April 13, 2021

Download Ebook Free Molecular Photofitting

Molecular Photofitting

Molecular Photofitting
Author : Tony Frudakis, Ph.D.
Publisher : Elsevier
Release Date : 2010-07-19
Category : Social Science
Total pages :712
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In the field of forensics, there is a critical need for genetic tests that can function in a predictive or inferential sense, before suspects have been identified, and/or for crimes for which DNA evidence exists but eye-witnesses do not. Molecular Photofitting fills this need by describing the process of generating a physical description of an individual from the analysis of his or her DNA. The molecular photofitting process has been used to assist with the identification of remains and to guide criminal investigations toward certain individuals within the sphere of prior suspects. Molecular Photofitting provides an accessible roadmap for both the forensic scientist hoping to make use of the new tests becoming available, and for the human genetic researcher working to discover the panels of markers that comprise these tests. By implementing population structure as a practical forensics and clinical genomics tool, Molecular Photofitting serves to redefine the way science and history look at ancestry and genetics, and shows how these tools can be used to maximize the efficacy of our criminal justice system. Explains how physical descriptions of individuals can be generated using only their DNA Contains case studies that show how this new forensic technology is used in practical application Includes over 100 diagrams, tables, and photos to illustrate and outline complex concepts

A Genetic Assay for Estimating Scalp Hair Pigmentation from Forensic Specimens

A Genetic Assay for Estimating Scalp Hair Pigmentation from Forensic Specimens
Author : Sara Lynn Jubelirer
Publisher : Unknown
Release Date : 2010
Category : DNA
Total pages :210
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Genetics and the Unsettled Past

Genetics and the Unsettled Past
Author : Keith Wailoo,Alondra Nelson,Catherine Lee
Publisher : Rutgers University Press
Release Date : 2012-03-15
Category : Medical
Total pages :370
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Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to perform a kind of racially charged cultural work: to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present. Genetics and the Unsettled Past considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history. This unique collection brings together scholars from a wide range of disciplines—biology, history, cultural studies, law, medicine, anthropology, ethnic studies, sociology—to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, Native Americans, South Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.

Library Journal

Library Journal
Author : Melvil Dewey,Richard Rogers Bowker,L. Pylodet,Charles Ammi Cutter,Bertine Emma Weston,Karl Brown,Helen E. Wessells
Publisher : Unknown
Release Date : 2007
Category : Libraries
Total pages :129
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Includes, beginning Sept. 15, 1954 (and on the 15th of each month, Sept.-May) a special section: School library journal, ISSN 0000-0035, (called Junior libraries, 1954-May 1961). Also issued separately.

Handbook of Forensic Anthropology and Archaeology

Handbook of Forensic Anthropology and Archaeology
Author : Soren Blau,Douglas H. Ubelaker
Publisher : Routledge
Release Date : 2016-07-28
Category : Social Science
Total pages :696
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With contributions from 70 experienced practitioners from around the world, this second edition of the authoritative Handbook of Forensic Archaeology and Anthropology provides a solid foundation in both the practical and ethical components of forensic work. The book weaves together the discipline’s historical development; current field methods for analyzing crime, natural disasters, and human atrocities; an array of laboratory techniques; key case studies involving legal, professional, and ethical issues; and ideas about the future of forensic work--all from a global perspective. This fully revised second edition expands the geographic representation of the first edition by including chapters from practitioners in South Africa and Colombia, and adds exciting new chapters on the International Commission on Missing Persons and on forensic work being done to identify victims of the Battle of Fromelles during World War I. The Handbook of Forensic Anthropology and Archaeology provides an updated perspective of the disciplines of forensic archaeology and anthropology.

Ancestors and Relatives

Ancestors and Relatives
Author : Eviatar Zerubavel
Publisher : OUP USA
Release Date : 2012-01-26
Category : Reference
Total pages :226
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Noted social scientist Eviatar Zerubavel casts a critical eye on how we trace our past-individually and collectively arguing that rather than simply find out who our ancestors are from genetics or history, we actually create the stories that make them our ancestors.

