November 24, 2020

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Volatile Biomarkers

Volatile Biomarkers
Author : Anton Amann,David Smith
Publisher : Newnes
Release Date : 2013-03-27
Category : Science
Total pages :600
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Volatile organic compounds (VOCs) in exhaled breath, sweat or urine carry much information on the state of human health. The role of VOCs in clinical diagnosis and therapeutic monitoring is expected to become increasingly significant due to recent advances in the field. Volatile Biomarkers: Non-Invasive Diagnosis in Physiology and Medicine includes the latest discoveries and applications for VOCs from the world's foremost scientists and clinicians working in this emerging analytic area. Appeals to a multidisciplinary audience, including scientists, researchers, and clinicians with an interest in breath analysis Features the latest scientific research and technical breakthroughs in the diagnostic and therapeutic aspects of volatile organic compounds Includes case presentations documenting applications in multiple areas of human health and safety

Analysis of Volatile Biomarkers from in Vitro Cell Cultures and Exhaled Breath for Ventilator-associated Pneumonia Diagnosis

Analysis of Volatile Biomarkers from in Vitro Cell Cultures and Exhaled Breath for Ventilator-associated Pneumonia Diagnosis
Author : Oluwasola Lawal
Publisher : Unknown
Release Date : 2019
Category :
Total pages :129
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The Handbook of Biomarkers

The Handbook of Biomarkers
Author : Kewal K. Jain
Publisher : Springer Science & Business Media
Release Date : 2010-02-06
Category : Medical
Total pages :492
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Of the thousands of biomarkers that are currently being discovered, relatively few are being validated for further applications, and the potential of a biomarker can be quite difficult to evaluate. To aid in this imperative research, Dr. Kewal K. Jain’s Handbook of Biomarkers thoroughly describes many different types of biomarkers and their discovery using various "-omics" technologies, such as proteomics and metabolomics, along with the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials. With biomarkers described first according to technologies and then according to various diseases, this detailed book features the key correlations between diseases and classifications of biomarkers, which provides the reader with a guide to sort out current and future biomarkers. Comprehensive and cutting-edge, The Handbook of Biomarkers serves as a vital guide to furthering our understanding of biomarkers, which, by facilitating the combination of therapeutics with diagnostics, promise to play an important role in the development of personalized medicine, one of the most important emerging trends in healthcare today.

Biomarkers in Allergy and Asthma, An Issue of Immunology and Allergy Clinics of North America E-Book

Biomarkers in Allergy and Asthma, An Issue of Immunology and Allergy Clinics of North America E-Book
Author : Flavia Hoyte,Rohit K. Katial
Publisher : Elsevier Health Sciences
Release Date : 2018-10-23
Category : Medical
Total pages :129
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This issue of Immunology and Allergy Clinics, guest edited by Drs. Flavia Hoyte and Rohit Katial, is devoted to Biomarkers in Allergy and Asthma. Articles in this issue include: Exhaled Nitric Oxide; Biomarkers in Exhaled Breath Condensate (EBC); Role of Eosinophils in Asthma; Bronchoprovocation Testing in Asthma; Periostin and DPP4; Role of Neutrophils in Asthma; Urinary LTE4; Biomarkers in Nasal Polyps; IgE as a Biomarker in Asthma; Genetics of Asthma; and Biomarker-directed Therapies for Asthma.

Update on Biomarkers in Allergy and Asthma, An Issue of Immunology and Allergy Clinics

Update on Biomarkers in Allergy and Asthma, An Issue of Immunology and Allergy Clinics
Author : Rohit Katial
Publisher : Elsevier Health Sciences
Release Date : 2012-10-22
Category : Medical
Total pages :120
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This issue of Immunology and Allergy Clinics provides a comprehensive review of the current state of biomarkers and their role in the asthma diagnostic and therapeutic algorithm.Since the last issue on Biomarkers, which published in 2007, significant research directly targeted at biomarker development and clinical trials with new biologics, using biomarkers such as exhaled nitric oxide, sputum and tissue eosinophilia as endpoints, has occurred.

