April 14, 2021

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Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author : Caroline Gordon,David Isenberg
Publisher : Oxford University Press
Release Date : 2016-03-10
Category : Systemic lupus erythematosus
Total pages :160
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Systemic Lupus Erythematosus (often abbreviated to SLE or lupus) is a systemic autoimmune disease that can affect any part of the body, causing the immune system to attack the body's cells and tissue, and resulting in inflammation and tissue damage. This new addition to the Oxford Rheumatology Library series provides a practical approach to the assessment and management of patients with this complex, multisystem autoimmune disease to improve the diagnosis and treatment of the disease and its complications. It provides comprehensive but easy to assimilate reading for consultant rheumatologists, dermatologists, nephrologists, obstetricians and other specialists and their trainees, interested GPs, specialist nurses, and clinical trial teams both in hospitals and contract research organizations.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author : George C. Tsokos,Caroline Gordon,Josef S. Smolen
Publisher : Elsevier Health Sciences
Release Date : 2007-01-01
Category : Medical
Total pages :586
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This new companion to Hochberg et al.'s Rheumatology masterwork provides new insights into the causes, detection and therapy of this challenging disease. In this state-of-the-art resource, you'll find 'one stop' coverage of all the latest scientific and clinical developments in SLE: new concepts in epidemiology, disease activity measures and outcomes; new concepts in immunoregulation, genetic and pathogenic mechanisms; new understanding and novel presentation of the processes of tissue/organ damage; comprehensive coverage of clinical features; and the very latest concepts in treatment. Provides the very latest understanding of the pathogenesis of SLE. Distills current understanding of the cellular, molecular, genetic and environmental factors that instigate and drive the disease. Includes comprehensive coverage of clinical features, including fatigue, organ system manifestations, overlap syndromes, infections, and more. Conveys the very latest understanding of mechanisms of tissue damage, including immune complexes, antibodies, and other mechanisms that lead to organ damage. Contains expert discussion of processes that are responsible for tissue injury - a hallmark of this text. Incorporates the latest treatment modalities, including steroids and non-steroidals, cytotoxic drug treatment, PAP's, and therapies on the horizon. Discusses the latest treatment options on disease modifying or disease controlling agents.

Dubois' Lupus Erythematosus

Dubois' Lupus Erythematosus
Author : Daniel Jeffrey Wallace,Bevra Hahn
Publisher : Lippincott Williams & Wilkins
Release Date : 2007
Category : Medical
Total pages :1414
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Established for forty years as the definitive reference on lupus, Dubois' Lupus Erythematosus is now in its thoroughly revised, updated Seventh Edition. More than ninety distinguished contributing authors—twenty of them new to this edition—provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition focuses on evidence-based findings, treatment consensuses, and practical clinical information. New chapters cover cytokines and interferons, pathogenesis of atherosclerosis, immune tolerance, clinical indices in assessment of lupus, mixed connective tissue disease, reproductive issues, fibromyalgia, gender-related issues, and biomarkers.

Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus (SLE)
Author : Syuichi Koarada
Publisher : Nova Biomedical
Release Date : 2013-01-01
Category : Medical
Total pages :120
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Systemic lupus erythematosus (SLE) is one of the prototypical systemic autoimmune diseases characterized by inflammation, immune complex deposition, and vasculitis.?Patients with SLE show various symptoms and clinical images, both constitutional and specific organ symptoms. They include the skin, joints, muscles, kidneys, lungs, nervous system, and blood vessels. Although the etiology of the disease is still unclear, genetic, hormonal, immunologic abnormalities and environmental factors complicatedly play important roles in the pathophysiology in SLE. It is evident that multiple genes show genetic susceptibility to SLE. Environmental factors of SLE and immunologic abnormalities, especially the production of a number of auto-antibody, are important features of the disease. In this book, we present recent knowledge about the prevalence, pathophysiology and prognosis of SLE. The book includes various interesting chapters: Chapter One - an illustrated overview of the prevalence and clinical symptoms of systemic lupus erythematosus; Chapter Two - the pathophysiology of systemic lupus erythematosus; Chapter Three - MBL and MBL genotypes in SLE; Chapter Four - novel biological activities of autoantibodies as the potential markers of systematic lupus erythematosus; Chapter Five - cytokines in systemic lupus erythematosus (sle) with clinical aspects and prognostics; Chapter Six - prognosis in systemic lupus erythematosus; and Chapter Seven - autoantibody-producing RP105-negative B cells in humans and a murine model of lupus erythematosus.

