April 13, 2021

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Nitric Oxide

Nitric Oxide
Author : Louis J. Ignarro
Publisher : Academic Press
Release Date : 2000-09-13
Category : Science
Total pages :1017
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Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense

Experimental and Analytical Study of Nitric Oxide Formation During Combustion of Propane in a Jet-stirred Combustor

Experimental and Analytical Study of Nitric Oxide Formation During Combustion of Propane in a Jet-stirred Combustor
Author : N. T. Wakelyn
Publisher : Unknown
Release Date : 1978
Category : Combustion
Total pages :23
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The Effect of Nitric Oxide on the Radiosensitivity of Bacteria

The Effect of Nitric Oxide on the Radiosensitivity of Bacteria
Author : P. Howard-Flanders
Publisher : Unknown
Release Date : 1957
Category : Nitric oxide
Total pages :7
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Solubility of Xenon and Nitric Oxide in Various Solvents

Solubility of Xenon and Nitric Oxide in Various Solvents
Author : R. A. Penneman
Publisher : Unknown
Release Date : 1945
Category : Nitric oxide
Total pages :3
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Evaluation of a Nitric-oxide-compensated Carbon Monoxide Fire Sensor

Evaluation of a Nitric-oxide-compensated Carbon Monoxide Fire Sensor
Author : Charles D. Litton
Publisher : Unknown
Release Date : 1992
Category : Fire detectors
Total pages :10
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Upper Atmosphere O-atom Densities by Wind Tunnel Simulation of Nitric Oxide Releases

Upper Atmosphere O-atom Densities by Wind Tunnel Simulation of Nitric Oxide Releases
Author : D. Golomb
Publisher : Unknown
Release Date : 1967
Category : Nitric oxide
Total pages :4
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Decomposition of Nitric Oxide in a Hot Nitrogen Stream to Synthesize Air for Hypersonic-wind-tunnel Combustion Testing

Decomposition of Nitric Oxide in a Hot Nitrogen Stream to Synthesize Air for Hypersonic-wind-tunnel Combustion Testing
Author : John F. Zumdieck,Steven A. Zlatarich
Publisher : Unknown
Release Date : 1974
Category : Air
Total pages :27
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Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders

Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders
Author : Lucia Morbidelli,Benjamin Bonavida
Publisher : Academic Press
Release Date : 2019-02-09
Category : Medical
Total pages :372
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Therapeutic Application of Nitric Oxide in Cancer and Inflammatory Disorders presents updated reviews on the chemistry, signaling, pre-clinical and clinical activities on the role of nitric oxide donors/inhibitors used alone and in combination with other therapeutic agents for the treatment of a variety of diseases. This book examines various studies related to the application of novel therapeutic NO (donors/inhibitors) compounds in the treatment of various cancers. These studies have been shown to exert significant therapeutic activities against various cancers and various inflammatory diseases such as rheumatoid arthritis, Crohn’s disease, allergies, and asthma, where no current effective therapies exist. Pathologies based on functional and structural vascular alterations are also taken into consideration. Edited and written by internationally renowned experts in the field of novel therapeutics for cancer, this book is a valuable source for cancer researchers, medical scientists, clinicians, clinical pharmacologists, and graduate students. Provides readers with a clear overview of the recent findings and references as well as summaries, significant molecular pathways, and conclusions Discusses new ideas proposed and makes suggestions for further investigations that will advance the field Presents introductory and summary information on the contributions of the field, all the findings of the studies discussed, and projects future goals for research

Nitric Oxide Donors

Nitric Oxide Donors
Author : Amedea Seabra
Publisher : Academic Press
Release Date : 2017-03-17
Category : Medical
Total pages :364
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Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. Provides background information about biology and chemistry of nitric oxide Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity Discusses the future of nitric oxide donors and their FDA approval

Nitric Oxide Synthase

Nitric Oxide Synthase
Author : Seyed Soheil Saeedi Saravi
Publisher : BoD – Books on Demand
Release Date : 2017-05-17
Category : Science
Total pages :248
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Nitric Oxide Synthase - Simple Enzyme-Complex Roles provides information on nitric oxide synthase, a biomolecule of key importance for the different biological systems, including central and peripheral nervous, cardiovascular, and reproductive systems. With recent links to the role of nitric oxide in the reactions that can impact cell signaling, and discoveries surrounding the complex role of nitric oxide synthase that have increased research attention across the fields of cell and molecular biology, physiology, pharmacology, toxicology, neuroscience, cardiology, urology, and endocrinology, this book tries to provide a comprehensive overview of biology/pathobiology of nitric oxide synthases and a perspective from possible therapeutic indication of the enzyme inhibitors.

Nitric Oxide

Nitric Oxide
Author : Alexander Mengel,Christian Lindermayr
Publisher : Humana
Release Date : 2019-04-13
Category : Science
Total pages :302
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This volume explores three main aspects of nitric oxide (NO) research: NO treatment and detection, NO modifications, and NO detoxification. The book also covers methods used to study human/animal and plant nitric oxide. The chapters are divided into three parts: part one looks at NO treatments using gaseous nitric oxide and detection using a NO-sensitive electrode, electron spin resonance, and fluorescence-based NO-sensor proteins. Part two talks about various techniques used to detect and identify NO-dependent modifications, such as biotin-switch assay and quantification of s-nitrosated proteins. Part three focuses on the study of s-nitrosothiol homeostasis and denitrosation activities. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and authoritative, Nitric Oxide: Methods and Protocols is a valuable resource for anyone interested in learning more about this evolving field.

Nitric Oxide and Infection

Nitric Oxide and Infection
Author : Ferric C. Fang
Publisher : Springer Science & Business Media
Release Date : 1999-07-31
Category : Medical
Total pages :517
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Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has established nitric oxide and related reactive nitrogen intermediates to be important molecular mediators of diverse physiologic processes such as control of vascular tone, regulation of the immune system, and microbial and tumor cell growth. This book contains chapters by the leading researchers in the field and examines the biology and biochemistry of nitric oxide and its role in a variety of specific infections ranging from sepsis, tuberculosis and malaria to viral myocarditis, influenza, and AIDS.

Nitrosation Reactions and the Chemistry of Nitric Oxide

Nitrosation Reactions and the Chemistry of Nitric Oxide
Author : D.L.H. Williams
Publisher : Elsevier
Release Date : 2004-12-16
Category : Science
Total pages :280
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Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990. * Provides an update on previously published literature on nitric oxide chemistry * Contains chapters on reagents for nitrosation, nitrosation at nitrogen, aliphatic and aromatic carbon, oxygen, sulfur and metal centres * Looks at hot research topics such as synthesis, properties and reactions of s-nitrosothiols