Breathborne Biomarkers and the Human Volatilome

Breathborne Biomarkers and the Human Volatilome
Author : Jonathan Beauchamp,Cristina Davis,Joachim Pleil
Publisher : Elsevier
Release Date : 2020-06-06
Category : Science
Total pages :722
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Breathborne biomarkers carry information on the state of human health, and their role in aiding clinical diagnosis or in therapeutic monitoring has become increasingly important as advances in the field are made. Breathborne Biomarkers and the Human Volatilome, Second Edition, provides a comprehensive update and reworking of the 2013 book Volatile Biomarkers, by Anton Amann and David Smith. The new editing team has expanded this edition beyond volatile organic compounds to cover the broad field of breath analysis, including the many exciting developments that have occurred since the first edition was published. This thoroughly revised volume includes the latest discoveries and applications in breath research from the world's foremost scientists, and offers insights into related future developments. It is an ideal resource for researchers, scientists, and clinicians with an interest in breath analysis. Presents recent advances in the field of breath analysis Includes an extensive overview of established biomarkers, detection tools, disease targets, specific applications, data analytics, and study design Offers a broad treatise of each topic, from basic concepts to a comprehensive review of discoveries, current consensus of understanding, and prospective future developments Acts as both a primer for beginners and a reference for seasoned researchers

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications

Volatile Organic Compound Analysis in Biomedical Diagnosis Applications
Author : Raquel Cumeras,Xavier Correig
Publisher : CRC Press
Release Date : 2018-11-22
Category : Science
Total pages :272
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This volume presents a thought-provoking state-of-the-art picture of how volatile compounds are used in metabolomics, currently a hot topic in the metabolomics field. It provides a thorough description of what volatile organic compounds (VOCs) are, why they are important in biomedicine, and what the analytical platforms are used. It also looks at multivariate analysis and databases needs. Because VOCs are end-up compounds of metabolic processes, volatiles can be linked to different diseases or pathologies for both diagnosis and prognosis. The authors provide authoritative information and guidance on the analytical and statistical techniques used and how to identify, and they review the main current areas of application, which include breath metabolomics, cancer diagnosis, and microbial volatiles. Key Features: Presents a thorough overview of volatile research in biomedical applications Examines both gold standard techniques (metabolomics based) and artificial olfactory systems Reviews all aspects of volatile metabolites in biomedicine research, from origin to detection platforms Describes relevant diseases diagnosis and prognosis achievements, including cancer

Volatile Organic Compounds in Blood as Biomarkers of Exposure to JP-8 Jet Fuel Among US Air Force Personnel

Volatile Organic Compounds in Blood as Biomarkers of Exposure to JP-8 Jet Fuel Among US Air Force Personnel
Author : Anonim
Publisher : Unknown
Release Date : 2016
Category :
Total pages :129
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Abstract : Objective: This study aimed to evaluate blood volatile organic compound (VOC) levels as biomarkers of occupational jet propulsion fuel 8 (JP-8) exposure while controlling for smoking. Methods: Among 69 Air Force personnel, post-shift blood samples were analyzed for components of JP-8, including ethylbenzene, toluene, o -xylene, and m/p -xylene, and for the smoking biomarker, 2, 5-dimethylfuran. JP-8 exposure was characterized based on self-report and measured work shift levels of total hydrocarbons in personal air. Multivariate regression was used to evaluate the relationship between JP-8 exposure and post-shift blood VOCs while controlling for potential confounding from smoking. Results: Blood VOC concentrations were higher among US Air Force personnel who reported JP-8 exposure and work shift smoking. Breathing zone total hydrocarbons was a significant predictor of VOC blood levels, after controlling for smoking. Conclusions: These findings support the use of blood VOCs as a biomarker of occupational JP-8 exposure.

Volatile Aldehydes in Breath and Tissues as Biomarkers of Carcinogenesis

Volatile Aldehydes in Breath and Tissues as Biomarkers of Carcinogenesis
Author : Susan Elizabeth Ebeler
Publisher : Unknown
Release Date : 1993
Category :
Total pages :202
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Handbook of Spectroscopy

Handbook of Spectroscopy
Author : G¿nter Gauglitz,David S. Moore
Publisher : John Wiley & Sons
Release Date : 2014-05-05
Category : Science
Total pages :1993
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This second, thoroughly revised, updated and enlarged edition provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that may be derived from spectra. It also features new chapters on spectroscopy in nano-dimensions, nano-optics, and polymer analysis. Clearly structured into sixteen sections, it covers everything from spectroscopy in nanodimensions to medicinal applications, spanning a wide range of the electromagnetic spectrum and the physical processes involved, from nuclear phenomena to molecular rotation processes. In addition, data tables provide a comparison of different methods in a standardized form, allowing readers to save valuable time in the decision process by avoiding wrong turns, and also help in selecting the instrumentation and performing the experiments. These four volumes are a must-have companion for daily use in every lab.

