December 2, 2020

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Novel Psychoactive Substances

Novel Psychoactive Substances
Author : Paul Dargan,David Wood
Publisher : Academic Press
Release Date : 2013-08-06
Category : Medical
Total pages :440
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Novel Psychoactive Substances: Classification, Pharmacology and Toxicology provides readers with background on the classification, detection, supply and availability of novel psychoactive substances, otherwise known as "legal highs." This book also covers individual classes of novel psychoactive substances that have recently emerged onto the recreational drug scene and provides an overview of the pharmacology of the substance followed by a discussion of the acute and chronic harm or toxicity associated with the substance. Written by international experts in the field, this multi-authored book is a valuable reference for scientists, clinicians, academics, and regulatory and law enforcement professionals. Includes chapters written by international experts in the field. Provides a comprehensive look at the classification, detection, availability and supply of novel psychoactive substances, in addition to the pharmacology and toxicology associated with the substance. Offers a single source for all interested parties working in this area, including scientists, academics, clinicians, law enforcement and regulatory agencies. Provides a full treatment of novel psychoactive substances that have recently emerged onto the recreational drug scene including mephedrone and the synthetic cannabinoid receptors in ‘spice’ / ‘K2’.

Novel Psychoactive Drugs

Novel Psychoactive Drugs
Author : Liana Fattore,Aviv Weinstein
Publisher : Frontiers Media SA
Release Date : 2019-06-05
Category :
Total pages :196
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An increasing number of novel psychoactive drugs are currently available and sold as 'legal highs' or 'research chemicals'. These New Psychoactive Substances (NPS) constitute a broad range of hundreds of natural and synthetic drugs, including synthetic cannabinoids, synthetic cathinones, synthetic opioids and other classes, which use has resulted in a significantly growing number of intoxication and mortality, as reported by emergency and poison centres from all over the world. Definition of “NPS” includes any substance that has recently become available and has been designed purposely to replace illegal drugs, although not necessarily of new synthesis. Use of NPS is dramatically increased in the last decade and represents a serious risk for the public health. Their ever-evolving chemical structure, the possibility to distribute in real time through the Internet and social networks information about their use and effects have dramatically challenged public health and drug policies internationally. NPS recently attracted great attention, but most are still unregulated and proposed online as legal alternatives to traditional illicit drugs. Unfortunately, this area is still poorly investigated and very limited information are available so far on their nature and potential risks. The phenomenon of NPS requires multi-national and multi-disciplinary collaborations to improve our knowledge on this changing drug market, to share information and define good practices at a global level. Political and educational efforts are indispensable to regulate this mutable scenario and to inform the public about health consequences of NPS use. Clinicians and emergency staff should be aware that NPS may cause severe health consequences and unexpected adverse effects, and be informed on how to recognized and treat specific intoxication cases. Considering the widespread use of NPS and paucity of information about their toxicology and pharmacology, this Research Topic will be useful to understand the new trends in the scenario of drug use, abuse and addiction to inform professionals and general public about the health problems caused by NPS and to help drug-control policies to adopt suitable control measures.

Handbook of Novel Psychoactive Substances

Handbook of Novel Psychoactive Substances
Author : Ornella Corazza,Andres Roman-Urrestarazu
Publisher : Routledge
Release Date : 2018-10-10
Category : Psychology
Total pages :386
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Handbook of Novel Psychoactive Substances (NPS) provides a comprehensive overview of the challenges that clinicians face when dealing with NPS and discusses how the profile of patients and their socio-demographic characteristics frame the serious public health concern that NPS pose. It presents various clinical cases, as well as detailed accounts of symptoms, psychopathology, toxicity, and overall clinical management that NPS require. This handbook brings together a unique collection of chapters written by leading experts in the field, who have felt the need to share their knowledge and experience to improve the clinical practice on NPS and the wellbeing of their patients.

