January 25, 2021

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Osteoimmunology

Osteoimmunology
Author : Joseph Lorenzo,Mark Horowitz,Yongwon Choi,Hiroshi Takayanagi
Publisher : Academic Press
Release Date : 2010-09-24
Category : Medical
Total pages :470
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Bone and the immune system are both complex tissues, which, respectively, regulate the skeleton and the body's responses to invading pathogens. Critical interactions between these two organ systems frequently occur, particularly in the development of immune cells in the bone marrow and for the function of bone cells in health and disease. This book provides a detailed overview of the many ways that bone and immune cells interact. The goal is to provide basic and clinical scientists with a better understanding of the role that the immune system and bone play in the development and function of each other so that advances in both fields will be facilitated. The focus of the book will be both on basic pathways and translational science, which will apply basic knowledge to clinical diseases. Chapter content will range from basic descriptions of the various cell systems and their development to the signals that cause them to interact during normal physiology and disease. This is a rapidly developing area that is of interest to a wide spectrum of researchers, students, and fellows in immunology, rheumatology, hematology, and bone biology--all of whom need to develop a more complete understanding of their previously separate disciplines and the mechanisms by which they interact. Presents a comprehensive, translational source for all aspects of osteoimmunology in one reference work Experts in bone biology and immunology (from all areas of academic and medical research) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches. Clear presentations by bone biologists of the cellular and molecular mechanisms underlying bone cell development leading to bone and immunological diseases such as Lupus Clear presentations by immunologists of how immune cells develop and how the immune system plays a role in bone diseases like osteoporosis and arthritis

Principles of Osteoimmunology

Principles of Osteoimmunology
Author : Peter Pietschmann
Publisher : Springer
Release Date : 2016-08-18
Category : Medical
Total pages :328
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This fully updated and extended second edition provides a comprehensive overview on the basic concepts of the rapidly developing field of osteoimmunology and also offers in-depth insights into the molecular mechanisms of bone diseases. Clinical data is presented and put into context with the latest research findings. This second edition in addition discusses the latest topics in transplantation immunology. The book addresses scientists and physicians working in immunology, pathophysiology and osteology.

Osteoimmunology

Osteoimmunology
Author : Yongwon Choi
Publisher : Springer Science & Business Media
Release Date : 2012-12-09
Category : Medical
Total pages :138
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This is the second edition of this proceedings. Contributors include leading names in the field of research, addressing mutiple topics, which were covered at the last Osteoimmunology conference.

Advances in Osteoimmunology

Advances in Osteoimmunology
Author : Claudine Blin-Wakkach,Teun J. de Vries
Publisher : Frontiers Media SA
Release Date : 2020-01-21
Category :
Total pages :129
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Updates on Osteoimmunology: What’s New on the Crosstalk Between Bone and Immune Cells

Updates on Osteoimmunology: What’s New on the Crosstalk Between Bone and Immune Cells
Author : Giacomina Brunetti,Patrizia D’Amelio,Giorgio Mori,Maria Felicia Faienza
Publisher : Frontiers Media SA
Release Date : 2020-03-24
Category :
Total pages :129
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Advances in Molecular Oncology

Advances in Molecular Oncology
Author : Fabrizio d'Adda di Fagagna,Susanna Chiocca,Fraser McBlane,Ugo Cavallaro
Publisher : Springer
Release Date : 2007-07-12
Category : Medical
Total pages :276
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Proceedings of the 2nd Annual IFOM-IEO Meeting on Cancer. This is a new meeting, it has about 200 attendees from Australia, Austria, Belgium, Brazil, Canada, England, France, Germany, Greece, Ireland, Italy, Japan, Netherlands, Spain, Sweden, Switzerland, and the USA. The 2nd IFOM-IEO international meeting on cancer will provide a forum in which the world’s leading cancer researchers and young scientists will discuss the latest advances in molecular oncology. The impact of recent breakthroughs in basic research and of emerging technologies on molecular medicine in cancer will be highlighted.

