November 28, 2020

Download Ebook Free Practical Approaches To Biological Inorganic Chemistry

Practical Approaches to Biological Inorganic Chemistry

Practical Approaches to Biological Inorganic Chemistry
Author : Robert R. Crichton,Ricardo O. Louro
Publisher : Newnes
Release Date : 2012-12-31
Category : Science
Total pages :336
GET BOOK

The book reviews the use of spectroscopic and related methods to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique including relevant theory, clearly explains what it is and how it works and then presents how the technique is actually used to evaluate biological structures. Practical examples and problems are included to illustrate each technique and to aid understanding. Designed for students and researchers who want to learn both the basics, and more advanced aspects of bioinorganic chemistry. Many colour illustrations enable easier visualization of molecular mechanisms and structures Worked examples and problems are included to illustrate and test the reader’s understanding of each technique Written by a multi-author team who use and teach the most important techniques used today to analyse complex biological structures

Practical Approaches to Biological Inorganic Chemistry

Practical Approaches to Biological Inorganic Chemistry
Author : Robert R. Crichton,Ricardo O. Louro
Publisher : Elsevier
Release Date : 2019-09-10
Category : Science
Total pages :504
GET BOOK

Practical Approaches to Biological Inorganic Chemistry, Second Edition, reviews the use of spectroscopic and related analytical techniques to investigate the complex structures and mechanisms of biological inorganic systems that contain metals. Each chapter presents an overview of the technique, including relevant theory, a clear explanation of what it is, how it works, and how the technique is actually used to evaluate biological structures. New chapters cover Raman Spectroscopy and Molecular Magnetochemistry, but all chapters have been updated to reflect the latest developments in discussed techniques. Practical examples, problems and many color figures are also included to illustrate key concepts. The book is designed for researchers and students who want to learn both the basics and more advanced aspects of key methods in biological inorganic chemistry. Presents new chapters on Raman Spectroscopy and Molecular Magnetochemistry, as well as updated figures and content throughout Includes color images throughout to enable easier visualization of molecular mechanisms and structures Provides worked examples and problems to help illustrate and test the reader’s understanding of each technique Written by leading experts who use and teach the most important techniques used today to analyze complex biological structures

Biological Inorganic Chemistry

Biological Inorganic Chemistry
Author : Robert R. Crichton
Publisher : Academic Press
Release Date : 2018-05-23
Category : Science
Total pages :692
GET BOOK

Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students. Includes a thorough survey of metals in biological systems: in the human body, in medicine and in the environment Previous winner (Second Edition) of the 2013 Textbook Excellence Award (Texty) from the Text and Academic Authors Association Features new sections: an overview of the different functions of essential metal ions; toxic metals in diagnosis and therapeutics; crystal and ligand field theory and their limitations; molecular orbital theory; genetic and molecular biological approaches to study metals; more complex cofactors and their biosynthesis; photosynthetic oxidation of water; man-made environmental pollution; and metals as poisons

Computational Inorganic and Bioinorganic Chemistry

Computational Inorganic and Bioinorganic Chemistry
Author : Edward I. Solomon,Robert A. Scott,R. Bruce King
Publisher : John Wiley & Sons
Release Date : 2013-02-19
Category : Science
Total pages :616
GET BOOK

Over the past several decades there have been major advances in ourability to computationally evaluate the electronic structure ofinorganic molecules, particularly transition metal systems. Thisadvancement is due to the Moore’s Law increase in computingpower as well as the impact of density functional theory (DFT) andits implementation in commercial and freeware programs for quantumchemical calculations. Improved pure and hybrid density functionalsare allowing DFT calculations with accuracy comparable tohigh-level Hartree-Fock treatments, and the results of thesecalculations can now be evaluated by experiment. When calculations are correlated to, and supported by,experimental data they can provide fundamental insight intoelectronic structure and its contributions to physical propertiesand chemical reactivity. This interplay continues to expand andcontributes to both improved value of experimental results andimproved accuracy of computational predictions. The purpose of this EIC Book is to provide state-of-the-artpresentations of quantum mechanical and related methods and theirapplications, written by many of the leaders in the field. Part 1of this volume focuses on methods, their background andimplementation, and their use in describing bonding properties,energies, transition states and spectroscopic features. Part 2focuses on applications in bioinorganic chemistry and Part 3discusses inorganic chemistry, where electronic structurecalculations have already had a major impact. This addition to theEIC Book series is of significant value to both experimentalistsand theoreticians, and we anticipate that it will stimulate bothfurther development of the methodology and its applications in themany interdisciplinary fields that comprise modern inorganic andbioinorganic chemistry. This volume is also available as part of Encyclopedia ofInorganic Chemistry, 5 Volume Set. This set combines all volumes published as EIC Books from 2007to 2010, representing areas of key developments in the field ofinorganic chemistry published in the Encyclopedia of InorganicChemistry. ahref="http://eu.wiley.com/WileyCDA/WileyTitle/productCd-1119994284.html"Findout more/a.

