April 13, 2021

Download Ebook Free Platelets

Platelets

Platelets
Author : Alan D. Michelson
Publisher : Elsevier
Release Date : 2011-08-29
Category : Medical
Total pages :1376
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PLATELETS is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource. · First edition won Best Book in Medical Science Award from the Association of American Publishers · Contains fourteen new chapters on topics such as platelet genomics and proteomics, inhibition of platelet function by the endothelium, clinical tests of platelet function, real time in vivo imaging of platelets, and inherited thrombocytopenias · A comprehensive full color reference comprising over 70 chapters, 1400 pages, and 16,000 references

Clinical Application of Radiolabelled Platelets

Clinical Application of Radiolabelled Platelets
Author : C. Kessler,M.R. Hardeman,H. Henningsen,J. Petrovici
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :301
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AIMS OF THE COLOGNE-SYMPOSIUM ON RADIOLABELLED PLATELETS In 1976, M. Thakur et al (1) were the first to publish a paper concerning the in vivo thrombus detection with 111- In-labelled platelets. Previous attempts at scintigraphic thrombus localisation had been disappointing because of the unspecific binding of a number of the isotopes used, as well as the poor labelling efficiency or an insufficient low gamma-emitting property. Because of its physical characteristics (2.8 days half-life, 94% gamma emission) 111 Indium turned out to be the best isotope for platelet kinetic studies as well as for the measurement of platelet incorporation by Thrombi to be used up until now. The lipophile complexes of Ill-In (8-hydroxyquinoline, acetylacetone, tropolone) diffuse passively into the platelets without altering the function or the life span of the platelets. This advantage has let to an increase in the clinical applications of 1211-In labelled platelets. Today, radiolabelled platelets are used for thrombus detection in several different medical areas such as cardiology, nephrology. angiology or neurology. Even though many scientists and hospital doctors now routinely use radiolabelled platelet as a diagnostic tool, there is as yet not a standardized labelling method. In addition to this, there are neither standardized image procedures for the different clinical applications nor an agreement about specificity and sensitivity of the method. In 1983, a symposium on Radiolabelled Cellular Blood Elements was organized by M.Thakur, M.R.Hardeman and M.D.

Platelet Function Testing

Platelet Function Testing
Author : H. James Day,Holm Holmsen,Marjorie Bass Zucker
Publisher : Unknown
Release Date : 1978
Category : Blood platelet aggregation
Total pages :751
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Medical Subject Headings

Medical Subject Headings
Author : National Library of Medicine (U.S.)
Publisher : Unknown
Release Date : 1995
Category : Subject headings
Total pages :129
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Cumulated Index Medicus

Cumulated Index Medicus
Author : Anonim
Publisher : Unknown
Release Date : 2000
Category : Medicine
Total pages :129
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Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute

Subject Index of Current Research Grants and Contracts Administered by the National Heart, Lung and Blood Institute
Author : National Heart, Lung, and Blood Institute
Publisher : Unknown
Release Date : 1977
Category : Cardiovascular research
Total pages :129
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Interaction of Platelets with the Vessel Wall

Interaction of Platelets with the Vessel Wall
Author : John A. Oates,Jacek Hawiger,Russell Ross
Publisher : Unknown
Release Date : 1985
Category : Blood platelet aggregation
Total pages :172
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Fibrillar Deposition of Plasma Fibronectin by Adherent Platelets

Fibrillar Deposition of Plasma Fibronectin by Adherent Platelets
Author : Jaehyung Cho
Publisher : Unknown
Release Date : 2006
Category :
Total pages :209
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Platelets and Their Factors

Platelets and Their Factors
Author : Franz von Bruchhausen,Ulrich Walter
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :753
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Platelets playa fundamental, life-saving role in hemostasis and blood clotting at sites of vascular injury. Unwanted platelet activation and arterial thombus formation are, however, implicated in the onset of myocardial infarction, stroke, and other cardiovascular diseases. Acceptance that platelets play a major role in the pathogenesis of atherosclerosis including coronary heart disease has revolutionized the pharmacological treatment of cardiovascular diseases, and aspirin is now an essential antiplatelet drug and the golden standard for future developments. Yet the search for better and perhaps safer antiplatelet drugs is one of the most active areas of investigation in both basic and clinical research. Platelets, especially human platelets, have also emerged as one of the major models for the study of inter- and intracellular signal transduction pathways. Many biochemists, cell biologists, pharmacologists, pathologists, hematologists, and cardiologists find platelets useful for studying processes such as adhesion, inside-out and outside-in signalling through the plasma membrane, channels, calcium homeostasis, protein kinases, the network of intracellular signal transduction cascades, and the release of vasoactive substances. The aim of the editors has been to compile chapters summarizing the current state-of-the-art information on the biochemistry, cell biology, pharmacology, and physiologic and pathophysiologic roles of human platelets. We hope that this volume represents the major aspects of current platelet research although it is perhaps inevitable that certain areas are covered less thoroughly than others. We would like to acknowledge the excellent help and support of the Springer-Verlag staff, in particular that of Ms. Doris Walker.

