June 20, 2021

Download Ebook Free Neuroscience Of Alcohol

Alcohol and the Nervous System

Alcohol and the Nervous System
Author : Edith V. Sullivan,Adolf Pfefferbaum
Publisher : Elsevier
Release Date : 2014-10-08
Category : Science
Total pages :704
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Alcohol is the most widely used drug in the world, yet alcoholism remains a serious addiction affecting nearly 20 million Americans. Our current understanding of alcohol's effect on brain structure and related functional damage is being revolutionized by genetic research, basic neuroscience, brain imaging science, and systematic study of cognitive, sensory, and motor abilities. Volume 125 of the Handbook of Clinical Neurology is a comprehensive, in-depth treatise of studies on alcohol and the brain covering the basic understanding of alcohol's effect on the central nervous system, the diagnosis and treatment of alcoholism, and prospect for recovery. The chapters within will be of interest to clinical neurologists, neuropsychologists, and researchers in all facets and levels of the neuroscience of alcohol and alcoholism. The first focused reference specifically on alcohol and the brain Details our current understanding of how alcohol impacts the central nervous system Covers clinical and social impact of alcohol abuse disorders and the biomedical consequences of alcohol abuse Includes section on neuroimaging of neurochemical markers and brain function

Neuroscience of Alcohol

Neuroscience of Alcohol
Author : Victor R. Preedy
Publisher : Academic Press
Release Date : 2019-03-19
Category : Medical
Total pages :736
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Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of alcohol use, along with its effects on neurobiological function Discusses alcohol use as a component of dual-use and poly addictions Outlines numerous screening and treatment strategies for alcohol misuse Covers both the physical and psychological effects of alcohol use and withdrawals to provide a fully-formed view of alcohol dependency and its effects

Neuroscience: Pathways to Alcohol Dependence: Part I -- Overview of the Neurobiology of Dependence

Neuroscience: Pathways to Alcohol Dependence: Part I -- Overview of the Neurobiology of Dependence
Author : Edith V. Sullivan
Publisher : Unknown
Release Date : 2009-05
Category :
Total pages :283
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Contents: Neurobiology of Alcohol Dependence: Focus on Motivational Mechanisms; Communication Networks in the Brain: Neurons, Receptors, Neurotransmitters, and Alcohol; Translational Studies of Alcoholism: Bridging the Gap; Strategies to Study the Neuroscience of Alcoholism; Positron Emission Tomography as a Tool for Studying Alcohol Abuse; From Event-Related Potential to Oscillations: Genetic Diathesis in Brain (Dys)Function and Alcohol Dependence; The Use of Magnetic Resonance Spectroscopy and Magnetic Resonance Imaging in Alcohol Research; Magnetic Resonance Imaging Approaches for Studying Alcoholism Using Mouse Models; Laser-Assisted Microdissection; Proteomic Solutions for Analytical Challenges Associated with Alcohol Research; On the Use of Short-Interfering RNA to Study Alcohol-Related Genes; Viral Delivery of Small-Hairpin RNAs for Reducing Gene Expression in the Rodent Brain; Quantitative Trait Locus Analysis: Multiple Cross and Heterogeneous Stock Mapping; Interval-Specific Congenic Animals for High-Resolution Quantitative Trait Loci Mapping; Single-Nucleotide Polymorphism Masking; Expression Quantitative Trait Loci and the PhenoGen Database; Integrative Genetic Analysis of Alcohol Dependence; Using the GeneNetwork Web Resources; Conclusions; Glossary. Illus.

Neurobiology of Alcohol Dependence

Neurobiology of Alcohol Dependence
Author : Antonio Noronha,Changhai Cui,Robert Adron Harris,John C. Crabbe
Publisher : Elsevier
Release Date : 2014-05-02
Category : Science
Total pages :566
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Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. Neurobiology of Alcohol Dependence highlights the most recent data at the molecular, cellular, neurocircuitry, and behavioral levels, fostering an understanding how neuroplasticity and neuroadaptation occur, and how different neural pathways and neurocircuits contribute to dependence. Highlights recent advances in understanding alcohol addiction from molecular, cellular, neurocircuitry, and behavioral levels Integrates several emerging areas of research and discusses the application of novel research techniques to the understanding of alcohol dependence Chapters authored by leaders in the field around the globe — the broadest, most expert coverage available

Neuroscience

Neuroscience
Author : National Institute on Alcohol Abuse and Alcoholism (U.S.)
Publisher : Unknown
Release Date : 2009
Category : Alcohol
Total pages :5
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"Neuroscience is showing that the pathways of addiction are based in the brain. Using advanced techniques such as imaging methods and studies with animal models, researchers are learning more about how alcohol interacts with the brain's communication system in different people. Innovative technology also is helping identify the changes that occur in the brain's structure and function as a result of drinking, and how alcohol disrupts the brain's delicate chemical balance. This information may help scientists understand why and how alcoholism develops in different populations and ultimately result in more effective and targeted therapies for alcohol abuse and dependence."--Conclusion.