Novel Psychoactive Substances

Novel Psychoactive Substances
Author : Ornella Corazza,Andres Roman-Urrestarazu
Publisher : Springer
Release Date : 2017-08-09
Category : Business & Economics
Total pages :178
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In light of the recent emergence of Novel Psychoactive Substances (NPS) on a global scale, this book provides a timely analysis of the social and economic impact of the NPS phenomenon, and of the global policy and regulatory responses to it. It presents the first comprehensive overview of the international regulation, policy and market structure of the NPS phenomenon, offering a guide to inform legislative discussions and demonstrating from a comparative perspective the different approaches used to address the rise of NPS to date. It covers topics such as organized crime, drug markets, clinical evidence on NPS, and different regulatory approaches also in less explored settings such as prisons and sport environments. Overall, this highly informative and well-structured repository of different experiences with NPS policy, law and regulation offers an essential primary source of evidence for anyone interested in the area of drug and NPS policy, health economics and p ublic health.

Club Drugs and Novel Psychoactive Substances

Club Drugs and Novel Psychoactive Substances
Author : Owen Bowden-Jones,Dima Abdulrahim
Publisher : Cambridge University Press
Release Date : 2020-10-08
Category : Medical
Total pages :150
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Emerging illicit drugs pose a significant clinical challenge. This handbook offers an engaging, concise guide to managing these challenges.

Recent Changes in Drug Abuse Scenario The Novel Psychoactive Substances (NPS) Phenomenon

Recent Changes in Drug Abuse Scenario The Novel Psychoactive Substances (NPS) Phenomenon
Author : Fabrizio Schifano
Publisher : MDPI
Release Date : 2019-01-15
Category :
Total pages :198
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This book is a printed edition of the Special Issue "Recent Changes in Drug Abuse Scenario: The Novel Psychoactive Substances (NPS) Phenomenon" that was published in Brain Sciences

Novel Psychoactive Substances

Novel Psychoactive Substances
Author : Joseph Ritchie
Publisher : Unknown
Release Date : 2017
Category :
Total pages :129
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Neuropharmacology of New Psychoactive Substances (NPS)

Neuropharmacology of New Psychoactive Substances (NPS)
Author : Michael H. Baumann,Richard A. Glennon,Jenny L. Wiley
Publisher : Springer
Release Date : 2017-04-13
Category : Medical
Total pages :380
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Designer drugs, or new psychoactive substances (NPS), are synthetic chemicals that mimic the effects of classic drugs of abuse. There has been an alarming worldwide increase in the abuse of NPS in recent years. NPS are cheap, easy to obtain, and often legally available. In this volume, leading experts summarize the latest studies regarding the molecular mechanisms of action, behavioral effects, and adverse consequences of popular NPS. Specific chapters clarify the differences between various types of NPS, namely: stimulants, cannabinoids and hallucinogens. Thus, this volume broadens our understanding of NPS and provides insight into the rapidly evolving “new drug” phenomenon.

Novel Psychoactive Substances

Novel Psychoactive Substances
Author : Christophe Soussan
Publisher : Unknown
Release Date : 2018
Category :
Total pages :91
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Synthetic Cathinones

Synthetic Cathinones
Author : Jolanta B. Zawilska
Publisher : Springer
Release Date : 2018-04-16
Category : Medical
Total pages :207
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Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Mental Illness Reinvented: The Impact of Novel Psychoactive Substances

Mental Illness Reinvented: The Impact of Novel Psychoactive Substances
Author : Filipa Viegas
Publisher : Unknown
Release Date : 2017
Category :
Total pages :129
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Objectives:To conduct a non-systematic literature review on novel psychoactive substances use and their potential impacts in mental health.Background:With the explosion of designer drug industry, there has been a major increase in the number of new drugs of abuse over the past decade.These substances, designated as u201cnovel psychoactive substancesu201d (NPS), comprise a vast range of compounds, and their psychoactive effects depend on their u201cparent drugu201d and its actions on cognitive processes, mood, and behaviour.The aim of this work is to explore the impact of NPS use in mental health.Materials and Methods:We proceed to a non-systematic literature review, throughout electronic databases using combinations of terms related to novel psychoactive substance and mental healh.Results and Conclusions:NPS represent a new chapter in substance use and addition areas and represents a complex public health problem, raising issues in what concern legal regulations and on the consequences of their use.Literature suggest a wide range of adverse effects, from transient depressive mood alterations, suicide ideation to drug-induced psychotic states. Among the population with severe mental illness, literature suggests that they seem more likely to use NPS and that this use could modify clinical features of the illness, but the evidence is still poor. More evidence is needed to establish the impact and connexion between NPS and mental illness, in terms of type of psychiatric symptoms, course of illness and short- and long-term impact of their use.

