June 13, 2021

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Translational Inflammation

Translational Inflammation
Author : Anonim
Publisher : Academic Press
Release Date : 2018-11-24
Category : Medical
Total pages :294
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Translational Inflammation links laboratory and clinical data within primary and secondary care to clinical research data and offers a holistic and innovative approach to chronic inflammation and ageing. Understanding the role of inflammation as a part of clinical disease states is becoming a valuable tool in both direct treatment and the development of therapeutics. Translational Inflammation, the 4th volume in the Perspectives in Translational Cell Biology series, offers content for professors, students and researchers across basic and translational biology. Emphasizes the role of inflammation in disease and therapeutic approaches Integrates broad concepts relating inflammation to other fields Offers a bridge to review literature and primary research on the inflammatory response towards medical application

Translational Studies on Inflammation

Translational Studies on Inflammation
Author : Ane C.F. Nunes
Publisher : BoD – Books on Demand
Release Date : 2020-01-08
Category : Medical
Total pages :248
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Inflammation is known worldwide, from the bench to the bedside, but it is a hard theme to approach with one single point of view.In this sense, a selection of translational studies would support the medical-scientific community to better understand the complex network of the inflammatory process, its maintenance, and potential treatment targets. The eleven chapters that compose this book present interesting insights into inflammation and its mechanisms, merging classic background with innovative approaches. From the molecular basis to experimental models, the chapters selected for this book bring to readers at different academic levels updated and practical data on inflammation. Find out what drives interdisciplinary medical research on inflammation and enjoy this informative collection.

Perspectives in Translational Research in Life Sciences and Biomedicine

Perspectives in Translational Research in Life Sciences and Biomedicine
Author : Ena Ray Banerjee
Publisher : Springer
Release Date : 2016-05-27
Category : Science
Total pages :270
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The present book addresses the multi-disciplinary nature of Translational Outcomes Research, which is a watershed for nearly all the disciplines of Life and Health Sciences, along with the Materials Sciences including but not limited to Zoology, Botany, Microbiology, Biochemistry, Physiology, Nanotechnology, the Medical Sciences, Bioengineering, Biophysics, Medicinal Chemistry, Structural Biology, Biostatistics and Bioinformatics. This book, for the first time, addresses the basic premises of fundamental research in facilitating drug discovery. One chapter is dedicated to a novel generation of platforms with novel camelid antibodies and their technological extensions, while another focuses on functional food and nutraceuticals. The book begins with a thorough overview of what translational outcomes research connotes and what the current status of research in the area is, and goes on to elucidate various pertinent preclinical disease models and their uses in basic and application based research in the Life Sciences. How basic approaches to screening and characterization vis-à-vis their role in amelioration of the two cardinal problems of inflammation and degeneration involved in most diseases is elucidated. The book ends with a discussion of the relevance and importance of using Bio Green technology in Translational Outcomes, addressing the need to fill the gap between academia and industry and clinics that can arise through direct or indirect collaboration between the stakeholders and emphasizing the need for an eco-friendly approach so as not to jeopardize the fine balance that holds life on earth in harmony.

Neuroimmune Mechanisms in Chronic Inflammation

Neuroimmune Mechanisms in Chronic Inflammation
Author : Johanna Estelius
Publisher : Unknown
Release Date : 2018
Category :
Total pages :129
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MFG-E8 and Inflammation

MFG-E8 and Inflammation
Author : Ping Wang
Publisher : Springer Science & Business Media
Release Date : 2014-03-31
Category : Medical
Total pages :198
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After the discovery of milk fat globule-epidermal growth factor-factor 8 (MFG-E8) about two decades ago, a new era of delineating its potential beneficial role in several inflammatory diseases has begun to spout from the bench to translational research. In MFG-E8 and Inflammation, the editor and contributors have gathered a remarkable collection covering novel discoveries on the rapidly growing field of MFG-E8 and Inflammation which includes not only the findings from their individual lobotomies, but also from a host of pioneering researchers of this field. MFG-E8 and Inflammation starts by describing the origin, structure, expression, functions and regulation of MFG-E8, and then continues thoughtfully exploring its potentiality as a marker for apoptotic, stressed and activated cells. The topics cover the cellular and physiological function of MFG-E8, especially its role in efficient phagocytosis of apoptotic cells, intestinal barrier function, blood cell homeostasis and coagulation, and in the maintenance of the intact vascular system. The role of MFG-E8 in macrophages, neutrophils, lymphocytes, dendritic cells, platelets, as well as non-hematopoietic cells is adequately described in the book. The chapters also contain several lucid discussions on the recent discoveries of the roles of MFG-E8 in the autoimmune diseases, sepsis, tissue ischemia-reperfusion, hemorrhage, inflammatory bowel diseases, acute lung injury, asthma, lung fibrosis, stroke, prion diseases and Alzheimer’s diseases with the potential focus on elucidating novel mechanistic pathways. MFG-E8 and Inflammation is an indispensable resource for scientists and clinical researchers working on fundamental or applied aspects of MFG-E8 pathobiology. This book explores, dissects and reviews several noteworthy findings and striking future perspectives which not only rewrite the disease pathophysiology, but also update our understanding towards attaining novel therapeutic potentials against various inflammatory diseases.

