June 12, 2021

Download Ebook Free The Neurobiology Of Bipolar Disorder

Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder
Author : Joao Quevedo,Andre Ferrer Carvalho,Eduard Vieta
Publisher : Academic Press
Release Date : 2020-11-25
Category : Medical
Total pages :470
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The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Bipolar Disorder

Bipolar Disorder
Author : Lakshmi N. Yatham,Mario Maj
Publisher : John Wiley & Sons
Release Date : 2011-06-28
Category : Psychology
Total pages :522
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Bipolar disorder is the most complex psychiatric disorder with different types of mood episodes, subtypes, varied course, and significant co-morbidity. Not surprisingly, this complexity poses unique challenges to clinicians for optimal management of those with bipolar disorder. There has been an explosion of research into the causes and treatment of this condition over the past two decades. It is a daunting task for a practising clinician to make sense of this research and to remain up to date with progress in the understanding of the neurobiology and treatment of bipolar disorder. This book synthesizes and translates the vast array of research knowledge into information that is clinically relevant and meaningful for a clinician. The book provides a comprehensive, yet focused, reference work on bipolar disorder for both trainees and practising psychiatrists. The two editors are leaders in the field who have published extensively on bipolar disorder. They have assembled a team of experts from around the world: in many instances, chapters are co-authored by people from different continents, bringing a truly international perspective to this important topic. The book covers the basic science of the pathology underlying bipolar disorder but addresses the clinical aspects of the disease throughout. The book comprises four sections: Descriptive Aspects—issues ranging from how the concept of bipolar disorder has evolved over the years to new information about neurocognitive impairment, creativity and economic productivity, and to discussion of the deliberations of the DSM-V committee on changes in diagnostic categories and criteria. Biology—the contribution of genes to this disorder, changes in circadian rhythms, what we know about brain changes and the role of oxidative stress. Biological Treatment and Psychosocial Treatment— all the latest information about pharmacological and psychological treatments and the optimal management of this condition. If you want to provide state-of-the-art care to your bipolar patients, be sure to consult this authoritative reference.

Behavioral Neurobiology of Bipolar Disorder and its Treatment

Behavioral Neurobiology of Bipolar Disorder and its Treatment
Author : Husseini K. Manji,Carlos A. Zarate Jr.
Publisher : Springer Science & Business Media
Release Date : 2010-11-10
Category : Medical
Total pages :347
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This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Bipolar Disorder in Youth

Bipolar Disorder in Youth
Author : Stephen M. Strakowski
Publisher : Oxford University Press, USA
Release Date : 2014-10-29
Category : Medical
Total pages :400
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Bipolar disorders affect up to 3% of the world's population and are the 6th leading cause of disability worldwide. The estimated annual costs of bipolar disorder approach $50 billion in the United States, and the associated societal and personal suffering is immeasurable. Bipolar disorder is a lifelong illness that typically begins in mid-adolescence, thereby disrupting healthy developmental processes. It is also a progressive illness, making early intervention even more critical. As the disorder presents differently in youth as it does in adults, considerable controversy exists around the diagnosis in young people. The neurobiological factors leading to the onset of bipolar disorder reflect abnormalities in adolescent brain development. Bipolar disorder is strongly heritable and therefore, these developmental abnormalities likely represent the culmination of processes that precede the expression of symptoms. Current studies of children who are at risk for bipolar disorder are identifying these processes. Again, controversy exists about how to move these neuroscience gains forward to help affected individuals and, particularly to manage children at risk to delay or prevent the onset or progression of bipolar disorder. With these considerations in mind, Bipolar Disorder in Youth provides a timely, focused review of the diagnosis, treatment, and neurobiology of bipolar disorder in youth. It addresses current controversies and resolves those in which evidence is available. The book is organized into three sections based on these topics to provide comprehensive discussions to aid clinicians managing these individuals in their practices, as well as scientists trying to advance the field. The three editors are widely recognized experts in bipolar disorder, and the authors of each chapter represent international experts in the respective topics. Consequently, this book is the most comprehensive volume available discussing this important population and is a 'must' for the libraries of clinicians and scientists working with bipolar children and adolescents.

