June 15, 2021

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Spinal Interneurons

Spinal Interneurons
Author : Lyandysha Zholudeva,Michael Lane
Publisher : Academic Press
Release Date : 2021-06-15
Category : Medical
Total pages :300
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Spinal Interneurons: Plasticity after Spinal Cord Injury provides neuroscientists, clinicians and trainees a reference book exclusively concentrating on spinal interneurons and the techniques and experiments employed to identify and study these cells as part of normal, diseased and injured neural circuits. In addition, the book highlights the therapeutic potential of these cells by presenting relevant pre-clinical and clinical work that has been performed. The book's focus on the latest in therapeutic strategies for targeting spinal interneurons, considerations for the development and use of treatments, and how such treatments work make this a comprehensive source of information. Provides a comprehensive overview of the techniques used to identify, characterize and classify spinal interneurons and their role in neural circuits Presents an in-depth discussion of the therapeutic potential of spinal interneurons for SCI injury and/or disease Represents the first book to discuss spinal interneurons and translational research

Spinal Interneurons in Sensorimotor Integration

Spinal Interneurons in Sensorimotor Integration
Author : Ting Ting Liu
Publisher : Unknown
Release Date : 2009
Category :
Total pages :271
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Even though spinal cord research has expanded enormously during the past decades, we still lack a precise understanding of how spinal interneuron networks perfectly integrate sensory feedback with motor control, and how these neuron circuits give rise to specific functions. The present study thus has three basic aims: (1) to investigate propriospinal interneurons connecting rostral and caudal lumbar spinal cord in the rat; (2) to investigate input properties of identified spinal interneurons interposed in different pathways; (3) to investigate cholinergic terminals in the ventral horn of adult rat and cat. There was no evidence to support the presence of vesicular glutamate transporters in motoneuron axon terminals of either species. In addition, there was no obvious relationship between motoneuron terminals and R2 subunit of the AMPA receptor (GluR2). However, a population of cholinergic terminals in lamina VII, which did not originate from motoneurons, was found to be immunoreactive for VGLUT2 and formed appositions with GluR2 subunits. These terminals were smaller than motoneuron terminals and, unlike them, formed no relationship with Renshaw cells. The evidence suggests that glutamate does not act as a cotransmitter with acetylcholine at central synapses of motoneurons in the adult cat and rat. However, glutamate is present in a population of cholinergic terminals which probably originate from interneurons where its action is via an AMPA receptor. In conclusion, the present studies add to the understanding of the organization of neuronal networks involved in sensorimotor integration. Propriospinal interneurons located within the lumbar segments have extensive intra-segmental projections to motor nuclei. First order interneurons interposed in reflex pathways and descending pathways receive a significantly different pattern of inputs. A similar proportion of monosynaptic excitatory input from primary afferents has been found in both excitatory and inhibitory interneurons and these two types of cells are subject to presynaptic inhibitory control of this input.

Movement Control

Movement Control
Author : Paul Cordo,Stevan Harnad
Publisher : Cambridge University Press
Release Date : 1994-05-27
Category : Medical
Total pages :276
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This volume addresses issues about how the central nervous system controls movement.

Canadian Journal of Physiology and Pharmacology

Canadian Journal of Physiology and Pharmacology
Author : Anonim
Publisher : Unknown
Release Date : 2004-06
Category : Pharmacology
Total pages :129
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The Journal of Neuroscience

The Journal of Neuroscience
Author : Anonim
Publisher : Unknown
Release Date : 2009
Category : Neurology
Total pages :129
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Autonomic Dysfunction After Spinal Cord Injury

Autonomic Dysfunction After Spinal Cord Injury
Author : Lynne C. Weaver,Canio Polosa
Publisher : Elsevier
Release Date : 2005-10-11
Category : Medical
Total pages :472
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Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions. The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions.

American Journal of Physiology

American Journal of Physiology
Author : Anonim
Publisher : Unknown
Release Date : 1977
Category : Physiology
Total pages :129
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"The William Townsend Porter memorial volume": v. 158.

