June 19, 2021

Download Ebook Free Overview Of Radiation And Non-radiation Modalities For Cancer Treatment

Overview of Radiation and Non-Radiation Modalities for Cancer Treatment

Overview of Radiation and Non-Radiation Modalities for Cancer Treatment
Author : Oiendrila Bhowmik Debnath
Publisher : Academic Press
Release Date : 2020-08
Category : Technology & Engineering
Total pages :550
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Overview of Radiation and Non-radiation Modalities for Cancer Treatment: A Biomedical Engineering Perspective is a comprehensive reference on the different modalities and therapeutic instruments of cancer treatment from a medical physics perspective. The book is divided into 3 main sections; radiation therapy, non-radiation therapy and combination therapy. The focus of this book is on the mechanisms which underpin engineering and medical physics. This sets the book apart from other texts on this topic which primarily focus on biology. The fundamental physics behind the techniques used in cancer diagnosis or therapy modalities is also introduced in this text. This resource provides readers with the latest technologies used in clinics for cancer diagnosis and therapy, and their advantages and disadvantages. Gives an overview on the latest technology Covers the basic principles of each technology Explores the latest research and challenges in each modality

Lung Cancer

Lung Cancer
Author : Karen L. Reckamp
Publisher : Springer
Release Date : 2016-08-17
Category : Medical
Total pages :322
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This book describes the molecular mechanisms of lung cancer development and progression that determine therapeutic interventions in the era of genomics, when the rapid evolution in lung cancer diagnosis and treatment necessitates critical review of new results to integrate advances into practice. The text opens with background and emerging information regarding the molecular biology of lung cancer pathogenesis. Updated results regarding lung cancer prevention and screening are discussed, followed by chapters on diagnostic techniques and pathological evaluation. This leads on to a detailed presentation of treatment modalities, from surgery and radiation therapy to standard chemotherapy and targeted agents. The coverage includes resistance to therapy and the emergence of immunotherapy for lung cancer; in addition, the current evidence in respect of small cell lung cancer is summarized. The book presents insights from experts across disciplines to emphasize the importance of collaborative care. Advances in our understanding of issues in geriatric oncology and palliative care complete the comprehensive discussion of lung cancer.

Perez & Brady's Principles and Practice of Radiation Oncology

Perez & Brady's Principles and Practice of Radiation Oncology
Author : Edward C. Halperin,Luther W. Brady,Carlos A. Perez,David E. Wazer
Publisher : Lippincott Williams & Wilkins
Release Date : 2013-06-05
Category : Medical
Total pages :1936
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Inside the Sixth Edition of this now-classic reference, you will discover encyclopedic coverage of topics ranging from basic science to sophisticated computer-based radiation therapy treatment planning and supportive care. The book’s comprehensive scope and abundantly illustrated format provide you with better understanding of the natural history of cancer, the physical methods of radiation application, the effects of radiation on normal tissues, and the most judicious ways in which you can employ radiation therapy in patient care. Traditionally available as a printed textbook, now it comes with a completely revamped digital experience, powered by Inkling! NEW to the Sixth Edition... • Site-specific chapters include relevant background information on each tumor—including epidemiology, pathology, diagnostic work-up, prognostic factors, treatment techniques, applications of surgery and chemotherapy, end results, and more. • Over 1,400 full-color illustrations highlight key concepts in tumor pathogenesis, diagnosis, and targeted radiation therapy. • Increased emphasis on new approaches and technologies improve your understanding of three-dimensional treatment planning, intensity-modulated radiotherapy, combined modality therapy, and particle therapy. • Greater emphasis on palliative and supportive care reflects the role of radiation treatment in non-curative roles. • New editors and contributors let you benefit from their decades of experience. • Digital version includes the complete text, index-based search, note sharing, regular content updates integrated into the text, and much more.