The Neurobiology of Bipolar Disorder in Young People

The Neurobiology of Bipolar Disorder in Young People
Author : Rebecca A. Chandler
Publisher : Unknown
Release Date : 2009
Category :
Total pages :129
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Behavioral Neurobiology of Bipolar Disorder and its Treatment

Behavioral Neurobiology of Bipolar Disorder and its Treatment
Author : Husseini K. Manji,Carlos A. Zarate Jr.
Publisher : Springer
Release Date : 2011-04-08
Category : Medical
Total pages :347
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This book offers the most up-to-date information about research surrounding the neurobiology of bipolar disorder as well as currently available and novel therapeutic options. The volume has assembled a widely respected group of preclinical and clinical researchers who bring their expertise to bear upon this illness by reviewing cutting-edge research and clinical evidence regarding the pathophysiology and treatment of bipolar disorder. Early chapters review the course and outcome and genetics of this highly heritable condition, including chapters on epigenetics and clinical endophenotypes. Several chapters offer a remarkably thorough and unique overview of the neurobiology of the disorder, including what is known from neuroimaging work and the development of animal models. Finally, the book covers treatment strategies for bipolar disorder, including both traditional and novel therapeutics, as well as non-pharmacological treatments. It offers both researchers and clinicians key insights into this devastating disorder.

Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy

Bipolar Depression: Molecular Neurobiology, Clinical Diagnosis, and Pharmacotherapy
Author : Carlos A. Zarate Jr.,Husseini K. Manji
Publisher : Springer
Release Date : 2017-01-28
Category : Medical
Total pages :371
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This book brings together mental health professionals and researchers to offer the most up-to-date information on the diagnosis, treatment, and research surrounding bipolar depression. Its individual chapters provide valuable diagnostic information, allowing clinicians to distinguish between the various mood disorders. Further, they: review the course, outcome, and genetics of this highly heritable condition; offer a thorough overview of the neurobiology of the disorder, including what is known from neuroimaging work; delineate the treatment of bipolar depression in special populations such as children and pregnant women; address suicide, focusing on the need for assessment during both acute and maintenance treatment with interventions appropriate to a patient’s symptoms and history; and cover acute and long-term treatment strategies for bipolar depression, including both traditional and novel therapeutics for the disorder, as well as non-pharmacological treatments. This second edition reflects significant advances, including an improved understanding of the altered neurobiology of patients suffering from bipolar depression, new information on pathophysiology and genetic findings drawn from diverse studies, and a discussion of the significant strides made towards improved treatment with already available and novel agents.

Bipolar Disorder: From Neuroscience to Treatment

Bipolar Disorder: From Neuroscience to Treatment
Author : Allan H. Young,Mario F. Juruena
Publisher : Springer
Release Date : 2021-03-30
Category : Medical
Total pages :325
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Bipolar disorder is a common, complex and costly mental health disorder, which sits at the heart of the practice of clinical psychiatry. Effective treatments (pharmacological, psychological and brain stimulation based) have all been discovered serendipitously. With the huge advances in basic neuroscience the way is now clear for novel treatments to be developed based on brain science. This book reviews these possibilities.

The Bipolar Book

The Bipolar Book
Author : Aysegul Yildiz,Pedro Ruiz,Charles Nemeroff
Publisher : Oxford University Press
Release Date : 2015-05-22
Category : Medical
Total pages :720
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As a major mainstay of clinical focus and research today, bipolar disorder affects millions of individuals across the globe with its extreme and erratic shifts of mood, thinking and behavior. Edited by a team of experts in the field, The Bipolar Book: History, Neurobiology, and Treatment is a testament and guide to diagnosing and treating this exceedingly complex, highly prevalent disease. Featuring 45 chapters from an expert team of contributors from around the world, The Bipolar Book delves deep into the origins of the disorder and how it informs clinical practice today by focusing on such topics as bipolar disorder occurring in special populations, stigmatization of the disease, the role genetics play, postmortem studies, psychotherapy, treatments and more. Designed to be the definitive reference volume for clinicians, students and researchers, Ayseg?l Yildiz, Pedro Ruiz and Charles Nemeroff present The Bipolar Book as a "must have" for those caregivers who routinely deal with this devastating disease.

