November 26, 2020

Download Ebook Free Neurotherapeutics In The Era Of Translational Medicine

Neurotherapeutics in the Era of Translational Medicine

Neurotherapeutics in the Era of Translational Medicine
Author : Richard A. Smith,Brian Kaspar,Clive Svendsen
Publisher : Academic Press
Release Date : 2020-12-01
Category : Medical
Total pages :514
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Neurotherapeutics in the Era of Translational Medicine focuses on the remarkable progress made in treating neurologic disorders which heretofore have been considered incurable. The book represents a celebration of this unique epoch in America that dates from the 1980’s, when it became possible to clone genes, and perhaps more importantly, with the sequencing of the entire human genome. Chapters include translational research in potential therapies for Alzheimer’s Disease, Amyotrophic Lateral Sclerosis‎, Spinal Muscular Atrophy, Huntington’s disease, Multiple Sclerosis, Parkinson’s Disease Myotonic Dystrophy, and Glioblastoma. The book also discusses general concerns of clinical trials, like trial designs and ethical issues. Neuroscientists, pharmacologists, and clinicians, especially neurologists and neurosurgeons will find this book useful. Comprehensive review on the progress of translational research in neurotherapeutics for neurologic disorders Discusses important issues in clinical trials such as design and ethical issues Written for neuroscientists, neurologists and pharmacologists

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2007: Testimony of members of Congress and other interested individuals and organizations

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2007: Testimony of members of Congress and other interested individuals and organizations
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release Date : 2006
Category : United States
Total pages :129
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Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2007

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 2007
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release Date : 2006
Category : United States
Total pages :129
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Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness

Mind Fixers: Psychiatry's Troubled Search for the Biology of Mental Illness
Author : Anne Harrington
Publisher : W. W. Norton & Company
Release Date : 2019-04-16
Category : Psychology
Total pages :384
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Mind Fixers tells the history of psychiatry’s quest to understand the biological basis of mental illness and asks where we need to go from here. In Mind Fixers, Anne Harrington, author of The Cure Within, explores psychiatry’s repeatedly frustrated struggle to understand mental disorder in biomedical terms. She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds. But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time. Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well. In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones. A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

Encyclopedia of Tissue Engineering and Regenerative Medicine

Encyclopedia of Tissue Engineering and Regenerative Medicine
Author : Anonim
Publisher : Academic Press
Release Date : 2019-06-04
Category : Science
Total pages :1418
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Encyclopedia of Tissue Engineering and Regenerative Medicine provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the fields of tissue engineering and regenerative medicine Contains multimedia features, including hyperlinked references and further readings, cross-references and diagrams/images Represents the most comprehensive and exhaustive product on the market on the topic

Brain Mapping

Brain Mapping
Author : Anonim
Publisher : Academic Press
Release Date : 2015-02-14
Category : Science
Total pages :2658
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Brain Mapping: A Comprehensive Reference offers foundational information for students and researchers across neuroscience. With over 300 articles and a media rich environment, this resource provides exhaustive coverage of the methods and systems involved in brain mapping, fully links the data to disease (presenting side by side maps of healthy and diseased brains for direct comparisons), and offers data sets and fully annotated color images. Each entry is built on a layered approach of the content – basic information for those new to the area and more detailed material for experienced readers. Edited and authored by the leading experts in the field, this work offers the most reputable, easily searchable content with cross referencing across articles, a one-stop reference for students, researchers and teaching faculty. Broad overview of neuroimaging concepts with applications across the neurosciences and biomedical research Fully annotated color images and videos for best comprehension of concepts Layered content for readers of different levels of expertise Easily searchable entries for quick access of reputable information Live reference links to ScienceDirect, Scopus and PubMed

Genetics of Epilepsy

Genetics of Epilepsy
Author : Anonim
Publisher : Elsevier
Release Date : 2014-09-04
Category : Science
Total pages :346
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The book chapters cover different aspects of epilepsy genetics, starting with the "classical" concept of epilepsies as ion channel disorders. The second part of the book gives credit to the fact that by now non-ion channel genes are recognized as equally important causes of epilepsy. The concluding chapters are designed to offer the reader insight into current methods in epilepsy research. Each chapter is self-contained and deals with a selected topic of interest. Authors are the leading experts in the field of epilepsy research Book covers the most important aspects of epilepsy Interesting for both scientists and clinicians

Textbook of Neural Repair and Rehabilitation

Textbook of Neural Repair and Rehabilitation
Author : Michael Selzer,Stephanie Clarke,Leonardo Cohen,Gert Kwakkel,Robert Miller
Publisher : Cambridge University Press
Release Date : 2014-04-24
Category : Medical
Total pages :688
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Volume 1 of the Textbook of Neural Repair and Rehabilitation covers the basic sciences relevant to recovery of function following injury to the nervous system.

