November 27, 2020

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Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Michael Harmata
Publisher : Academic Press
Release Date : 2019-11-19
Category : Science
Total pages :350
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Strategies and Tactics in Organic Synthesis, Volume 14, provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure, and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs, and building molecules with atom and step economies that provide functional solutions to create a better world. Presents state-of-the-art developments in organic synthesis Provides insights and offers new perspectives on problem-solving Written by leading experts in the field Uses firsthand narrative accounts to vividly illustrate the challenges and joys involved in advancing the science of organic synthesis

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Michael Harmata
Publisher : Unknown
Release Date : 1984
Category : Organic compounds
Total pages :129
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Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Michael Harmata
Publisher : Elsevier
Release Date : 2015-08-13
Category : Science
Total pages :442
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Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project tell of the excitement of conception, the frustration of failure, and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done. Readers will be educated, challenged, and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs, and building molecules with atom and step economies that provide functional solutions to create a better world. Presents state-of-the-art developments in organic synthesis Provides insight and offers new perspective to problem-solving Written by leading experts in the field Uses firsthand narrative accounts to illustrate vividly the challenges and joys involved in advancing the science of organic synthesis

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Thomas James Lindberg
Publisher : Unknown
Release Date : 2008
Category : Organic compounds
Total pages :129
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Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Anonim
Publisher : Academic Press
Release Date : 2016-10-04
Category : Science
Total pages :294
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Strategies and Tactics in Organic Synthesis provides a forum for investigators to discuss their approach to the science and art of organic synthesis. Rather than a simple presentation of data or a secondhand analysis, this classic provides stories that vividly demonstrate the power of the human endeavor known as organic synthesis and the creativity and tenacity of its practitioners. Firsthand accounts of each project present the excitement of conception, the frustration of failure, and the joy experienced when either rational thought or good fortune gives rise to the successful completion of a project. This book series shows how synthesis is really done. Readers will be educated, challenged, and inspired by these accounts, which portray the idea that triumphs do not come without challenges. This innovative approach also helps illustrate how challenges to further advance the science and art of organic synthesis can be overcome, driving the field forward to meet the demands of society by discovering new reactions, creating new designs, and building molecules with atom and step economies that provide functional solutions to create a better world. Presents state-of-the-art developments in organic synthesis Provides insight and offers new perspective to problem-solving Written by leading experts in the field Uses firsthand narrative accounts to vividly illustrate the challenges and joys involved in advancing the science of organic synthesis

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Thomas Lindberg
Publisher : Academic Press
Release Date : 2012-12-02
Category : Science
Total pages :552
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Strategies and Tactics in Organic Synthesis, Volume 3 provides detailed accounts of interesting advances in the field of synthesis. This book discusses the tasks of multistep synthesis from finding the proper reagents, reaction, and conditions for individual steps to inventing new chemistry to fill gaps in existing synthetic methodology. Organized into 13 chapters, this volume begins with an overview of the development of redox glycosidation strategy through ester methylenation. This text then examines the development of computer-assisted molecular modeling with applications to a wide range of problems in biological and organic chemistry. Other chapters consider the medicinal significance of ginkgo tree, which has prompted systematic studies to correlate the claimed beneficial effects of its extracts to the active principles. This book discusses as well the biological potency of pentacyclic quassinoids. The final chapter deals with the economic synthesis of a penem antibacterial. This book is a valuable resource for chemists.

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Michael J. Hudson,Frank W. Lewis,Laurence M. Harwood
Publisher : Elsevier Inc. Chapters
Release Date : 2013-07-29
Category : Science
Total pages :344
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This account describes the scientific events that have led from malonamides which coextract minor actinide and lanthanide fission products, to the 1,2,4-triazines such as BTBP and BTPhen reagents that are capable of separating Am(III) from Eu(III). The journey started with Mike Hudson having a walk in hot and dusty Rome with Claude Musikas of the CEA in 1980 and continues to Mike enjoying a celebratory beer (or two) in Reading (2012) with Laurence Harwood and Frank Lewis. Throughout the journey, organic synthesis, coupled with coordination chemistry, has been the engine by which successful science has developed.

Organic Synthesis

Organic Synthesis
Author : Paul Wyatt,Stuart Warren
Publisher : John Wiley & Sons
Release Date : 2013-05-20
Category : Science
Total pages :920
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Organic Synthesis: Strategy and Control is the long-awaited sequel to Stuart Warren’s bestseller Organic Synthesis: The Disconnection Approach, which looked at the planning behind the synthesis of compounds. This unique book now provides a comprehensive, practical account of the key concepts involved in synthesising compounds and focuses on putting the planning into practice. The two themes of the book are strategy and control: solving problems either by finding an alternative strategy or by controlling any established strategy to make it work. The book is divided into five sections that deal with selectivity, carbon-carbon single bonds, carbon-carbon double bonds, stereochemistry and functional group strategy. A comprehensive, practical account of the key concepts involved in synthesising compounds Takes a mechanistic approach, which explains reactions and gives guidelines on how reactions might behave in different situations Focuses on reactions that really work rather than those with limited application Contains extensive, up-to-date references in each chapter Students and professional chemists familiar with Organic Synthesis: The Disconnection Approach will enjoy the leap into a book designed for chemists at the coalface of organic synthesis.