Bipolar Disorders

Bipolar Disorders
Author : Gershon Samuel,Jair C. Soares
Publisher : CRC Press
Release Date : 2000-04-25
Category : Medical
Total pages :600
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Responding to the explosion of research on the pathophysiology and management of bipolar disorder, this completely revised Second Edition spans basic mechanisms, neuroimaging, viral etiology, neurofactors, current treatment implications, and modern theories of the neurobiology of bipolar disorder to stand as the most authoritative reference on this

Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders
Author : Thomas E. Schlaepfer,Charles B. Nemeroff
Publisher : Elsevier
Release Date : 2012
Category : Medical
Total pages :760
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This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Neurobiology of Mental Illness

Neurobiology of Mental Illness
Author : Dennis S. Charney,Eric J. Nestler,Pamela Sklar,Joseph D. Buxbaum
Publisher : Oxford University Press
Release Date : 2013-07-04
Category : Medical
Total pages :1222
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Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Bipolar Disorders

Bipolar Disorders
Author : Gershon Samuel,Jair C. Soares
Publisher : CRC Press
Release Date : 2000-04-25
Category : Medical
Total pages :600
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Responding to the explosion of research on the pathophysiology and management of bipolar disorder, this completely revised Second Edition spans basic mechanisms, neuroimaging, viral etiology, neurofactors, current treatment implications, and modern theories of the neurobiology of bipolar disorder to stand as the most authoritative reference on this debilitating condition. Written and edited by internationally lauded experts in the field, this source covers an expansive array of topics including genetic and causal factors, neuroendocrinology, neurotransmitters and signal transduction pathways, neuroimaging and neurorecognition, and prospects for new treatment development.

Bipolar Disorder: From Neuroscience to Treatment

Bipolar Disorder: From Neuroscience to Treatment
Author : Allan H. Young
Publisher : Springer Nature
Release Date : 2021
Category :
Total pages :129
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Bipolar Depression

Bipolar Depression
Author : Rif S. El-Mallakh,S. Nassir Ghaemi
Publisher : American Psychiatric Pub
Release Date : 2007-04-02
Category : Medical
Total pages :277
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Although depression is the most common presentation of bipolar disorder, correct diagnosis generally requires a history of mania and thus presents a formidable challenge. This book provides clinicians with the necessary guidance to distinguish this illness and pursue an appropriate therapeutic course. It brings together a team of clinical investigators who offer cutting-edge research on the topic and address the most critical concerns regarding its treatment. Bipolar Depression first introduces a hierarchical model for diagnosis to allow the clinician to distinguish between bipolar and unipolar depression, addressing problems of misdiagnosis and overdiagnosis as well as differentiating attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder. Early chapters review the neurobiology and genetics of this highly heritable condition, presenting studies of neurotransmitter function and brain imaging studies and documenting the susceptibility of specific chromosomes as loci for bipolar disorder. Other chapters address the particular issues of bipolar depression in children, for whom a diagnosis is especially problematic, and suicide, focusing on the need for assessment during both acute and maintenance treatment with interventions appropriate to a patient's symptoms and history. Bipolar Depression offers critiques of specific treatment approaches: Lithium and antiepileptic drugs: featuring a review of the most recent research on the use of lithium, in which higher doses are shown to be effective, plus coverage of lamotrigine, valproic acid, carbamazepine, oxcarbazepine, and topiramate. Antidepressants: offering new perspectives on a complex field, including a discussion of the randomized clinical trial literature and observational studies on their use, and citing cautions regarding side effects. Antipsychotics: evaluating the difference between first- and second-generation medications and discussing their role in controlling acute depressions. Novel approaches to treatment: including the use of atypical neuroleptics, electroconvulsive therapy, transcranial magnetic stimulation, vagus nerve stimulation, ketogenic diet, omega-3 fatty acids, myo-inositol, and dopamine agonists. Psychological interventions: focusing on the inclusion of cognitive-behavioral therapy or interpersonal social rhythm therapy for nonmelancholic depressions in patients who had previously received psychoeducation. Despite the past decade's advances in practice and research, there remains much room for progress in understanding and treating bipolar depression. This book blazes a trail toward that goal, opening new doors in recognizing differences between bipolar and unipolar forms of depression while offering both researchers and clinicians key insights into this troubling illness.