Regenerative Pharmacology

Regenerative Pharmacology
Author : George J. Christ,Karl-Erik Andersson
Publisher : Cambridge University Press
Release Date : 2013-04-15
Category : Medical
Total pages :129
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Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Depression For Dummies

Depression For Dummies
Author : Laura L. Smith,Charles H. Elliott
Publisher : John Wiley & Sons
Release Date : 2011-04-22
Category : Self-Help
Total pages :384
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"What do you have to be depressed about?" Bet you've heard that one before. Or how about, "You're depressed? Just get over it!" Easier said than done, right? Or here's a favorite, "They have a pill for that now, you know." Unfortunately, such naïve armchair psychology rarely works for someone suffering from the very real plight of depression. All it does is seek to trivialize depression and characterize depressed people as "whiners" who have nothing better to do than to "complain about their lives." But the truth is, depression is a very real problem. In fact, the World Health Organization estimates that, on any given day, 121 million people worldwide suffer from depression. And depression rates continue to increase – for example, kids exhibit depression at nearly ten times the rate of previous generations. Theories abound as to why depression rates are increasing, but regardless of the cause, this scourge continues to rob its victims of happiness, joy, and the capacity to give and receive love. So why Depression For Dummies, when there's already a glut of self-help books on the market peddling so-called cures and remedies for depression? Because this book satisfies the need for a straight-talking, no-nonsense resource on depression. The only agenda of Depression For Dummies is to present you with the facts on depression and explain the options for dealing with it. Rest assured, this is no infomercial in a yellow and black cover. Here's just a sampling of what you'll find in Depression For Dummies: Demystifying the types of depression Discovering what goes on in the body of a depressed person Detecting and diagnosing depression Seeking help through therapy and medication Modifying depressed behavior and solving life's headaches Dealing with depression resulting from grief and relationship issues Cutting through the hype of alternative treatments for depression Moving beyond depression: Avoiding relapses and pursuing a happy life Top Ten lists on getting rid of a your bad mood and helping your kids and other family members out of depression So, whatever your level of depression – whether you suffer from occasional bouts or you find yourself seriously debilitated by depression – Depression For Dummies can give you the insight and tools you need to once again find enjoyment and happiness in life. All it takes is one step.

Nervous System Drug Delivery

Nervous System Drug Delivery
Author : Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
Publisher : Academic Press
Release Date : 2019-06-25
Category : Medical
Total pages :556
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Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry

Translational Regenerative Medicine

Translational Regenerative Medicine
Author : Anthony Atala,Julie Allickson
Publisher : Academic Press
Release Date : 2014-12-01
Category : Science
Total pages :606
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Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Evidence-based Psychotherapy

Evidence-based Psychotherapy
Author : Carol D. Goodheart,Alan E. Kazdin,Robert J. Sternberg
Publisher : Amer Psychological Assn
Release Date : 2006
Category : Psychology
Total pages :295
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The adoption of evidence-based practice (EBP) has powerful ramifications for the future of psychotherapy. As the EBP movement spreads throughout healthcare, with its associated demands for demonstrable results, cost monitoring and accountability, mental health professionals are not in agreement on the best treatments and their bases or how to weight the factors that contribute to good outcomes. ""Evidence-Based Psychotherapy: Where Practice and Research Meet"" engages the voices of a broad range of clinical researchers, practitioners, educators, and public policy advocates in a comprehensive discussion of the spectrum of issues and arguments in the current debate about EBP. Acknowledging differences in the fundamental purposes of research and practice in psychology, a trio of distinguished editors (Carol D. Goodheart, Alan E. Kazdin, and Robert J. Sternberg) present a range of viewpoints on the role and nature of EBP from leading figures in clinical practice and research. Their intent is to instigate a dialogue among mental health professionals. To this end, the book offers distinctive perspectives, seeks common ground, and reveals legitimate differences, unanswered questions, and promising avenues for improving psychotherapy. The chapter authors examine the evolution, politics, treatment approaches and implications of EBP in psychotherapy. In their cogent introduction and notes between the sections, the editors tie together the book's themes, discuss their implications, and present conclusions. The final chapter lays out a series of cautions regarding EBP in psychotherapy tied to the themes arising in the book.

Encyclopedia of Molecular Mechanisms of Disease

Encyclopedia of Molecular Mechanisms of Disease
Author : Florian Lang
Publisher : Springer Science & Business Media
Release Date : 2009-03-19
Category : Science
Total pages :2268
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This comprehensive encyclopedia supplies the reader with concise information on the molecular pathophysiology of disease. Entries include defined diseases (such as Parkinson's disease) as well as pathophysiological entities (such as tremor). The 1,200 essays are brilliantly structured to allow rapid retrieval of the desired information. For more detailed reading, each entry is followed by up to five references. Individual entries are written by leading experts in the respective area of research to ensure state-of-the-art descriptions of the mechanisms involved. It is an invaluable companion for clinicians and scientists in all medical disciplines.

The Lobotomist

The Lobotomist
Author : Jack El-Hai
Publisher : John Wiley & Sons
Release Date : 2007-02-09
Category : Science
Total pages :372
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The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the twentieth century. Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Drawing on Freeman’s documents and interviews with Freeman's family, Jack El-Hai takes a penetrating look at the life and work of this complex scientific genius. The Lobotomist explores one of the darkest chapters of American medicine: the desperate attempt to treat the hundreds of thousands of psychiatric patients in need of help during the middle decades of the twentieth century. Into this crisis stepped Walter Freeman, M.D., who saw a solution in lobotomy, a brain operation intended to reduce the severity of psychotic symptoms. Although many patients did not benefit from the thousands of lobotomies Freeman performed, others believed their lobotomies changed them for the better. Drawing on a rich collection of documents Freeman left behind and interviews with Freeman's family, Jack El-Hai takes a penetrating look into the life of this complex scientific genius and traces the physician's fascinating life and work.