March 3, 2021

Download Ebook Free Pan-genomics: Applications, Challenges, And Future Prospects

Pan-genomics: Applications, Challenges, and Future Prospects

Pan-genomics: Applications, Challenges, and Future Prospects
Author : Debmalya Barh,Siomar C. Soares,Sandeep Tiwari,Vasco Azevedo
Publisher : Academic Press
Release Date : 2020-03-06
Category : Medical
Total pages :474
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Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics, thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics , encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives Discusses current bioinformatics tools and strategies for exploiting pangenomics data Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability

Genetically Engineered Crops

Genetically Engineered Crops
Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Genetically Engineered Crops: Past Experience and Future Prospects
Publisher : National Academies Press
Release Date : 2017-01-28
Category : Science
Total pages :606
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Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.

Plant Virus-Host Interaction

Plant Virus-Host Interaction
Author : R.K. Gaur,S.M. Paul Khurana,Pradeep Sharma,Thomas Hohn
Publisher : Academic Press
Release Date : 2021-01-18
Category : Science
Total pages :582
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Plant Virus-Host Interaction: Molecular Approaches and Viral Evolution, Second Edition, provides comprehensive coverage of molecular approaches for virus-host interaction. The book contains cutting-edge research in plant molecular virology, including pathogenic viroids and transport by insect vectors, interference with transmission to control viruses, synergism with pivotal coverage of RNA silencing, and the counter-defensive strategies used by viruses to overcome the silencing response in plants. This new edition introduces new, emerging proteins involved in host-virus interactions and provides in-depth coverage of plant virus genes’ interactions with host, localization and expression. With contributions from leading experts, this is a comprehensive reference for plant virologists, molecular biologists and others interested in characterization of plant viruses and disease management. Introduces new, emerging proteins involved during the host-virus interaction and new virus strains that invade new crops through recombination, resorting and mutation Provides molecular approaches for virus-host interaction Highlights RNA silencing and counter-defensive strategies for disease management Discusses the socioeconomic implications of viral spread and mitigation techniques

Metagenomics: Techniques, Applications, Challenges and Opportunities

Metagenomics: Techniques, Applications, Challenges and Opportunities
Author : Reena Singh Chopra
Publisher : Springer Nature
Release Date : 2021
Category :
Total pages :129
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'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine

'Essentials of Cancer Genomic, Computational Approaches and Precision Medicine
Author : Nosheen Masood,Saima Shakil Malik
Publisher : Springer Nature
Release Date : 2020-03-20
Category : Medical
Total pages :499
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This book concisely describes the role of omics in precision medicine for cancer therapies. It outlines our current understanding of cancer genomics, shares insights into the process of oncogenesis, and discusses emerging technologies and clinical applications of cancer genomics in prognosis and precision-medicine treatment strategies. It then elaborates on recent advances concerning transcriptomics and translational genomics in cancer diagnosis, clinical applications, and personalized medicine in oncology. Importantly, it also explains the importance of high-performance analytics, predictive modeling, and system biology in cancer research. Lastly, the book discusses current and potential future applications of pharmacogenomics in clinical cancer therapy and cancer drug development.

The Chickpea Genome

The Chickpea Genome
Author : Rajeev K. Varshney,Mahendar Thudi,Fred Muehlbauer
Publisher : Springer
Release Date : 2018-01-02
Category : Science
Total pages :142
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This book sheds new light on the chickpea genome sequencing and resequencing of chickpea germplasm lines and provides insights into classical genetics, cytogenetics, and trait mapping. It also offers an overview of the latest advances in genome sequencing and analysis. The growing human population, rapid climate changes and limited amounts of arable land are creating substantial challenges in connection with the availability and affordability of nutritious food for smallholder farmers in developing countries. In this context, climate smart crops are essential to alleviating the hunger of the millions of poor and undernourished people living in developing countries. In addition to cereals, grain legumes are an integral part of the human diet and provide sustainable income for smallholder farmers in the arid and semi-arid regions of the world. Among grain legumes, the chickpea (Cicer arietinum) is the second most important in terms of production and productivity. Besides being a rich source of proteins, it can fix atmospheric nitrogen through symbiosis with rhizobia and increase the input of combined nitrogen. Several abiotic stresses like drought, heat, salinity, together with biotic stresses like Fusarium wilt, Ascochyta blight, and Botrytis grey mould have led to production losses, as the chickpeas is typically grown in the harsh climates of our planet’s semi-arid regions.