Antiphospholipid Antibody Syndrome

Antiphospholipid Antibody Syndrome
Author : Pier Luigi Meroni
Publisher : Springer
Release Date : 2014-11-20
Category : Medical
Total pages :267
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This book, part of the series Rare Diseases of the Immune System, offers comprehensive, up-to-date coverage of the pathophysiology and management of the antiphospholipid syndrome (APS). Immunologic and genetic aspects are discussed and the pathogenic mechanisms responsible for such phenomena as APS-mediated thrombosis and pregnancy loss/complications are explained. The main clinical manifestations, classification criteria and diagnostic tools are identified, and close attention is paid to the nature of the involvement of various organs or organ systems in APS. Specific chapters describe the treatment of the different symptoms, therapies of value in avoiding recurrences, and innovative treatment approaches. The authors are senior experts in the field who are aided by younger fellows, ensuring that the book is also educationally oriented. This handy volume will be a valuable tool for postgraduates in training and professionals wishing to extend their knowledge of this specific syndrome.

Neuropsychiatric Systemic Lupus Erythematosus

Neuropsychiatric Systemic Lupus Erythematosus
Author : Shunsei Hirohata
Publisher : Springer
Release Date : 2018-04-03
Category : Medical
Total pages :189
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Neuropsychiatric manifestation in systemic lupus erythematosus (NPSLE) is one of the most recalcitrant complications of the disease. According to the 1999 ACR nomenclature and case definitions, diffuse psychiatric/neuropsychological syndromes in NPSLE (anxiety disorder, acute confusional state, cognitive dysfunction, mood disorder, psychosis) (diffuse NPSLE) present psychiatric manifestations unlike neurologic syndromes (focal NPSLE) originating from focal CNS lesions, such as cerebrovascular disease, demyelinating syndrome, headache, aseptic meningitis, chorea, seizures and myelopathy. A number of studies have reported that diffuse NPSLE is usually associated with the presence of autoantibodies against neuronal cells in serum as well as in cerebrospinal fluid (CSF). Moreover, IL-6 has been shown to be elevated in CSF of patients with diffuse NPSLE. Recently, it has been demonstrated that the severity of blood-brain barrier damages plays a crucial role in the development of acute confusional state, the severest form of diffuse NPSLE through the accelerated entry of larger amounts of autoantibodies to NMDA receptor subunit NR2 into the CNS. Since the importance of autoantibodies in the NPSLE has been now evident, such an aggressive treatment, especially B cell depleting therapy, would make sense in that it would reduce the levels of pathogenic autoantibodies, leading to a better prognosis of NPSLE. As far as we know, no single book specifically dedicated to NPSLE alone has been published as yet. As mentioned above, NPSLE constitutes a vastly expanding field of research with increasing numbers of papers published annually. Therefore, we believe that an effort to collect and critically review these publications is invaluable. Such an effort will provide an important contribution to basic researchers as well as clinicians working in the field of neurology, rheumatology, psychiatry and internal medicine fields.

Advanced Handbook of Systemic Lupus Erythematosus

Advanced Handbook of Systemic Lupus Erythematosus
Author : Laurent Arnaud,Ronald van Vollenhoven
Publisher : Springer
Release Date : 2017-09-10
Category : Medical
Total pages :167
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This book will provide an introduction to the epidemiology, etiology and pathogenesis of the condition while also exploring the classification, diagnosis, and current and emerging therapies for systemic lupus erythematosus. Systemic lupus erythematosus is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue. It can affect the skin, joints, kidneys, brain, and other organs. The underlying cause of the disease is not fully known, and SLE is much more common in women than in men. It may occur at any age but most often occurs in people between 10 and 50 years of age. This is the second Adis title from Ronald F van Vollenhoven, who previously authored Biologics for the Treatment of Rheumatoid Arthritis.