Motor Neurobiology of the Spinal Cord

Motor Neurobiology of the Spinal Cord
Author : Timothy C. Cope
Publisher : CRC Press
Release Date : 2001-06-26
Category : Medical
Total pages :360
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Traumatic injuries of the spinal cord continue to be the most common cause of permanent paralysis in young adults in the United States. New information has emerged on the response of spinal neurons to injury of either the spinal cord or peripheral nerves demonstrating that dendrites of injured motoneurons take on characteristics of axons. These and other new developments have helped to promote an exciting new era in the study of spinal cord neurobiology. Motor Neurobiology of the Spinal Cord provides a description of the recent conceptual and technical advances in the field. It provides a description of the new experimental tools available for investigating the neuronal properties that allow populations of spinal cord neurons to control muscles responsible for limb movements and posture. It covers topics ranging from genetics to kinematics and examines cells, tissues, or whole animals in species ranging from fish to humans that are normal, injured, or diseased. By integrating data derived from many new approaches, you'll learn about how spinal cord circuits operate under a variety conditions and about new and exciting inroads being made in motor neurobiology of the spinal cord. Motor Neurobiology of the Spinal Cord elucidates concepts and principles relevant to function and structure throughout the nervous system and presents information about changes induced by injury and disease.

Peripheral and Spinal Mechanisms in the Neural Control of Movement

Peripheral and Spinal Mechanisms in the Neural Control of Movement
Author : M.D. Binder
Publisher : Elsevier
Release Date : 1999-12-17
Category : Science
Total pages :479
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In the last decade, we have witnessed a striking maturation of our understanding of how neurons in the spinal cord control muscular activity and movement. Paradoxically, a host of new findings have revealed an unexpected versatility in the behavior of these well-studied neural elements and circuits. In this volume, the world's leading experts review the current state of our knowledge of motor control, outline their latest results and developments, and delineate the seminal unresolved questions in this vibrant field of research. The volume begins with a commentary and overview of our current understanding of the peripheral and spinal basis of motor control. The remainder of the volume is divided into seven sections, each focused on a different problem. The first chapter in each section provides some historical review and presages the experimental findings and hypotheses that are discussed in subsequent chapters. Topics include the biomechanics of neuromuscular systems, the properties of motoneurons and the muscle units they control, spinal interneurons, pattern generating circuits, locomotion, descending control of spinal circuits, comparative physiology of motor systems, and motor systems neurophysiology studied in man. The book serves as a unique reference volume and should be essential reading for anyone interested in motor systems. Moreover, the volume's comprehensive coverage of a wide range of topics make it an effective textbook for graduate level courses in motor control neurobiology, kinesiology, physical therapy, and rehabilitation medicine.

Pathology of Spinal Interneurons in Motor Neuron Disease

Pathology of Spinal Interneurons in Motor Neuron Disease
Author : Benjamin Stephens,University of London (GB)
Publisher : Unknown
Release Date : 2001
Category :
Total pages :129
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Textbook of Neuroanatomy

Textbook of Neuroanatomy
Author : Alvin M. Burt
Publisher : Unknown
Release Date : 1993
Category : Neuroanatomie
Total pages :541
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Textbook of Physiology: Excitable cells and neurophysiology

Textbook of Physiology: Excitable cells and neurophysiology
Author : William Henry Howell
Publisher : W B Saunders Company
Release Date : 1989
Category : Medical
Total pages :1596
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生物圈科学

生物圈科学
Author : Anonim
Publisher : Unknown
Release Date : 2002
Category : Agriculture
Total pages :129
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The Synaptic Organization of the Brain

The Synaptic Organization of the Brain
Author : Adrian Shepherd
Publisher : Oxford University Press, USA
Release Date : 1998
Category : Science
Total pages :638
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In this volume, leading authorities have joined together to provide accounts of the best understood brain regions. Each contributor uses the same format in covering the neural elements, synaptic connections, basic circuits, physiology, pharmacology, dendritic properties and functional implications of brain structures, so that readers can easily recognize common principles and specific adaptations. A new chapter on the cochlear nucleus highlights the neural basis of audition, and supplements the analyses of vision in the retina, lateral geniculate and visual cortex, and of olfaction in the olfactory bulb and cortex.

Neural Mechanisms Underlying the Clasp-knife Reflex in the Cat

Neural Mechanisms Underlying the Clasp-knife Reflex in the Cat
Author : Corey Lee Cleland
Publisher : Unknown
Release Date : 1984
Category :
Total pages :306
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