Squamous Cell Head and Neck Cancer

Squamous Cell Head and Neck Cancer
Author : David J. Adelstein
Publisher : Springer Science & Business Media
Release Date : 2007-11-06
Category : Medical
Total pages :358
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Leading expert physicians and investigators from around the world review the state-of-the-art in the management of squamous cell head and neck cancer, with emphasis on coordinating different treatment modalities. The authors address several surgical issues, including laser-based surgery, larynx preservation approaches, salvage surgery, and neck management after non-operative treatment. They also discuss definitive radiation for larynx cancer, brachytherapy, altered fractionation radiation, intensity modulated radiation therapy, and the importance of tumor hypoxia, as well as the role of chemotherapy in sequential, concurrent, and adjuvant multi-modality treatment schedules. Other topics of special interest include targeted and gene therapies, multimodality management of nasopharyngeal cancer, chemoprevention, toxicity modification, quality of life outcomes, symptom palliation, and epidemiology.

Anticancer Research

Anticancer Research
Author : Anonim
Publisher : Unknown
Release Date : 2008
Category : Cancer
Total pages :129
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Radiation Therapy Planning, An Issue of PET Clinics - E-Book

Radiation Therapy Planning, An Issue of PET Clinics - E-Book
Author : Sushil Beriwal
Publisher : Elsevier Health Sciences
Release Date : 2011-06-29
Category : Medical
Total pages :140
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PET imaging has become an essential part of radiation therapy for cancer patients. Leading off the issue are articles on clinical applications and technical aspects. Following those are reviews of the use of PET in the treatment for lung cancer, gynecologic malignancies, GI and pancreatic tumors, and brain tumors, lymphoma, and head and neck malignancies. The final article addresses advances in hybrid imaging in planning of radiation therapy.

Radiotherapy in Cancer Care

Radiotherapy in Cancer Care
Author : International Atomic Energy Agency,Eduardo Zubizarreta
Publisher : Unknown
Release Date : 2017-11-28
Category : Medical
Total pages :544
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Cancer treatment is complex and calls for a diverse set of services. Radiation therapy is recognized as an essential tool in the cure and palliation of cancer. Currently, access to radiation treatment is limited in many countries and non-existent in some. This lack of radiation therapy resources exacerbates the burden of disease and underscores the continuing health care disparity among States. Closing this gap represents an essential measure in addressing this global health equity problem. This publication presents a comprehensive overview of the major topics and issues to be taken into consideration when planning a strategy to address this problem, in particular in low and middle income countries. With contributions from leaders in the field, it provides an introduction to the achievements and issues of radiation therapy as a cancer treatment modality around the world. Dedicated chapters focus on the new radiotherapy technologies, proton beams, carbon ion, intraoperative radiotherapy, radiotherapy for children, treatment of HIV-AIDS malignancies, and costing and quality management issues.

Cancer Forum

Cancer Forum
Author : Anonim
Publisher : Unknown
Release Date : 2006
Category :
Total pages :129
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Walter and Miller's Textbook of Radiotherapy: Radiation Physics, Therapy and Oncology

Walter and Miller's Textbook of Radiotherapy: Radiation Physics, Therapy and Oncology
Author : Paul R. Symonds,John A. Mills,Angela Duxbury
Publisher : Unknown
Release Date : 2019-08-21
Category :
Total pages :640
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Walter and Miller's Textbook of Radiotherapy is a key textbook for therapeutic radiography students as well as trainee clinical and medical oncologists, clinical physicists and technologists. The book is divided into 2 sections. The first section covers physics and provides a comprehensive review of radiotherapy physics. This section is designed to be non-physicist friendly, to simply and clearly explain the physical principles upon which radiotherapy and its technology are based. The second section is a systematic review by tumour site giving an up to date summary of radiotherapy practice. The title also covers the place of chemotherapy, surgery and non-radiotherapy treatments as well as the principles of cancer patient treatment including supportive care and palliative treatments. It is a comprehensive must-have resource for anyone studying therapeutic radiotherapy. Highly illustrated in full colour including 350 photographs. Clearly and simply explains the fundamental physics for clinicians Gives an up to date summary of radiotherapy practice organised by tumour site making it very easy to navigate. Describes the wide range of devices and clearly explains the principles behind their operation. Comprehensively explains the calculation models of dose predictions for treatment preparation. Heavy emphasis on how clinical trials have influenced current practice. Shows how radiobiological knowledge has influenced current practice such as the fractionation regimens for breast and prostate cancer Proton therapy; machines, dose measurement, covering the clinical advantages and pitfalls of this treatment modality. New radiotherapy modalities such as stereotactic radiotherapy, types of intensity modulated radiotherapy and imaged guided radiotherapy are comprehensively covered as are recent advances in chemotherapy and molecular targeted therapy. In depth coverage of dose measurement and new devices.

