January 21, 2021

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Surface Modification of Biomaterials

Surface Modification of Biomaterials
Author : Rachel Williams
Publisher : Elsevier
Release Date : 2010-11-25
Category : Medical
Total pages :432
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The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material’s surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance. Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone. The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification. Reviews both established surface modifications and those still in the early stages of research and how they can be used to optimise biological interactions and enhance clinical performance Studies analytical techniques and applications of surface modification with chapters assessing biomaterial surface chemistry, surface structure, morphology and topography Discusses modifying biomaterial surfaces to optimise interactions with blood and soft tissues and also to repair and regenerate nerve cells and control infection

Laser Surface Modification of Biomaterials

Laser Surface Modification of Biomaterials
Author : Rui Vilar
Publisher : Woodhead Publishing
Release Date : 2016-04-15
Category : Technology & Engineering
Total pages :350
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Laser Surface Modification of Biomaterials: Techniques and Applications covers this expanding field, which has many potential applications, including biomaterials. Laser surface modification of biomaterials enables the production of hybrid materials with different functionality in the bulk as well as the thin, sub-micrometer surface layer. This book will provide readers with a comprehensive review of the technology and its applications. Chapters in Part 1 look at the techniques and considerations of laser surface modification, while Part 2 reviews laser surface modification techniques of the most important classes of biomaterials, with a final set of chapters discussing application specific laser surface modification. Offers a comprehensive review of laser surface modification techniques Presents recent developments, fundamentals, and progress in laser surface modification Reviews laser surface modification applications across a range of materials Emphasizes applications in biomaterials

Surface Coating and Modification of Metallic Biomaterials

Surface Coating and Modification of Metallic Biomaterials
Author : Cuie Wen
Publisher : Woodhead Publishing
Release Date : 2015-03-31
Category : Technology & Engineering
Total pages :448
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Despite advances in alternative materials, metals are still the biomaterial of choice for a number of clinical applications such as dental, orthopedic and cardiac implants. However, there are a number of intrinsic problems associated with implanting metal in the biological environment, such as wear, corrosion, biocompatibility and toxicity, which must be addressed. Modern technology has enabled scientists to modify metal surfaces or apply special coatings to metals to improve their performance safety. Surface Coating and Modification of Metallic Biomaterials will discuss the most important modification techniques and coatings for metals, first covering the fundamentals of metals as a biomaterial and then exploring surface modification techniques and coatings. An expansive overview of surface modification techniques for biomedical use In-depth exploration of issues arising from metal biomaterial use Includes examples of applications in a clinical setting

Surface Modification of Polymeric Biomaterials

Surface Modification of Polymeric Biomaterials
Author : Buddy D. Ratner,David G. Castner
Publisher : Springer Science & Business Media
Release Date : 2013-06-29
Category : Science
Total pages :206
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Applications of synthetic materials in medicine date back over 4000 year2. The Egyptians used linen as sutures. In the Roman Empire, gold was used in dentistry. Perhaps even earlier, ivory and bone may have been used in the body by practitioners of the healing arts. The historical origins of modem biomaterials science are also hard to precisely trace, but many of the ideas that define biomaterials as we know them today evolved in the late 1950s and early 1960s. Surface modification technology has played a prominent role in biomaterials science, and has paralleled the evolution of the modem field. In a symposium organized by the Artifical Heart Program of the NIH National Heart Institute and the Artificial Kidney program of the NIH National Institute of Arthritis and Metabolic Diseases, held in Atlantic City, New Jersey, in 1968, there were already a number of presentations on surface modification. Surface characterization at that time included scanning electron microscopy, ellipsometry, contact angle methods, and infrared internal reflection methods.

Advances in Biomaterials for Biomedical Applications

Advances in Biomaterials for Biomedical Applications
Author : Anuj Tripathi,Jose Savio Melo
Publisher : Springer
Release Date : 2017-01-24
Category : Technology & Engineering
Total pages :545
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This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.