Bioinformatics

Bioinformatics
Author : Ibrokhim Y. Abdurakhmonov
Publisher : BoD – Books on Demand
Release Date : 2016-07-27
Category : Science
Total pages :268
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An interdisciplinary bioinformatics science aims to develop methodology and analysis tools to explore large-volume of biological data using conventional and modern computer science, statistics, and mathematics, as well as pattern recognition, reconstruction, machine learning, simulation and iterative approaches, molecular modeling, folding, networking, and artificial intelligence. Written by international team of life scientists, this Bioinformatics book provides some updates on bioinformatics methods, resources, approaches, and genome analysis tools useful for molecular sciences, medicine and drug designs, as well as plant sciences and agriculture. I trust chapters of this book should provide advanced knowledge for university students, life science researchers, and interested readers on some latest developments in the bioinformatics field.

Human Genome Editing

Human Genome Editing
Author : National Academies of Sciences, Engineering, and Medicine,National Academy of Medicine,National Academy of Sciences,Committee on Human Gene Editing: Scientific, Medical, and Ethical Considerations
Publisher : National Academies Press
Release Date : 2017-08-13
Category : Medical
Total pages :328
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Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

Advances in Microbial Biotechnology

Advances in Microbial Biotechnology
Author : Pradeep Kumar, PhD.,Jayanta Kumar Patra,Pranjal Chandra
Publisher : CRC Press
Release Date : 2018-10-03
Category : Medical
Total pages :574
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Over the last few decades, the rapid and vast development of advanced microbial bioresources and metagenomics techniques has completely transformed the field of microbial biotechnology. Our understanding of microbial diversity, evolutionary biology, and microbial interaction with their animal and plant hosts at molecular level has been revolutionized with an abundance of new research. This new volume, Advances in Microbial Biotechnology: Current Trends and Future Prospect, focuses on the application of microorganisms for several purposes: for plant protection and improvement, for environmental remediation purposes, and for the improvement of human health. Various applications of microorganisms are covered broadly and have been appropriately reflected in depth in different chapters. The book is divided into four major sections: applied microbiology in agriculture microbes in the environment microbes in human health microbes in nanotechnology The book provides insight into the diverse microorganisms that have been explored and exploited in the development of various applications for agricultural improvements. The book also looks at the application of microbes for the removal of pollutants and the recovery of metals and oils. Also discussed is the detection and exploitation of microorganisms in the diagnosis of human diseases, providing possible holistic approaches to health. This new volume will provide a wealth of information on new research on the application of microbial biotechnology today.

Human Germline Modification and the Right to Science

Human Germline Modification and the Right to Science
Author : Andrea Boggio,Cesare P. R. Romano,Jessica Almqvist
Publisher : Cambridge University Press
Release Date : 2020-01-09
Category : Law
Total pages :324
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A survey of the regulation of human germline genome modification in eighteen countries and the emerging international standards.

Genetics, Genomics and Breeding of Conifers

Genetics, Genomics and Breeding of Conifers
Author : Christophe Plomion,Jean Bousquet,Chittaranjan Kole
Publisher : CRC Press
Release Date : 2011-08-10
Category : Science
Total pages :484
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With contributions by internationally reputed researchers in the field, this book presents the implications of the genomic revolution for conifers—promoting a better understanding of the evolution of these organisms as well as new knowledge about the molecular basis of quantitative trait variation. Both of these discoveries play important roles in their domestication. Topics include cytogenetics, patterns of nucleotide diversity, genetic mapping, integration of molecular markers in breeding, transcriptomics, advances in proteomics and metabolomics in gymnosperms, and economic importance.

Encyclopedia of Food Microbiology

Encyclopedia of Food Microbiology
Author : Carl A. Batt
Publisher : Academic Press
Release Date : 2014-04-02
Category : Technology & Engineering
Total pages :3248
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Written by the world's leading scientists and spanning over 400 articles in three volumes, the Encyclopedia of Food Microbiology, Second Edition is a complete, highly structured guide to current knowledge in the field. Fully revised and updated, this encyclopedia reflects the key advances in the field since the first edition was published in 1999 The articles in this key work, heavily illustrated and fully revised since the first edition in 1999, highlight advances in areas such as genomics and food safety to bring users up-to-date on microorganisms in foods. Topics such as DNA sequencing and E. coli are particularly well covered. With lists of further reading to help users explore topics in depth, this resource will enrich scientists at every level in academia and industry, providing fundamental information as well as explaining state-of-the-art scientific discoveries. This book is designed to allow disparate approaches (from farmers to processors to food handlers and consumers) and interests to access accurate and objective information about the microbiology of foods. Microbiology impacts the safe presentation of food. From harvest and storage to determination of shelf-life, to presentation and consumption. This work highlights the risks of microbial contamination and is an invaluable go-to guide for anyone working in Food Health and Safety. Has a two-fold industry appeal (1) those developing new functional food products and (2) to all corporations concerned about the potential hazards of microbes in their food products.