New Scientist

New Scientist
Author : Anonim
Publisher : Unknown
Release Date : 2009
Category : Science
Total pages :129
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Technology in Forensic Science

Technology in Forensic Science
Author : Deepak Rawtani,Chaudhery Mustansar Hussain
Publisher : John Wiley & Sons
Release Date : 2020-11-02
Category : Medical
Total pages :416
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The book "Technology in Forensic Science" provides an integrated approach by reviewing the usage of modern forensic tools as well as the methods for interpretation of the results. Starting with best practices on sample taking, the book then reviews analytical methods such as high-resolution microscopy and chromatography, biometric approaches, and advanced sensor technology as well as emerging technologies such as nanotechnology and taggant technology. It concludes with an outlook to emerging methods such as AI-based approaches to forensic investigations.

Drug-like Properties: Concepts, Structure Design and Methods

Drug-like Properties: Concepts, Structure Design and Methods
Author : Li Di,Edward H Kerns
Publisher : Elsevier
Release Date : 2010-07-26
Category : Science
Total pages :552
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Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. This book is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties. * Serves as an essential working handbook aimed at scientists and students in medicinal chemistry * Provides practical, step-by-step guidance on property fundamentals, effects, structure-property relationships, and structure modification strategies * Discusses improvements in pharmacokinetics from a practical chemist's standpoint

Juvenile Osteology

Juvenile Osteology
Author : Louise Scheuer,Sue Black,Maureen C. Schaefer
Publisher : Academic Press
Release Date : 2010-07-28
Category : Law
Total pages :384
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The need for a laboratory and field manual to assist with the evaluation of juvenile skeletal material is long overdue. This resource is essential for the practising osteoarchaeologist and forensic anthropologist who requires a quick, reliable and easy-to-use reference to aid in the identification, siding and aging of juvenile osseous material. While excellent reference books on juvenile osteology are currently available, no pre-existing source adequately fills this particular niche in the market. This field manual is designed with practicality as its primary directive. Descriptions of each bone contain 1) morphological characteristics useful for identification, 2) other elements with which the bone may be confused, 2) tips for siding, 3) illustrations of varying developmental phases, 4) data useful for ageing, and 5) a summary of developmental timings. Concise, bullet-style descriptions assist with quick retrieval of information. Unique to this manual is the presentation of data collected from a variety of populations, utilizing a range of observational methods, as an alternative to providing one overall aging summary that is derived from a compilation of many individual sources. This manual provides a host of data on a variety of populations to enable the user to select the reference most applicable to their needs. The final chapter combines information from each bone to provide a summary of developmental changes occurring at different life stages to act as an immediate 'ready reckoner' for the knowledgeable practitioner. It also provides forms useful for documenting juvenile material and diagrams to help with the recognition of commingled juvenile remains. The manual is a must for anyone responsible for the evaluation of juvenile osseous material through dry bone assessment, radiographs, sonograms, and or CT scans. *Identifies every component of the developing skeleton *Provides detailed analysis of juvenile skeletal remains and the development of bone as a tissue *Summarizes key morphological stages in the development of every bone *Provides data on a variety of populations to enable the user to select the reference most applicable to their needs *Focuses on practicality, with direct, bullet style descriptions *Provides forms for documenting juvenile material *Provides diagrams to help with the recognition of commingled juvenile remains *Final chapter provides summary of developmental changes occurring at different life stages to act as an immediate 'ready reckoner' for the practitioner

Parkinson's Disease

Parkinson's Disease
Author : Richard Nass,Serge Przedborski
Publisher : Elsevier
Release Date : 2011-04-28
Category : Psychology
Total pages :686
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Parkinson’s disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely recapitulate the disease state. The identification of a number of genes thought to play a role in the cell death, and development of both toxin and genetic models to explore the function of the genes both in unaffected and diseased cells are now providing new insights into the molecular basis of the neurodegeneration, as well as therapeutic approaches. In this reference, we will describe the advances and the advantages that various invertebrates, cell culture, rodents, and mammals provide in the identification of the molecular components and mechanisms involved in the cell death, and outline the opportunities that these systems provide in drug discovery. Comprehensive and critical assessment of the utility of various model systems to identify the molecular components and pathways involved in Parkinson’s disease Describes the power of toxin and genetic models to identify novel therapeutic targets and compounds that can be used in PD Current overviews of current status of PD research and discovery from bench-to-bedside Provides novel insights and views on where the future of PD research may lead Provides a powerful teaching tool and template to explore the utility of model systems to identify molecular pathways, molecular targets, and therapeutics that are applicable to a variety of neurological diseases

