December 2, 2020

Download Ebook Free Personalized Immunosuppression In Transplantation

Personalized Immunosuppression in Transplantation

Personalized Immunosuppression in Transplantation
Author : Michael Oellerich,Amitava Dasgupta
Publisher : Elsevier
Release Date : 2015-08-08
Category : Medical
Total pages :316
GET BOOK

Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity. This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful. Focuses on the personalized management of immunosuppression therapy in individual transplant patients Presents information that applies to many areas, including gmass spectrometry, assay design, assay validation, clinical chemistry, and clinical pathology Provides practical guidelines for the initial selection and subsequent modifications of immunosuppression therapy in individual transplant patients Reviews the latest research in biomarker monitoring in personalizing immunosuppressant therapy, including potential new markers not currently used, but with great potential for future use Explains how monitoring graft-derived, circulating, cell free DNA has shown promise in the early detection of transplant injury in liquid biopsy

Personalized Immunosuppression in Transplantation

Personalized Immunosuppression in Transplantation
Author : Michael Oellerich,Amitava Dasgupta, PhD, DABCC
Publisher : Elsevier
Release Date : 2015-09-17
Category : Medical
Total pages :316
GET BOOK

Personalized Immunosuppression in Transplantation: Role of Biomarker Monitoring and Therapeutic Drug Monitoring provides coverage of the various approaches to monitoring immunosuppressants in transplant patients, including the most recently developed biomarker monitoring methods, pharmacogenomics approaches, and traditional therapeutic drug monitoring. The book is written for pathologists, toxicologists, and transplant surgeons who are involved in the management of transplant patients, offering them in-depth coverage of the management of immunosuppressant therapy in transplant patients with the goal of maximum benefit from drug therapy and minimal risk of drug toxicity. This book also provides practical guidelines for managing immunosuppressant therapy, including the therapeutic ranges of various immunosuppressants, the pitfalls of methodologies used for determination of these immunosuppressants in whole blood or plasma, appropriate pharmacogenomics testing for organ transplant recipients, and when biomarker monitoring could be helpful. Focuses on the personalized management of immunosuppression therapy in individual transplant patients Presents information that applies to many areas, including gmass spectrometry, assay design, assay validation, clinical chemistry, and clinical pathology Provides practical guidelines for the initial selection and subsequent modifications of immunosuppression therapy in individual transplant patients Reviews the latest research in biomarker monitoring in personalizing immunosuppressant therapy, including potential new markers not currently used, but with great potential for future use Explains how monitoring graft-derived, circulating, cell free DNA has shown promise in the early detection of transplant injury in liquid biopsy

Gastrointestinal Transplantation, An Issue of Gastroenterology Clinics of North America, E-Book

Gastrointestinal Transplantation, An Issue of Gastroenterology Clinics of North America, E-Book
Author : Enrico Benedetti,Ivo G. Tzvetanov
Publisher : Elsevier Health Sciences
Release Date : 2018-05-16
Category : Medical
Total pages :129
GET BOOK

The Guest Editors have put together a concise monograph on the latest advances in transplantation of the liver, intestine, and pancreas. Expert authors have written comprehensive reviews on the following topics: Living donor liver transplantation: Technical innovations; Liver transplantation for cholangiocarcinoma; Immunological monitoring to personalize immunosuppression after liver transplantation; Status of adult LDLT in US based on A2ALL; Pediatric liver transplantation; Modern treatment of fulminant liver failure; Intestinal failure and rehabilitation; Adult intestinal transplantation; Pediatric intestinal transplantation; Living donor intestinal transplantation; Endoscopic follow-up of intestinal transplant recipients; Multivisceral transplantation; Pancreas transplantation for DM1 and DM2; and Robotic pancreas transplantation. Readers will come away with the clinical information they need to stay current on issues surrounding gastrointestinal transplantations.

Disease Recurrence After Liver Transplantation

Disease Recurrence After Liver Transplantation
Author : Paul J. Thuluvath
Publisher : Springer
Release Date : 2015-11-11
Category : Medical
Total pages :269
GET BOOK

As there is a high incidence of disease recurrence after liver transplantation, this volume is designed around the need for a reference text dealing exclusively with this problem. The book places special emphasis on pre- and post-transplant predictors of recurrence, severity assessment, prophylaxis, and treatment. Pathobiology of disease recurrence is discussed in detail where applicable. Issues including quality of life and cost burden are also covered in the text. Written by well-known authorities in each field, Disease Recurrence After Liver Transplantation: Natural History, Treatment and Survival serves as a comprehensive reference for physicians and surgeons who take care of liver transplant recipients and a major addition to the literature detailing the current understanding of disease recurrence.