Introduction to Strategies for Organic Synthesis

Introduction to Strategies for Organic Synthesis
Author : Laurie S. Starkey
Publisher : John Wiley & Sons
Release Date : 2018-03-23
Category : Science
Total pages :432
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Bridging the Gap Between Organic Chemistry Fundamentals and Advanced Synthesis Problems Introduction to Strategies of Organic Synthesis bridges the knowledge gap between sophomore-level organic chemistry and senior-level or graduate-level synthesis to help students more easily adjust to a synthetic chemistry mindset. Beginning with a thorough review of reagents, functional groups, and their reactions, this book prepares students to progress into advanced synthetic strategies. Major reactions are presented from a mechanistic perspective and then again from a synthetic chemist’s point of view to help students shift their thought patterns and teach them how to imagine the series of reactions needed to reach a desired target molecule. Success in organic synthesis requires not only familiarity with common reagents and functional group interconversions, but also a deep understanding of functional group behavior and reactivity. This book provides clear explanations of such reactivities and explicitly teaches students how to make logical disconnections of a target molecule. This new Second Edition of Introduction to Strategies for Organic Synthesis: Reviews fundamental organic chemistry concepts including functional group transformations, reagents, stereochemistry, and mechanisms Explores advanced topics including protective groups, synthetic equivalents, and transition-metal mediated coupling reactions Helps students envision forward reactions and backwards disconnections as a matter of routine Gives students confidence in performing retrosynthetic analyses of target molecules Includes fully-worked examples, literature-based problems, and over 450 chapter problems with detailed solutions Provides clear explanations in easy-to-follow, student-friendly language Focuses on the strategies of organic synthesis rather than a catalogue of reactions and modern reagents The prospect of organic synthesis can be daunting at the outset, but this book serves as a useful stepping stone to refresh existing knowledge of organic chemistry while introducing the general strategies of synthesis. Useful as both a textbook and a bench reference, this text provides value to graduate and advanced undergraduate students alike.

Silver in Organic Chemistry

Silver in Organic Chemistry
Author : Michael Harmata
Publisher : John Wiley & Sons
Release Date : 2011-01-11
Category : Science
Total pages :402
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The first authoritative book on using silver cations in organic chemistry—for catalysis and more! With more sophisticated catalytic methodologies fueling a resurgence in the study of cation-based chemistry, gold and platinum have stepped to the fore as the unique agents used to create new chemical reactions. Although these metals have become a primary focus of researchers in the field, another coinage metal that is often overlooked—but is as powerful as the others—is silver, a far less costly alternative to gold and platinum in aiding the development of new reactions. Making a strong case for the use of silver as a catalyst and structural element in organometal constructs, this authoritative book is the first to explore the benefits of using silver in organic chemistry by taking a close look at silver’s unique reactivity and structural characteristics for the development of new methods and materials. Silver in Organic Chemistry is: The first book to address catalysis using silver, whose use in organic chemistry is on the verge of exploding A resource for researchers wishing to do chemistry with silver cations, an area that stands in the shadow of gold chemistry, but still glistens, demonstrating that all that glitters is not gold—sometimes it’s silver! A guide for “first attempts” in working with silver cations Edited by a very well-respected, highly visible authority in this field Silver in Organic Chemistry promotes further scientific discussion by offering important new ways to examine the future possibilities of an emerging field. By elevating the importance of silver chemistry, this thought-provoking guide illustrates how this versatile metal can become an increasingly significant player in opening the door to new catalytic organic reactions and new organometal materials.

Protecting-Group-Free Organic Synthesis

Protecting-Group-Free Organic Synthesis
Author : Rodney A. Fernandes
Publisher : John Wiley & Sons
Release Date : 2018-08-20
Category : Science
Total pages :288
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Presents a comprehensive account of established protecting-group-free synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protecting-group-free synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protecting-group-free synthesis. Following this, the book presents information on protecting-group-free synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protecting-group-free synthesis using carbohydrates and of glycosyl derivatives, glycol-polymers and glyco-conjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protecting-group-free synthesis. A comprehensive account of established protecting-group-free (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical Protecting-Group-Free Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.

Organic Synthesis

Organic Synthesis
Author : W. A. Smit,William A. Smit,Alekseĭ Feodosʹevich Bochkov,Ron Caple
Publisher : Royal Society of Chemistry
Release Date : 1998
Category : Science
Total pages :477
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A concise and readable account of the role of synthesis in modern science, Organic Synthesis.

The Algebra of Organic Synthesis

The Algebra of Organic Synthesis
Author : John Andraos
Publisher : CRC Press
Release Date : 2016-04-19
Category : Science
Total pages :1221
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The Algebra of Organic Synthesis combines the aims, philosophies, and efforts involved in organic synthesis, reaction optimization, and green chemistry with techniques for determining quantitatively just how "green" synthesis plans are. It provides the first complete quantitative description of synthesis strategy analysis in the context of green ch

Molecular Rearrangements in Organic Synthesis

Molecular Rearrangements in Organic Synthesis
Author : Christian M. Rojas
Publisher : John Wiley & Sons
Release Date : 2015-10-26
Category : Science
Total pages :776
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Designed for practitioners of organic synthesis, this book helps chemists understand and take advantage of rearrangement reactions to enhance the synthesis of useful chemical compounds. Provides ready access to the genesis, mechanisms, and synthetic utility of rearrangement reactions Emphasizes strategic synthetic planning and implementation Covers 20 different rearrangement reactions Includes applications for synthesizing compounds useful as natural products, medicinal compounds, functional materials, and physical organic chemistry

Strategies and Tactics in Organic Synthesis

Strategies and Tactics in Organic Synthesis
Author : Thomas Lindberg
Publisher : Elsevier
Release Date : 2013-10-22
Category : Science
Total pages :469
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This is a unique account of the synthesis of organic molecules. All of the contributors are acknowledged experts in organic synthesis.