic and Statistical Techniques for Behavioral and Neural Research presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior, a critical piece of the puzzle for clinicians, scientists, course instructors and advanced undergraduate and graduate students. Chapters examine neuroinformatics, genetic and neurobehavioral databases and data mining, also providing an analysis of natural genetic variation and principles and applications of forward (mutagenesis) and reverse genetics (gene targeting). In addition, the book discusses gene expression and its role in brain function and behavior, along with ethical issues in the use of animals in genetics testing. Written and edited by leading international experts, this book provides a clear presentation of the frontiers of basic research as well as translationally relevant techniques that are used by neurobehavioral geneticists. Focuses on new techniques, including electrocorticography, functional mapping, stereo EEG, motor evoked potentials, optical coherence tomography, magnetoencephalography, laser evoked potentials, transmagnetic stimulation, and motor evoked potentials Presents the most exciting molecular and recombinant DNA techniques used in the analysis of brain function and behavior Written and edited by leading international experts

Exam Prep for: Molecular-genetic and Statistical Techniques ...

Exam Prep for: Molecular-genetic and Statistical Techniques ...
Author : Anonim
Publisher : Unknown
Release Date : 2021
Category :
Total pages :129
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Handbook of Molecular-Genetic Techniques for Brain and Behavior Research

Handbook of Molecular-Genetic Techniques for Brain and Behavior Research
Author : Wim E. Crusio,R.T. Gerlai
Publisher : Elsevier
Release Date : 1999-10-18
Category : Psychology
Total pages :962
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The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.

Handbook of Molecular-Genetic Techniques for Brain and Behavior Research

Handbook of Molecular-Genetic Techniques for Brain and Behavior Research
Author : Wim E. Crusio,R.T. Gerlai
Publisher : Elsevier
Release Date : 1999-10-18
Category : Psychology
Total pages :962
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The book gives a broad overview of recombinant DNA techniques for the behavioral neuroscientist, with illustrative examples of applications. Species covered include rodents (mainly mice), Drosophila melanogaster, Caenorhabditis elegans and Danio rerio. Experimental techniques required to characterize the behavioral phenotypes of mutant animals is provided. Several aspects of novel molecular-genetic techniques are overviewed and possible research strategies are explained. The sections of the book start with general descriptions of techniques followed by illustrative examples. It is divided into six sections. Section 1, bioinformatics and genomics research. Section 2, top-down strategies, where the researcher starts with the phenotype and then analyzes the associated genes; bottom-up strategies, where the physiological chain leading to a phenotype is analyzed starting from the gene product. Section 3, transgenic approaches in rodents including overexpressing foreign genes and gene-targeting; systemic manipulation approaches directly targeting the central nervous system and methods used with invertebrates. Section 4, methods used to evaluate relevant behavioral phenotypes, including learning and aggression. Section 5, examples on molecular brain research in man. Section 6, ethical aspects of research in this field.

Neurobehavioral Genetics

Neurobehavioral Genetics
Author : Byron C. Jones,Pierre Mormede
Publisher : CRC Press
Release Date : 2006-08-30
Category : Medical
Total pages :496
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A complete background to concepts and principles of behavioral genetics, Neurobehavioral Genetics: Methods and Applications, Second Edition features a broad spectrum of the most current techniques in neurobehavioral genetics in a single source. International researchers incorporate several new developments in the field, including: De

Handbook of Child Psychology, Theoretical Models of Human Development

Handbook of Child Psychology, Theoretical Models of Human Development
Author : William Damon,Richard M. Lerner
Publisher : John Wiley & Sons
Release Date : 2006-05-19
Category : Psychology
Total pages :1250
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Part of the authoritative four-volume reference that spans the entire field of child development and has set the standard against which all other scholarly references are compared. Updated and revised to reflect the new developments in the field, the Handbook of Child Psychology, Sixth Edition contains new chapters on such topics as spirituality, social understanding, and non-verbal communication. Volume 1: Theoretical Models of Human Development, edited by Richard M. Lerner, Tufts University, explores a variety of theoretical approaches, including life-span/life-course theories, socio-culture theories, structural theories, object-relations theories, and diversity and development theories. New chapters cover phenomenology and ecological systems theory, positive youth development, and religious and spiritual development.

Encyclopedia of Applied Developmental Science

Encyclopedia of Applied Developmental Science
Author : Celia B Fisher,Richard M. Lerner
Publisher : SAGE Publications
Release Date : 2004-10-16
Category : Psychology
Total pages :1360
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The Encyclopedia of Applied Developmental Science is an important and timely contribution to this burgeoning field. This four-volume set is the authoritative source that encompasses the entire range of concepts and topics involved in the study of applied developmental science. Its contents and levels have broad appeal for those interested in how the application of knowledge about human development can be used to enhance the lives of individuals, families, and communities.

Behavior Genetics of Cognition Across the Lifespan

Behavior Genetics of Cognition Across the Lifespan
Author : Deborah Finkel,Chandra A. Reynolds
Publisher : Springer Science & Business Media
Release Date : 2013-07-09
Category : Psychology
Total pages :300
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Along with psychopathology, cognition has been one of the primary phenotypic focal points of the field of behavior genetics since its inception. Francis Galton’s 1874 examination of eminent families in Britain was among the earliest attempts to investigate whether cognitive achievements run in families. This volume presents current methodologies for understanding cognitive abilities that move beyond the outdated nature vs. nurture paradigm. Recent advances in both collection and statistical modeling of twin data, particularly longitudinal twin data, make this an especially advantageous moment to produce a work that presents a collection of the groundbreaking research on cognitive abilities across the lifespan. This volume presents an overview of the current state of quantitative and molecular genetic investigations into the many facets of cognitive performance and functioning across the lifespan.​