Textbook of Personalized Medicine

Textbook of Personalized Medicine
Author : Kewal K. Jain
Publisher : Springer Science & Business Media
Release Date : 2009-08-29
Category : Medical
Total pages :430
GET BOOK

Personalized medicine, which simply means selection of treatment best suited for an individual, involves integration and translation of several new technologies in clinical care of patients. The scope is much broader than indicated by the term genomic medicine because many non-genomic factors are taken into consideration in developing personalized medicine. Basic technologies for personalized medicine, of which molecular diagnostics has the biggest share, are mentioned briefly and appropriate references are given for further information. Commercial aspects are discussed briefly in a chapter and detailed analysis of markets and companies involved in personalized medicine is presented in a special report on this topic. There is increasing interest in personalized medicine. Considerable advances have taken place in molecular biology and biotechnology to make personalized medicine a viable option, but some misconceptions still exist, both in the academic and commercial sectors. There is lack of a suitable source of information that provides both the fundamentals as well as applications of personalized medicine. As the latest version of the first monograph on personalized medicine published in 1998, this volume, Textbook of Personalized Medicine, summarizes the author’s efforts during the past decade, as well as reviews selected studies done during this period in a readable format for the physicians and scientists. It is hoped that physicians, pharmacists, scientists and interested lay readers with basic scientific knowledge will find this book useful.

Organ Donation and Transplantation

Organ Donation and Transplantation
Author : Georgios Tsoulfas
Publisher : BoD – Books on Demand
Release Date : 2018-07-25
Category : Medical
Total pages :452
GET BOOK

One of the most interesting and at the same time most challenging fields of medicine and surgery has been that of organ donation and transplantation. It is a field that has made tremendous strides during the last few decades through the combined input and efforts of scientists from various specialties. What started as a dream of pioneers has become a reality for the thousands of our patients whose lives can now be saved and improved. However, at the same time, the challenges remain significant and so do the expectations. This book will be a collection of chapters describing these same challenges involved including the ethical, legal, and medical issues in organ donation and the technical and immunological problems the experts are facing involved in the care of these patients.The authors of this book represent a team of true global experts on the topic. In addition to the knowledge shared, the authors provide their personal clinical experience on a variety of different aspects of organ donation and transplantation.

Pediatric Liver Transplantation E-Book

Pediatric Liver Transplantation E-Book
Author : Nedim Hadzic,Ulrich Baumann,Valérie MCLIN
Publisher : Elsevier Health Sciences
Release Date : 2020-11-13
Category : Medical
Total pages :512
GET BOOK

Written and edited by global leaders in the field, Pediatric Liver Transplantation: A Clinical Guide covers all aspects of treatment and management regarding this multifaceted procedure and unique patient population. This practical reference offers detailed, focused guidance in a highly templated, easy-to-consult format, covering everything from pre-transplantation preparation to surgical techniques to post-operative complications. Provides an in-depth understanding of all aspects of pediatric liver transplantation, ideal for pediatric hepatologists, pediatric transplant surgeons, and others on the pediatric transplant team. Covers all surgical techniques in detail, including split graft, living related, auxiliary, and domino. Discusses pediatric liver transplantation consideration for an increasing number of additional metabolic, hematologic and renal conditions; breakthroughs in grafting and stem cell therapy; and techniques and present role of hepatocyte transplantation. Uses a quick-reference templated format; each chapter includes an overview, pathophysiology, conventional management, controversies, and bulleted summary of key take-aways. Includes state-of-the-art mini-reviews based on updated references and author experience throughout the text. Features a full-color design with numerous algorithms, figures, and radiological and histopathological photos.

Kidney Transplantation

Kidney Transplantation
Author : Massimiliano Veroux
Publisher : Bentham Science Publishers
Release Date : 2012-08
Category : Medical
Total pages :398
GET BOOK

This e-book is an overview of recent advances in the realm of kidney transplantation. The volume discusses developments in surgical procedures while presenting a perspective on possibilities for kidney transplant research in the future. The e-book is a c

Genetic Diversity and Disease Susceptibility

Genetic Diversity and Disease Susceptibility
Author : Yamin Liu
Publisher : BoD – Books on Demand
Release Date : 2018-10-17
Category : Medical
Total pages :164
GET BOOK

Polymorphism or variation in DNA sequence can affect individual phenotypes such as color of skin or eyes, susceptibility to diseases, and response to drugs, vaccines, chemicals, and pathogens. Especially, the interfaces between genetics, disease susceptibility, and pharmacogenomics have recently been the subject of intense research activity. This book is a self-contained collection of valuable scholarly papers related to genetic diversity and disease susceptibility, pharmacogenomics, ongoing advances in technology, and analytic methods in this field. The book contains nine chapters that cover the three main topics of genetic polymorphism, genetic diversity, and disease susceptibility and pharmacogenomics. Hence, this book is particularly useful to academics, scientists, physicians, pharmacists, practicing researchers, and postgraduate students whose work relates to genetic polymorphisms.

Frontiers in Transplantology

Frontiers in Transplantology
Author : Hesham Abdeldayem,Ahmed El-Kased,Ehab El-Shaarawy
Publisher : BoD – Books on Demand
Release Date : 2016-09-07
Category : Medical
Total pages :310
GET BOOK

This book is addressed to researchers, practicing physicians, and surgeons in the field of organ transplantation, as well as the medical students, residents, and fellows. The topics covered include the religious concepts in organ transplantation, embryonic organ transplantation, tolerance, normothermic graft perfusion, pharmacogenetics of immunosuppressors, viral transmission in organ transplantation, pediatric and split-liver transplantation, portopulmonary hypertension, mechanical circulatory support, ex vivo lung perfusion, and ABO-incompatible kidney transplantation.