Oncology

Oncology
Author : Alfred E. Chang,Patricia A. Ganz,Daniel F. Hayes,Timothy Kinsella,Harvey I. Pass,Joan H. Schiller,Richard M. Stone,Victor Strecher
Publisher : Springer Science & Business Media
Release Date : 2007-12-08
Category : Medical
Total pages :2012
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Title consistently uses the evidence-based approach Evidence-based tables make documentation of care plan easy Interdisciplinary orientation – all aspects of patient care are covered Only book that involves experts from the entire range of cancer treatment in the fields of medical, surgical and radiation oncology Includes hot topics such as prevention and breast cancer Offers ground-breaking sections on the latest research and clinical applications in cancer survivorship Chapter on PET addresses imaging issues and how to get the best results Most comprehensive sections on the biology and epidemiology of cancer as compared to competitors

An Investigation of Accelerated Partial Breast Irradiation (APBI) for the Treatment of Early Stage Breast Cancer

An Investigation of Accelerated Partial Breast Irradiation (APBI) for the Treatment of Early Stage Breast Cancer
Author : Veeresh Michael
Publisher : Unknown
Release Date : 2017
Category :
Total pages :154
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Purpose: Breast cancer is one of the most common cancers among American women and is the second leading cause of cancer death among women in the U.S. While its incidence in Mississippi is among the lowest in the country, the state mortality rate is among the highest. Traditionally, regardless of the severity of the diagnosis, radical mastectomy followed by a combination of radiation therapy (RT) and chemotherapy was a woman's only option to treat early-stage breast cancer. The advent of breast conservation surgery (BCS) offers a less intrusive alternative and has become a popular and preferred treatment option for clinically qualified women with early stage breast cancer. Studies show lumpectomy followed by RT as equivalent to mastectomy for early stage breast cancer. Radiation Therapy is important to reduce the risk for local recurrence. BCS followed by RT is called breast conservation therapy (BCT). BCT has given rise to an accelerated or hypo-fractionated RT to the lumpectomy bed where the greatest recurrence risk exists. This treatment method, also called partial breast irradiation (PBI), allows for the breast to experience less radiation toxicity and reduces radiation treatment time. Accelerated partial breast irradiation (APBI) typically involves a radiation regimen of one week as compared to conventional whole breast irradiation requiring up to six weeks of daily radiation. Few APBI treatment techniques have gained popularity due to technical challenges and painful surgical procedures. One form that has gained favorability among physicians and patients utilizes high dose rate (HDR) brachytherapy. APBI with HDR is a two-step process involving a lumpectomy followed by surgical insertion of a balloon or strut type catheter that is used for radiation delivery. Delivery of radiation is through temporary placement of radioactive Iridium-192 within the lumpectomy site via the catheter. This outpatient procedure is typically a five-day course. A few studies have examined the impact of facility access to APBI utility. Additional studies in various states have investigated the impact of patient demographics on APBI utilization. Others have explored the association of surgeon training, physician density, and referral patterns on APBI utilization. There is currently a lack of research in APBI utilization in the state of Mississippi with respect to APBI facility access, patient demographics, and density of surgeons and radiation oncologists. Methods: Research included the analysis of Mississippi Cancer Registry (MCR) data to identify early stage breast cancer patients who received mastectomy, BCS, or BCT to include adjuvant radiation. The MCR data sought included records of early-stage breast cancer in women from 2004 to 2013, which is appropriate since APBI brachytherapy gained popularity in the last 10 years. Analysis of MCR data will correlate patient demographics to surgical and radiation treatment modality (mastectomy, BCS, or BCT). Radiation therapy facilities and the subset that offer the APBI treatment option within the state were identified through the Mississippi State Department of Health (MSDH). The Mississippi State Medical Association (MSMA) was used to identify general surgeons and radiation oncologists per county. RT facilities and physician density data was used with MCR data to classify patterns of APBI utilization within Mississippi counties. Chi-square