Perspectives in Translational Research in Life Sciences and Biomedicine

Perspectives in Translational Research in Life Sciences and Biomedicine
Author : Ena Ray Banerjee
Publisher : Springer
Release Date : 2017-10-17
Category : Science
Total pages :132
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This book is a collation of translational research outcomes in the area of life research, which was formerly used mainly for academic pursuits. The studies described focus on innovative interdisciplinary approaches to unraveling problems in life sciences and biomedicine using biodiversity exploration and green technology. The techniques and models presented offer a ready reckoner for researchers in academic institutions and industry, and also provide valuable insights into fundamental research. The book discusses topics such as tissue engineering to create lineage-specific cells for tissue-specific regeneration; how combination cultures of commensalistic bacteria can help boost immunity; development of functional food from natural products from plant, animal, and microbial sources in the nutraceuticals domain; as well as synthesis and mechanisms in nanomedicine and nanoscaffolds in biomedicine. The studies and discourses described touch upon topics that explore biodiversity for the development of disease models, toxicity studies, developmental studies, and harvesting of bioactive compounds for alternative income generation and poverty alleviation, and as a result, bring about economic and ecologic sustainability. This multidimensional and multidisciplinary book focuses on tissue-specific targeting by nanodrugs, development of bioengineering formats for cell- based, nutraceutical-based, functional-food-based and antibody-based green therapy designed tackle multifaceted diseases and syndromes.

Xenobiotics and Inflammation

Xenobiotics and Inflammation
Author : Lawrence B. Schook,Debra L. Laskin
Publisher : Unknown
Release Date : 1994
Category : Medical
Total pages :361
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Emphasis is on the roles of cytokines and growth factors in the inflammatory process and how production of these mediators is modified by xenobiotics. Researchers exploring cell growth, angiogenesis, hematopoetic differentiation, and recruitment to and proliferation of cells in various tissue sites will find this book timely and useful. The editors have brought together experts in inflammation, cytokines, cell growth, immunology, and toxicology to provide a highly useful volume.

Translational Systems Biology

Translational Systems Biology
Author : Yoram Vodovotz,Gary An
Publisher : Elsevier
Release Date : 2014-10-08
Category : Science
Total pages :178
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Are we satisfied with the rate of drug development? Are we happy with the drugs that come to market? Are we getting our money’s worth in spending for basic biomedical research? In Translational Systems Biology, Drs. Yoram Vodovotz and Gary An address these questions by providing a foundational description the barriers facing biomedical research today and the immediate future, and how these barriers could be overcome through the adoption of a robust and scalable approach that will form the underpinning of biomedical research for the future. By using a combination of essays providing the intellectual basis of the Translational Dilemma and reports of examples in the study of inflammation, the content of Translational Systems Biology will remain relevant as technology and knowledge advances bring broad translational applicability to other diseases. Translational systems biology is an integrated, multi-scale, evidence-based approach that combines laboratory, clinical and computational methods with an explicit goal of developing effective means of control of biological processes for improving human health and rapid clinical application. This comprehensive approach to date has been utilized for in silico studies of sepsis, trauma, hemorrhage, and traumatic brain injury, acute liver failure, wound healing, and inflammation. Provides an explicit, reasoned, and systematic approach to dealing with the challenges of translational science across disciplines Establishes the case for including computational modeling at all stages of biomedical research and healthcare delivery, from early pre-clinical studies to long-term care, by clearly delineating efficiency and costs saving important to business investment Guides readers on how to communicate across domains and disciplines, particularly between biologists and computational researchers, to effectively develop multi- and trans-disciplinary research teams

Canadian Journal of Biochemistry

Canadian Journal of Biochemistry
Author : Anonim
Publisher : Unknown
Release Date : 1982
Category : Biochemistry
Total pages :129
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Complex Systems and Computational Biology Approaches to Acute Inflammation