Missing Data in Clinical Studies

Missing Data in Clinical Studies
Author : Geert Molenberghs,Michael Kenward
Publisher : John Wiley & Sons
Release Date : 2007-04-04
Category : Medical
Total pages :526
GET BOOK

Missing Data in Clinical Studies provides a comprehensive account of the problems arising when data from clinical and related studies are incomplete, and presents the reader with approaches to effectively address them. The text provides a critique of conventional and simple methods before moving on to discuss more advanced approaches. The authors focus on practical and modeling concepts, providing an extensive set of case studies to illustrate the problems described. Provides a practical guide to the analysis of clinical trials and related studies with missing data. Examines the problems caused by missing data, enabling a complete understanding of how to overcome them. Presents conventional, simple methods to tackle these problems, before addressing more advanced approaches, including sensitivity analysis, and the MAR missingness mechanism. Illustrated throughout with real-life case studies and worked examples from clinical trials. Details the use and implementation of the necessary statistical software, primarily SAS. Missing Data in Clinical Studies has been developed through a series of courses and lectures. Its practical approach will appeal to applied statisticians and biomedical researchers, in particular those in the biopharmaceutical industry, medical and public health organisations. Graduate students of biostatistics will also find much of benefit.

Transplant International Official Journal of the European Society for Organ Transplantation

Transplant International Official Journal of the European Society for Organ Transplantation
Author : Anonim
Publisher : Springer Science & Business Media
Release Date : 2013-11-11
Category : Medical
Total pages :733
GET BOOK

This supplement to Transplant International contains the Proceedings of the successful 5th Congress of the European Society for Organ Transplantation held in Maastricht from 7-10 October 1991. Of 827 abstracts submitted to the congress, 548 were selected by the Scien tific Committee for either oral or poster presentation. Of these 548 presenta tions, the guest editors selected 212 full papers for publication in this book. Two aspects are important where proceedings are concerned-the quality of the papers and the speed of publication. I thank our authors and guest editors, whose combined expertise has given us a guarantee of quality. I also thank our editorial and production teams for their tremendous efforts to hasten editing, proofreading, printing, and publication. In particular, I would like to express my gratitude to Maurits Booster, M.D., and Sylvia van Roosmalen for their assist ance and support in seeing this supplement through to completion. As a concession to time, we have waived some of our stringent rules of style and limited our correspondence with authors by, for example, page proofs being reviewed and corrected in house only. This enables us to publish two months earlier but has the disadvantage that, given the allotted time, we have not been able to ensure that each and every article has an abstract, nor that every "i" has been dotted in the reference lists or in the addresses/institute affiliations of all the authors.

Solid Organ Transplantation in Infants and Children

Solid Organ Transplantation in Infants and Children
Author : Stephen P. Dunn,Simon Horslen
Publisher : Unknown
Release Date : 2020
Category : Transplantation of organs, tissues, etc. in children
Total pages :129
GET BOOK

Regenerative Medicine Applications in Organ Transplantation

Regenerative Medicine Applications in Organ Transplantation
Author : Giuseppe Orlando
Publisher : Academic Press
Release Date : 2013-10-11
Category : Technology & Engineering
Total pages :1050
GET BOOK

Regenerative Medicine Applications in Organ Transplantation illustrates exactly how these two fields are coming together and can benefit one another. It discusses technologies being developed, methods being implemented, and which of these are the most promising. The text encompasses tissue engineering, biomaterial sciences, stem cell biology, and developmental biology, all from a transplant perspective. Organ systems considered include liver, renal, intestinal, pancreatic, and more. Leaders from both fields have contributed chapters, clearly illustrating that regenerative medicine and solid organ transplantation speak the same language and that both aim for similar medical outcomes. The overall theme of the book is to provide insight into the synergy between organ transplantation and regenerative medicine. Recent groundbreaking achievements in regenerative medicine have received unprecedented coverage by the media, fueling interest and enthusiasm in transplant clinicians and researchers. Regenerative medicine is changing the premise of solid organ transplantation, requiring transplantation investigators to become familiar with regenerative medicine investigations that can be extremely relevant to their work. Similarly, regenerative medicine investigators need to be aware of the needs of the transplant field to bring these two fields together for greater results. Bridges the gap between regenerative medicine and solid organ transplantation and highlights reasons for collaboration Explains the importance and future potential of regenerative medicine to the transplant community Illustrates to regenerative medicine investigators the needs of the transplant discipline to drive and guide investigations in the most promising directions

Rejection and Tolerance

Rejection and Tolerance
Author : J.-L. Touraine,J. Traeger,H. Bétuel,J.-M. Dubernard
Publisher : Springer Science & Business Media
Release Date : 1994
Category : Medical
Total pages :459
GET BOOK

Proceedings of the 25th Conference on Transplantation and Clinical Immunology 24--26 May 1993