Osteoimmunology and Cancer - Clinical Implications

Osteoimmunology and Cancer - Clinical Implications
Author : Evangelos Terpos
Publisher : Unknown
Release Date : 2011
Category : Medicine
Total pages :129
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Osteoimmunology and Cancer - Clinical Implications.

Innate Immunity in the Context of Osteoimmunology

Innate Immunity in the Context of Osteoimmunology
Author : Cristina Sobacchi,Anita Ignatius
Publisher : Frontiers Media SA
Release Date : 2020-05-28
Category :
Total pages :129
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Acknowledgments We acknowledge the initiation and support of this Research Topic by the International Union of Immunological Societies (IUIS). We hereby state publicly that the IUIS has had no editorial input in articles included in this Research Topic, thus ensuring that all aspects of this Research Topic are evaluated objectively, unbiased by any specific policy or opinion of the IUIS.

Osteoimmunopathology

Osteoimmunopathology
Author : Francesco Chiappelli
Publisher : Springer Science & Business Media
Release Date : 2011-05-30
Category : Medical
Total pages :137
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Osteoimmunology pertains to the study of the relationship between the bones, particularly the bone marrow, and the immune system. This monograph pursues the best available evidence, by means of research synthesis, for the characterization of the physiological relevance and pathological implications of the inter-connectedness between the skeletal and the immune system. Research will be discussed that highlights the associated role of the circulatory, nervous and endocrine systems, as well as proteomic and genomic pathways and signatures. Emphasis is given that domain of medicine that relates to the oral cavity, its diseases and their systemic sequelae. This monograph arises from observations that have suggested that the skeletal system and the immune system are intimately intertwined. Chronic inflammatory reactions subsequent to an excessive immune reaction can damage the bones, as in rheumatoid arthritis (RA), osteoporosis, patients seropositive for the human immunodeficiency virus (HIV)-1 and with signs and symptoms of the acquired immune deficiency syndrome (AIDS), and bone cancer. Bones – in particular the bone marrow – are one of the primary locations in which cells of the immune system mature. In brief, this monograph begins to answer a range of questions, such as, what is osteoimmunology all about?, does the immune system and its components affect bone development?, how do stress hormones impact upon the pathophysiology of bone-immune interactions?, can the scientific process of research synthesis, obtain the best available evidence for treatment of diseases involving the bone-immune entity (i.e., osteo immunopathologies) means of evidence-based clinical decision-making directed at the treatment of osteoimmune pathologies?

Rheumatology E-Book

Rheumatology E-Book
Author : Marc C. Hochberg,Alan J. Silman,Josef S. Smolen,Michael E. Weinblatt,Michael H. Weisman
Publisher : Elsevier Health Sciences
Release Date : 2014-06-16
Category : Medical
Total pages :2112
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Stay current in the ever-changing discipline of rheumatology with clear, reliable guidance from Hochberg’s Rheumatology, one of the most respected and trusted sources in the field. Designed to meet the needs of the practicing clinician, this medical reference book provides extensive, authoritative coverage of rheumatic diseases from basic scientific principles to practical points of clinical management in a lucid, logical, user-friendly manner. Track disease progression and treat patients more effectively with the information on genetic findings, imaging outcomes, cell and biologic therapies, rheumatoid arthritis, and SLE. Incorporate recent findings about pathogenesis of disease; imaging outcomes for specific diseases like RA, osteoarthritis, and spondyloarthropathies; cell and biologic therapies; and other timely topics. Remain up to date on the latest information in rheumatology through 13 brand-new chapters covering biomedical and translation science, disease and outcome assessment, new imaging modalities, early emerging disease, clinical therapeutics, patient management, and rehabilitation. Take advantage of expanded coverage of small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. Focus on the core knowledge needed for successful results with each chapter co-authored by an internationally-renowned specialist in the field. Easily find the information you need thanks to a consistent, user-friendly format with templated content and large-scale images.

