November 27, 2020

Download Ebook Free Protein Biosynthesis Interference In Disease

Protein Biosynthesis Interference in Disease

Protein Biosynthesis Interference in Disease
Author : Elena L. Paley
Publisher : Academic Press
Release Date : 2020-10-08
Category : Science
Total pages :296
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Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms of action, and influence over disease processes. This book examines the role of protein biosynthesis interference in Alzheimer’s and other neurodegenerative conditions, cancer and inflammatory disorders, with specific attention paid to the biochemical dynamics of tryptamine, biogenic amines and aminoacyl-tRNA synthetases in these pathologies. Methods of regulating protein translation and interference mechanisms, including gene therapy, are presented, empowering biochemists, molecular biologists, disease researchers, and health professionals to understand the underlying factors of protein disease and improve patient outcomes. Enables biochemists, molecular biologists and disease researchers to advance disease prevention, laboratory testing, and treatment pathways for protein biosynthesis interference related disorders Examines the biochemical and molecular basis of protein biosynthesis interference in neurodegenerative disorders, cancer and inflammatory conditions, among other diseases Analyzes tryptamine, biogenic amines, and aminoacyl-tRNA synthetases dynamics in protein translation and possible treatment pathways regulating protein biosynthesis

Viruses and Human Disease

Viruses and Human Disease
Author : Ellen G. Strauss,James H. Strauss
Publisher : Elsevier
Release Date : 2007-09-21
Category : Science
Total pages :480
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Completely revised and updated, the new edition of this groundbreaking text integrates basic virology with pathophysiological conditions to examine the connection between virology and human disease. Most virology textbooks focus on the molecular biology involved without adequate reference to physiology. This text focuses on viruses that infect humans, domestic animals and vertebrates and is based on extensive course notes from James Strauss’ virology class at the California Institute of Technology taught for over 30 years. Expertly depicting in color the molecular structure and replication of each virus, it provides an excellent overview for students and professionals interested in viruses as agents of human disease. Includes over 30% new material - virtually all of the figures and tables have been redrawn to include the latest information and the text has been extensively rewritten to include the most up-to-date information Includes a new chapter on emerging and reemerging viral diseases such as avian flu, SARS, the spread of West Nile virus across America, and the continuing spread of Nipah virus in Southeast Asia Further reading sections at the end of each chapter make it easy find key references World maps depicting the current distribution of existing and newly emerging viruses are also incorporated into the text

Cell and Molecular Biology

Cell and Molecular Biology
Author : Gerald Karp
Publisher : John Wiley & Sons
Release Date : 2009-10-19
Category : Science
Total pages :832
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Karp continues to help biologists make important connections between key concepts and experimentation. The sixth edition explores core concepts in considerable depth and presents experimental detail when it helps to explain and reinforce the concepts. The majority of discussions have been modified to reflect the latest changes in the field. The book also builds on its strong illustration program by opening each chapter with “VIP” art that serves as a visual summary for the chapter. Over 60 new micrographs and computer-derived images have been added to enhance the material. Biologists benefit from these changes as they build their skills in making the connection.

Interferon Bibliography from MEDLARS.

Interferon Bibliography from MEDLARS.
Author : Anonim
Publisher : Unknown
Release Date : 1976
Category : Interferon
Total pages :129
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Molecules, Cells, and Disease

Molecules, Cells, and Disease
Author : J.L. VanLancker
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :311
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In tracing their origin and their fate, the beginning and the end of their environment, humans have often been guided by curiosity. Such concern has helped man to discover, among other things, the structure of the universe from star to atom and the evolution of life from unicellular organism to human being. The study of disease is unique. Although it may have been in spired by the curiosity of a few, it has always been the concern of all, because preventing or curing disease has meant survival not only of individuals, but of entire nations, not only of humans, but of fellow living creatures. If greed, force, religion, and language have been major causes of wars, diseases, more than arms, have often decided the outcome of battles and thereby have woven the pattern of history. For millennia, a large fraction of the human race believed that disease expressed the wrath of God(s) against individuals or societies. Therefore, only priests or priestesses, kings, and queens were endowed with the power of healing. In the West, Hippocrates is credited for exorcising this concept of disease and for objectively describing and cataloguing them. The contributions of Greek physicians to Western medicine made possible more accurate diagnoses and prognoses.