Molecular Medical Microbiology, Three-Volume Set

Molecular Medical Microbiology, Three-Volume Set
Author : Yi-Wei Tang,Dongyou Liu,Ian Poxton,Joseph Schwartzman,Max Sussman
Publisher : Elsevier
Release Date : 2001-10-23
Category : Science
Total pages :2223
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The molecular age has brought about dramatic changes in medical microbiology, and great leaps in our understanding of the mechanisms of infectious disease. Molecular Medical Microbiology is the first book to synthesise the many new developments in both molecular and clinical research in a single comprehensive resource. This timely and authoritative 3-volume work is an invaluable reference source of medical bacteriology. Comprising over 100 chapters, organised into 17 major sections, the scope of this impressive work is wide-ranging. Written by experts in the field, chapters include cutting edge information, and clinical overviews for each major bacterial group, in addition to the latest updates on vaccine development, molecular technology and diagnostic technology. * The first comprehensive and accessible reference on Molecular Medical Microbiology * Two color presentation throughout * Full colour plate section * Fully integrated and meticulously organised * In depth discussion of individual pathogenic bacteria in a system-oriented approach * Includes a clinical overview for each major bacterial group * Presents the latest information on vaccine development, molecular technology and diagnostic technology * Extensive indexing and cross-referencing throughout * Over 100 chapters covering all major groups of bacteria * Written by an international panel of authors expert in their respective disciplines * Over 2300 pages in three volumes

Cancer Evolution

Cancer Evolution
Author : Charles Swanton
Publisher : Perspectives Cshl
Release Date : 2017
Category : Medical
Total pages :350
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Tumor progression is driven by mutations that confer growth advantages to different subpopulations of cancer cells. As a tumor grows, these subpopulations expand, accumulate new mutations, and are subjected to selective pressures from the environment, including anticancer interventions. This process, termed clonal evolution, can lead to the emergence of therapy-resistant tumors and poses a major challenge for cancer eradication efforts. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines cancer progression as an evolutionary process and explores how this way of looking at cancer may lead to more effective strategies for managing and treating it. The contributors review efforts to characterize the subclonal architecture and dynamics of tumors, understand the roles of chromosomal instability, driver mutations, and mutation order, and determine how cancer cells respond to selective pressures imposed by anticancer agents, immune cells, and other components of the tumor microenvironment. They compare cancer evolution to organismal evolution and describe how ecological theories and mathematical models are being used to understand the complex dynamics between a tumor and its microenvironment during cancer progression. The authors also discuss improved methods to monitor tumor evolution (e.g., liquid biopsies) and the development of more effective strategies for managing and treating cancers (e.g., immunotherapies). This volume will therefore serve as a vital reference for all cancer biologists as well as anyone seeking to improve clinical outcomes for patients with cancer.

Big Data Analytics in Genomics

Big Data Analytics in Genomics
Author : Ka-Chun Wong
Publisher : Springer
Release Date : 2016-10-24
Category : Computers
Total pages :428
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This contributed volume explores the emerging intersection between big data analytics and genomics. Recent sequencing technologies have enabled high-throughput sequencing data generation for genomics resulting in several international projects which have led to massive genomic data accumulation at an unprecedented pace. To reveal novel genomic insights from this data within a reasonable time frame, traditional data analysis methods may not be sufficient or scalable, forcing the need for big data analytics to be developed for genomics. The computational methods addressed in the book are intended to tackle crucial biological questions using big data, and are appropriate for either newcomers or veterans in the field.This volume offers thirteen peer-reviewed contributions, written by international leading experts from different regions, representing Argentina, Brazil, China, France, Germany, Hong Kong, India, Japan, Spain, and the USA. In particular, the book surveys three main areas: statistical analytics, computational analytics, and cancer genome analytics. Sample topics covered include: statistical methods for integrative analysis of genomic data, computation methods for protein function prediction, and perspectives on machine learning techniques in big data mining of cancer. Self-contained and suitable for graduate students, this book is also designed for bioinformaticians, computational biologists, and researchers in communities ranging from genomics, big data, molecular genetics, data mining, biostatistics, biomedical science, cancer research, medical research, and biology to machine learning and computer science. Readers will find this volume to be an essential read for appreciating the role of big data in genomics, making this an invaluable resource for stimulating further research on the topic.