Lupus Erythematosus

Lupus Erythematosus
Author : Peter H. Schur,Elena M. Massarotti
Publisher : Springer Science & Business Media
Release Date : 2012-07-06
Category : Medical
Total pages :260
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Often considered the prototypic autoimmune disease, Lupus is characterized by protean manifestations and affects a wide range of organ systems. Despite widespread availability of anti nuclear antibody testing and other technological diagnostic advances, the diagnosis of lupus can be elusive, difficult, and inexact. Treatment of the disease can also be challenging. Advances in immunology and biotechnology have led to a burgeoning world of new therapies in development that offer patients the real possibility of new therapies and physicians and scientists novel insights into the pathogenesis of this complicated immunological disease. Lupus Erythematosus: Clinical Evaluation and Treatment summarizes the clinical aspects of lupus facing the general clinician in the 21st century. In this invaluable, practical book, the reader will find introductory chapters regarding general diagnostic and treatment principles, followed by chapters addressing the lupus-specific organ manifestations. Special topics regarding pregnancy and comorbidities are also presented. Written by highly experienced physicians with special expertise in lupus, Lupus Erythematosus: Clinical Evaluation and Treatment is an indispensable reference for the common and not so common problems affecting patients with lupus.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author : Robert G. Lahita
Publisher : Elsevier
Release Date : 2004-06-09
Category : Medical
Total pages :1343
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Systemic Lupus Erythematosus, Fourth Edition, provides an understanding of the basic mechanisms as well as the diagnostic and therapeutic aspects of lupus. This book is attractive to both the investigative community and clinicians. As lupus has become a paradigm for the study of autoimmune disease, immunologists investigating autoimmunity are becoming more interested in lupus. Basic immunology of phospholipid antibodies, clotting abnormailities, issues concerning pathogenetic fit with SLE, and newest methods of therapy of APLS are given in this newest edition of a classic reference. * Comprehensive current coverage of basic models of etiology and pathogenesis * Complete catalog of autoantibodies produced * Includes an outstanding review of imaging techniques for the diagnosis of lupus and its complications for each organ system * Includes CD-ROM of images excellent for teaching purposes and downloading into presentations

Oxford Textbook of Rheumatology

Oxford Textbook of Rheumatology
Author : Richard A Watts,Philip Conaghan,Chris Denton,Helen Foster,John Isaacs,Ulf Müller-Ladner
Publisher : Oxford University Press
Release Date : 2013-10
Category : Medical
Total pages :1522
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This fourth edition of the Oxford Textbook of Rheumatology provides a complete overview of all rheumatological and musculoskeletal problems, and is a comprehensive reference for all trainees and specialists in the field.

The Lupus Book

The Lupus Book
Author : Daniel J. Wallace
Publisher : Oxford University Press
Release Date : 2012-11-27
Category : Health & Fitness
Total pages :304
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Lupus, a disease of the immune system, can be quite deadly, claiming the lives of thousands of patients yearly. Dr. Daniel J. Wallace is one of the world's leading authorities on this disorder, an eminent clinician who has treated over 3000 lupus patients, the largest such practice in America. His The Lupus Book, originally published in 1995, immediately established itself as the most readable and helpful book on the disease. Now Dr. Wallace has once again completely revised The Lupus Book, incorporating a wealth of new information. This Fifth Edition discusses new drug information and newly discovered information about the pathology of the disease--all laid out in user-friendly language that any patient could understand. In particular, Wallace discusses the first drug for Lupus to be approved by the FDA--belimumab (Benlysta)--as well as other drugs in clinical trials. Readers will also discover fully updated sections on the science of lupus and breakthroughs in research. And as in past editions, the book provides absolutely lucid answers to such questions as: What causes lupus? How and where is the body affected? Can a woman with lupus have a baby? And how can one manage this disease? Indeed, Dr. Wallace has distilled his extensive experience, providing the most up-to-date information on causes, prevention, cure, exercise, diet, and many other important topics. There is also a glossary of terms and an appendix of lupus resource materials compiled by the Lupus Foundation of America. Over a million Americans have lupus. The new Fifth Edition offers these patients and their families an abundance of reliable, up-to-date information that will help them manage the disease and live a happier life.

