January 25, 2021

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Systems Biology and Its Application in TCM Formulas Research

Systems Biology and Its Application in TCM Formulas Research
Author : Wei-Dong Zhang
Publisher : Academic Press
Release Date : 2018-02-16
Category : Medical
Total pages :380
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Systems Biology and Its Application in TCM Formulas Research presents a theoretical research system formed for Traditional Chinese Medicine (TCM) formulas, along with information on the study of Shexiang Baoxin Pill (SBP), a TCM formula that has shown significant clinical efficacy in the treatment of cardiovascular diseases. The content combines theory and practice, and includes guidance for both theoretical concepts and operable technical routes. This is a valuable source not only for biomedical researchers involved in Systems Biology studies, but also for students and scientists interested in learning more about Traditional Chinese Medicine and its applications in contemporary medicine. Explains, in detail, the Shexiang Baoxin Pill (SBP), a TCM formula efficiently applied in the treatment of cardiovascular diseases Presents TCM formulas from perspectives of systems biology, basic chemical material groups, modern pharmacology and network biology Offers an overview on biology, modern chemistry and information technology as applied in Systems Biology research

Systems Biology for Traditional Chinese Medicine

Systems Biology for Traditional Chinese Medicine
Author : Guoan Luo,Yiming Wang,Qingfei Liu,Qionglin Liang
Publisher : John Wiley & Sons
Release Date : 2012-07-03
Category : Medical
Total pages :490
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The application of systems biology methods to Traditional Chinese Medicine Emphasizing the harmony of the human body with the environment, Traditional Chinese Medicine (TCM) has evolved over thousands of years. It is a systemic theory derived from clinical experience, the philosophy of holism and systematology, and the belief that man is an integral part of nature. Systems Biology for Traditional Chinese Medicine describes how the latest methods in systems biology can be applied to TCM, providing a comprehensive resource for the modernization and advancement of TCM as well as general drug discovery efforts. It is the first comprehensive work to propose a system-to-system research methodology to study the interaction between TCM and the human body and its applications in drug research and development. Using three popular traditional Chinese medicines—Shuanglongfang, Qingkailing, and Liushenwan—as examples, the authors set forth case examples demonstrating how to find material groups, perform efficacy screenings, and conduct safety evaluations of TCM. The book also: Describes the mechanisms of TCM at the molecular and systems levels using chemomics, genomics, proteomics, metabolomics, and bioinformatics Places modern scientific technologies within the context of TCM, helping drug researchers improve experimental designs and strategies Illustrates how a systems biology approach is compatible with TCM's traditional, holistic therapeutic strategies and treatment modalities Presents topics of current interest, such as integrated global systems biology and the application of chemometrics research to herbal medicines This book not only opens a new pathway for the continued development of TCM, but also for systems biology. In addition, it fosters collaboration and discussion among Eastern and Western scientists by applying systems biology to TCM.

The Science and Regulations of Naturally Derived Complex Drugs

The Science and Regulations of Naturally Derived Complex Drugs
Author : Ram Sasisekharan,Sau L. Lee,Amy Rosenberg,Larry A. Walker
Publisher : Springer
Release Date : 2019-04-23
Category : Medical
Total pages :331
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This volume in the AAPS Advances series covers various quality, safety and clinical aspects of drug development that are relevant to new and/or generic drugs containing a complex mixture of molecules. Specific topics discussed include: raw materials sourcing; manufacturing controls; characterization; identification of critical product quality components and attributes; identification of impurities, particularly as they bear on toxicity and immunogenicity; clinical trial study design considerations, and the regulatory science applications to development of such complex mixtures. Complex mixtures are challenging to characterize and analyze using standard methods. Further challenges extend throughout the product development cycle from raw material control to clinical study design. The regulatory landscape is rapidly changing as new types of complex mixtures are introduced into clinical trials and to the market (e.g., traditional Chinese medicines and medical marijuana products), while older products are facing generic competition for the first time (e.g., enoxaparin). The future outlook for complex generic drug products, as opposed to the more commonly developed targeted single agent drug products is not clear. The risks pertaining to lack of a full understanding of raw material control, process and controls in manufacture, as well as characterization of a complex mixture were seen vividly during the heparin crisis of 2008. As such powerful lessons have been learned about the regulatory science specific to complex products. The Science and Regulations of Naturally Derived Complex Drugs addresses the interests among industry, academics, and government on the issues surrounding the future development of mixtures for medicinal use.