Biomaterials Surface Science

Biomaterials Surface Science
Author : Andreas Taubert,Joao F. Mano,José Carlos Rodríguez-Cabello
Publisher : John Wiley & Sons
Release Date : 2013-07-23
Category : Science
Total pages :616
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At the interface of biology, chemistry, and materials science, this book provides an overview of this vibrant research field, treating the seemingly distinct disciplines in a unified way by adopting the common viewpoint of surface science. The editors, themselves prolific researchers, have assembled here a team of top-notch international scientists who read like a "who's who" of biomaterials science and engineering. They cover topics ranging from micro- and nanostructuring for imparting functionality in a top-down manner to the bottom-up fabrication of gradient surfaces by self-assembly, from interfaces between biomaterials and living matter to smart, stimuli-responsive surfaces, and from cell and surface mechanics to the elucidation of cell-chip interactions in biomedical devices. As a result, the book explains the complex interplay of cell behavior and the physics and materials science of artificial devices. Of equal interest to young, ambitious scientists as well as to experienced researchers.

Surface Modification of Magnesium and its Alloys for Biomedical Applications

Surface Modification of Magnesium and its Alloys for Biomedical Applications
Author : T.S.N. Sankara Narayanan,Il-Song Park,Min-Ho Lee
Publisher : Elsevier
Release Date : 2015-01-30
Category : Technology & Engineering
Total pages :460
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The development of biodegradable implants which can remain in the human body to fix a problem and subsequently dissolve, or be absorbed, consumed or excreted, without warranting a secondary surgery, is very appealing to scientists. Due to their excellent biocompatibility and biodegradability, magnesium implants provide a viable option many problems associated with permanent metallic implants such as, restenosis, thrombosis, permanent physical irritation, and inability to adapt to growth and changes in human body. Volume 2 of this important new book explores practical issues of magnesium and magnesium alloys, physical and mechanical modification and coatings to enhance this material for biomedical applications. Includes expert analysis on chemical solution deposition of hydroxyapatite (HAp) and octacalcium (OCP) phosphate coatings for magnesium Comprehensive coverage of biomimetic modifications, surface functionalization of biomolecules, natural, conducting and biodegradable polymeric coatings Lucid dissection of chemical, physical, mechanical and electromechanical modifications of magnesium and its alloys for biomedical applications

Additive Manufacturing

Additive Manufacturing
Author : Amit Bandyopadhyay,Susmita Bose
Publisher : CRC Press
Release Date : 2015-09-08
Category : Technology & Engineering
Total pages :389
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The field of additive manufacturing has seen explosive growth in recent years due largely in part to renewed interest from the manufacturing sector. Conceptually, additive manufacturing, or industrial 3D printing, is a way to build parts without using any part-specific tooling or dies from the computer-aided design (CAD) file of the part. Today, most engineered devices are 3D printed first to check their shape, size, and functionality before large-scale production. In addition, as the cost of 3D printers has come down significantly, and the printers’ reliability and part quality have improved, schools and universities have been investing in 3D printers to experience, explore, and innovate with these fascinating additive manufacturing technologies. Additive Manufacturing highlights the latest advancements in 3D printing and additive manufacturing technologies. Focusing on additive manufacturing applications rather than on core 3D printing technologies, this book: Introduces various additive manufacturing technologies based on their utilization in different classes of materials Discusses important application areas of additive manufacturing, including medicine, education, and the space industry Explores regulatory challenges associated with the emergence of additive manufacturing as a mature technological platform By showing how 3D printing and additive manufacturing technologies are currently used, Additive Manufacturing not only provides a valuable reference for veteran researchers and those entering this exciting field, but also encourages innovation in future additive manufacturing applications.