RNA Interference Technology

RNA Interference Technology
Author : Krishnarao Appasani
Publisher : Cambridge University Press
Release Date : 2005-01-17
Category : Science
Total pages :129
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RNA Interference (RNAi) technology has rapidly become one of the key methods used in functional genomics. RNAi is used to block the expression of genes and create phenotypes that can potentially yield clues about the function of these genes. In the postgenomic era, the elucidation of the physiological function of genes has become the rate-limiting step in the quest to develop 'gene-based drugs' and RNAi could potentially play a pivotal role in the validation of such novel drugs. In this overview, the basic concepts and applications of RNAi biology are discussed. Leading experts from both academia and industry have contributed to this invaluable reference. The volume is forwarded by Andrew Fire, one of the winners of the 2006 Nobel Prize for the discovery of RNA Interference.

Infectious Diseases in the Female Patient

Infectious Diseases in the Female Patient
Author : Rudolph P. Galask,Bryan Larsen
Publisher : Springer Science & Business Media
Release Date : 2012-12-06
Category : Medical
Total pages :264
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In obstetrics and gynecology, as in other medical disciplines, great satisfaction comes from doing, but a greater satisfaction comes from knowing. The desire to know raises clinical practice to its highest level. This principle guided us in determining the objectives for this volume. Several standard textbooks of obstetrics and gynecology include information about infectious problems. Infectious Diseases in the Female Patient is unique in that it emphasizes primarily the basic science as pects of infections in obstetrics and gynecology. Although providing a practitioner's handbook was not our goal, the reader nevertheless will find discussions of the management of infections in the female pa tient. The continued growth of knowledge about infectious disease en countered in obstetrics and gynecology has come from many sources: bacteriology, virology, genetics, immunology, biochemistry, physiol ogy, and pharmacology. Insights from all these disciplines contribute to the conceptual framework of this volume. Many of the authors who contributed to this text are leaders in their respective areas of research and bring to the book a diversity of ex pertise and experience. Controversial issues are developed in a bal anced fashion, and, in most cases, opposing views are discussed. Since medical texts usually are read piece-meal rather than cover to cover, we have allowed some overlap between chapters. The slight degree of redundancy allows each chapter to stand on its own, so that the reader may obtain the necessary information from a single chapter.

Veterinary Microbiology and Microbial Disease

Veterinary Microbiology and Microbial Disease
Author : P. J. Quinn,B. K. Markey,F. C. Leonard,P. Hartigan,S. Fanning,E. S. Fitzpatrick
Publisher : John Wiley & Sons
Release Date : 2011-10-07
Category : Medical
Total pages :400
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Microbiology is one of the core subjects for veterinary students,and since its first publication in 2002, Veterinary Microbiologyand Microbial Disease has become an essential text for students ofveterinary medicine. Fully revised and expanded, this new editionupdates the subject for pre-clinical and clinical veterinarystudents in a comprehensive manner. Individual sections deal withbacteriology, mycology and virology. Written by an academic teamwith many years of teaching experience, the book provides concisedescriptions of groups of microorganisms and the diseases whichthey cause. Microbial pathogens are discussed in separate chapterswhich provide information on the more important features of eachmicroorganism and its role in the pathogenesis of diseases ofanimals. The international and public health significance of thesepathogens are reviewed comprehensively. The final section isconcerned with the host and is organized according to the bodysystem affected. Tables, boxes and flow diagrams provide information in an easilyassimilated format. This edition contains new chapters on moleculardiagnostics and on infectious conditions of the skin,cardiovascular system, urinary tract and musculoskeletal system.Many new colour diagrams are incorporated into this edition andeach chapter has been updated. Key features of this edition: Twelve new chapters included Numerous new illustrations Each chapter has been updated Completely re-designed in full colour Fulfils the needs of veterinary students and academics inveterinary microbiology Companion website with figures from the book as Powerpoints forviewing or downloading by chapter: ahref="http://www.wiley.com/go/quinn/veterinarymicrobiology"www.wiley.com/go/quinn/veterinarymicrobiology/a Veterinary Microbiology and Microbial Disease remainsindispensable for all those studying and teaching this essentialcomponent of the veterinary curriculum.