Topics in Osteoporosis

Topics in Osteoporosis
Author : Margarita Valdés-Flores
Publisher : BoD – Books on Demand
Release Date : 2013-05-15
Category : Medical
Total pages :290
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Osteoporosis affects the osteo-articular system. However, there are hormonal, kidney related, gastrointestinal and neuromuscular factors among other, that can be involved in the etiopathogenesis of the disease. In the other hand, for osteoporosis prevention there are many lifestyle conditions that are very important, as dietary habits, physical activity, drugs and caffeine intake, smoking, associated diseases, etc. Based on the above, treatment and prevention of osteoporosis have to be addressed in a multidisciplinary and integral approach. The knowledge about bone metabolism and the related disorders represents an extensive field that is currently increasing through many investigations conducted in the world. The purpose of this book is to show several reviews and original investigations related with osteoporosis.

The Immune Response to Implanted Materials and Devices

The Immune Response to Implanted Materials and Devices
Author : Bruna Corradetti
Publisher : Springer
Release Date : 2016-11-30
Category : Technology & Engineering
Total pages :241
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This book provides a comprehensive overview of the cascade of events activated in the body following the implant of biomaterials and devices. It is one of the first books to shed light on the role of the host immune response on therapeutic efficacy, and reviews the state-of-the-art for both basic science and medical applications. The text examines advantages and disadvantages of the use of synthetic versus natural biomaterials. Particular emphasis is placed on the role of biomimicry in the development of smart strategies able to modulate infiltrating immune cells, thus reducing side effects (such as acute and chronic inflammation, fibrosis and/or implant rejection) and improving the therapeutic outcome (healing, tissue restoration). Current cutting-edge approaches in tissue engineering, regenerative medicine, and nanomedicine offer the latest insights into the role immunomodulation in improving tolerance during tissue transplant in the treatment of orthopaedic, pancreatic, and hepatic diseases. "Immune Response to Implanted Materials and Devices" is intended for an audience of graduate students and professional researchers in both academia and industry interested in the development of smart strategies, which are able to exploit the self-healing properties of the body and achieve functional tissue restoration.

Basic and Applied Bone Biology

Basic and Applied Bone Biology
Author : David B. Burr,Matthew R. Allen
Publisher : Academic Press
Release Date : 2013-06-11
Category : Medical
Total pages :390
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This book provides an overview of skeletal biology from the molecular level to the organ level, including cellular control, interaction and response; adaptive responses to various external stimuli; the interaction of the skeletal system with other metabolic processes in the body; and the effect of various disease processes on the skeleton. The book also includes chapters that address how the skeleton can be evaluated through the use of various imaging technologies, biomechanical testing, histomorphometric analysis, and the use of genetically modified animal models. Presents an in-depth overview of skeletal biology from the molecular to the organ level Offers "refresher" level content for clinicians or researchers outside their areas of expertise Boasts editors and many chapter authors from Indiana and Purdue Universities, two of the broadest and deepest programs in skeletal biology in the US; other chapter authors include clinician scientists from pharmaceutical companies that apply the basics of bone biology

Osteosarcoma

Osteosarcoma
Author : Kanya Honoki,Kurt Weiss
Publisher : BoD – Books on Demand
Release Date : 2017-04-26
Category : Medical
Total pages :254
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Osteosarcoma is the most common malignant bone tumor and mainly affects children, adolescents, and young adults. Osteosarcoma shows significant genetic instability, resulting in very complex biology with multifaceted cellular and molecular mechanisms and behavior. Although clinical outcomes, both prognostic and functional, of osteosarcoma dramatically improved in the 1980s, the prognoses of the patients with relapsed and/or metastatic disease remained very poor in spite of our continuous efforts to overcome this difficulty. This book aims to delve into the current advances of basic and clinical sciences in osteosarcoma that are guiding the future directions of its research and clinical practice. The knowledge presented here will lead to further inspiration, ideas, and novel insights into the field of osteosarcoma research. Hopefully, this work will foster improvement of the prognosis for patients suffering from the disease.

Advances in Immunology

Advances in Immunology
Author : Frederick W. Alt
Publisher : Academic Press
Release Date : 2007-10-01
Category : Medical
Total pages :282
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Advances in Immunology, a long established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for future research.