Crime Reconstruction

Crime Reconstruction
Author : W. Jerry Chisum,Brent E. Turvey
Publisher : Academic Press
Release Date : 2011-08-09
Category : Social Science
Total pages :704
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Crime Reconstruction, Second Edition is an updated guide to the interpretation of physical evidence, written for the advanced student of forensic science, the practicing forensic generalist and those with multiple forensic specialists. It is designed to assist reconstructionists with understanding their role in the justice system; the development and refinement of case theory’ and the limits of physical evidence interpretation. Chisum and Turvey begin with chapters on the history and ethics of crime reconstruction and then shift to the more applied subjects of reconstruction methodology and practice standards. The volume concludes with chapters on courtroom conduct and evidence admissibility to prepare forensic reconstructionists for what awaits them when they take the witness stand. Crime Reconstruction, Second Edition, remains an unparalleled watershed collaborative effort by internationally known, qualified, and respected forensic science practitioner holding generations of case experience among them. Forensic pioneer such as W. Jerry Chisum, John D. DeHaan, John I. Thorton, and Brent E. Turvey contribute chapters on crime scene investigation, arson reconstruction, trace evidence interpretation, advanced bloodstain interpretation, and ethics. Other chapters cover the subjects of shooting incident reconstruction, interpreting digital evidence, staged crime scenes, and examiner bias. Rarely have so many forensic giants collaborated, and never before have the natural limits of physical evidence been made so clear. Updates to the majority of chapters, to comply with the NAS Report New chapters on forensic science, crime scene investigation, wound pattern analysis, sexual assault reconstruction, and report writing Updated with key terms, chapter summaries, discussion questions, and a comprehensive glossary; ideal for those teaching forensic science and crime reconstruction subjects at the college level Provides clear practice standards and ethical guidelines for the practicing forensic scientist

Race Decoded

Race Decoded
Author : Catherine Bliss
Publisher : Stanford University Press
Release Date : 2012-05-23
Category : Social Science
Total pages :280
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In 2000, with the success of the Human Genome Project, scientists declared the death of race in biology and medicine. But within five years, many of these same scientists had reversed course and embarked upon a new hunt for the biological meaning of race. Drawing on personal interviews and life stories, Race Decoded takes us into the world of elite genome scientists—including Francis Collins, director of the NIH; Craig Venter, the first person to create a synthetic genome; and Spencer Wells, National Geographic Society explorer-in-residence, among others—to show how and why they are formulating new ways of thinking about race. In this original exploration, Catherine Bliss reveals a paradigm shift, both at the level of science and society, from colorblindness to racial consciousness. Scientists have been fighting older understandings of race in biology while simultaneously promoting a new grand-scale program of minority inclusion. In selecting research topics or considering research design, scientists routinely draw upon personal experience of race to push the public to think about race as a biosocial entity, and even those of the most privileged racial and social backgrounds incorporate identity politics in the scientific process. Though individual scientists may view their positions differently—whether as a black civil rights activist or a white bench scientist—all stakeholders in the scientific debates are drawing on memories of racial discrimination to fashion a science-based activism to fight for social justice.

Forensic Facial Identification

Forensic Facial Identification
Author : Tim Valentine,Josh P Davis
Publisher : John Wiley & Sons
Release Date : 2015-06-22
Category : Psychology
Total pages :376
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Forensic Facial Identification discusses the latest scientific and technical advancements in the field and their implications for practice in psychology, criminology, and law. Provides an up-to-date set of best practices for forensic facial identification Reviews current procedures for different facial identification methods and their reliability Covers eyewitness testimony, line-ups, facial composites, anthropological face reconstructions, CCTV images, and computerized automatic face recognition systems Incorporates case studies which put the latest research and technology in the proper legal context

Craniofacial Identification

Craniofacial Identification
Author : Caroline Wilkinson,Christopher Rynn
Publisher : Cambridge University Press
Release Date : 2012-05-03
Category : Nature
Total pages :263
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Draws together a wide range of elements relating to craniofacial analysis and identification, examining the latest advances in the field.