analysis was used to investigate if radiation treatment modality selected differs by patients' race, county of diagnosis, and insurance status. Binary logistic regression was used to investigate factors associated with radiation treatment modality. Results: An analysis was performed on APBI eligible early-stage female breast cancer patients. The selection included women who received BCS and met all of the eligibility criteria for APBI treatment. Statistical analysis was performed based on demographic factors such as race, county of diagnosis, and insurance status. Additionally, statistical analysis was performed on proximity to physician density and radiation facilities within the county of diagnosis. Among APBI eligible patients, Chi-square analysis indicated a statistically significant difference for radiation treatment modality selected based on race, urban vs. rural county of diagnosis, insurance status, availability of a radiation oncologist, and availability of external beam radiation treatment facilities within the diagnosis county. Binary logistic regression analysis was performed for an outcome of no radiation versus any radiation received, as well as analysis of no radiation versus APBI brachytherapy. For both binary logistic regression analyses, there was a significant difference among treatment for patients in urban versus rural counties, race, and availability of external beam radiation facilities. For the outcome of no radiation versus brachytherapy, the availability of a surgeon or APBI brachytherapy facility within the diagnosis county showed a significant difference in treatment modality chosen. Multinomial regression analysis considered all radiation treatment modalities on controlling for all other covariates. This analysis demonstrated a statistically significant difference for any radiation treatment modality when considering race, urban versus rural county of diagnosis, and availability of external beam radiation facilities within the county. For APBI brachytherapy, the availability of a surgeon and brachytherapy facilities within the county was shown to be statistically significant.Conclusion: This study examines the variation in radiation treatment among APBI eligible early stage breast cancer patients who received mastectomy versus BCS or BCT. The analysis showed that non-Hispanic white women are significantly more likely to receive external beam treatment or APBI brachytherapy treatment than non-Hispanic black women. Women in urban counties are significantly more likely to receive external beam or APBI brachytherapy than women in rural counties. When compared to uninsured women, those who have government insurance are more likely to receive external beam or APBI brachytherapy. Also, women with private pay insurance are more likely to receive APBI brachytherapy and significantly more likely to receive external beam treatment. While not statistically significant, not having a radiation oncologist available in the county of diagnosis decreased the likelihood of receiving either external beam RT or brachytherapy. Similarly not having a surgeon available within the diagnosis county decreased the likelihood of a patient receiving external beam treatment and significantly decreased the likelihood of brachytherapy. Not having a linear accelerator available within the county of diagnosis still increases the likelihood of receiving some type of radiation treatment, especially brachytherapy. Finally, having an HDR brachytherapy facility available within the county of diagnosis significantly increases the likelihood of receiving APBI brachytherapy treatment. Non-Hispanic white women with private or government insurance are more likely to receive external beam treatment or APBI brachytherapy treatment, indicating that race and insurance status have an impact on APBI utilization. Access to a radiation oncologist did not significantly have an impact on APBI utilization; however, not having a surgeon in the county significantly decreased the likelihood of APBI utilization. Patients were over five times more likely to receive APBI brachytherapy when there was no access to an external beam Linac facility within the county of diagnosis, indicating a significant impact on APBI utilization. Access to HDR brachytherapy facilities within the county of diagnosis did not significantly impact the utility of external beam radiation therapy, but did significantly decreased the likelihood of APBI utilization. Currently, there is a lack of APBI utilization data for the state of Mississippi, and this modality has not been analyzed with respect to race, location, insurance status, and access to radiation oncologists, surgeons, and treatment facilities in our state.