Never Enough

Never Enough
Author : Judith Grisel
Publisher : Anchor
Release Date : 2019-02-19
Category : Psychology
Total pages :256
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A NEW YORK TIMES BESTSELLER From a renowned behavioral neuroscientist and recovering addict, a rare page-turning work of science that draws on personal insights to reveal how drugs work, the dangerous hold they can take on the brain, and the surprising way to combat today's epidemic of addiction. Judith Grisel was a daily drug user and college dropout when she began to consider that her addiction might have a cure, one that she herself could perhaps discover by studying the brain. Now, after twenty-five years as a neuroscientist, she shares what she and other scientists have learned about addiction, enriched by captivating glimpses of her personal journey. In Never Enough, Grisel reveals the unfortunate bottom line of all regular drug use: there is no such thing as a free lunch. All drugs act on the brain in a way that diminishes their enjoyable effects and creates unpleasant ones with repeated use. Yet they have their appeal, and Grisel draws on anecdotes both comic and tragic from her own days of using as she limns the science behind the love of various drugs, from marijuana to alcohol, opiates to psychedelics, speed to spice. With more than one in five people over the age of fourteen addicted, drug abuse has been called the most formidable health problem worldwide, and Grisel delves with compassion into the science of this scourge. She points to what is different about the brains of addicts even before they first pick up a drink or drug, highlights the changes that take place in the brain and behavior as a result of chronic using, and shares the surprising hidden gifts of personality that addiction can expose. She describes what drove her to addiction, what helped her recover, and her belief that a “cure” for addiction will not be found in our individual brains but in the way we interact with our communities. Set apart by its color, candor, and bell-clear writing, Never Enough is a revelatory look at the roles drugs play in all of our lives and offers crucial new insight into how we can solve the epidemic of abuse.

Neurobiology of Addiction

Neurobiology of Addiction
Author : George F. Koob,Michel Le Moal
Publisher : Elsevier
Release Date : 2005-11-11
Category : Psychology
Total pages :504
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Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neurobiological mechanism of action for each drug class at the molecular, cellular and neurocircuitry level of analysis. A chapter on neuroimaging and drug addiction provides a synthesis of exciting new data from neuroimaging in human addicts — a unique perspective unavailable from animal studies. The final chapters explore theories of addiction at the neurobiological and neuroadaptational level both from a historical and integrative perspective. The book incorporates diverse finding with an emphasis on integration and synthesis rather than discrepancies or differences in the literature. · Presents a unique perspective on addiction that emphasizes molecular, cellular and neurocircuitry changes in the transition to addiction · Synthesizes diverse findings on the neurobiology of addiction to provide a heuristic framework for future work · Features extensive documentation through numerous original figures and tables that that will be useful for understanding and teaching

Methods in Alcohol-Related Neuroscience Research

Methods in Alcohol-Related Neuroscience Research
Author : Yuan Liu,David M. Lovinger
Publisher : CRC Press
Release Date : 2002-02-14
Category : Medical
Total pages :416
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Neuroscience research in alcohol-related disorders has made remarkable progress in the last two decades. The advances are due, in great part, to the large array of powerful biomedical, bioengineering, and computational biological techniques that are now employed. To date, there has not been a comprehensive text that covers recently develope

Introduction to Addiction

Introduction to Addiction
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release Date : 2019-06-11
Category : Medical
Total pages :278
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Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse. Provides neurobiological theories on how addiction works Explains addiction cycle stages of binge, withdrawal and anticipation Reviews the role of dopamine and the frontal cortex in addiction Discusses the neurocircuitry of reward and stress Includes animal models and neuroadaptational views on addiction

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption

The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption
Author : Anonim
Publisher : Academic Press
Release Date : 2017-10-31
Category : Science
Total pages :304
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The Role of Neuropeptides in Addiction and Disorders of Excessive Consumption, Volume 136 in the International Review of Neurobiology series, provides an overview of the top candidate neuropeptides in the modulation of alcohol and drug abuse, also covering eating disorders and obesity. Topics covered in this latest release include Corticotropin Releasing Factor (CRF) and Addictive Behaviors, Dynorphin/Kappa Opioid Receptor Signaling in Pre-clinical Models of Alcohol, Drug, and Food Addiction, The Role of Ghrelin Signaling in Additive Behaviors, The Role of the Melanocortin System in Drug and Eating Disorders, Substance P and the Neurokinin-1 Receptor: The New CRH, and the Role of Neuropeptide Y (NPY) in Drug and Eating Disorders. The book uniquely highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders. Presents a recent overview of some of the top candidate neuropeptides in the modulation of alcohol and drug abuse, and in eating disorders and obesity Highlights the overlapping central mechanisms that contribute to both drug and alcohol abuse and eating disorders Contains chapters that focus on a specific neuropeptide