Iron Metabolism

Iron Metabolism
Author : Robert Crichton
Publisher : John Wiley & Sons
Release Date : 2016-05-31
Category : Medical
Total pages :576
GET BOOK

Iron is indispensable for the growth, development and well-being of almost all living organisms. Biological systems from bacteria, fungi and plants to humans have evolved systems for the uptake, utilisation, storage and homeostasis of iron. Its importance for microbial growth makes its uptake systems a natural target for pathogenic microorganisms and parasites. Uniquely, humans suffer from both iron deficiency and iron overload, while the capacity of iron to generate highly reactive free radicals, causing oxidative stress, is associated with a wide range of human pathologies, including many neurodegenerative diseases. Whereas some essential metal ions like copper and zinc are closely linked with iron metabolism, toxic metals like aluminium and cadmium can interfere with iron metabolism. Finally, iron metabolism and homeostasis are key targets for the development of new drugs for human health. The 4th edition of Iron Metabolism is written in a lively style by one of the leaders in the field, presented in colour and covers the latest discoveries in this exciting area. It will be essential reading for researchers and students in biochemistry, molecular biology, microbiology, cell biology, nutrition and medical sciences. Other interested groups include biological inorganic chemists with an interest in iron metabolism, health professionals with an interest in diseases of iron metabolism, or of diseases in which iron uptake systems are involved (eg. microbial and fungal infections, cancer, neurodegenerative disorders), and researchers in the pharmaceutical industry interested in developing novel drugs targeting iron metabolism/homeostasis.

New Directions in the Modeling of Organometallic Reactions

New Directions in the Modeling of Organometallic Reactions
Author : Agustí Lledós
Publisher : Springer Nature
Release Date : 2020
Category :
Total pages :129
GET BOOK

Electrons, Atoms, and Molecules in Inorganic Chemistry

Electrons, Atoms, and Molecules in Inorganic Chemistry
Author : Joseph J. Stephanos,Anthony W. Addison
Publisher : Academic Press
Release Date : 2017-06-01
Category : Science
Total pages :762
GET BOOK

Electrons, Atoms, and Molecules in Inorganic Chemistry: A Worked Examples Approach builds from fundamental units into molecules, to provide the reader with a full understanding of inorganic chemistry concepts through worked examples and full color illustrations. The book uniquely discusses failures as well as research success stories. Worked problems include a variety of types of chemical and physical data, illustrating the interdependence of issues. This text contains a bibliography providing access to important review articles and papers of relevance, as well as summaries of leading articles and reviews at the end of each chapter so interested readers can readily consult the original literature. Suitable as a professional reference for researchers in a variety of fields, as well as course use and self-study. The book offers valuable information to fill an important gap in the field. Incorporates questions and answers to assist readers in understanding a variety of problem types Includes detailed explanations and developed practical approaches for solving real chemical problems Includes a range of example levels, from classic and simple for basic concepts to complex questions for more sophisticated topics Covers the full range of topics in inorganic chemistry: electrons and wave-particle duality, electrons in atoms, chemical binding, molecular symmetry, theories of bonding, valence bond theory, VSEPR theory, orbital hybridization, molecular orbital theory, crystal field theory, ligand field theory, electronic spectroscopy, vibrational and rotational spectroscopy

Inorganic Chemical Biology

Inorganic Chemical Biology
Author : Gilles Gasser
Publisher : John Wiley & Sons
Release Date : 2014-04-14
Category : Science
Total pages :432
GET BOOK