The Essential Guide to Psychoactive Drugs in Canada, Second Edition

The Essential Guide to Psychoactive Drugs in Canada, Second Edition
Author : Rick Csiernik
Publisher : Canadian Scholars’ Press
Release Date : 2019-11-19
Category : Medical
Total pages :419
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The second edition of the formerly titled Just Say Know: A Counsellor’s Guide to Psychoactive Drugs, this indispensable counselling resource provides a practical understanding of psychoactive drug pharmacology and physiology. Rick Csiernik unpacks the risks and therapeutic applications of the most commonly used and misused drug families, including depressants, stimulants, hallucinogens, and psychotherapeutics. This new edition features a wide range of updated research and content addressing the recent rise of opioid, fentanyl, cannabis, novel psychoactive substances, and antipsychotic medication use, as well as the impacts of drug use on sleep and mental health. Two new appendixes are featured summarizing the effects of drugs on pregnancy and interactions drugs may have with certain brain chemicals. The Essential Guide to Psychoactive Drugs in Canada is the perfect addition to any addiction or mental health-related course. User-friendly and highly readable, this resource serves as a guide for service providers to deliver evidence-based care. This text is crucial for counsellors, therapists, instructors, and students looking to acquire an in-depth practical understanding of drug use, medication, and addiction in disciplines such as social work, sociology, pharmacology, health studies, nursing, psychology, and addiction studies.

11 - E-DESIGNER DRUGS - NOVEL PSYCHOACTIVE SUBSTANCES IN LIQUIDS FOR E-CIGARETTES

11 - E-DESIGNER DRUGS - NOVEL PSYCHOACTIVE SUBSTANCES IN LIQUIDS FOR E-CIGARETTES
Author : Milena Majchrzak
Publisher : Unknown
Release Date : 2017
Category :
Total pages :129
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Introduction: Classic e-liquids for vaporizers and e-cigarettes contain nicotine in a propylene glycol solution. A new phenomenon on the drug market is the intentional addition of novel psychoactive substances to liquids for e-cigarettes.Objectives: Our objective was drawing attention to a new health problem, so called drug vaping.Methods: Analysis of two cases from the expert practice of the authors, one with survival of the victim, and one lethal.Results: In the first case, the father of a 17-year-old girl has provided to the toxicological analysis e-cigarettes with the content of viscous liquid that she used. After burning, she began to behave strangely and experienced epileptic seizures. In the analyzed sample from evidence material, the presence of a substance characterized by a pseudomolecular ion with a value of m/z = 375 and the retention time corresponding to the furanylfentanyl (an opioid analgesic, also known as Fu-F) pattern was demonstrated. In the second case, an adult man was supposed to smoke an e-cigarette, to which he added cannabinols, before his death. In the analyzed blood sample the presence of a substance characterized by a pseudomolecular ion with a value of m/z = 378 and a retention time consistent with the standard of 5F-ADB (an indazole-based synthetic cannabinoid, also known as 5F-MDMB-PINACA) was demonstrated. Additionally, in the analyzed urine sample two metabolites of 5F-ADB have been found.Conclusions: The use of electronic vaping devices for recreational drug and new psychoactive substance (NPS) administration is a real new danger for health and even live of abusers.

Young People's Perceptions of Novel Psychoactive Substances

Young People's Perceptions of Novel Psychoactive Substances
Author : Jodie Freeman
Publisher : Unknown
Release Date : 2018
Category :
Total pages :129
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Addictive Substances and Neurological Disease

Addictive Substances and Neurological Disease
Author : Ronald Ross Watson,Sherma Zibadi
Publisher : Academic Press
Release Date : 2017-02-18
Category : Medical
Total pages :414
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Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. Integrates current research on the actions of addictive substances in neurological disease Includes functional foods, such as caffeine beverages, that have habituating effects on the brain Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances