November 30, 2020

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Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
Author : Arthur J. Atkinson
Publisher : Academic Press
Release Date : 2012
Category : Medical
Total pages :626
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Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. * Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. * Offers an expanded regulatory section that addresses US and international issues and guidelines. * Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. * Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III.

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
Author : Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
Publisher : Elsevier
Release Date : 2011-04-28
Category : Medical
Total pages :568
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This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
Author : Arthur J. Atkinson, Jr.,Charles E. Daniels,Robert Dedrick,Charles V. Grudzinskas,Sanford P. Markey
Publisher : Gulf Professional Publishing
Release Date : 2001
Category : Medical
Total pages :460
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The rate of introduction of new pharmaceutical products has increased rapidly over the past decade, and details learned about a particular drug become obsolete as it is replaced by newer agents. For this reason, this book focuses on the principles that underlie the clinical use and contemporary development of pharmaceuticals. The coverage of these principles that is presented in this book will be of particular benefit to individuals engaged either in the teaching or study of sound therapeutic technique or in the investigation of pharmacological agents. Key Features * Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy * Unusual cohesiveness of presentation that stems from author participation in an ongoing popular NIH course * Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study * Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
Author : Arthur J. Atkinson, Jr.
Publisher : Academic Press
Release Date : 2007
Category : Medical
Total pages :545
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Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. Offers an expanded regulatory section that addresses US and international issues and guidelines. Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III.

Atkinson's Principles of Clinical Pharmacology

Atkinson's Principles of Clinical Pharmacology
Author : Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson, Jr.
Publisher : Academic Press
Release Date : 2021-03-15
Category : Medical
Total pages :652
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Atkinson's Principles of Clinical Pharmacology, Fourth Edition is the essential reference covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. Presents the essential knowledge for effective practice of Clinical Pharmacology Includes a new chapter and extended discussion on the role of Personalized and Precision Medicine in Clinical Pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also further discussion on "Phase 0" studies (microdosing) and PBPK

Melmon and Morrelli's Clinical Pharmacology

Melmon and Morrelli's Clinical Pharmacology
Author : Kenneth L. Melmon,Howard F. Morrelli,David F. Nierenberg
Publisher : McGraw Hill Professional
Release Date : 2000
Category : Medical
Total pages :1433
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Perfect for the student, primary care practitioner, and pharmacist who needs both basic and clinical information to apply therapeutics A new overview chapter--plus practical steps required for optimal therapeutic decisions Coverage of newly emerging advances in therapeutics A new look at cost/benefit analysis of therapy Increased emphasis on drug interactions, and much more

Small Animal Clinical Pharmacology

Small Animal Clinical Pharmacology
Author : Jill E. Maddison,Stephen W. Page,David Church (BVSc.)
Publisher : Elsevier Health Sciences
Release Date : 2008
Category : Medical
Total pages :589
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Small Animal Clinical Pharmacology is a practical, clinically-oriented pharmacology text designed to provide the veterinary student and practitioner with all the relevant information needed when designing drug treatment regimens for pets in small animal veterinary practice. Comprehensively updated and revised, the second edition of this core text covers essential new information on drugs used in the management of a range of presenting conditions including heart disease and cardiac arrhythmias. For the second edition new authors, superb new illustrations and a second colour have all been introduced. With its unique approach combining a thorough understanding of the pharmacological action of drugs with a basic understanding of the relevant physiology and pathophysiology of systems and tissues affected, Small Animal Clinical Pharmacology continues to be an indispensable book for all veterinary students and practitioners. Organised by drug class in a uniform and detailed structure which means it is easy to locate key information on dose rates, routes of administration, drug interactions and special considerations at a glance Key chapters based around treatment of disorders of particular body systems, eg cardiovascular and thyroid disorders Essential introductory chapters covering pharmacokinetics, general pharmacological principles and adverse reactions for a thorough basic grounding in the subject All authors are experienced clinicians and recognised experts in their field who bring a down to earth and practical approach to the text

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
Author : Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
Publisher : Elsevier
Release Date : 2011-04-28
Category : Medical
Total pages :568
GET BOOK

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Anesthetic Pharmacology

Anesthetic Pharmacology
Author : Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publisher : Cambridge University Press
Release Date : 2011-03-10
Category : Medical
Total pages :129
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In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Clinical Pharmacology and Therapeutics

Clinical Pharmacology and Therapeutics
Author : Gerard A. McKay,Matthew R. Walters,Neil D. Ritchie
Publisher : John Wiley & Sons
Release Date : 2020-11-09
Category : Medical
Total pages :320
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A must-have companion for medical students and junior doctors for almost four decades, Lecture Notes: Clinical Pharmacology and Therapeutics provides concise yet thorough coverage of the principles of clinical pharmacology, the major characteristics of therapeutics, and the practical aspects of prescribing drugs to alleviate symptoms and to treat disease. Whether you are preparing for examinations or prescribing to patients, the tenth edition offers readers current and authoritative insight into the essential practical and clinical knowledge. Logically organised chapters allow for rapid location of key information, while examples of commonly encountered scenarios illustrate how and when to use drugs in clinical situations. Throughout the text, practice questions, prescribing guidelines, and self-assessment tests clarify and reinforce the principles that inform appropriate clinical decision-making. Presents an up-to-date review of drug use across all major clinical disciplines Offers a timely overview of clinical drug trials and development Provides new clinical scenarios to relate chapter content to real-life application Contains colour-coded “Key Points” and “Prescribing Points” to highlight important information Includes chapter introductions and summaries, and numerous figures, tables, and colour illustrations Lecture Notes: Clinical Pharmacology and Therapeutics, Tenth Edition, is an essential resource for medical students, junior doctors, and other prescribers looking for an up-to-date reference on pharmacological principles, prescribing, and therapeutics.

Clinical Pharmacology

Clinical Pharmacology
Author : Morris J. Brown,Pankaj Sharma,Peter N. Bennett
Publisher : Elsevier Health Sciences
Release Date : 2012-07-30
Category : Medical
Total pages :640
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A thorough knowledge of pharmacological and therapeutic principles is vital if drugs are to be used safely and effectively for increasingly informed patients. Those who clearly understand how drugs get into the body, how they produce their effects, what happens to them in the body, and how evidence of their therapeutic effect is assessed, will choose drugs more skilfully, and use them more safely and successfully than those who do not. Now in a fully revised 11th edition, Clinical Pharmacology is essential reading for undergraduate medical students, junior doctors and anyone concerned with evidence-based drug therapy. Introductory first three sections cover general principle of clinical pharmacology; five subsequent sections cover drug treatment of disease organised by body system. Retains approachable style set by the original author, Professor Laurence. Emphasis throughout is on evidence-based and safe drug prescribing. Indian Advisory Board will ensure content reflects the needs of the devloping world.

Clinical Pharmacology

Clinical Pharmacology
Author : Cynthia Webster
Publisher : Teton NewMedia
Release Date : 2001-03
Category : Medical
Total pages :150
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Presented in a highly visual style, this book offers an introduction to clinically relevant pharmacologic agents used in small and large animal practice. It includes an overview of key concepts in pharmacology including basic principles of pharmacodynamics, physiological uptake and nervous system perception. Various types of drugs are discussed, including: tranqulizers, sedatives and opiods. Pharmacologic effects, side effects, drug interactions and species differences are illustrated with emphasis on figures, charts and diagrams. Over 100 study questions test retention and comprehension. This "quick look" is well-presented, easy to follow, very concise and should be instrumental in developing a rudimentary understanding of pharmacological principles in animal medicine.

Clinical Pharmacology

Clinical Pharmacology
Author : Kenneth Lloyd Melmon,Howard F. Morrelli
Publisher : Unknown
Release Date : 1978
Category : Pharmacology
Total pages :1146
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Principles of Pharmacology

Principles of Pharmacology
Author : David E. Golan
Publisher : Lippincott Williams & Wilkins
Release Date : 2008
Category : Medical
Total pages :985
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This primary textbook for a first course in pharmacology offers an integrated, systems-based, and mechanism-based approach to understanding drug therapy. Each chapter focuses on a target organ system, begins with a clinical case, and incorporates cell biology, biochemistry, physiology, and pathophysiology to explain how and why different drug classes are effective for diseases in that organ system. Over 400 two-color illustrations show molecular, cellular, biochemical, and pathophysiologic processes underlying diseases and depict targets of drug therapy. Each Second Edition chapter includes a drug summary table presenting mechanism, clinical applications, adverse effects, contraindications, and therapeutic considerations. New chapters explain how drugs produce adverse effects and describe the life cycle of drug development. The fully searchable online text and an image bank are available on thePoint.

Oxford Textbook of Oncology

Oxford Textbook of Oncology
Author : David J. Kerr,Daniel G. Haller,Cornelis J. H. van de Velde,Michael Baumann
Publisher : Oxford University Press
Release Date : 2016-01-28
Category : Medical
Total pages :832
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Now in paperback, the Oxford Textbook of Oncology reflects current best practice in the multidisciplinary management of cancer, written and edited by internationally recognised leaders in the field. Structured in six sections, the book provides an accessible scientific basis to the key topics of oncology, examining how cancer cells grow and function, as well as discussing the aetiology of cancer, and the general principles governing modern approaches to oncology treatment. The book examines the challenges presented by the treatment of cancer on a larger scale within population groups, and the importance of recognising and supporting the needs of individual patients, both during and after treatment. A series of disease-oriented, case-based chapters, ranging from acute leukaemia to colon cancer, highlight the various approaches available for managing the cancer patient, including the translational application of cancer science in order to personalise treatment. The advice imparted in these cases has relevance worldwide, and reflects a modern approach to cancer care. The Oxford Textbook of Oncology provides a comprehensive account of the multiple aspects of best practice in the discipline, making it an indispensable resource for oncologists of all grades and subspecialty interests.