Understanding, identifying and influencing the biologicalsystems are the primary objectives of chemical biology. From this perspective, metal complexes havealways been of great assistance to chemical biologists, for example, in structural identificationand purification of essential biomolecules, for visualizing cellular organelles or to inhibitspecific enzymes. This inorganic side of chemical biology, which continues to receive considerableattention, is referred to as inorganic chemical biology. Inorganic Chemical Biology: Principles, Techniques andApplications provides a comprehensive overview of the current and emerging role of metal complexes inchemical biology. Throughout all of the chapters there is a strong emphasis on fundamentaltheoretical chemistry and experiments that have been carried out in living cells or organisms. Outlooksfor the future applications of metal complexes in chemical biology are also discussed. Topics covered include: • Metal complexes as tools for structural biology • IMAC, AAS, XRF and MS as detection techniques for metals inchemical biology • Cell and organism imaging and probing DNA using metal andmetal carbonyl complexes • Detection of metal ions, anions and small molecules usingmetal complexes • Photo-release of metal ions in living cells • Metal complexes as enzyme inhibitors and catalysts inliving cells Written by a team of international experts, Inorganic ChemicalBiology: Principles, Techniques and Applications is a must-have for bioinorganic,bioorganometallic and medicinal chemists as well as chemical biologists working in both academia and industry.

Biological Inorganic Chemistry

Biological Inorganic Chemistry
Author : Robert R. Crichton
Publisher : Elsevier
Release Date : 2007-12-11
Category : Science
Total pages :381
GET BOOK

The importance of metals in biology, the environment and medicine has become increasingly evident over the last twenty five years. The study of the multiple roles of metal ions in biological systems, the rapidly expanding interface between inorganic chemistry and biology constitutes the subject called Biological Inorganic Chemistry. The present text, written by a biochemist, with a long career experience in the field (particularly iron and copper) presents an introduction to this exciting and dynamic field. The book begins with introductory chapters, which together constitute an overview of the concepts, both chemical and biological, which are required to equip the reader for the detailed analysis which follows. Pathways of metal assimilation, storage and transport, as well as metal homeostasis are dealt with next. Thereafter, individual chapters discuss the roles of sodium and potassium, magnesium, calcium, zinc, iron, copper, nickel and cobalt, manganese, and finally molybdenum, vanadium, tungsten and chromium. The final three chapters provide a tantalising view of the roles of metals in brain function, biomineralization and a brief illustration of their importance in both medicine and the environment. Relaxed and agreeable writing style. The reader will not only fiind the book easy to read, the fascinating anecdotes and footnotes will give him pegs to hang important ideas on. Written by a biochemist. Will enable the reader to more readily grasp the biological and clinical relevance of the subject. Many colour illustrations. Enables easier visualization of molecular mechanisms Written by a single author. Ensures homgeneity of style and effective cross referencing between chapters

Contemporary Chemistry: A Practical Approach

Contemporary Chemistry: A Practical Approach
Author : Leonard Saland
Publisher : Walch Publishing
Release Date : 1993
Category : Education
Total pages :170
GET BOOK

This comprehensive guide gives you lesson plans, activities, and tests for two sequential, semester-long chemistry courses. It is designed to work with our student book Contemporary Chemistry. Each lesson plan features: a DO NOW section to engage students as soon as they get to class instructional objectives an aimfor that class period a motivational application questions or demonstrations to help students draw valid conclusions homework assignments You also get term calendars, weekly tests, and complete answer keys.

Applications of Density Functional Theory to Biological and Bioinorganic Chemistry

Applications of Density Functional Theory to Biological and Bioinorganic Chemistry
Author : Mihai V. Putz,D Michael P Mingos
Publisher : Springer
Release Date : 2013-02-01
Category : Science
Total pages :236
GET BOOK

The series Structure and Bonding publishes critical reviews on topics of research concerned with chemical structure and bonding. The scope of the series spans the entire Periodic Table and addresses structure and bonding issues associated with all of the elements. It also focuses attention on new and developing areas of modern structural and theoretical chemistry such as nanostructures, molecular electronics, designed molecular solids, surfaces, metal clusters and supramolecular structures. Physical and spectroscopic techniques used to determine, examine and model structures fall within the purview of Structure and Bonding to the extent that the focus is on the scientific results obtained and not on specialist information concerning the techniques themselves. Issues associated with the development of bonding models and generalizations that illuminate the reactivity pathways and rates of chemical processes are also relevant. The individual volumes in the series are thematic. The goal of each volume is to give the reader, whether at a university or in industry, a comprehensive overview of an area where new insights are emerging that are of interest to a larger scientific audience. Thus each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years should be presented using selected examples to illustrate the principles discussed. A description of the physical basis of the experimental techniques that have been used to provide the primary data may also be appropriate, if it has not been covered in detail elsewhere. The coverage need not be exhaustive in data, but should rather be conceptual, concentrating on the new principles being developed that will allow the reader, who is not a specialist in the area covered, to understand the data presented. Discussion of possible future research directions in the area is welcomed. Review articles for the individual volumes are invited by the volume editors. Readership: research scientists at universities or in industry, graduate students Special offer For all customers who have a standing order to the print version of Structure and Bonding, we offer free access to the electronic volumes of the Series published in the current year via SpringerLink.