Intelligent Computing Theories and Application

Intelligent Computing Theories and Application
Author : De-Shuang Huang,Kang-Hyun Jo,Zhi-Kai Huang
Publisher : Springer
Release Date : 2019-09-22
Category : Computers
Total pages :790
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This two-volume set of LNCS 11643 and LNCS 11644 constitutes - in conjunction with the volume LNAI 11645 - the refereed proceedings of the 15th International Conference on Intelligent Computing, ICIC 2019, held in Nanchang, China, in August 2019. The 217 full papers of the three proceedings volumes were carefully reviewed and selected from 609 submissions. The ICIC theme unifies the picture of contemporary intelligent computing techniques as an integral concept that highlights the trends in advanced computational intelligence and bridges theoretical research with applications. The theme for this conference is “Advanced Intelligent Computing Methodologies and Applications.” Papers related to this theme are especially solicited, including theories, methodologies, and applications in science and technology.

Modern Computational Approaches to Traditional Chinese Medicine

Modern Computational Approaches to Traditional Chinese Medicine
Author : Zhaohui Wu,Huajun Chen,Xiaohong Jiang
Publisher : Elsevier
Release Date : 2012
Category : Medical
Total pages :233
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Recognized as an essential component of Chinese culture, Traditional Chinese Medicine (TCM) is both an ancient medical system and one still used widely in China today. TCM's independently evolved knowledge system is expressed mainly in the Chinese language and the information is frequently only available through ancient classics and confidential family records, making it difficult to utilize. The major concern in TCM is how to consolidate and integrate the data, enabling efficient retrieval and discovery of novel knowledge from the dispersed data. Computational approaches such as data mining, semantic reasoning and computational intelligence have emerged as innovative approaches for the reservation and utilization of this knowledge system. Typically, this requires an inter-disciplinary approach involving Chinese culture, computer science, modern healthcare and life sciences. This book examines the computerization of TCM information and knowledge to provide intelligent resources and supporting evidences for clinical decision-making, drug discovery, and education. Recent research results from the Traditional Chinese Medicine Informatics Group of Zhejiang University are presented, gathering in one resource systematic approaches for massive data processing in TCM. These include the utilization of modern Semantic Web and data mining methods for more advanced data integration, data analysis and integrative knowledge discovery. This book will appeal to medical professionals, life sciences students, computer scientists, and those interested in integrative, complementary, and alternative medicine. Interdisciplinary book bringing together Traditional Chinese Medicine and computer scientists Introduces novel network technologies to Traditional Chinese Medicine informatics Provides theory and practical examples and case studies of new techniques

Chinmedomics

Chinmedomics
Author : Xijun Wang,Aihua Zhang,Hui Sun
Publisher : Academic Press
Release Date : 2015-07-15
Category : Medical
Total pages :408
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Chinmedomics: The Integration of Serum Pharmacochemistry and Metabolomics to Elucidate the Scientific Value of Traditional Chinese Medicine uses new experimental techniques and research to open doors in drug discovery and development related to traditional Chinese medicine (TCM). This book features a unique approach that combines chemometric analysis with metabolomics studies to illuminate significant changes that have occurred in syndrome states while simultaneously analyzing the efficacy of chemical ingredients in herbal medicines. Chapters provide cutting-edge information on traditional medicine, analytical technology, natural products, metabolomics, bioinformatics and their applications. This book provides a valuable resource for pharmacologists, pharmaceutical scientists, medicinal plant researchers, pharmacognosists and chemists working with TCM and highlights ways to further research and advances in this area in the future. Presents a practical guide for new practitioners of Chinmedomics with insights on the current use and future development of this method Each chapter includes an introduction, method, references to the latest literature, possible mechanisms of action and applications Edited by the leading experts of research related to Chinmedomics

Essentials of Chinese Materia Medica and Medical Formulas

Essentials of Chinese Materia Medica and Medical Formulas
Author : Shengyan Xi,Yuewen Gong
Publisher : Academic Press
Release Date : 2017-05-01
Category : Medical
Total pages :1020
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Essentials of Chinese Materia Medica and Medical Formulas: New Century Traditional Chinese Medicine presents specific knowledge about the source, medicinal nature, action and application of more than 800 commonly-used Chinese materia medica, as well as the efficacy and application of more than 740 kinds of commonly-used Chinese medical formulas. Notably, all of the content is presented in table form, making the information easier to access, understand and apply. Each primary herbal medicine is introduced with color pictures, and each primary formula is presented with efficacy analysis pictures. The book provides readers with essential information on Chinese materia medica and formulas and how to use them accurately, including the most common Chinese materia medica used in clinics and in commonly used clinical formulas. This is an essential reference for traditional medical professionals and those interested in traditional Chinese medicine, including advanced undergraduate and postgraduate students. Includes over 800 Chinese materia medica and 740 medical formulas with their essential information Combines 514 color pictures of medicine material crude slices and 255 formulary efficacy analysis pictures Organized with concise forms, facilitating understanding and memorization