The Non-Thrombotic Role of Platelets in Health and Disease

The Non-Thrombotic Role of Platelets in Health and Disease
Author : Steve W. Kerrigan,Niamh Moran
Publisher : BoD – Books on Demand
Release Date : 2015-11-18
Category : Medical
Total pages :248
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Platelets play a key role in thrombosis and haemostasis. However recent evidence clearly demonstrates that the functional role of platelets extends to many other processes in the body. With an internationally recognised list of contributing authors, The Non-Thrombotic Role of Platelets in Health and Disease, is a unique and definitive source of state-of-the-art knowledge about the additional role of platelets outside thrombosis and haemostasis. The intended audience for The Non-Thrombotic Role of Platelets in Health and Disease includes platelet biologists, microbiologists, immunologists, haematologists, oncologists, respiratory physicians, cardiologists, neurobiologists, tissue engineers, as well as students and fellows in these areas.

Federation Proceedings

Federation Proceedings
Author : Federation of American Societies for Experimental Biology
Publisher : Unknown
Release Date : 1962
Category : Biology
Total pages :129
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Biochemistry of Blood Platelets

Biochemistry of Blood Platelets
Author : Federation of European Biochemical Societies. Meeting,Federation of European Biochemical Societies
Publisher : Academic Press
Release Date : 1967
Category : Blood
Total pages :191
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Platelets in Cardiovascular Disease

Platelets in Cardiovascular Disease
Author : Deepak L. Bhatt
Publisher : Imperial College Press
Release Date : 2008
Category : Medical
Total pages :218
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Platelets in Cardiovascular Disease provides an in-depth and current coverage of relevant platelet biology and antiplatelet therapy that is in clinical use today and potentially for the future. The book provides a succinct overview of the critical role of platelets in cardiovascular medicine.Cardiovascular disease is the leading cause of mortality worldwide, and recent research has found that the platelet is central to the genesis of heart attacks and stroke as well as many of the complications of angioplasty and bypass surgery. An explosion of knowledge of the biology of platelets has established their important role in the formation of blood clots and, perhaps more intriguingly, their role as inflammatory cells. This growth in information has been paralleled by the development of several drugs that can interfere with platelet action and thereby improve patient outcomes. Indeed, several antiplatelet drugs already in development may ultimately lead to marked advances in both the treatment and prevention of cardiovascular disease.Drawing upon a panel of international experts, Platelets in Cardiovascular Disease delivers a concise yet thorough review of the major developments in antiplatelet therapy. Practicing clinicians as well as those involved in the development of new antithrombotic therapies will find the book interesting and useful.

The Histogenesis of the Blood Platelets

The Histogenesis of the Blood Platelets
Author : James Homer Wright
Publisher : Sagwan Press
Release Date : 2015-08-23
Category : History
Total pages :26
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This work has been selected by scholars as being culturally important, and is part of the knowledge base of civilization as we know it. This work was reproduced from the original artifact, and remains as true to the original work as possible. Therefore, you will see the original copyright references, library stamps (as most of these works have been housed in our most important libraries around the world), and other notations in the work. This work is in the public domain in the United States of America, and possibly other nations. Within the United States, you may freely copy and distribute this work, as no entity (individual or corporate) has a copyright on the body of the work. As a reproduction of a historical artifact, this work may contain missing or blurred pages, poor pictures, errant marks, etc. Scholars believe, and we concur, that this work is important enough to be preserved, reproduced, and made generally available to the public. We appreciate your support of the preservation process, and thank you for being an important part of keeping this knowledge alive and relevant.

Platelets and Megakaryocytes

Platelets and Megakaryocytes
Author : Jonathan M. Gibbins,Martyn P. Mahaut-Smith
Publisher : Springer Science & Business Media
Release Date : 2004
Category : Blood platelets
Total pages :888
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Platelets are an essential element of the body's hemostasis system, and yet, through their involvement in thrombosis, are also a major cause of morbidity and mortality. Platelets have a limited lifespan and must be continually manufactured by their precursor, the megakaryocyte. In Platelets and Megakaryocytes, Volume 2: Perspectives and Techniques leading expert researchers-many responsible for seminal discoveries in the field-offer basic and advanced techniques for studying cell signaling in the regulation and function of platelets and megakaryocytes, as well as state-of-the-art commentaries on our understanding of these cells. The methods include ligand-binding assays, the study of protein and lipid kinases and phosphatases, the analysis of lipid rafts in the regulation of cell signaling, and the measurement of intracellular calcium levels. There are also techniques for the study of electrophysiological events, nitric oxide signaling, venom proteins, and for the internalization of proteins into platelets through permeabilization. The application of many molecular and post-genomic methods to the study of platelets and megakaryocytes is also described. All protocols follow the successful Methods in Molecular BiologyTM series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. A companion volume, Platelets and Megakaryocytes, Volume 1: Functional Assays describes in step-by-step detail basic and advanced techniques for analyzing platelet and megakaryocyte function. Comprehensive and cutting-edge, the two volumes of Platelets and Megakaryocytes offer novice and experienced cell biologists, hematologists, and clinicians not only a benchmark survey of the field, but also a comprehensive library of proven techniques essential for productive research on platelets and megakaryocytes today.