Surfaces and Interfaces for Biomaterials

Surfaces and Interfaces for Biomaterials
Author : Pankaj Vadgama
Publisher : CRC Press
Release Date : 2005-06-14
Category : Technology & Engineering
Total pages :802
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Given such problems as rejection, the interface between an implant and its human host is a critical area in biomaterials. Surfaces and Interfaces for Biomaterials summarizes the wealth of research on understanding the surface properties of biomaterials and the way they interact with human tissue. The first part of the book reviews the way biomaterial surfaces form. Part Two then discusses ways of monitoring and characterizing surface structure and behavior. The final two parts of the book look at a range of in vitro and in vivo studies of the complex interactions between biomaterials and the body. Chapters cover such topics as bone and tissue regeneration, the role of interface interactions in biodegradable biomaterials, microbial biofilm formation, vascular tissue engineering and ways of modifying biomaterial surfaces to improve biocompatibility. Surfaces and Interfaces for Biomaterials will be a standard work on how to understand and control surface processes in ensuring biomaterials are used successfully in medicine.

The Role of Surface Modification on Bacterial Adhesion of Bio-implant Materials

The Role of Surface Modification on Bacterial Adhesion of Bio-implant Materials
Author : Santhosh Kumar S,Somashekhar S. Hiremath
Publisher : CRC Press
Release Date : 2020-08-09
Category : Science
Total pages :148
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The Role of Surface Modification on Bacterial Adhesion of Bio-implant Materials: Machining, Characterization, and Applications, explores the relationship between the surface roughness of artificial implants used for hard tissue replacement and their bacterial adhesion. It summarizes the reason for the failure of implants, the mechanisms of bacterial formation on implant surfaces, and the fundamental and established methods of implant surface modification techniques. It provides readers with an organized and rational representation about implant manufacturing and mechanical surface modification. It also explores the use of developed unidirectional abrasive flow finishing processes to finish biomaterials at the nano-level. It is an invaluable guide for academics, graduate students, biomaterial scientists, and manufacturing engineers researching implants, related infections, and implant manufacturing. Key Features: Explores implant related infections Discusses surface modification techniques Contains information on the mechanical finishing processes and complete guide on developed cutting edge unidirectional abrasive flow finishing technology

Water in Biomaterials Surface Science

Water in Biomaterials Surface Science
Author : Marco Morra
Publisher : John Wiley & Sons
Release Date : 2001-08-30
Category : Technology & Engineering
Total pages :408
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Presents the latest ideas and research on molecular hydration and hydration forces, and how they determine the interaction between water molecules and biomaterials surfaces. Consisting of three sections; theoretical aspects, analytical aspects and practical applications, it begins by placing the properties of water in a proper molecular perspective. The analytical aspects and practical applications offer a complete overview with new insights into the biomaterials/water interface by: - Discussing the latest approaches to the characterisation of water at interfaces and surface modification of biomaterials - Examining the problems related to the understanding and characterisation of interfacial water - Providing new perspectives of the interfacial interactions between materials and the physiological aqueous environment An invaluable resource for researchers in biomaterials surface science and the biotechnology industry.

Functionalized Nanomaterials I

Functionalized Nanomaterials I
Author : Vineet Kumar,Praveen Guleria,Nandita Dasgupta,Shivendu Ranjan
Publisher : CRC Press
Release Date : 2020-08-10
Category : Medical
Total pages :318
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Nanomaterials contain some unique properties compared to their bulk. Their unique properties are due to the chemical nature of the material, small size, and surface functionalization. Along with control over size, the functionalization of nanomaterials also affects their compatibility to the environment and living organisms. This book provides a detailed account of nanomaterials functionalization along with a brief overview of their application. This book serves as a reference for scientific investigators including doctoral and postdoctoral scholars and undergradate and graduate students who need to have knowledge of the basics of nanomaterial functionalization, recent advancements, challenges, and opportunities in this field. This book will also provide critical and comparative data for nano-technologists and may be beneficial for industry personnel, journalists, policy makers, and the general public to help understand functionalized nanomaterials in detail and in depth. Features: This book is comprehensive and covers all aspects of functionalized nanotechnology. It describes the challenges and methods of functionalized nanomaterials synthesis for different applications. It discusses the recent findings and cutting-edge global research trends on the functionalization of nanomaterials. It emphasizes the products and market, safety, and regulatory issues of functionalized nanomaterials. It contains contributions from international experts and will be a valuable resource for researchers.