Omics Approaches in Breast Cancer

Omics Approaches in Breast Cancer
Author : Debmalya Barh
Publisher : Springer
Release Date : 2014-10-13
Category : Medical
Total pages :545
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Breast cancer is the most common cancer in females that accounts for highest cancer specific deaths worldwide. In the last few decades research has proven that breast cancer can be treated if diagnosed at early stages and proper therapeutic strategy is adopted. Omics-based recent approaches have unveiled the molecular mechanism behind the breast tumorigenesis and aid in identification of next-generation molecular markers for early diagnosis, prognosis and even the effective targeted therapy. Significant development has taken place in the field of omics in breast cancer in the last decade. The most promising omics approaches and their outcomes in breast cancer have been presented in this book for the first time. The book covers omics technologies and budding fields such as breast cancer miRNA, lipidomics, epigenomics, proteomics, nutrigenomics, stem cell, pharmacogenomics and personalized medicine and many more along with conventional topics such as breast cancer management etc. It is a research-based reference book useful for clinician-scientists, researchers, geneticists and health care industries involved in various aspects of breast cancer. The book will also be useful for students of biomedicine, pathology and pharmacy.

Lung Cancer

Lung Cancer
Author : Karen L. Reckamp
Publisher : Demos Medical Publishing
Release Date : 2010-10-25
Category : Medical
Total pages :368
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Lung Cancer: Over the course of the last decade, the treatment of lung cancer has evolved quite rapidly. New scientific and clinical advances have modified the standard of care and led to improved patient outcomes. At the same time, the treatment of lung cancer has become increasingly complex, requiring the comprehensive review and assessment of multiple issues, genetics, radiology, surgery, reconstruction, chemotherapy, and more. As a result the harmony and open communication between these specialties facilitated by a multidisciplinary team approach are crucial in providing the best care to patients and ensuring successful treatment. Lung Cancer: A Multidisciplinary Approach to Diagnosis and Management, written by a multidisciplinary team of authors representing a range of disciplines, is a valuable resource for physicians, fellows, nurses, physician assistants, physical therapists, and all health care providers involved in the treatment of lung cancer. Lung Cancer: A Multidisciplinary Approach to Diagnosis and Management summarizes the state-of-the-art issues related to the treatment of lung cancer and describes an approach for optimal multidisciplinary care for individuals who have been diagnosed with lung cancer or who are at higher risk to develop lung cancer. About the Series: The Current Multidisciplinary Oncology series edited by Charles R. Thomas consolidates and integrates the varied aspects of multidisciplinary care for major topics in oncology, including breast, lung, prostrate, head and neck and more. The volumes in the Current Multidisciplinary Oncology series will represent all related topic areas, including oncology, radiation oncology, pain, pathology, imaging, psychological support and the primary disease. In addition, each volume includes a chapter focusing on special populations and the disease's impact / difference on them, and discussion of future directions and quality of life issues. In addition each volume has a chapter written by a private practice oncologist. All Current Multidisciplinary Oncology titles provide: Consolidation and integration of the varied aspects of multidisciplinary care for major topics in oncology Coverage of all related topic areas, including medical and surgical oncology, radiation oncology, pain, pathology, imaging, psychological support, and the primary disease A chapter focusing on special populations and the disease's impact / difference on them A chapter on community practice written by a private practice oncologist Discussion of quality-of-life issues

Cancer Biomarkers

Cancer Biomarkers
Author : Debmalya Barh,Angelo Carpi,Mukesh Verma,Mehmet Gunduz
Publisher : CRC Press
Release Date : 2014-01-30
Category : Medical
Total pages :951
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Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers. It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information. Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single Volume The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers. Emphasizes the Importance of Volatile Markers in Early Cancer Diagnosis Presents noninvasive early molecular markers in urological cancers Describes gynecological and endocrine cancer markers Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers Addresses hematological malignancies Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin’s lymphoma, and multiple myeloma Provides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanoma This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.

Biosensing Technologies for the Detection of Pathogens

Biosensing Technologies for the Detection of Pathogens
Author : Toonika Rinken,Kairi Kivirand
Publisher : BoD – Books on Demand
Release Date : 2018-03-21
Category : Medical
Total pages :216
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Rapid multiplex detection of pathogens in the environment and in our food is a key factor for the prevention and effective treatment of infectious diseases. Biosensing technologies combining the high selectivity of biomolecular recognition and the sensitivity of modern signal detection platforms are a prospective option for automated analyses. They allow rapid detection of single molecules as well as cellular substances. This book, including 12 chapters from 50 authors, introduces the principles of identification of specific pathogen biomarkers along with different biosensor-based technologies applied for pathogen detection.

Photoacoustic Analyser for Volatile Organic Compound Lung Cancer Biomarkers

Photoacoustic Analyser for Volatile Organic Compound Lung Cancer Biomarkers
Author : Yannick Saalberg
Publisher : Unknown
Release Date : 2018
Category :
Total pages :129
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