Nature

Nature
Author : Sir Norman Lockyer
Publisher : Unknown
Release Date : 2007-07
Category : Electronic journals
Total pages :129
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Complementary Therapies for the Body, Mind and Soul

Complementary Therapies for the Body, Mind and Soul
Author : Marcelo Saad
Publisher : BoD – Books on Demand
Release Date : 2015-09-02
Category : Medical
Total pages :296
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Complementary Therapies (CT) refers to the practices, products, or health systems that are outside the realm of conventional medicine, used to treat disease or to promote health and well-being. Defining CT is difficult, because the field is very broad and constantly changing. The title of this book includes the words body, mind, and soul. The body and the mind (and their reciprocal relations) have been extensively studied scientifically. What about the soul? The book brings some points about this new ground in CT. We hope you find in the present work the sincere desire to collaborate with the dissemination of knowledge. May this book be useful and pleasant to you.

Serum Pharmacochemistry of Traditional Chinese Medicine

Serum Pharmacochemistry of Traditional Chinese Medicine
Author : Xijun Wang,Aihua Zhang,Hui Sun
Publisher : Academic Press
Release Date : 2016-12-27
Category : Medical
Total pages :378
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Serum Pharmacochemistry of Traditional Chinese Medicine: Technologies, Strategies and Applications provides a valuable and indispensable guide on the latest methods, research advances, and applications in this area. Chapters offer cutting-edge information on pharmacokinetics and pharmacodynamics, analytical chemistry, traditional medicine, natural products, bioinformatics, new technologies, therapeutic applications, and more. For researchers and students in academia and industry, this book provides a hands-on description of experimental techniques, along with beneficial guidelines to help advance research in the fields of Traditional Chinese Medicine and drug development. Provides a valuable guide for practitioners of serum pharmacochemistry of Traditional Chinese Medicine, along with insights to its current use and future applications Edited and written by leading scientists at the forefront of this research Presents well written chapters that include an introduction, description of the method, and identification of chemical constituents, with applications and references to the latest research and literature

Essentials of Traditional Chinese Medicine

Essentials of Traditional Chinese Medicine
Author : Bing Ouyang,Zhen Gu,Lu, Yubin
Publisher : Jinan, China : Shandong Science and Technology Press
Release Date : 1996
Category : Medicine, Chinese
Total pages :215
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Antioxidants in Foods and Its Applications

Antioxidants in Foods and Its Applications
Author : Emad Shalaby,Ghada Mostafa Azzam
Publisher : BoD – Books on Demand
Release Date : 2018-07-11
Category : Health & Fitness
Total pages :178
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Free radicals are atoms or molecules containing unpaired electrons. Damage occurs when the free radical encounters another molecule and seeks to find another electron to pair its unpaired electron. Free radicals can cause mutation in different biological compounds such as protein, nucleic acids, and lipids, and the damage caused by the free radicals lead to various diseases (cancer, cardiovascular disease, aging, etc.). Antioxidants are helpful in reducing and preventing damage from free radical reactions because of their ability to donate electrons, which neutralize the radical without forming another. Ascorbic acid, for example, can lose an electron to a free radical and remain stable itself by passing its unstable electron around the antioxidant molecule. Unfortunately, new data indicate that the synthetic antioxidants used in the industry could have carcinogenic effects on human cells, thus fueling an intense search for new, natural, and efficient antioxidants. Therefore, the current book discusses the role and source of antioxidant compounds in nutrition and diets. Also, the current book includes nine chapters contributed by experts around the world, and the chapters are categorized into two sections: "Antioxidant Compounds and Biological Activities" and "Natural Antioxidants and Applications."