Multimodal Biomedical Imaging

Multimodal Biomedical Imaging
Author : Anonim
Publisher : Unknown
Release Date : 2007
Category : Diagnostic imaging
Total pages :129
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Walter and Miller's Textbook of Radiotherapy: Radiation Physics, Therapy and Oncology - E-Book

Walter and Miller's Textbook of Radiotherapy: Radiation Physics, Therapy and Oncology - E-Book
Author : Paul R Symonds,John A Mills,Angela Duxbury
Publisher : Elsevier Health Sciences
Release Date : 2019-07-11
Category : Medical
Total pages :512
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Walter and Miller’s Textbook of Radiotherapy is a key textbook for therapeutic radiography students as well as trainee clinical and medical oncologists, clinical physicists and technologists. The book is divided into 2 sections. The first section covers physics and provides a comprehensive review of radiotherapy physics. This section is designed to be non-physicist friendly, to simply and clearly explain the physical principles upon which radiotherapy and its technology are based. The second section is a systematic review by tumour site giving an up to date summary of radiotherapy practice. The title also covers the place of chemotherapy, surgery and non-radiotherapy treatments as well as the principles of cancer patient treatment including supportive care and palliative treatments. It is a comprehensive must-have resource for anyone studying therapeutic radiotherapy. Highly illustrated in full colour including 350 photographs. Clearly and simply explains the fundamental physics for clinicians Gives an up to date summary of radiotherapy practice organised by tumour site making it very easy to navigate. Describes the wide range of devices and clearly explains the principles behind their operation. Comprehensively explains the calculation models of dose predictions for treatment preparation. Heavy emphasis on how clinical trials have influenced current practice. Shows how radiobiological knowledge has influenced current practice such as the fractionation regimens for breast and prostate cancer Proton therapy; machines, dose measurement, covering the clinical advantages and pitfalls of this treatment modality. New radiotherapy modalities such as stereotactic radiotherapy, types of intensity modulated radiotherapy and imaged guided radiotherapy are comprehensively covered as are recent advances in chemotherapy and molecular targeted therapy. In depth coverage of dose measurement and new devices.

Diagnosis and Treatment of Lung Cancer

Diagnosis and Treatment of Lung Cancer
Author : Frank C. Detterbeck,M. Patricia Rivera,Mark Socinski
Publisher : Saunders
Release Date : 2001
Category : Medical
Total pages :480
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Access comprehensive, multidisciplinary guidance on the diagnosis and treatment of lung cancer! This new resource addresses the full range of clinical issues in diagnosis, staging, and treatment, as well as the latest scientific data and evidence-based guidelines. A user-friendly organization provides quick reference to data summaries, as well as more comprehensive and detailed information for readers who wish to explore topics in depth. Features contributions by authors from many different disciplines, to ensure a balanced approach. Addresses the clinical issues seen in practice, with the inclusion of basic science research topics that are likely to be put into clinical practice soon. Integrates evidence-based medicine throughout. Assesses the strength of all available dataenabling readers to weigh different arguments and make decisions based on medical issues, values, and the availability and efficacy of interventionsusing a data rating system. Addresses difficult, but clinically relevant issues for which limited data is available. Enables readers to quickly reference findings and data in data summary statements and summary tables.

Alternating Electric Fields Therapy in Oncology

Alternating Electric Fields Therapy in Oncology
Author : Eric T. Wong
Publisher : Springer
Release Date : 2016-10-24
Category : Medical
Total pages :129
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This concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo. Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses that were performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies. Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.