Systemic Lupus Erythematosus

Systemic Lupus Erythematosus
Author : Jasper Meyer
Publisher : Unknown
Release Date : 2019-06-20
Category :
Total pages :212
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Systemic lupus erythematosus is a type of autoimmune disease. It is a chronic inflammatory condition in which the immune system mistakenly attacks the healthy tissues and body parts. The symptoms range from mild to severe. Fever, tiredness, painful and swollen joints, red rash on the face, mouth ulcers and swollen lymph nodes are some common symptoms. Genetic and environmental factors are believed to be its causes. Antinuclear antibody (ANA) testing, anti-extractable nuclear antigen (anti-ENA) and lupus band test are used for diagnosing it. Treatment methods include nonsteroidal anti-inflammatory drugs (NSAIDs), disease-modifying antirheumatic drugs (DMARDs), immunosuppressants and intravenous immunoglobulins (IVIGs). This book brings forth some of the most innovative concepts and elucidates the unexplored aspects of systemic lupus erythematosus. It will also provide interesting topics for research, which interested readers can take up. The extensive content of this book provides the readers with a thorough understanding of this disease.

Current Topics in Anemia

Current Topics in Anemia
Author : Jesmine Khan
Publisher : BoD – Books on Demand
Release Date : 2018-02-07
Category : Medical
Total pages :282
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This book deals with a very common condition, anemia, which might interest not only the physicians but also other healthcare professionals and researchers dealing with anemic patients. The objective of this book was to collect and compile up-to-date information from reputable researchers of different countries of the world to disseminate the latest information about the common types of anemia in some specific physiological and pathological conditions including pathophysiology and the use of algorithms as a tool to minimize the laboratory tests and accurate diagnosis of the underlying cause. In total, there are 13 chapters in this book where the authors shared their research findings and real-life experiences in managing their patients with anemia.

Autoimmune Bullous Diseases

Autoimmune Bullous Diseases
Author : Müzeyyen Gönül,Seray Çakmak
Publisher : BoD – Books on Demand
Release Date : 2018-05-09
Category : Medical
Total pages :256
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Autoimmune bullous diseases are a group of rare skin diseases characterized by intraepidermal and subepidermal bullae formations due to autoantibodies directed against the structural proteins of the epidermis or the dermal-epidermal junction. Early and correct diagnosis and adequate treatment of autoimmune bullous diseases are important as they cause morbidity and mortality in the affected patients. This book, which gives detailed information about autoimmune bullous diseases, has two sections and nine chapters with sixteen contributing authors. The first section describes the structure and tasks of desmosomes and basement membrane zone, which consist of the major antigens of skin integrity targeted by autoantibodies. The second section is about the epidemiology, etiopathogenesis, mucocutaneous, histopathologic and laboratory findings, and therapy of autoimmune bullous diseases.

Ferri's Clinical Advisor 2021 E-Book

Ferri's Clinical Advisor 2021 E-Book
Author : Fred F. Ferri
Publisher : Elsevier Health Sciences
Release Date : 2020-06-10
Category : Medical
Total pages :2176
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Find fast answers to inform your daily diagnosis and treatment decisions! Ferri’s Clinical Advisor 2021 uses the popular "5 books in 1" format to deliver vast amounts of information in a clinically relevant, user-friendly manner. This bestselling reference has been significantly updated to provide you with easy access to answers on 1,000 common medical conditions, including diseases and disorders, differential diagnoses, clinical algorithms, laboratory tests, and clinical practice guidelines—all carefully reviewed by experts in key clinical fields. Extensive algorithms, along with hundreds of new figures and tables, ensure that you stay current with today's medical practice. Contains significant updates throughout, covering all aspects of current diagnosis and treatment. Features 27 all-new topics including chronic rhinosinusitis, subclinical brain infarction, reflux-cough syndrome, radiation pneumonitis, catatonia, end-stage renal disease, and genitourinary syndrome of menopause, among others. Includes new appendices covering common herbs in integrated medicine and herbal activities against pain and chronic diseases; palliative care; and preoperative evaluation. Offers online access to Patient Teaching Guides in both English and Spanish.