Complex Systems and Computational Biology Approaches to Acute Inflammation
Author : Yoram Vodovotz
Publisher : Springer Nature
Release Date : 2021
Category :
Total pages :129
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Inflammation and Gastrointestinal Cancers

Inflammation and Gastrointestinal Cancers
Author : Janusz A. Z. Jankowski
Publisher : Springer Science & Business Media
Release Date : 2011-08-08
Category : Medical
Total pages :202
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Inflammation in gastrointestinal mucosa can remodel the topography of the overlying epithelium. If such inflammation is chronic, it has fundamental clinical consequences, the principal of which is premalignant metaplasia throughout the alimentary tract. Furthermore, mucosal inflammation, even if subtle, is the single most common pathway for GI cancer. This book discusses all aspects of the relation between inflammation and GI cancer, from the basic science through to the translational science which is helping in the optimization of clinical management strategies. Among the topics considered are the impact of inherited syndromes; the roles of acid reflux, H. pylori, inflammatory bowel disease, and primary sclerosing cholangitis; screening strategies; targeted drug therapies; genetics; and the use of endoscopic methods. The authors are the best in their field, and this book is designed for the enthusiastic student as well as the professional in GI science and medicine.

Iron in Immunity, Cancer and Inflammation

Iron in Immunity, Cancer and Inflammation
Author : Maria de Sousa,Jeremy H. Brock
Publisher : John Wiley & Sons Incorporated
Release Date : 1989-08-15
Category : Medical
Total pages :415
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This collection of articles considers several traditional areas of interest in iron metabolism, such as absorption and the red cell cycle, in relation to inflammation, cancer, and immunity. Considers implications for diagnosis and treatment.

The Pain System in Normal and Pathological States

The Pain System in Normal and Pathological States
Author : Luis Villanueva,A. H. Dickenson,H. Ollat
Publisher : International Assn for the Study of Pain
Release Date : 2004
Category : Medical
Total pages :347
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The last decade has seen much progress in understanding the mechanisms of pain and advances in basic science have seen translational research leading to volunteer studies and clinical trials. Despite this drawing together of molecules and maladies, the basic science can appear overly complex and impenetrabie for clinicians. This book aims to cover key topical molecular, anantomical, physiological, and pharmacological studies on the basic science in a straightforward and accessible manner for all medical and allied professionals with an interest in pain. The book is dedicatod to lean-Marie Besson, who has always allempted to further dialogus between clinicians and basic scientists.

Inflammation: Mechanisms and Therapeutics

Inflammation: Mechanisms and Therapeutics
Author : Niall S. Doherty,Barry M. Weichmann,Douglas W. Morgan,Lisa A. Marshall
Publisher : Birkhäuser
Release Date : 1995-03-27
Category : Medical
Total pages :214
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The Seventh International Conference of the Inflammation Research Association, entitled "Inflammation, Mechanisms and Therapeutics" was held on September 25-29,1994 in White Haven, Pennsylvania. The major focus of this series of conferences is the multidisciplinary investigation of inflammation and the discovery of novel therapeutic approaches to inflammatory diseases. It was therefore particularly gratifying that the list of attendees included scientists of diverse backgrounds - preclinical biology, synthetic and theoretical chemistry, biotechnology and clinical research. The Conference was characterized by a very high degree of participation in the scientific debate by attendees, a large proportion of whom presented at poster sessions, poster discussions and workshops, and by the many opportunities for informal discussion provided by the organizers. This volume captures much of the excitement and enthusiasm of the Conference and should be a valuable resource for scientists in the field. Niall S. Doherty Barry M. Weichman Douglas W. Morgan Lisa A. Marshall IX Acknowledgments The manuscripts contained in this volume are based on material presented at the Seventh International Conference of the Inflammation Research Association held in White Haven, Pennsylvania, on September 25-29,1994. We would like to thank the speakers and session chairpersons for their contributions to the Conference and these Proceedings. The following individuals played indispensable roles in the organization and running of the Conference and are responsible for making it such a success: PLANNING SCHOLARSHIP Niall S. Doherty Janet Kerr, Chairperson Barry M. Weichman Richard Carlson Douglas Morgan Richard Harris Loran Killar D.

Handbook of Inflammation

Handbook of Inflammation
Author : Anonim
Publisher : Unknown
Release Date : 1983
Category : Inflammation
Total pages :129
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