Dental Implants

Dental Implants
Author : Muhammad Sohail Zafar,Zohaib Khurshid
Publisher : Woodhead Publishing
Release Date : 2020-07-23
Category : Medical
Total pages :324
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Dental Implants: Materials, Coatings, Surface Modifications and Interfaces with Oral Tissues provides readers with information on past and contemporary advances in the design and modification of dental implants to enhance osseointegration and biocompatibility. The book begins with a look at the current status of dental implants, materials and fabrication methods. Chapters then cover surface modification techniques and a variety of inorganic, organic and biological coatings. Final sections cover tissue-implant interfaces. Written by a multidisciplinary team of materials scientists, dental clinicians and implantologists, this book is an essential reference for materials scientists, dental practitioners and researchers and students in academia. Covers all aspects related to dental implants, including implant materials science, their fabrication, surface coatings and their clinical applications Provides detailed information on surface modification on surfaces coated with inorganic, organic and biological materials Discusses the modification of dental implants, including implant-bone interaction enhanced by coatings on dental implant surfaces Written by a multidisciplinary team of materials scientists, dental clinicians and Implantologists

Engineering Materials for Biomedical Applications

Engineering Materials for Biomedical Applications
Author : Teoh Swee Hin
Publisher : World Scientific
Release Date : 2004-10-21
Category : Medical
Total pages :352
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The success of any implant or medical device depends very much on the biomaterial used. Synthetic materials (such as metals, polymers and composites) have made significant contributions to many established medical devices. The aim of this book is to provide a basic understanding on the engineering and processing aspects of biomaterials used in medical applications. Of paramount importance is the tripartite relationship between material properties, processing methods and design. As the target audiences cover a wide interdisciplinary field, each chapter is written with a detailed background so that audience of another discipline will be able to understand. For the more knowledgeable reader, a detailed list of references is included. Contents:Introduction to Biomaterials Engineering and Processing — An Overview (S H Teoh)Durability of Metallic Implant Materials (M Sumita & S H Teoh)Corrosion of Metallic Implants (D J Blackwood et al.)Surface Modification of Metallic Biomaterials (T Hanawa)Biorestorative Materials in Dentistry (A U J Yap)Bioceramics: An Introduction (B Ben-Nissan & G Pezzotti)Polymeric Hydrogels (J Li)Bioactive Ceramic-Polymer Composites for Tissue Replacement (M Wang)Composites in Biomedical Applications (Z M Huang & S Ramakrishna)New Methods and Materials in Prosthetics for Rehabilitation of Lower Limb Amputees (P V S Lee)Chitin-Based Biomaterials (E Khor) Readership: Undergraduates and postgraduates (in bioengineering, materials science and engineering, mechanical engineering, dental and orthopaedic departments), engineers, researchers, academics/lecturers and industrialists. Keywords:Biomaterials Engineering and Processing;Durability of Metallic Implants;Surface Modification;Dental Materials;Bioceramics;Polymeric Hydrogels;Composites;Prosthetics;ChitinKey Features:Contains detailed information on the latest biomaterials (such as polymers, metals, ceramics and composites ) used in medical devicesProvides a good understanding into the durability issues such as an in-depth treatment of corrosion and fretting fatigue of metallic implantsIt leads the reader to have a greater appreciation on the need for surface modification so as to enable the medical device to have the appropriate tissue response

Introduction to Biomaterials

Introduction to Biomaterials
Author : J. L. Ong,Mark R. Appleford,Gopinath Mani
Publisher : Cambridge University Press
Release Date : 2013-11-07
Category : Medical
Total pages :419
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A succinct introduction to the field of biomaterials engineering, packed with practical insights.