Herbs and Natural Supplements Inkling

Herbs and Natural Supplements Inkling
Author : Lesley Braun,Marc Cohen
Publisher : Elsevier Health Sciences
Release Date : 2010-06-24
Category : Medical
Total pages :900
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A must-have health companion for herbalists, naturopaths, complementary medicine practitioners and students Herbs and Natural Supplements, 3rd Edition: An evidence-based guide presents evidence-based information on the 130 most popular herbs, nutrients and food supplements used across Australia and New Zealand. This exhaustive textbook is organised alphabetically by each herb or nutrient’s common name. Herbs and nutrients are then accompanied by critical information such as daily intake, main actions and indications, adverse reactions, contraindications and precautions, safety in pregnancy and more. This new edition of Herbs and Natural Supplements has been expanded with new chapters on pregnancy and wellness. It also features 10 new monographs for Arginine, Dunaliella, Elde, Goji, Pelargonium, Prebiotics, Red Yeast Rice, Rhodioloa, Shatavari and Taurine. • provides current, evidence-based information on herbal, nutritional and food supplements used in Australia and New Zealand • is user-friendly and easily organised by easy-to-find A-Z herbal monographs • appendices offering important additional information for the safe use of herbal and nutritional supplements, including a list of poison information centres, associations, manufacturers and more • offers clear, comprehensive tables including herb/natural supplement - drug interactions • lists the pharmacological actions of all herbs and natural supplements • a glossary of terms relevant to herbs and natural supplements • two comprehensive new chapters: Herbs and Natural Supplements in Pregnancy and Introduction to Wellness • all chapters completely updated and expanded • ten new monographs taking the total to 130 • now also available as an eBook! A code inside Herbs and Natural Supplements, 3rd Edition: An evidence-based guide enables a full text download, allowing you to browse and search electronically, make notes and bookmarks in the electronic files and highlight material

Eat to Beat Disease

Eat to Beat Disease
Author : William W Li
Publisher : Grand Central Publishing
Release Date : 2019-03-19
Category : Health & Fitness
Total pages :496
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Discover the new science of how eating can enable your body to heal itself from cancer, dementia, and dozens of avoidable diseases. Eat your way to better health with this New York Times bestseller. We have long radically underestimated our body's power to transform and restore our health. Pioneering physician scientist, Dr. William Li, empowers readers by showing them the evidence behind over 200 health-boosting foods that can starve cancer, reduce your risk of dementia, and beat dozens of avoidable diseases. This book isn't about what foods to avoid, but rather is a life-changing guide detailing the hundreds of healing foods you can add to your meals that support the body's defense systems, including: Plums Cinnamon Sourdough breadRed wine and beer Black Beans San Marzano tomatoes Olive oil Cheeses like Jarlsberg, Camembert and cheddar With Dr. Li's plan, the foods you already love can be optimized to activate your body's five natural health defense systems--Angiogenesis, Regeneration, Microbiome, DNA Protection, and Immunity--to fight cancer; diabetes; cardiovascular, neurodegenerative, and autoimmune diseases; and other debilitating conditions. Both informative and practical, Eat to Beat Disease explains the science of healing and prevention, strategies for using food to actively boost health, and points the study of well-being and disease recovery in an exhilarating new direction.

Chinese Herbal Formulas and Applications

Chinese Herbal Formulas and Applications
Author : John K. Chen,Tina T. Chen
Publisher : AOM Press
Release Date : 2009-01-01
Category : Materia medica
Total pages :1622
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Companion volume to Chinese Medical Herbology and Pharmacology. This book takes the next step in presenting not only the traditional usage of Chinese herbal formulas, but a combined perspective of the pharmacological effects of formulas themselves with clinically relevant research evidence. As competencies in multiple health care disciplines continue to be raised the need for integrative understandings rise with it. Chinese Herbal Formulas and Applications brings together Chinese Herbal Medicine and expands this with the pharmaceutical effects and clinical research findings to use herbal medicines exclusively or in combination with the allopathic medicine. Enhancing the understanding of herbs and herbal formulas from multiple perspectives, Chinese Herbal Formulas and Applications is a resource for improved patient care and therapeutic outcome. OUTSTANDING FEATURES: Comprehensive explanation of the pharmacology of herbal medicinal formulas, and concurrent uses of herbal formulas and pharmaceuticals Documentation from clinical studies and published research Profiles of the doctors without whom there would be no Chinese medicine: insights into the historical context and backgrounds of those famous individuals who shaped our understanding of disease patterns, treatment strategies and herbal formulas. Contributions from over 100 academic, clinical, research and regulatory professionals who reviewed the text before publication, to complement the work of the authors. PLUS Detailed traditional and modern uses, preparation, administration, dosages, combinations, cautions, contraindications and toxicology. Authors comments are drawn from clinical experience. Appendices on herbal medicine for pregnancy and postpartum care and much more.