The FASEB Journal

The FASEB Journal
Author : Anonim
Publisher : Unknown
Release Date : 1991
Category : Biology
Total pages :129
GET BOOK

Techniques in Inorganic Chemistry

Techniques in Inorganic Chemistry
Author : Jr., John P. Fackler,Larry R. Falvello
Publisher : CRC Press
Release Date : 2010-07-16
Category : Science
Total pages :219
GET BOOK

Inorganic chemistry continues to generate much current interest due to its array of applications, ranging from materials to biology and medicine. Techniques in Inorganic Chemistry assembles a collection of articles from international experts who describe modern methods used by research students and chemists for studying the properties and structure

Inorganic Aspects of Biological and Organic Chemistry

Inorganic Aspects of Biological and Organic Chemistry
Author : Robert Hanzlik
Publisher : Elsevier
Release Date : 2012-12-02
Category : Science
Total pages :420
GET BOOK

Inorganic Aspects of Biological and Organic Chemistry investigates the inorganic aspects of biological and organic chemistry. Topics include the inorganic chemistry of group Ia and IIa metals; complexes of Ia and IIa cations in organic and biological chemistry; atomic structure and structure-activity correlations; and bonding in ligands and metal complexes. Ligand exchange reactions and factors in complex stability are also discussed. Comprised of 12 chapters, this book begins with an overview of some of the important roles of metals in biological and organic chemistry, followed by an analysis of the inorganic chemistry of group Ia and IIa metals. Complexes of Ia and IIa cations in organic and biological chemistry are then described, together with atomic structure and structure-activity correlations. Subsequent chapters deal with bonding in ligands and metal complexes; ligand exchange reactions and factors in complex stability; redox potentials and processes; and the influence of metal ions on equilibria. The book also considers catalysis by metal ions, metal complexes, and metalloenzymes before concluding with a chapter that examines the reactions of ligands in organometallic complexes. This monograph is written for teachers, students, and practitioners of organic, biological, and inorganic chemistry.

The Chemistry and Biology of Nitroxyl (HNO)

The Chemistry and Biology of Nitroxyl (HNO)
Author : Fabio Doctorovich,Patrick J. Farmer,Marcelo A. Marti
Publisher : Elsevier
Release Date : 2016-09-01
Category : Science
Total pages :424
GET BOOK

The Chemistry and Biology of Nitroxyl (HNO) provides first-of-its-kind coverage of the intriguing biologically active molecule called nitroxyl, or azanone per IUPAC nomenclature, which has been traditionally elusive due to its intrinsically high reactivity. This useful resource provides the scientific basis to understand the chemistry, biology, and technical aspects needed to deal with HNO. Building on two decades of nitric oxide and nitroxyl research, the editors and authors have created an indispensable guide for investigators across a wide variety of areas of chemistry (inorganic, organic, organometallic, biochemistry, physical, and analytical); biology (molecular, cellular, physiological, and enzymology); pharmacy; and medicine. This book begins by exploring the unique molecule’s structure and reactivity, including important reactions with small molecules, thiols, porphyrins, and key proteins, before discussing chemical and biological sources of nitroxyl. Advanced chapters discuss methods for both trapping and detecting nitroxyl by spectroscopy, electrochemistry, and fluorescent inorganic cellular probing. Expanding on the compound’s foundational chemistry, this book then explores its molecular physiology to offer insight into its biological implications, pharmacological effects, and practical issues. Presents the first book on HNO (nitroxyl or azanone), an increasingly important molecule in biochemistry and pharmaceutical research Provides a valuable coverage of HNO’s chemical structure and significant reactions, including practical guidance on working with this highly reactive molecule Contains high quality content from recognized experts in both industry and academia