Alcohol Addiction

Alcohol Addiction
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release Date : 2021-03-01
Category : Psychology
Total pages :350
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Alcohol Addiction, Volume Three in the Neurobiology of Addiction series, provides a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction. Sections differentiate alcohol use, alcohol abuse and alcohol addiction, providing a clear path on how alcohol abuse can develop into an addiction. This volume includes thorough descriptions of the physiological and behavioral effects of alcohol abuse and addiction. In addition, the book clearly defines the neurobiological effects of alcohol into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage, and last the Preoccupation/Anticipation Stage. Highlights recent advances in our understanding of alcohol addiction Includes information regarding molecular, cellular, neurocircuitry and behavioral levels of alcohol addiction Clearly outlines alcohol abuse vs. alcohol addiction Defines the neurobiological effects of alcohol addiction in three clear stages

Alcohol Addiction

Alcohol Addiction
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release Date : 2021-03-15
Category : Psychology
Total pages :350
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A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction is detailed in Neurobiology of Addiction series, each volume addressing a specific area of addiction. Neurobiology of Alcohol Addiction, Volume 2 in the series, differentiates alcohol use, alcohol abuse and alcohol addiction, providing a clear path on how alcohol abuse can develop into an addiction. This volume includes thorough descriptions of the physiological and behavioral effects of alcohol abuse and addiction. In addition, the book clearly defines the neurobiological effects of alcohol into three distinct steps: Binge/Intoxication Stage, Withdrawal/Negative Affect Stage and last the Preoccupation/Anticipation Stage Highlights recent advances in understanding alcohol addiction Includes information regarding molecular, cellular, neurocircuitry, and behavioral levels of alcohol addictio Clearly outlines alcohol abuse vs alcohol addiction Defines neurobiological effects of alcohol addiction into 3 clear stages

Drugs, Addiction, and the Brain

Drugs, Addiction, and the Brain
Author : George F. Koob,Michael A. Arends,Michel Le Moal
Publisher : Academic Press
Release Date : 2014-07-12
Category : Psychology
Total pages :350
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Drugs, Addiction, and the Brain explores the molecular, cellular, and neurocircuitry systems in the brain that are responsible for drug addiction. Common neurobiological elements are emphasized that provide novel insights into how the brain mediates the acute rewarding effects of drugs of abuse and how it changes during the transition from initial drug use to compulsive drug use and addiction. The book provides a detailed overview of the pathophysiology of the disease. The information provided will be useful for neuroscientists in the field of addiction, drug abuse treatment providers, and undergraduate and postgraduate students who are interested in learning the diverse effects of drugs of abuse on the brain. Full-color circuitry diagrams of brain regions implicated in each stage of the addiction cycle Actual data figures from original sources illustrating key concepts and findings Introduction to basic neuropharmacology terms and concepts Introduction to numerous animal models used to study diverse aspects of drug use. Thorough review of extant work on the neurobiology of addiction

Neural-Immune Interactions in Brain Function and Alcohol Related Disorders

Neural-Immune Interactions in Brain Function and Alcohol Related Disorders
Author : Changhai Cui,Lindsey Grandison,Antonio Noronha
Publisher : Springer Science & Business Media
Release Date : 2012-11-14
Category : Medical
Total pages :588
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Recent studies have provided clear evidence on the role of neural-immune interactions in normal brain function and neuropathological conditions. Neuroimmune factors, which play an essential role in neuroinflammatory response, have been implicated in the regulation of neuronal function and plasticity. Thus, neural-immune interactions provide a new frame work for understanding the role of the neuroimmune system in normal brain function, neurodevelopment, and a variety of neurological disorders. These advances have a far reaching impact on many areas of neuroscience, including alcohol research. Studies using human alcoholic brains, gene knockout mice, and gene expression profiling have established a clear link between alcoholism and an altered neuroimmune profile. This book integrates emerging knowledge on neural-immune interactions with key discoveries in alcohol research and provides a comprehensive overview of neural-immune interactions in brain function and behavior associated with alcohol use disorders. While Neural–Immune Interaction in Brain Function and Alcohol Related Disorders focuses on neural-immune interactions in areas directly related to alcohol use disorders, it is not intended to be all inclusive. Several areas, including sleep disorders, pain, and cholinergic anti-inflammatory pathways, are not covered as independent chapters but briefly mentioned in the text. The close relevance of these topics to neural-immune interactions and alcohol use disorders warrants future discussion and more research efforts.

Psychostimulants

Psychostimulants
Author : George F. Koob,Michael A. Arends,Mandy L. McCracken,Michel Le Moal
Publisher : Academic Press
Release Date : 2020-05-05
Category : Psychology
Total pages :262
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A current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction are detailed in our Neurobiology of Addiction series, each volume addressing a specific area of addiction. Psychostimulants, Volume 2 in the series, explores the molecular and cellular systems in the brain responsible for psychostimulant addiction, including both direct/indirect sympathomimetics and nonsympathomimetics. This volume introduces the readers to the history of psychostimulant use. The authors clearly differentiate the neurobiological effects into three distinct stages of the addiction cycle: binge/intoxication, withdrawal/negative affect, and preoccupation/anticipation. Highlights recent advances in psychostimulant addiction Includes neurocircuitry, cellular and molecular neurobiological mechanisms of psychostimulant addiction Defines the abuse and addiction potentials of both direct and indirect sympathomimetics and nonsympathomimetics