Retinal Pharmacotherapy E-Book

Retinal Pharmacotherapy E-Book
Author : Quan Dong Nguyen,Eduardo Buchele Rodrigues,Michel Eid Farah,William F. Mieler
Publisher : Elsevier Health Sciences
Release Date : 2010-02-26
Category : Medical
Total pages :408
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Retinal Pharmacotherapy is the first comprehensive book devoted to pharmacologic agents and their rationale and mechanisms of action in selected retinal and uveitic diseases. Drs. Quan Dong Nguyen, Eduardo Buchele Rodrigues, Michel Eid Farah, and William F. Mieler lead an international team of expert contributors to present up-to-date knowledge of new drugs on the market, the science behind the drugs, evidence of how the drugs work, and the reasons why they are effective or not. This user-friendly, all-in-one reference provides you with easy access to practical information on the effective and appropriate use of pharmacologic agents in the management of retinal diseases. Covers all new and existing retinal drugs to keep you current in this expanding area of the treatment of retinal diseases. Discusses the background behind retinal drugs and the various pathways of how they work so you can make thoroughly informed clinical decisions. Presents 400 color photographs and line drawings that illustrate disease appearance before and after treatment and clarify difficult key concepts. Features contributors from Europe, North America, South America, the Middle East, Asia, and Australia for an international approach. Identifies and emphasizes key points clearly in each chapter to improve comprehension and make finding information easier.

Active Homologous Interference Between Strains of Newcastle Disease Virus

Active Homologous Interference Between Strains of Newcastle Disease Virus
Author : Terrence Duane Jones
Publisher : Unknown
Release Date : 1974
Category :
Total pages :232
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Gene Therapy for Renal Diseases and Transplantation

Gene Therapy for Renal Diseases and Transplantation
Author : Ariela Benigni,Giuseppe Remuzzi
Publisher : Karger Medical and Scientific Publishers
Release Date : 2008-01-01
Category : Medical
Total pages :167
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Initially conceived as a strategy to remedy inherited genetic disorders, gene therapy has been successfully applied in the last decade to ameliorate the renal function compromised by progressive renal diseases and to prevent kidney allograft rejection in experimental animals. In the present book, world-renowned experts are presenting new insights into viral and non-viral systems used to effect gene delivery, one chapter being dedicated to the new field of RNA interference (RNAi). This latter method may be successfully used in renal ischemia-reperfusion injury, trauma and transplantation. In the near future, gene therapy might also prove to be a new strategy to target molecules involved in tissue damage and inflammation processes that underlie ARF. So far, gene transfer has been successfully applied in experimental glomerulonephritis and interstitial fibrosis, and studies in larger animals are keenly awaited. Also covered are issues related to transplantation, which is the therapy of choice in many end-stage organ failures. Transfer of genes whose protein products have immunomodulatory properties have proven beneficial in treating acute and chronic graft rejection, one of the problems not satisfactorily solved by current anti-rejection drugs. Gene therapy thus may become a reality in clinical transplantation once its efficacy in larger animals has been demonstrated. Last but not least, a possible benefit of targeted gene therapy in renal cancer or HIV-associated nephropathy is explored. Covering a wide spectrum of topics, this publication provides a valuable overview of current developments and issues.