Behavioral and Neural Genetics of Zebrafish

Behavioral and Neural Genetics of Zebrafish
Author : Robert T. Gerlai
Publisher : Academic Press
Release Date : 2020-04-03
Category : Medical
Total pages :614
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Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics

Biosocial Surveys

Biosocial Surveys
Author : National Research Council,Division of Behavioral and Social Sciences and Education,Committee on Population,Committee on Advances in Collecting and Utilizing Biological Indicators and Genetic Information in Social Science Surveys
Publisher : National Academies Press
Release Date : 2008-01-06
Category : Social Science
Total pages :428
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Biosocial Surveys analyzes the latest research on the increasing number of multipurpose household surveys that collect biological data along with the more familiar interviewerâ€"respondent information. This book serves as a follow-up to the 2003 volume, Cells and Surveys: Should Biological Measures Be Included in Social Science Research? and asks these questions: What have the social sciences, especially demography, learned from those efforts and the greater interdisciplinary communication that has resulted from them? Which biological or genetic information has proven most useful to researchers? How can better models be developed to help integrate biological and social science information in ways that can broaden scientific understanding? This volume contains a collection of 17 papers by distinguished experts in demography, biology, economics, epidemiology, and survey methodology. It is an invaluable sourcebook for social and behavioral science researchers who are working with biosocial data.

What's Wrong With My Mouse?

What's Wrong With My Mouse?
Author : Jacqueline N. Crawley
Publisher : John Wiley & Sons
Release Date : 2007-05-11
Category : Science
Total pages :544
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Dr. Jacqueline N. Crawley, author of the First and Second Editions of What’s Wrong with My Mouse? Behavioral Phenotyping of Transgenic and Knockout Mice,continues to field calls and e-mails from molecular geneticists who ask: how do I run behavioral assays to find out what’s wrong with my mouse? Turn to What’s Wrong with My Mouse? to discover the wealth of mouse behavioral tasks and to get the guidance you need to select the best methods and necessary controls. Chapters are organized by behavioral domain, including measurements of general health, motor functions, sensory abilities, learning and memory, feeding and drinking, reproductive, social, emotional, and reward behaviors in mutant mice. Throughout the chapters, new behavioral tasks and new research discoveries have been added, bringing the Second Edition up to date with the latest science. In addition, the Second Edition includes two new chapters: "Neurodevelopment and Neurodegeneration" discusses mouse behavioral tasks relevant to neurodevelopmental diseases, such as mental retardation and autism, and to neurodegenerative diseases, such as Alzheimers, Parkinsons, Huntingtons, and amyotrophic lateral sclerosis. "Putting It All Together" recommends strategies for optimizing a battery of behavioral phenotyping tests to address your specific hypotheses about gene functions. The final chapter, "The Next Generation," examines new and emerging technologies. Throughout the book, the use of behavioral testing equipment is illustrated with photographs, diagrams, and representative data. Examples of behavioral tasks successfully applied to transgenic and knockout mouse models are provided, as well as references to the primary literature and step-by-step methods protocols. These features, along with a comprehensive index, listings of database and vendor websites, and an extensive list of references, make this book a valuable and practical resource for students and researchers.

American Book Publishing Record

American Book Publishing Record
Author : Anonim
Publisher : Unknown
Release Date : 2003
Category : American literature
Total pages :129
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Directory of Research Grants 2005

Directory of Research Grants 2005
Author : Jeremy T. Miner,Lynn E. Miner,Greenwood-Heinemann Publishing
Publisher : Oryx Press
Release Date : 2004
Category : Education
Total pages :912
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A treasure chest of information on more than 5,100 current programs from 1,880 sponsors. Find grants for basic research, equipment acquisition, building construction/renovation, fellowships, and 23 other program types.

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry

Genomics, Circuits, and Pathways in Clinical Neuropsychiatry
Author : Thomas Lehner,Bruce L. Miller,Matthew W. State
Publisher : Academic Press
Release Date : 2016-06-07
Category : Science
Total pages :796
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This foundational work comprehensively examines the current state of the genetics, genomics and brain circuitry of psychiatric and neurological disorders. It consolidates discoveries of specific genes and genomic regions associated with these conditions, the genetic and anatomic architecture of these syndromes, and addresses how recent advances in genomics are leading to a reappraisal of the biology underlying clinical neuroscience. In doing so, it critically examines the promise and limitations of these discoveries toward treatment, and to the interdisciplinary nature of understanding brain and behavior. Coverage includes new discoveries regarding autism, epilepsy, intellectual disability, dementias, movement disorders, language impairment, disorders of attention, schizophrenia, and bipolar disorder. Genomics, Circuits, and Pathways in Clinical Neuropsychiatry focuses on key concepts, challenges, findings, and methods in genetics, genomics, molecular pathways, brain circuitry, and related neurobiology of neurologic and psychiatric disorders. Provides interdisciplinary appeal in psychiatry, neurology, neuroscience, and genetics Identifies key concepts, methods, and findings Includes coverage of multiple disorders from autism to schizophrenia Reviews specific genes associated with disorders Discusses the genetic architecture of these syndromes Explains how recent findings are influencing the understanding of biology Clarifies the promise of these findings for future treatment

Behavioral Genetics in the Postgenomic Era

Behavioral Genetics in the Postgenomic Era
Author : Robert Plomin
Publisher : Amer Psychological Assn
Release Date : 2003
Category : Medical
Total pages :608
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The Human Genome Project-which has provided a working draft of the sequence of DNA in the human genome - is a remarkable scientific achievement. In this postgenomic world, it appears that all genes and all DNA variation will eventually be known. For behavioral researchers, this is especially exciting because behavioral dimensions and disorders are the most complex traits of all. To understand these traits, we need to understand the roles of many genes and many environmental influences.