June 12, 2021

Download Ebook Free Non-Enzymatic Protein Modifications In Health, Disease And Ageing

Non-Enzymatic Protein Modifications in Health, Disease and Ageing

Non-Enzymatic Protein Modifications in Health, Disease and Ageing
Author : Izabela Sadowska-Bartosz,Grzegorz Bartosz
Publisher : Academic Press
Release Date : 2018-11-15
Category :
Total pages :252
GET BOOK

There is increased understanding of the fate of intracellular and extracellular proteins, including the many types of posttranslational modifications that proteins undergo. Among these modifications, non-enzymatic protein modifications play a special role. These are unavoidable products of side reactions of reactive metabolites, and often damage proteins and induce loss of function. Non-Enzymatic Protein Modifications in Health, Diseases and Ageing discusses each type of non-enzymatic protein, both introducing non-enzymatic protein modifications, and reviewing the state of the art, presenting updates and current trends. The book covers various aspects of the subject, including formation and removal of modified proteins, their roles in disease, preventative methods, and possible roles in cellular signalling. Finally, the book not only provides well-established facts, but also discusses current hypotheses and controversies. Provides the basic chemical knowledge necessary to understand non-enzymatic protein modifications, of particular use to researchers looking for an introduction to and overview of the field Combines a systematic chemical introduction to non-enzymatic protein modifications with a review of the state of the art Presents together, types of non-enzymatic protein usually reported and reviewed separately Considers current hypotheses and controversies alongside the facts

Investigative Ophthalmology & Visual Science

Investigative Ophthalmology & Visual Science
Author : Anonim
Publisher : Unknown
Release Date : 2009
Category : Ophthalmology
Total pages :129
GET BOOK

Molecular Basis and Emerging Strategies for Anti-aging Interventions

Molecular Basis and Emerging Strategies for Anti-aging Interventions
Author : Syed Ibrahim Rizvi,Ufuk Çakatay
Publisher : Springer
Release Date : 2018-11-02
Category : Medical
Total pages :386
GET BOOK

This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences.

Protein Metabolism and Homeostasis in Aging

Protein Metabolism and Homeostasis in Aging
Author : Nektarios Tavernarakis
Publisher : Springer Science & Business Media
Release Date : 2011-01-11
Category : Medical
Total pages :249
GET BOOK

Aging is loosely defined as the accumulation of changes in an organism over time. At the cellular level such changes are distinct and multidimensional: DNA replication ceases, cells stop dividing, they become senescent and eventually die. DNA metabolism and chromosomal maintenance, together with protein metabolism are critical in the aging process. The focus of this book is on the role of protein metabolism and homeostasis in aging. An overview is provided of the current knowledge in the area, including protein synthesis, accuracy and repair, post-translational modifications, degradation and turnover, and how they define and influence aging. The chapters mainly focus on well-characterised factors and pathways, but new areas are also presented, where associations with aging are just being elucidated by current experimental data. Protein turnover, the balance between protein synthesis and protein degradation are carefully maintained in healthy cells. Chapters 1 and 2 illustrate that aging cells are characterised by alterations in the rate, level and accuracy of protein synthesis compared to young ones, and that mRNA translation, essential for cell growth and survival, is controlled at multiple levels. The theory that growth and somatic maintenance are believed to be antagonistic processes is described in Chapter 3: inhibition of protein synthesis results in decreased rates of growth and development, but also confers an extension of lifespan, as shown for example by the effects of dietary restriction in various models organisms.

The Aging Kidney in Health and Disease

The Aging Kidney in Health and Disease
Author : Juan F. Macías-Núñez,J. Stewart Cameron,Dimitrios G. Oreopoulos
Publisher : Springer Science & Business Media
Release Date : 2007-11-24
Category : Medical
Total pages :553
GET BOOK

This volume will be a reliable source on the management of the elderly with renal disease. There is an ever-increasing proportion of the aging population affected by renal disease and hypertension, and physicians are faced with atypical clinical presentations of renal disease in the aged as compared to younger people. This volume combines the fields of nephrology and geriatrics and presents a multidisciplinary approach to the topic.

Lung Macrophages in Health and Disease

Lung Macrophages in Health and Disease
Author : Sandra Hodge
Publisher : Bentham Science Publishers
Release Date : 2009-09-12
Category : Lungs
Total pages :120
GET BOOK

"This Ebook is edited by Sandra Hodge, a recognized expert in the field of macrophage dysfunction in chronic lung disease. The book consists of 8 chapters which provide a full coverage of macrophage function in both healthy and chronically diseased lungs, "

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1990: Department of Education

Departments of Labor, Health and Human Services, Education, and Related Agencies Appropriations for 1990: Department of Education
Author : United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publisher : Unknown
Release Date : 1989
Category : United States
Total pages :129
GET BOOK

Proceedings of the National Academy of Sciences of the United States of America

Proceedings of the National Academy of Sciences of the United States of America
Author : National Academy of Sciences (U.S.)
Publisher : Unknown
Release Date : 1992
Category : Electronic journals
Total pages :129
GET BOOK

Neuroscience Letters

Neuroscience Letters
Author : Anonim
Publisher : Unknown
Release Date : 1997-03
Category : Neurology
Total pages :129
GET BOOK

Abstracts, 22nd Annual Meetings , March 13-31, 1993

Abstracts, 22nd Annual Meetings , March 13-31, 1993
Author : Anonim
Publisher : Unknown
Release Date : 1993
Category : Cytochemistry
Total pages :296
GET BOOK

Federation Proceedings

Federation Proceedings
Author : Federation of American Societies for Experimental Biology
Publisher : Unknown
Release Date : 1987-03
Category : Biology
Total pages :129
GET BOOK

Vols. for 1942- include proceedings of the American Physiological Society.

The Journal of Experimental Medicine

The Journal of Experimental Medicine
Author : Anonim
Publisher : Unknown
Release Date : 1987
Category : Electronic journals
Total pages :129
GET BOOK

South African Journal of Science

South African Journal of Science
Author : Anonim
Publisher : Unknown
Release Date : 2000
Category : Science
Total pages :129
GET BOOK

Molecular and Cellular Biology of Diabetes Mellitus: Complications of diabetes mellitus

Molecular and Cellular Biology of Diabetes Mellitus: Complications of diabetes mellitus
Author : Boris Draznin,Shlomo Melmed,Derek LeRoith
Publisher : Unknown
Release Date : 1989
Category : Diabetes
Total pages :168
GET BOOK

Toxicology Research Projects Directory

Toxicology Research Projects Directory
Author : Anonim
Publisher : Unknown
Release Date : 1977
Category : Research
Total pages :129
GET BOOK

An indexed directory of current research project abstracts in toxicology and related fields.