Mechanisms of Disease

Mechanisms of Disease
Author : Ruy Pérez-Tamayo
Publisher : Unknown
Release Date : 1985
Category : Pathology
Total pages :652
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Neuromuscular Diseases

Neuromuscular Diseases
Author : Michael Swash,Martin S. Schwartz
Publisher : Springer Science & Business Media
Release Date : 2013-03-14
Category : Medical
Total pages :541
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Nine years have elapsed since the second edition of this book was published. In this time the principal advances in neuromuscular diseases have been in the application of molecular genetics to understanding the aetiology and pathogenesis of this group of disorders. As a result many previously unrecognised disorders have been charac terised. Some clinical syndromes, such as the limb girdle dystrophies, have become better defined. In many such instances the new genetic information has led to major advances in knowledge of the biology of cell structures, for example, the membrane structural and channel proteins. The clinical syndromes themselves, and their patho logical and electrophysiological characteristics, however, remain as important as ever, since they constitute the clinical problem itself and, indeed, the database from which all other concepts emerge. Knowledge of the pathogenesis, genetics, and molecular biology of neuromuscular disorders is essential both in developing and applying new therapies and preventive measures, and in formulating genetic and prognostic advice. However, this informa tion does not necessarily always define clinically useful syndromes. Myotonia, for example, is an electrophysiological finding in some syndromes in which it is un detectable by clinical examination, although the phenomenon itself was originally defined as a clinical entity. The limb girdle muscular dystrophy syndromes can be defined by severity, distribution of weakness, age of onset, sex distribution and other characteristics and many of these can be better understood by study of the under lying defect in cell structural proteins.

Aromatic Amino Acid Hydroxylases and Mental Disease

Aromatic Amino Acid Hydroxylases and Mental Disease
Author : Moussa B. H. Youdim
Publisher : John Wiley & Sons
Release Date : 1979
Category : Acides aminés - Métabolisme
Total pages :390
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Pathophysiology for the Health Professions - E- Book

Pathophysiology for the Health Professions - E- Book
Author : Barbara E. Gould,Ruthanna Dyer
Publisher : Elsevier Health Sciences
Release Date : 2014-04-11
Category : Medical
Total pages :736
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A concise, easy-to-understand introduction to the fundamentals, Pathophysiology for the Health Professions, 4th Edition helps you learn to identify disease processes and disorders. Authors Barbara Gould and Ruthanna Dyer continue the tradition of a text known for its readability and vivid, full-color illustrations, updated with the latest research and clinical advances. Unique Challenge, Think About, and Emergency Treatment features help in applying the material to real-life situations. No matter which area in the healthcare field you may enter, this book provides essential preparation for conditions encountered in clinical practice. Concise and readable approach includes the information students need without overwhelming them, even if they have a limited scientific background. Unique Challenge feature asks "What can go wrong with this structure or system?" as a way to help students facilitate progress by using previously learned knowledge. Unique Think About boxes help with self-evaluation, test preparation, and review. Unique Emergency Treatment boxes list basic emergency measures; these can be modified to fit specific professions, established protocols, or practice settings. Research boxes discuss new developments, problem areas of pathophysiology, and complications associated with research. Warning Signs boxes summarize conditions that may develop in patients. Diagnostic tests and treatments are included for each of the major disorders. Case studies in each chapter provide a basis for discussion or can be used as an assignment. Study questions offer a self-assessment on the material in each chapter. Ready References in the appendix provide a quick lookup for anatomic terms, conversion tables, abbreviations and acronyms, diagnostic studies and tests, and more. A companion Evolve website includes web links, learning activities, content updates, and more. New content on the causes and trends related to disease, new drugs, technology, and treatment. Coverage of obesity and its complications, including an in-depth discussion of metabolic syndrome. Multiple disorder syndromes in the aged client. DNA, genetics and the Human Genome Project with current research on protein pathways in health (proteomics) and the implications for drug treatment and disease causation. Coverage of autism. Updated content on the H1N1 virus and communicable diseases; HIV, cancer causation, and immunology; and substance abuse to reflect common practices in the use of illicit (street) drugs as well as abuse of prescription medications. Case studies revised to emphasize chronic diseases, prevention, and acute care, and to apply to a wider range of health professions. Appendices reorganized for improved reference and lookup.